• Title/Summary/Keyword: T24

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사람 유래의 MCF10A, Chang liver및 HaCaT 세포의 소핵형성 및 세포형질전환에 미치는 2,3,7,8-Tetrachlorodibenzo-p-dioxin의 영향

  • 엄미옥;박미영;김종원;박미선;한의식;오혜영;정해관
    • Environmental Mutagens and Carcinogens
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    • v.24 no.2
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    • pp.91-98
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    • 2004
  • Although 2,3,7,8-tetrachlorodibenzo-p-dioxin(TCDD) is a powerful carcinogen in several species, limited model system exist to study carcinogenicity of this compound at cellular level. To enhance our under-standing of carcinogenicity of TCDD at cellular level, we investigated micronucleus (MN) frequency as a index of genetic toxicity and whether TCDD can transform the human cells in culture. Normal human cell lines, skin keratinocyte HaCaT, Chang liver and breast MCF10A cells were used. TCDD did not affect the cell viability of the Chang liver, HaCaT and MCF10A cells. The frequency of micronucleus was increased after treatment of TCDD for 24hr in Chang liver and HaCaT cells, but not changed in MCF10A cells. And we observed putative transformed cells in Chang liver cells exposed to 1 $\mu$M TCDD for 2 weeks. The putative transformed cells were also observed in HaCaT cells with subsequent exposure to TCDD (0.1, 1, 10, 100 nM) for 2 weeks after initial exposure to MNNG, but not observed in MCF10A cells. Collectively, these results indicate that the ability of TCDD to induce micronuclei may be involved in cellular transformation of Chang liver and HaCaT cells. Our putative TCDD-transformed cells of Chang liver and HaCaT are expected to provide a clue to the elucidation of TCDD-induced transformation pathway.

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Probabilistic Analysis of Code-Reuse Attacks and Defenses in IoT

  • Ho, Jun-Won
    • International Journal of Internet, Broadcasting and Communication
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    • v.9 no.1
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    • pp.24-28
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    • 2017
  • In the Internet of Things (IoT), resource-limited smart devices communicate with each other while performing sensing and computation tasks. Thus, these devices can be exposed to various attacks being launched and spread through network. For instance, attacker can reuse the codes of IoT devices for malicious activity executions. In the sense that attacker can craft malicious codes by skillfully reusing codes stored in IoT devices, code-reuse attacks are generally considered to be dangerous. Although a variety of schemes have been proposed to defend against code-reuse attacks, code randomization is regarded as a representative defense technique against code-reuse attacks. Indeed, many research have been done on code randomization technique, however, there are little work on analysis of the interactions between code randomization defenses and code-reuse attacks although it is imperative problem to be explored. To provide the better understanding of these interactions in IoT, we analyze how code randomization defends against code-reuse attacks in IoT and perform simulation on it. Both analysis and simulation results show that the more frequently code randomizations occur, the less frequently code-reuse attacks succeed.

An Estimation of Constraint Factor on the ${\delta}_t$ Relationship (J-적분과 균열선단개구변위에 관한 구속계수 m의 평가)

  • 장석기
    • Journal of Advanced Marine Engineering and Technology
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    • v.24 no.6
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    • pp.24-33
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    • 2000
  • This paper investigates the relationship between J-integral and crack tip opening displacement, ${\delta}_t$ using Gordens results of numerical analysis. Estimation were carried out for several strength levels such as ultimate, flow, yield, ultimate-flow, flow-yield stress to determine the influence of strain hardening and the ratio of crack length to width on the $J-{\delta}_t$ relationship. It was found that for SE(B) specimens, the $J-{\delta}_t$ relationship can be applied to relate J to ${\delta}_t$ as follows $J=m_j{\times}{\sigma}_i{\times}{\delta}_t$ where $m_j=1.27773+0.8307({\alpha}/W)$, ${\sigma}_i:{\sigma}_U$, ${\sigma}_{U-F}={\frac{1}{2}} ({\sigma}_U+{\sigma}_F$), ${\sigma}_F$, ${\sigma}_F}$ $Y=({\sigma}_F+{\sigma}_Y)$, ${\sigma}_Y$

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Influence of growth Temperature on the Formation of 10 monolayer-thick InGaAs Quantum dots formed with 5 repetitions of 1 monolayer-thick InAs and 1 monolayer-thick GaAs

  • Song, J.D.;Han, I.K.;Choi, W.J.
    • Applied Science and Convergence Technology
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    • v.24 no.6
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    • pp.254-256
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    • 2015
  • Effect of growth temperature ($T_g$) on the structural and optical properties of $In_{0.5}Ga_{0.5}As$ atomic layer epitaxial (ALE) quantum dots (QDs) is investigated in the range of $T_g=480-510^{\circ}C$. $In_{0.5}Ga_{0.5}As$ ALE QDs consist of 5 periods of short-period superlattices (SPSs) of 1 monolayer-thick InAs and GaAs. Number of coalescent QDs decreases as $T_g$ increases, and they disappear at $T_g=510^{\circ}C$. As $T_g$ increases in the range of $480-495^{\circ}C$, sizes of QDs increase, and densities of QDs decrease due to merge of QDs. On the contrary, although sizes of QDs are maintained at $T_g=495-510^{\circ}C$, densities of QDs decrease. This is attributed to the desorption of material-mainly indium-during the growth interruption. This conjecture is supported by the optical properties of the QDs as a function of $T_g$. As a result, we propose that optimum growth temperature of the QD is $495^{\circ}C$ with less repetition of SPSs than 5.

