• Korean Journal of Acupuncture
• /
• v.38 no.3
• /
• pp.140-150
• /
• 2021

Objectives : The increase of osteoclasts could cause osteoporosis and bone-related diseases. Also, the inhibition of osteoclast differentiation is important in treating bone-related diseases. Traditionally, Psoraleae Semen has been used for geriatric diseases, aging and musculoskeletal diseases. The purpose of this study is to investigate the effect of Psoraleae Semen ethanol extract (PS) on osteoclast differentiation and its function. Methods : To confirm the effect of PS on osteoclastogenesis and bone resorption activity, various levels of concentrations of PS (5, 10, 20 and 40 ㎍/ml) were tested on RAW 264.7 cells cultured with RANKL. We measured tartarate-resistant acid phosphatase (TRAP)-positive cells, TRAP activity, pit formation and F-actin ring formation. The expressions of nuclear factor of activated T-cells (NFATc1) and c-Fos were confirmed through western blot and reverse transcription- polymerase chain reaction (RT-PCR). Also, the expression of bone resorption and fusion-related genes in osteoclast was confirmed by RT-PCR. Results : PS decreased the number of TRAP-positive cells and the TRAP activity. In addition, PS significantly inhibited the formation of pit and F-actin ring. Furthermore, PS decreased the expression of osteoclast related genes. Conclusions : PS inhibits osteoclast differentiation and bone resorption ability through inhibition of the expression of osteoclast-related genes. This indicates that PS may be a potential therapeutic agent to osteoporosis by suppressing osteoclastogenesis.

• Korean Journal of Agricultural and Forest Meteorology
• /
• v.22 no.4
• /
• pp.279-286
• /
• 2020

The objective of this study was to assess the impact of El Niño on highland kimchi cabbage production for the period from 1991-2016 in South Korea. Years with less than 1.0 Oceanic Niño index (ONI) were classified into non El Niño years, while years with equal to or greater than 1.0 ONI were defined as El Niño years. The national average production (3,444 kg 10a-1) of high kimchi cabbage in El Niño years tended to be less than that in non El Niño years (3,722 kg 10a-1) with significant differences (p = 0.0042) in the production between these groups of years. The averaged production of highland kimchi cabbage of El Niño end years (3,289 kg 10a-1) was less than those of El Niño start years and non El Niño years by 310 and 433 kg 10a-1, respectively. Such difference was significant statistically (p=0.035). According to our analysis, the differences in kimchi cabbage productions resulted from low temperature, short sunshine duration, and precipitation increase during the cultivation period of highland kimchi cabbage. This study may help for further analysis on the impact of extreme weather conditions during El Niño years on crop production.

• Korean Journal of Environmental Agriculture
• /
• v.40 no.4
• /
• pp.313-321
• /
• 2021

BACKGROUND: Ammonia is a causative substance for the fine particulate matters (PM_2.5) and generates dust through atmospheric reactions. Agricultural sector accounts for 79.3% of ammonia emissions in Korea. Urea and composted organic fertilizer (COF) are used in the soil for the purpose of supplying nutrients in grapevine orchards. This study was conducted to investigate estimates of ammonia emission and examine fruit quality from the rain proof cultivation of the 'Beni Balad', applied by urea and COF to the soil. METHODS AND RESULTS: Urea, COF1, and COF2 were applied at the rates of 119, 135, and 271 kg ha^-1 respectively. Ammonia emissionwas measured using a dynamic flow-through method. CONCLUSION(S): Ammonia emissions by urea and COF treatments to 'Beni Balad' soils under rain proof cultivation were calculated to be 2.63, 12.95, 2.05, and 3.97 kg NH₃-N ha^-1 day^-1, respectively for the control, urea, COF1, and COF2. Urea soil application increased soluble solids, firmness, and anthocyanin content in fruits at harvest, and COF1 application increased the soluble solids and anthocyanin content. For all the treatments, acidity increased in the harvested fruits.

