• Journal of the Korean Society of Propulsion Engineers
• /
• v.16 no.6
• /
• pp.41-47
• /
• 2012

It is very important to predict the nonlinear behavior of combustion instability such as transition phenomena and limit cycle amplitude for fully understanding and controlling the instabilities. These nonlinear instability characteristics are highly dependent upon the flames' nonlinear dynamics in a gas turbine premixed combustor. In this study, nonlinear instability TA(Thermo-acoustic) models were introduced by applying the concept of flame describing function to the thermoacoustic analysis method. As a result of model development, for a given combustor length, the growth rate of instability was greatly affected by the change in amplitude, although the instability frequency was not. Further researches under various operating conditions and model validation on limit cycle amplitude are required.

• Clinical and Experimental Reproductive Medicine
• /
• v.35 no.1
• /
• pp.69-76
• /
• 2008

Objective: The purposes of this study were to determine the distribution of follicle-stimulating hormone receptor (FSHR) genotypes in infertile Korean women and to evaluate the relationship between FSHR genotypes and clinical outcomes of IVF-ET cycles. Methods: Genomic DNA was extracted from peripheral blood in 1, 020 of infertile Korean women. Genotypes of FSHR at Thr307Ala (T/A) and Asn680Ser (N/S) were screened by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis. Clinical outcomes related to the genotypes of FSHR were evaluated in IVF-ET cycles (n=302) with controlled ovarian hyperstimulation (COH) of infertile women under 40 years old. Results: In a population of 1, 020 infertile Korean women, the frequency of TT/NN, TA/NS and AA/SS for the major variant Thr307Ala and Asn680Ser was 44.80%, 41.96% and 10.49%, respectively. There was no significant difference in characteristics of ovarian response and clinical pregnancy rate among the major genotypes of FSHR in IVF-ET cycles with COH. However, implantation rate of AA/SS patients was significantly higher than that of TT/NN patients (24.5% vs 15.7%, p<0.05). Conclusion: This study showed that FSHR genotype was not directly associated with ovarian response in IVF-ET cycles with COH. The relationship between clinical outcomes and FSHR genotypes of patients should be substantiated by further studies.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.7
• /
• pp.2951-2957
• /
• 2014

Background: Gastric carcinogenesis is a complicated process that involves environmental and genetic factors like interleukin-4 (IL-4) and IL-8. Single nucleotide polymorphisms in their genes are associated with changed levels of gene expression. Here, we investigated the association between IL4-590 C>T and IL8-251T>A and gastric cancer (GC) risk in Sichuan of Southwestern China. Materials and Methods: We surveyed the research subjects using a self-designed questionnaire with questions on demographic factors and putative risk factors. Approximately 2-5ml of whole blood was collected after field survey to analyze IL4-590 C>T and IL8-251T>A genotypes using MALDI-TOF MS. Results: Our study recruited 308 pairs of GC patients and controls, including 224 (72.7%) men and 84 (27.3%) women in each group. There were 99 cardia and 176 noncardia GC patients in the case group. The case and control groups had an average age of $57.7{\pm}10.6$ ($mean{\pm}SD$) and $57.6{\pm}11.1$ years. GC patients reported a significantly greater proportion of family history of cancer (29.9% vs 10.7%, p<0.01) and drinking (54.6% vs 43.2%, p<0.01) than did controls. Variant genotypes of IL-4-590 C>T and IL-8-251 T>A were not associated with overall GC risk (adjusted OR, 0.89; 95%CI, 0.61-1.28 for CT or CC vs TT; adjusted OR, 1.14; 95%CI, 0.86-1.79 for TA or AA vs TT). Stratification analysis of two SNPs for risk by subsites only found that variant IL-8-251 TA or AA genotype was associated with increased noncardia GC risk (adjusted OR, 2.58; 95%CI, 1.19-5.57). We did not observe interactions between the IL-8-251 T>A genotype and smoking (adjusted OR, 0.38; 95%CI, 0.08-1.79) or drinking (adjusted OR, 0.36; 95%CI, 0.08-1.65) for risk of noncardia GC. Conclusions: Our data indicate no association between the two SNPs of IL-4-590 and IL-8-251 with overall GC risk, while the IL-8-251 TA or AA genotype conferred risk of cardia GC. Our findings contribute to the evidence body for risk of SNPs associated with the development of gastric cancer in this region.

