• Title/Summary/Keyword: T800

Search Result 687, Processing Time 0.035 seconds

Hepatotoxicity in Rats Treated with Dimethylformamide or Toluene or Both

  • Kim, Ki-Woong;Chung, Yong Hyun
    • Toxicological Research
    • /
    • v.29 no.3
    • /
    • pp.187-193
    • /
    • 2013
  • The effects of toluene in dimethylformamide (DMF)-induced hepatotoxicity were investigated with respect to the induction of cytochrome P-450 (CYP) and the activities of related enzymes. The rats were treated intraperitoneally with the organic solvents in olive oil (Single treatment groups: 450 [D1], 900 [D2], 1,800 [D3] mg DMF, and 346 mg toluene [T] per kg of body weight; Combined treatment groups: D1+T, D2+T, and D3+T) once a day for three days, while the control group received just the olive oil. Each group consisted of 4 rats. The activities of the xenobiotic metabolic enzymes and the hepatic morphology were assessed. The immunoblots indicated that the expression of CYP2E1 was considerably enhanced depending on the dosage of DMF and the CYP2E1 blot densities were significantly increased after treatment with both DMF and toluene, compared to treatment with DMF alone. The activities of glutathione-S-transferase and glutathione peroxidase were either decreased or remained unaltered after treatment with DMF and toluene, whereas the lipid peroxide levels were increased with increasing dosage of DMF and toluene. The liver tissue in the D3 group (1,800 mg/kg of DMF) showed signs of microvacuolation in the central vein region and a large necrotic zone around the central vein, in rats treated with both DMF (1,800 mg/kg) and toluene (D3T). These results suggest that the expression of CYP2E1 is induced by DMF and enhanced by toluene. These changes may have facilitated the accelerated formation of N-methylformamide (NMF) from toluene, and the generated NMF may directly induce liver damage.

Effect of Sowing Season on the Growth and Dry Matter Yield Legumes in Different Legume-Grass Mixtures according to Altitude (표고별 파종시기가 서로다른 두과 - 화본과 혼파초지에서 두과목초의 생육 및 건물수량에 미치는 영향)

  • 정의수;김현섭
    • Journal of The Korean Society of Grassland and Forage Science
    • /
    • v.12 no.3
    • /
    • pp.153-160
    • /
    • 1992
  • This experiment was conducted to investigate the adaptability of legume in different legume-grass mixtures according to altitude(600, 800, lOOOm a.s.1.) in the alpine area. The experimental plot was allocated as a split plot design with three replications. The main plots were sowing season(spring and fall) and subplots legume-grass mixture(alfa1fa-grass, red clover-grass and white clover-grass mixture). The results obtained are summarized as follows: 1. At 600m, in case of sowing alfalfa, red clover and white clover in fall. each legume of legume-grass mixtures was consistuted about 30% without between-year variation and then all legumes at fall sowing could grow. 2. At 800m, in case of sowing white clover in spring this species was consistuted about 14.7 % at the last cutting without severe between-year variation. 3. At 1000m, only white clover sown in spring like at 800m was somewhat maintained without severe between-year variation. 4. Percentage and DM yield of legume considerably decreased with the rise of altitude and alfalfa couldn't grow more than 800m.

  • PDF

Development of the Advanced Manganese-Based Sorbent for Hot Coal Gas Desulfurization (고온 석탄 가스 탈황을 위한 개선된 망간계 탈황제 개발)

  • Shon, Byung-Hyun;Choi, Eun-Hwa;Cho, Ki-Chul;Jeon, Dae-Young;Oh, Kwang-Joong
    • Journal of Korean Society of Environmental Engineers
    • /
    • v.22 no.2
    • /
    • pp.291-302
    • /
    • 2000
  • This experiments have been made to develop of manganese-based sorbent for the removal of hydrogen sulfide from hot coal gases. Manganese-based sorbent were tested in an ambient-pressure fixed-bed reactor to determine steady state $H_2S$ concentrations, breakthrough times and feasibility of the sorbent when subjected to cycle sulfidation and regeneration testing. Effects of particle size of sorbent, temperature of sulfidation, regeneration temperature and regeneration characteristics on the $H_2S$ removal efficiency were investigated. Experimental results showed that the $H_2S$ removal efficiency was optimal when the temperature was about $800^{\circ}C$ and the smaller particle size, the better $H_2S$ removal efficiency but in the range of 0.214~0.631mm didn't influence it much. The equilibrium constant(K) is represented as a log(K)=3.396/T-1.1105 and the utilization efficiency of sorbents was about 92% at $800^{\circ}C$. Regeneration in air produced $SO_2$ concentration as high as 8.5% at $800^{\circ}C$, 8.4% at $850^{\circ}C$, and 8.8% at $900^{\circ}C$ and may be used in sulfuric acid production.