• 한국노년학
• /
• v.31 no.2
• /
• pp.211-222
• /
• 2011

The purpose of this study was to assess pain, life satisfaction, sleep pattern, and depression and the relations between these in elderly women with ostearthritis. Methods: The subjects were 124 elderly women with osteoarthritis at senior center in C city. Data were analyzed by descriptive statistics, Pearson's correlation coefficients, and multiple regression with SPSS/WIN 14.0. Results: The major findings of this study were as follows. 1) The mean score of variables were pain 2.58, life satisfaction 65.4, sleep pattern 37.6 and depression 13.58. 2) 43.5% of the subjects belonged to depression group. 3) There were significant relationships between depression and pain, life satisfaction, sleep pattern. 4) Significant factors influencing depression were life satisfaction, pain and sleep pattern. These factors explained 48% of depression in elderly women with ostearthritis. Among them, life satisfaction was the most significant factor. Conclusion: These finding give useful information for constructing an intervention and preventive program depression in the elderly women with osteoarthrtitis.

• Journal of The Korean Society of Integrative Medicine
• /
• v.12 no.2
• /
• pp.133-140
• /
• 2024

Purpose : People who have suffered from COVID-19 suffer from decreased pulmonary function and various side effects. This study aims to present three respiratory exercise intervention methods to improve pulmonary function in COVID-19 survivors. Therefore, the purpose of this study will investigate the effects of breathing exercise interventions (aerobic exercise, diaphragm breathe exercise, and inspiratory muscle training on resistance) on pulmonary function in COVID-19 survivors. Methods : The subjects who participated in this study were 35 male and female college students confirmed with COVID-19. All subjects were randomly assigned to A, D, and I groups according to breathing exercise intervention method. Groups A, D, and I each performed aerobic exercise, diaphragm breathing exercise, and inspiratory muscle training on resistance, 3 times a week for 6 weeks. Pulmonary function was measured using a spirometer, and FVC (forced vital capacity), FEV₁ (forced expiratory volume in one second), FEV₁/FVC % (forced expiratory volume in one second / forced vital capacity ratio), and PEF (peak expiratory flow) were measured at 0, 3, and 6 weeks. Data analysis was compared by repeated measures analysis of variance, and post hoc tests for time were compared and analyzed using paired t-tests. Results : In the results of this study, FVC values showed statistically significant improvement in all groups. FEV₁ values also showed statistically significant improvement in all groups. And the FEV₁/FVC % value also showed statistically significant improvement in all groups. And the PEF values also showed statistically significant improvement in all groups. Conclusion : The results of this study reported that aerobic exercise, diaphragm breathing exercise, and resistance inspiratory muscle training were all effective in improving pulmonary function in COVID-19 survivors. Therefore, application of the three breathing exercise intervention methods presented in this study will help improve pulmonary function in COVID-19 survivors.

• Research in Community and Public Health Nursing
• /
• v.14 no.4
• /
• pp.568-578
• /
• 2003

This study was conducted to estimate the effects of self-care program on knowledge and symptoms related hypertension self-care and physiological index in essential hypertensive patients aged between 35-74 year. The subjects for the experiment group and the control group of this study were 70 men and women selected through random sampling from adults at Sangju Red Cross Hospital in Gyeongsanbuk-do, and the experiment was carried out during the period from the 15th of September to the 30th of April in 2002. This study measured systolic and diastolic blood pressure (SBP, DBP, the mean value of the two measures) and total cholesterol (TC) and surveyed the subjects' diet and life style in relation to hypertension using a self-report questionnaire. In order to study the significance of the effects of self-care program, the author carried out t-test, paired t-test, ANCOVA, chi-square analysis and effectiveness index (EI) analysis. Results of the study are as follows: The experiment group got higher mean scores than the control group in the degree of low sodium intake and the degree of high calcium and high potassium intake, and the difference was statistically significant(P<0.05). The effectiveness index of the self-care program in smoking was 0.797 at the 1st posttest and 0.601 at the 2nd posttest, and in physical activities 0.600 at the 1st posttest and 0.849 at the 2nd posttest. The rate of regular antihypertensive drugs intake of the experimental group was higher than that of the control group. and the effectiveness index of the self-care program was 0.715. The mean score of the systolic blood pressure of the experimental group was lower than that of the control group, and the difference was statistically significant(P<0.05). In conclusion, these findings support usefulness of self-care programs in reducing systolic blood pressure and in promoting self-care related to diet and life style for treating and preventing hypertension.