• Analytical Science and Technology
• /
• v.17 no.6
• /
• pp.496-513
• /
• 2004

This study was carried out to evaluate the performance of sampling and analytical methodology used for the measurement of toxic volatile organic compounds (VOCs) in the ambient air. VOCs were determined by the adsorbent tube sampling and automatic thermal desorption coupled with GC/MSD analysis. Target analytes were 33 compounds including major aromatic compounds such as BTEX, and halogenated compounds. The methodology was investigated with a wide range of different adsorbents which are commercially available and have been frequently adopted for the VOC measurement. A total of 10 adsorbents were tested in this study: 6 carbon-based adsorbents such as Carbotrap, Carbopack B, Carbosieve S-III, Carboxen 1000, Carbotrap C, Activated Charcoal; and 4 polymer-based adsorbents including Tenax, Porapak Q, Chromosorb 102, and Chromosorb 106. The sampling performance was evaluated with respect to the sampling capacity of VOCs with single-adsorbent and multiple-adsorbents methods for standard samples and field samples. As a result, the best adsorbents for single-adsorbent method in the sampling of toxic organic compounds (including benzene, toluene, xylenes etc.) appeared to be Carbotrap, Carbopack B and Tenax TA. On the other hand, Chromosorb 102, Chromosorb 106 and Porapak Q were found to be unsuitable adsorbents for VOC measurement based on thermal desorption method. Multi-adsorbent packings were evaluated with 4 carbon-based adsorbents, which classified by 3 combination sets of double adsorbents and 2 combination sets of triple adsorbents. The results indicated that the most suitable combination for toixc VOC measurements is Carbotrap C with Carbotrap. Multi-sorbents tubes packed with a strong adsorbent such as Carbosieve S-III or Carboxen 1000 were found to be relatively unsuitable for several compounds, not only owing to the effect of migration of adsorbed compounds from weaker adsorbent to stronger adsorbent, but to hydrophobic nature of the adsorbents. Therefore, it should be addressed that selection of a proper adsorbent (or combination of multi sorbents) is extremely important to obtain reliable data for the concentrations of toxic VOCs in indoor and outdoor environments.

• Analytical Science and Technology
• /
• v.22 no.6
• /
• pp.488-497
• /
• 2009

In this study, analytical methodology for several organic fatty acids (OFA: propionic acid (PA), butyric acid (BA), isovaleric acid (IA), and valeric acid (VA)) designated as new offensive odorants in Korea (as of year 2010) was investigated along with some odorous VOCs (styrene, toluene, xylene, methyl ethyl ketone, methyl isobutyl ketone, butyl acetate, and isobutyl alcohol). For this purpose, working standards (WS) containing all of these 13 compounds were loaded into adsorption tube filled with Tenax TA, and analyzed by gas chromatography (GC) system thermal desorber interfaced with. The analytical sensitivities of organic fatty acids expressed in terms of detection limit (both in absolute mass (ng) and concentration (ppb)) were lower by 1.5-2 times than other compounds (PA: 0.24 ng (0.16 ppb), BA: 0.19 ng (0.11 ppb), IA: 0.15 ng (0.07 ppb), and VA: 0.28 ng (0.13 ppb)). The precision of BA, IA, and VA, if assessed in terms of relative standard error (RSE), maintained above 5%, while the precison of other compounds were below 5%. The reproducibility of analysis improved with the aid of internal standard calibration (PA: $1.1{\pm}0.4%$, BA: $10{\pm}0.46$, IA; $12{\pm}0.3%$, VA: $4{\pm}0.1%$), respectively. The results of this study showed that organic fatty acid can be analyzed using adsorption tube and thermal desorber in a more reliable way to replace alkali absorption method introduced in the odor prevention law of the Korea Ministry of Environment (KMOE).

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.35 no.1
• /
• pp.9-17
• /
• 2015

Interface behavior of concrete-infilled steel tube (CFT) was investigated based on the experimental observations and numerical analyses. Laboratory tests were performed for twelve CFTs that consisted of two different cases of diameters where each diameter case was composed of three different cases of shear span length. Thereby, diameter and shear span parameters were considered to prove the question of whether there exists interface slip between steel tube and infilled-concrete. Confining effect of steel tube to infilled concrete was also investigated by measuring lateral strain as well as longitudinal strain. Based on the study, it was concluded that confining effect of steel tube to infilled-concrete is not influential under flexural loading and therefore, the sectional analysis is an effective way to estimate the flexural strength of CFT.

