• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2003.05a
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• pp.177-177
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• 2003

Adult periodontitis is a chronic inflammatory disease whose etiology is not well defined. Recent studies have shown that vitamin D receptor gene has been a candidate for the susceptibility of adult periodontitis. The purpose of this study is to investigate the frequency of Taq I restriction fragment length polymorphism (RELP) in the vitamin D receptor gene in 141 periodontically healthy controls and 32 adult periodontitis patients. Taq I RFLP in the vitamin D receptor gene were detected by PCR amplification, followed by restriction enzyme digestion and 2% agarose gel electrophoresis. There were no significant difference in the distribution of Taq I RFLP between healthy controls and adult periodontitis group (P > 0.05). Thus, Taq I RFLP in the vitamin D receptor gene may not confer the susceptibility to adult periodontitis in Korean population. However, t allele distributions of this RFLP showed various frequencies among ethnic groups studied. Further studies in other ethnic groups will be required.

• Proceedings of the KSPS conference
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• 2000.07a
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• pp.365-365
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• 2000

English segments adopted into Korean can be divided into three types: Some English segments /$m, {\;}n, {\;}{\eta}, {\;}p^h, {\;}t^h, {\;}k^h$/ are adopted into the original sound [$m, {\;}n, {\;}{\eta}, {\;}p^h, {\;}t^h, {\;}k^h$] in Korean. Other segments /b, d, g/ appear in the voiceless stop form [p, t, k]. Generative Phonology explains the presence of the above English segments in Korean but it cannot explain why the English segments /$f, {\;}v, {\;}{\Theta}, {\;}{\breve{z}}, {\;}{\breve{c}}, {\;}{\breve{j}}$/ disappear during the adopting process. I present a set of universal constraints from the Optimality Theory proposed by Prince and Smolensky(l993) and I show how English segments differently adopted into Korean can be explained by these universal constraints such as Faith(feature). N oAffricateStop, Faith(nasal), NoNasalStop, Faith(voice), NoVoicedStop and the interaction of these constraints. I conclude that this Optimality Theory provides insights that better capture the nature of the phonological phenomena of English segments in Korean.

• Bulletin of the Korean Mathematical Society
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• v.38 no.2
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• pp.223-230
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• 2001

In this parper, we considered the uniqueness of positive time-solution to equation ${\Box}_g$u(t,$\chi$) - $c_n$u(t,$\chi$) + $c_n$u(t,$\chi$)$^[\frac{n+3}{n-3}]$ = 0, where $c_n$ = $\frac{n-1}{4n}$ and ${\Box}_g$ is the d'Alembertian for a Lorentzian warped manifold M = {a,$\infty$] $\times_f$ N.

• Kyungpook Mathematical Journal
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• v.52 no.1
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• pp.33-38
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• 2012

The purpose of the present paper is to investigate mapping properties of an integral operator in which we show that the function g defined by $$g(z)=\{\frac{c+{\alpha}}{z^c}{\int}_{o}^{z}t^{c-1}(D^nf)^{\alpha}(t)dt\}^{1/{\alpha}}$$. belongs to the class $S(A,B)$ if $f{\in}S(n,A,B)$.

• Korean Journal of Human Ecology
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• v.22 no.6
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• pp.615-631
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• 2013

In this study, we attempt to explore various possible types of unmarried single women. Main purpose of the work is to find out possible types of unmarried single women in terms of their subjective views on single life based on Q methodology. Q methodology is a research method to study and understand people's "subjectivity" or their points of view. Here, we applied Q methodology to unmarried single women's subjective evaluation of their own lives. Thirty-one Q-questions were prepared through literature review, and were offered to eighteen unmarried single women. As a result, the subjects could be classified into the following five different types: (Type 1) 'I love my work but I hate pressure (for marriage) from others', (Type 2) 'I feel anxiety and stress (on marriage) but I am still waiting for a true love of mine', (Type 3) 'My life is most important and I'd rather enjoy my single life without restraint from others', (Type 4) 'I am weary of continuing my single life, and now I really want to get married and form a family', (Type 5) 'I don't feel comfortable with dating, marriage life etc, I'd rather continue my single life with less stress'.