• Korean Journal of Oriental Medicine
• /
• v.6 no.1
• /
• pp.29-46
• /
• 2000

The clinical application of constitutional Diagnosis is the most important part of Sasang constitutional medicine. It has been studied in various way. The study of morphologic characteristics on the head and face has been identified but didn't considered the Variations of age and sex. For the statistic analysis of the correlation between the sasang constitution and the shape of the face, the head-facial part of 182 cases(the group of throughout the age) and 69 cases(the group of age 30 to 40) were measured by Martin's measurement and analysis of a) the measurement value of height and the component ratio from the Gnathion to each part of face by constitution. b) the measurement value of depth and the component ratio from T-projected to each part of the face by constitution. c) the measurement value of breadth and component ratio between each parts of the facial breadth by constitution. d) the characteristics on each part of face by constitution. e) the result of discriminant analysis about the constitution Authors obtained the results from the study as follows: 1. Taeum-In group is characterized by the value of variables had a tendency to maximum value in throughout the age, the charateristics that the total group show is the shape of face is wide shape in horizontally and flat, the nasal breadth is wider than other constitutions, the lips is narrower than Soyang-In in horizontally and thick shape in vertically, and the biogonial breadth is more developed than other constitutions, so lower face is developed. The charateristics that only the age of 30 40 group show is that the lips is thicker than Soeum-IN. The projection of inter-eyebrows is more projected than Soyang-IN. 2. Soeum-IN group is characterized by the value of variables had a tendency to minimum value in throughout the age. The characteristics that the total group show is the lips is thiner than other constitutions, the breadth of eyes is wider than other constitutions, the difference between sellion and nasal breadth is to be little. The charateristics that only the age of 30 40 group show is that the ratio of upper face in physiognomic face is lager than Soyang-IN. 3. The total age group of Soyang-In is characterized by the shape of face is long in vertically and narrow in horizontally, the total eyebrow breadth and lips and philtrun is wider than other constitutions. The charateristics that only the age of 30 40 group is characterized by the projection of sellion is more projected than Taeum-IN. 4. The values which showed significance in both age group V76, V52, V54, V55, V57, V59, V64, V65, V67, V88, V89, V148, V150, V151, V155, V160, V161, V28, V50, V99, V102, V167, V169, V173, V175, V177, V181 are 27 in all. 5. The values which was significant in the age 30 to 40 group V77, V78, V79, V109, V140, V142, V143, V166, V174 are 9 in all.

• Journal of agricultural medicine and community health
• /
• v.19 no.2
• /
• pp.129-140
• /
• 1994

The survey has for its object to detect prevalence rate of hypertension in target population, to find out the risk factor to hypertension, to detect the hypertensive patients cared pattern and therefore, to consider a effective counter plan for the long term about hypertension. The study, population of this survey was 894 out of 1013 target population from Feb. 1 1994 to March 31 1994 in Kyougsang-namdo Ulsan-gun Samnam-myoun. For these two month, check of blood pressure and direct measurement of height and weight was carried out by mass screening and home visiting and had an interview about risk factors for hypertension and cared pattern by questionnaire. The results of survey were as follows : 1. The prevalence rate of 894 study, population was 27.5% and 26.0% in man and 28.6% in women. 2. In male, the prevalence rate for age group, family history of hypertension, drinking, salt intake by risk factors were significant statistically. 3. In female, the prevalence rate for salt intake, body mass index by risk factors were significant statistically. 4. Motivation which was diagnosed as hypertension was that be examined for subjective symptoms of hypertension and routine check for health was only 25.0%, 9.1% and visiting to the hospital for other diseases, detect hypertension by chance was 65.9%. 5. The experience of treatment in prevalent cases was significant statistically in middle class of SES. And the place of treatment by risk factors could not be significant statistically in spite of the majority selected hospital generally. 6. The reasons of non-compliance in prevalent cases was restricting daily activities for its 45.5% most high and the interruption of treatment in prevalent cases was far from hospital geographically for its 47.6% most high 7. The preventive behavior about hypertensive by risk factors or general characteristics wasn't significant statistically. 8. Being treated or not in the near future about age group, SES, family history of the hypertension was significant statistically. And with regard to the place of treatment in the near future, in spite of the majority selected hospital generally, it wasn't significant statistically. 9. The reasons of non-compliance in incidence cases was restricting daily activities for its 46.8% most high. 10. The preventive behavior in the near future about age group, education level, SES, family history of hypertension was significant statistically.