• The Korean Journal of Ecology
• /
• v.16 no.4
• /
• pp.439-457
• /
• 1993

The present study was undertaken to classify and describe the forest vegetation on Imha-dam area, located at the northern part of Kyungsang-pookdo, Korea by the phytosociological method of the Z-M school. The field investigations were carried out in 60 plots around the dam area from May 1, 1991 to October 10, 1992. The vegetation data obtained were classified by the table comparison method. As a result, the following vegetation units were recognized: A. Pinus densiflova community A-a. Miscanthus sinensis group A-b. Carex humilzs group A-c. Typical group B. Quercetum variabili-serratae Kobayashi, Muranaga et Takeda 1976 C. Robinin pseudo-acacia-Conzmeli~ta comnzultis community D. Larix leptolepis community The vascular plant species of these forest communities consist of 63 families, 144 genera, 191 species and 30 varieties. Also the relationship of the vegetation units with their environments such as altitude, slope, topography and soil condition was discussed here. On the basis of the floristic composition, life-form spectrum and soil analysis, a sere for the forest vegetation was proposed as follows: Rohinia pseitdo-acacia-Conz~neli~za communis community and Larix leptolepis community $\rightarrow$ Pinus densiflora community $\rightarrow$ Quercetunz variahili-serratae $\rightarrow$ Quercus mongolica community. Lastly, relating to the nature conservation of dam area, some of plans were discussed.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.34 no.6
• /
• pp.579-586
• /
• 2010

With the development of micrototal analysis systems (${\mu}TAS$), which is a result of enhancement of MEMS technology, rapid progress has been achieved in medical and biological research. The study of lab-on-a-chip (LOC) devices, which are types of ${\mu}TAS$ and which integrate the functions of mixing and analyzing tiny amounts of samples and reagents on one chip, has actively progressed. An LOC comprises microfluidic components such as micromixers and micropumps. Because the flow in a microfluidic system is generally laminar, it is very difficult to efficiently mix and feed fluid reagents. This paper presents the design and the method of fabrication of an MHD micropump for mixing fluids. By using this micropump, fluids are simultaneously mixed and pumped; this is achieved by coupling the Lorentz force and force exerted by an electric charge moving in an electric field.

• Journal of Communications and Networks
• /
• v.3 no.4
• /
• pp.383-395
• /
• 2001

Recent measurement and simulation studies have revealed that wide area network traffic displays complex statistical characteristics-possibly multifractal scaling-on fine timescales, in addition to the well-known properly of self-similar scaling on coarser timescales. In this paper we investigate the performance and network engineering significance of these fine timescale features using measured TCP anti MPEG2 video traces, queueing simulations and analytical arguments. We demonstrate that the fine timescale features can affect performance substantially at low and intermediate utilizations, while the longer timescale self-similarity is important at intermediate and high utilizations. We relate the fine timescale structure in the measured TCP traces to flow controls, and show that UDP traffic-which is not flow controlled-lacks such fine timescale structure. Likewise we relate the fine timescale structure in video MPEG2 traces to sub-frame encoding. We show that it is possibly to construct a relatively parsimonious multi-fractal cascade model of fine timescale features that matches the queueing performance of both the TCP and video traces. We outline an analytical method ta estimate performance for traffic that is self-similar on coarse timescales and multi-fractal on fine timescales, and show that the engineering problem of setting safe operating points for planning or admission controls can be significantly influenced by fine timescale fluctuations in network traffic. The work reported here can be used to model the relevant characteristics of wide area traffic across a full range of engineering timescales, and can be the basis of more accurate network performance analysis and engineering.

• Food Science of Animal Resources
• /
• v.33 no.6
• /
• pp.744-751
• /
• 2013

The objective of this study was to assess the physicochemical and sensory changes of a kefir manufactured by a two-step fermentation (MTY, $1^{st}$ step: $37^{\circ}C$ for 9 h; $2^{nd}$ step: $24^{\circ}C$ for 15 h) and compare it with kefirs produced by two conventional methods (GTY, fermentation at $37^{\circ}C$ for 24 h; KEY, $22^{\circ}C$ for 24 h). Rapid changes in pH and titratable acidity (TA) were observed in samples from all three manufacturing methods during fermentation process and storage period. Lactic acid bacteria (LAB) counts of MTY increased gradually up to 12 h of fermentation, reaching 9.28 Log CFU/mL, with maximum value observed in this experiment of 9.48 Log CFU/mL. The LAB counts of all samples decreased significantly during storage. The highest viscosity was observed for MTY (1750-1771 cPs), compared with the lowest viscosity observed for KEY (1250-1277 cPs). The viscosity of all samples increased slightly during storage (1250-1805 cPs, p<0.05), as well as carbon dioxide content (0.01-1.36%, p<0.05), except for GTY. The most significant increase in alcohol concentration during storage period was seen in MTY from 0.01% to 1.36% (p<0.05). MTY scored significantly higher in most items of the sensory analysis, indicating that the product manufactured by the two-step fermentation method is more acceptable compared with conventionally produced kefirs.