• Journal of Oriental Neuropsychiatry
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• v.11 no.2
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• pp.87-102
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• 2000

Depression is a psychiatric syndrom consisting of dejected mood, psychomotor retardation, insomnia and weight loss. sometimes associated with irrational quilt feeling. And it is also similiar to Hwa-byung(火病) symptom in oriental medicine. But it is difficult to diagnose with objective method. Digital Infrared Thermographic Imaging(D.I.T.I.) is one of diagnotic method that measure the changes of skin temperature in body.Specially we checked the skin temperature on depressed patients by using D.I.T.I. and compared with Bell's palsy patients and normal persons group.The results are as follows:Average body temperature of the depressed patient group is 36.62${\cdot}$0.58$^{\circ}C$ , Bell's palsy patients group is 36.59${\cdot}$0.34$^{\circ}C$ and that of the control group is 36.71${\cdot}$0.43$^{\circ}C$ . So there is no meaningful difference. The depressed patient group has higher temperature than the Bell's palsy patients group and control group by $\delta$T〉1.0$^{\circ}C$ at the following acupuncture points in these body parts - upper and lower, left and right, anterior and posterior. When acupuncture points temperature was compared superior and inferior part of the body, depressed patient group have meaningful difference at the GV-4 (Myung-moon) and also in the Bell's palsy patients group and control group.When acupuncture points temperature was compared left and right part of the body. ddpressed patient group have no meaningful difference and also in the Bell's palsy patients group and control group.When acupuncture points temperature was compared in the anterior and posterior part of the body, depressed patient group have meaningful difference at the Gv-4(Myung-moon) and also in the bell's palsy patients group and control group.From this study. we think that D.I.T.I. could be used to diagnose objectively on the depressed patients and useful to another psychoneurogenic diagnosis in oriental medicine.

• Journal of Animal Science and Technology
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• v.58 no.4
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• pp.15.1-15.6
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• 2016

Background: Our previous study had identified the SNP (g.81966377T > C) and indel (g.81966364D > I) located in the promoter of APM1 to have a significant effect on marbling in Hanwoo. APM1 encodes an adipocytokine called adiponectin, which plays a significant role in lipogenesis. The aim of this study was to verify and validate the effect of the SNP and indel on marbling and other carcass traits in a large, representative, countrywide population of Hanwoo cattle. The carcass traits measured were marbling (MAR), backfat thickness (BFT), loin eye area (LEA), and carcass weight (CAW). Results: Primers were designed to amplify 346 bp of the genomic segment that contained the targeted SNP (g.81966377) and the indel (g.81966364). After data curation, the genotypes of 8,378 individuals identified using direct sequencing analysis estimated frequencies for C (0.686) and T (0.314) respectively showing genotype frequencies for CC (0.470), CT (0.430) and TT (0.098). The genotypes were significantly associated with MAR, BFT and LEA. The indel had significant effect on marbling (P < .0001) with strong additive genetic effects. The allele frequencies was estimated at (DEL, 0.864) and insertion (INS, 0.136) presenting genotypes of D/D (75.63 %), D/I (21.44 %), and I/I (2.92 %). Significant departure from Hardy-Weinberg equilibrium was not detected for both the SNP and the indel. Conclusion: The SNP genotypes showed significant association with MAR, BFT and LEA with strong additive genetic effects, while the indel was significantly associated with MAR. The results confirmed that the variants can be used as a genetic marker for improving marbling in Hanwoo.