  • PDF

Synthesis and characterization of powders in the La-Al-Si-O system

  • Kyoung Jin Kim;Kwang Suk Joo;Kun Chul Shin;Keun Ho Auh;Kyo Seon Kim
    • Journal of the Korean Crystal Growth and Crystal Technology
    • /
    • v.9 no.5
    • /
    • pp.475-479
    • /
    • 1999
  • Langasite ($La_{3}Ga_{5}SiO_{14}$) was found to have wide application as a promising piezoelectric material. It has high thermal stability of the frequency and large electromechanical coupling factor. For the further development of new compounds with langasite type structure, powders in the La-Al-Si-O system were synthesized by a modified Pechini process. The evolution of the crystalline phase during calcination was studied using TG-DTA, XRD and TEM for the precursor powders. Decomposition proceeded via dehydration and removal of excess solvents at low temperatures ($T<500^{\circ}C$), followed by the crystallization of lanthanum aluminum silicate ($T>800^{\circ}C$) and phase transformation to $LaAlO_{3}$ phase ($T>1200^{\circ}C$). Transmission electron microscopy (TEM) of the calcined powders showed diffuse hollow rings corresponding to an amorphous phase at $800^{\circ}C$ and clear diffraction patterns corresponding to a crystalline phase from the P321 space group ($T<1200^{\circ}C$) and the R3m ($T<1200^{\circ}C$).

  • PDF

Nonparametric Regression with Left-Truncated and Right-Censored Data

  • Park, Jinho
    • Communications for Statistical Applications and Methods
    • /
    • v.6 no.3
    • /
    • pp.791-800
    • /
    • 1999
  • Gross and Lai(1996) proposed a new approach for ordinary regression with left-truncated and right-censored (I.t.r.c) data. This paper shows how to apply nonparametric algorithms such as multivariate adaptive regression splines to 1.t.r.c data.

  • PDF

Nutrient Removal Characteristics on Organic Material Loadings in Submerged Flat Sheet Type Sequencing Batch Membrane Reactor (침지식 평판형 연속회분식 박반응기에서 유입 유기물 부하의 변화에 따른 영양염류의 제거 특성)

  • Kim, Seung-Geon;Lee, Ho-Won;Kang, Yeung-Joo
    • Membrane Journal
    • /
    • v.20 no.3
    • /
    • pp.241-248
    • /
    • 2010
  • The effect of organic material loadings on nutrient removal characteristics were investigated in sequencing batch reactor, in which a flat sheet type microfiltration membrane with a pore size of $0.4\;{\mu}m$ was submerged. Three organic concentrations of 200 mg/L (Run-1), 400 mg/L (Run-2) and 800 mg/L (Run-3) were carried out continuously to identify their effect on the filtration performance and nutrient removal. The removal efficiencies of T-N and T-P were increased with the increase of COD/N and COD/P. The T-N removal efficiencies of Run-1, Run-2 and Run-3 were 28.1, 32.6 and 90.4%, the average concentrations of T-N in permeate were 32.0, 30.0, and 4.3 mg/L, respectively. The T-P removal efficiencies of Run-1, Run-2 and Run-3 were 13.6, 35.3 and 93.1%, the average concentrations of T-P in permeate were 3.11, 2.33, and 0.25 mg/L, respectively.

Hardware Design with Efficient Pipelining for High-throughput AES (높은 처리량을 가지는 AES를 위한 효율적인 파이프라인을 적용한 하드웨어 설계)

  • Antwi, Alexander O.A;Ryoo, Kwangki
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2017.10a
    • /
    • pp.578-580
    • /
    • 2017
  • IoT technology poses a lot of security threats. Various algorithms are thus employed in ensuring security of transactions between IoT devices. Advanced Encryption Standard (AES) has gained huge popularity among many other symmetric key algorithms due to its robustness till date. This paper presents a hardware based implementation of the AES algorithm. We present a four-stage pipelined architecture of the encryption and key generation. This method allowed a total plain text size of 512 bits to be encrypted in 46 cycles. The proposed hardware design achieved a maximum frequency of 1.18GHz yielding a throughput of 13Gbps and 800MHz yielding a throughput of 8.9Gbps on the 65nm and 180nm processes respectively.

  • PDF