• Journal of Distribution Research
• /
• v.16 no.1
• /
• pp.117-140
• /
• 2011

The sales promotion strategy can be classified into two categories: cost-down and value-added promotions. Although many studies have been performed on sales promotion in the past, little attention has been given on cost-down promotion, and in particular on its strategy. Also there has been a renewed interest on value-added promotion strategy as means of attracting more customers and delivering value by providing a greater benefit. This study examines the effect of value-added promotion on the evaluation of promotional products. The topic is important because the value-added promotions are not always perceived as a benefit by consumers and they depend on the situational factors. We postulate three hypotheses on the basis of related literature. We conduct two studies: one employing experiment (study 1) and the other, quasi-experiment (study 2) to investigate the effect of two situational factors, namely the promotional package type and retailer uncertainty on the valuation of promotional products. Study 1 employs 2 promotional package types (bundled with freebie type vs. one-plus-one type) by 3 evaluation targets (overall package, a focal product and freebie) in experimental design. Also it is found that consumers devaluate the promotional product when the level of retailer uncertainty is high (t=-4.70, p=.000) as shown in Table 2. As depicted in Figure 2, the interaction effect of retailer uncertainty and package types on the evaluation of promotional product as a whole does not appear to be significant. However, when the level of retailer uncertainty is high, the focal product suffers from lower valuation if it is included in a bundle with freebie type package. The purpose of Study 2 is to cross-check the results of Study 1. The results of Study 2 also show that the consumers devaluate the promotional products as a whole when the level of retailer uncertainty is high. Furthermore, Study2 examines the consumers' willingness to purchase. The willingness to purchase of 2 different consumer groups divided by their reservation prices before and after exposure to a promotional stimuli shows no significant differences(t=1.911, p=.057). The results suggest that the consumers' reservation prices before the exposure to the promotion can be a reference prices of their's. But after the promotional events, the promotional price would become their reference prices. Furthermore, when the level of retailer uncertainty is high, consumers devaluate the promotional product as a whole. Because the promotional offerings activate the persuasion knowledge of consumers and make them incorporate negative inference about the firm's motives into their valuation and consequently, consumers tend to hesitate to purchase.

• Korean Journal of Poultry Science
• /
• v.38 no.1
• /
• pp.21-28
• /
• 2011

This study was conducted to investigate the effect of dietary supplement of Alisma canaliculatum and Viscum album on the growth performance and immune response of broiler chickens. One hundred and forty Ross broiler chicks (1 day old) were assigned to 4 treatments in 5 replications with 7 birds per replication. The dietary treatments were NC group (without antibiotics), PC group (basal + 50 ppm Oxytetracycline), AC group (basal + Alisma canaliculatum 0.5%), and VA group (basal + Viscum album 0.5%). The results revealed that body weight gain and feed intake were not significantly different among the treatments. Addition of AC to the diet showed significantly higher feed conversion ratios than the VA addition diet and other treatments (p<0.05). The concentration of linolenic acid, ${\alpha}$-linolenic acid and arachidonic acid in the AC and VA treatment were relatively higher than that in the antibiotic treatment, while there was no difference in the concentration of SFA, USFA, and USFA/SFA. The serum IgG concentration in chickens tended to increase in the AC and VA treatment groups compared to NC group. The IL2 concentration in AC and VA groups was significantly higher than in other group (p<0.05). IL6 was not detected, however. GOT, GPT, and T-billirubin in the VA group were significantly higher than in other groups (p<0.05). Thus, the VA additives can result in the damage of liver and kidney. In conclusion, the dietary supplement of a 0.5% of AC and VA showed a similar growth performance and increased immunity response comparable to supplementing a 50 ppm Oxytetracycline. Therefore, it can be said that the AC and VA are possible alternates of antibiotics.