• Journal of the Korean Society of Clothing and Textiles
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• v.25 no.5
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• pp.925-932
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• 2001

The influence of ultraviolet(UV)-ray in sun light on human skin has been noted. Textiles can provide protection against harmful UV-radiation. Normally UV-absorbing finishes are used to get better protection. The purpose of this study is to evaluate the UV-cut properties of cotton fabrics treated with UV-absorber. 2,2-dihydroxy-4,4-dimethoxbenzophenone, as UV-absorber was applied to 100% cotton fabric. Reagents added in finishing solution were Triton X-100, polyethylene glycol 400, and $MgCl_2{\cdot}6H_2O$, and C.I. Direct Red 81. Both untreated and treated cotton fabrics were exposed to a xenon arc lamp for 20 and 80 hours. UV absorption spectra of finishing solutions and UV transmission spectra of fabrics were measured by the UV/VIS spectrophotometer. The results of this study can be summarized as follows. The results of this study can be summarized as follows. Absorption and the related transmission spectra were modified in a controlled way with UV-absorber. Absorption effect of UV-absorber was improved by adding Triton X-100, PEG 400, and $MgCl_2{\cdot}6H_2O$ in finishing solution. The UV absorption of finishing solution was in the following order: U/D/T/P/M>D/T/P/M> D/T> D/P, D>U/T/P/M>U/T>T/P/M>T. The UV transmittance of cotton fabrics was remarkably decreased by the application of UV-absorber and additives. The UV-cut properties were most improved by the application of U/D/T/P/M.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9667-9672
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• 2014

Background: Pancreatic adenocarcinoma is a malignant gastrointestinal cancer with significant morbidity and mortality. Despite severe side effects of chemotherapy, the use of immunotherapy combined with chemotherapy has emerged as a common clinical treatment. In this study, we investigated the efficacy of the combined doxorubicin and interferon-${\alpha}$ (IFN-${\alpha}$) therapy on murine pancreatic cancer Panc02 cells in vitro and in vivo and underlying mechanisms. Materials and Methods: A Panc02-bearing mouse model was established to determine whether doxorubicin and interferon-${\alpha}$ (IFN-${\alpha}$) could effectively inhibit tumor growth in vivo. Cytotoxicity of natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) was evaluated using a standard LDH release assay. To evaluate the relevance of NK cells and CD8 T cells to the combination therapy-mediated anti-tumor effects, they were depleted in tumor-bearing mice by injecting anti-asialo-GM-1 antibodies or anti-CD8 antibodies, respectively. Finally, the influence of doxorubicin+interferon-${\alpha}$ (IFN-${\alpha}$) on the ligands of NK and T cells was assessed by flow cytometry. Results: The combination therapy group demonstrated a significant inhibition of growth of Panc02 in vivo, resulting from activated cytotoxicity of NK cells and CTLs. Depleting CD8 T cells or NK cells reduced the anticancer effects mediated by immunochemotherapy. Furthermore, the doxorubicin+IFN-a treatment increased the expression of major histocompatibility complex class I (MHC I) and NKG2D ligands on Panc02 cells, suggesting that the combined therapy may be a potential strategy for enhancing immunogenicity of tumors. All these data indicate that the combination therapy using doxorubicin and interferon-${\alpha}$ (IFN-${\alpha}$) may be a potential strategy for treating pancreatic adenocarcinoma.

• Journal of the Korean Institute of Telematics and Electronics T
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• v.35T no.2
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• pp.6-12
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• 1998

Thin film SOI(Silicon-on-insulator) device offer unique advantages such as reduction in short channel effects, improvement of subthreshold slope, higher mobility, latch-up free nature, and so on. But these devices exhibit floating-body effet such as current kink which inhibits the proper device operation. In this paper, the SOI NMOSFET with a T-type gate structure is proposed to solve the above problem. To simulate the proposed device with TSUPREM-4, the part of gate oxide was considered to be 30nm thicker than the normal gate oxide. The I-V characteristics were simulated with 2D MEDICI. Since part of gate oxide has different oxide thickness, the gate electric field strength is not same throughout the gate and hence the impact ionization current is reduced. The current kink effect will be reduced as the impact ionization current drop. The reduction of current kink effect for the proposed device structure were shown using MEDICI by the simulation of impact ionization current, I-V characteristics, and hole current distribution.