Comparison of Hardness and Damping Capacities of Mg-Al Alloy Subjected to T6 Heat Treatment and Low Temperature Long Term Isothermal Aging (T6 열처리 및 저온 장시간 등온 시효한 Mg-Al 합금의 경도 및 진동감쇠능 비교)

  • Joong-Hwan Jun
    • Journal of the Korean Society for Heat Treatment
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    • v.36 no.5
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    • pp.277-284
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    • 2023
  • Hardness and damping characteristics of fine discontinuous precipitates (DPs) microstructure generated by low temperature long term isothermal aging were investigated in comparison with those of T6 heat-treated microstructure composed of DPs and continuous precipitates (CPs) in Mg-9%Al alloy. In this study, T6 and fine DPs microstructures were obtained by isothermal aging at 453 K for 24 h and at 413 K for 336 h, respectively, after solution treatment at 693 K for 24 h. The DPs microstructure exhibited higher hardness than the T6 microstructure, which is related to the lower (α + β) interlamellar spacing of the DPs. The DPs microstructure possessed better damping capacity than the T6 microstructure in the strain-amplitude independent region, whereas in the strain-amplitude dependent region, the reverse behavior was observed. The damping tendencies depending on strain-amplitude were discussed based on the microstructural features of the T6 and DPs microstructures.

Relevance of E- Learning and Quality Development in Higher Education

  • Arshi Naim;Sahar Mohammed Alshawaf
    • International Journal of Computer Science & Network Security
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    • v.24 no.1
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    • pp.187-195
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    • 2024
  • This is an extended paper explaining the role of E-learning and quality development in the current situation. Amid Covid:19, E-Learning has achieved a new miles stone in imparting education and all levels of institutions have transformed their learning platform from face to face to virtual learning. In this scenario E-Learning is facing two major challenges, first to ensure the ability of computer systems or software to exchange and make use of information on virtual platform (interoperability) and secondly, developing quality learning through e-Learning. To impart learning and teaching (L&T) through E-learning, Middle East University (MEU) has adopted Learning Management Services (LMS) through Blackboard. The university has three types of L&T methods; full online, Blended and Supportive. This research studies the concept, scope and dimensions of interoperability (InT) of E-Learning in MEU then the connection and interdependence between with quality development. In this paper we have described the support and the importance of finest standards and specifications for the objectives of InT of E-Learning and quality development in MEU. The research is based principally on secondary data observed from MEU E-Learning deanship. Also sample of 20 E-Learning experts at MEU were given closed ended as well as semi closed questionnaires for evaluating the assurance of InT of E-Learning and quality development. These experts are mainly certified online facilitators and admin staff. Results provide the verification of application and presence of InT of E-Learning and assured the quality development process in MEU.

THE NUMBER OF POINTS ON ELLIPTIC CURVES EA0:y2=x3+Ax OVER $\mathbb{F}$p MOD 24

  • Park, Hwa-Sin;You, Soon-Ho;Kim, Dae-Yeoul;Kim, Min-Hee
    • Honam Mathematical Journal
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    • v.34 no.1
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    • pp.93-101
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    • 2012
  • Let $E_A^B$ denote the elliptic curve $E_A^B:y^2=x^3+Ax+B$. In this paper, we calculate the number of points on elliptic curves $E_A^0:y^2=x^3+Ax$ over $\mathbb{F}_p$ mod 24. For example, if $p{\equiv}1$ (mod 24) is a prime, $3t^2{\equiv}1$ (mod p) and A(-1 + 2t) is a quartic residue modulo p, then the number of points in $E_A^0:y^2=x^3+Ax$ is congruent to 0 modulo 24.

TRANSIENT THERMOELASTIC STRESS ANALYSIS OF A THIN CIRCULAR PLATE DUE TO UNIFORM INTERNAL HEAT GENERATION

  • GAIKWAD, KISHOR R.;NANER, YOGESH U.
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.24 no.3
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    • pp.293-303
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    • 2020
  • The present work aims to analyzed the transient thermoelastic stress analysis of a thin circular plate with uniform internal heat generation. Initially, the plate is characterized by a parabolic temperature distribution along the z-direction given by T = T0(r, z) and perfectly insulated at the ends z = 0 and z = h. For times t > 0, the surface r = a is subjected to convection heat transfer with convection coefficient hc and fluid temperature T. The integral transform method used to obtain the analytical solution for temperature, displacement, and thermal stresses. The associated thermoelastic field is analyzed by making use of the temperature and thermoelastic displacement potential function. Numerical results are carried out with the help of computational software PTC Mathcad Prime-3.1 and shown in figures.

An Approach for Applying Network-based Moving Target Defense into Internet of Things Networks

  • Park, Tae-Keun;Park, Kyung-Min;Moon, Dae-Sung
    • Journal of the Korea Society of Computer and Information
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    • v.24 no.9
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    • pp.35-42
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    • 2019
  • In this paper, we propose an approach to apply network-based moving target defense into Internet of Things (IoT) networks. The IoT is a technology that provides the high interconnectivity of things like electronic devices. However, cyber security risks are expected to increase as the interconnectivity of such devices increases. One recent study demonstrated a man-in-the-middle attack in the statically configured IoT network. In recent years, a new approach to cyber security, called the moving target defense, has emerged as a potential solution to the challenge of static systems. The approach continuously changes system's attack surface to prevent attacks. After analyzing IPv4 / IPv6-based moving target defense schemes and IoT network-related technologies, we present our approach in terms of addressing systems, address mutation techniques, communication models, network configuration, and node mobility. In addition, we summarize the direction of future research in relation to the proposed approach.