• The Korean Journal of Physiology and Pharmacology
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• v.17 no.2
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• pp.163-167
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• 2013

In the present study, the effect of intrathecal (i.t.) or intracerebroventricular (i.c.v.) administration with cholera toxin (CTX) on the blood glucose level was examined in ICR mice. The i.t. treatment with CTX alone for 24 h dose-dependently increased the blood glucose level. However, i.c.v. treatment with CTX for 24 h did not affect the blood glucose level. When mice were orally fed with D-glucose (2 g/kg), the blood glucose level reached to a maximum level at 30 min and almost returned to the control level at 120 min after D-glucose feeding. I.c.v. pretreatment with CTX increased the blood glucose level in a potentiative manner, whereas i.t. pretreatment with CTX increased the blood glucose level in an additive manner in a D-glucose fed group. In addition, the blood glucose level was increased in formalin-induced pain animal model. I.c.v. pretreatment with CTX enhanced the blood glucose level in a potentiative manner in formalin-induced pain animal model. On the other hand, i.t. pretreatment with CTX increased the blood glucose level in an additive manner in formalin-induced pain animal model. Our results suggest that CTX administered supraspinally or spinally differentially modulates the regulation of the blood glucose level in D-glucose fed model as well as in formalin-induced pain model.

• IMMUNE NETWORK
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• v.11 no.6
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• pp.406-411
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• 2011

Background: Invariant Natural killer T (iNKT) cells, a distinct subset of CD1d-restricted T cells with invariant $V{\alpha}{\beta}$ TCR, functionally bridge innate and adaptive immunity. While iNKT cells share features with conventional T cells in some functional aspects, they simultaneously produce large amount of Th1 and Th2 cytokines upon T-cell receptor (TCR) ligation. However, gene expression pattern in two types of cells has not been well characterized. Methods: we performed comparative microarray analyses of gene expression in murine iNKT cells and conventional $CD4^+CD25^-$ ${\gamma}{\delta}TCR^-$ T cells by using Gene Set Enrichment Analysis (GSEA) method. Results: Here, we describe profound differences in gene expression pattern between iNKT cells and conventional $CD4^+CD25^-$ ${\gamma}{\delta}TCR^-$ T cells. Conclusion: Our results provide new insights into the functional competence of iNKT cells and a better understanding of their various roles during immune responses.

• Journal of Oral Medicine and Pain
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• v.10 no.1
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• pp.17-31
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• 1985

Personality characteristics of TMJ dysfunction patients was studied by means of MMPI test. 100 TMJ dysfunction patients and 100 healthy controls were subjected at the Department of Oral Diagnosis and Oral Medicine, Pusan National University Hospital, during the period from March 1983 to February 1985. All the patients were divided into 2 groups namely, acute group and chronic group by duration of path and discomfort problems for 6 months or longer. The obtained results were as follows : 1. Mean value of T-scores on each clinical scale was within normal range in both patient and control group. 2. There was significant difference in scales of Hs, D. Hy, Pt, Sc and IR between patient and control group. 3. As compared with control group by sexual subclass, scales of Hs, Hy and Pt of both sex, scales of Sc and M-DI of male and scales of D of female in patient group were significantly higher than those in control group 4. The longer was duration of TMJ problems, i.e., in increasing order of control, acute and chronic group, the higher was mean value of T-scores on scales of Hs, D, Hy, Pt, Sc, IR and M-DI. 5. Mean values of T-scores on scales of Hs, D and Hy were the highest in all the clinical scales of total class and subclasses(i. e. male group, female group, acute group and chronic group) with TMJ dysfunction and showed 1-:i-2 (Hs, -Hy, -D. ) profile pattern, conversion "V.ot;V.

• Journal of the Korean Statistical Society
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• v.32 no.3
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• pp.311-311
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• 2003

This paper contains the following errors. 1. "$I_{\{x>D\}}{\lambda}dt_{p0}(t)s(x)$" should be added to the right hand side of (2.3). 2. "$I_{\{x>D\}}{\lambda}_{p0}(t)s(x)$" should be added to the right hand side of (2.6). 3. "$I_{\{x>D\}}{\lambda}_{p0}s(x)$" should be added to the right hand side of (2.9). 4. In Theorem 2.3 and its proof, "${\lambda}{\int}_{0}^{D}f(y)s(x-y)dy$" appears three times (including one in (2.20)). To each of these, "${\lambda}_{po}s(x)$" should be added. 5. In Remark 2.5, "${\lambda}dt_{p0}/s(x)dx" should be added to "${\int}_{0}^{D}{\lambda}dt\;s(x-y)dxf(y)dy$". As a result of these corrections, a simpler proof of Theorem 2.3 becomes available. Substituting (2.18), (2.21), (2.22) into the left hand side of (2.20) and comparing the result with (2.10), we have the right hand side of (2.20).

• Computers and Concrete
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• v.5 no.4
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• pp.401-416
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• 2008

The paper presents a methodology to model three-dimensional reinforced concrete members by means of embedded discontinuity elements based on the Continuum Strong Discontinuous Approach (CSDA). Mixture theory concepts are used to model reinforced concrete as a 3D composite material constituted of concrete with long fibers (rebars) bundles oriented in different directions embedded in it. The effects of the rebars are modeled by phenomenological constitutive models devised to reproduce the axial non-linear behavior, as well as the bond-slip and dowel action. The paper presents the constitutive models assumed for the components and the compatibility conditions chosen to constitute the composite. Numerical analyses of existing experimental reinforced concrete members are presented, illustrating the applicability of the proposed methodology.

• Communications of the Korean Mathematical Society
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• v.20 no.1
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• pp.15-21
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• 2005

Null designs on the poset of dual polar spaces are considered. A poset of dual polar spaces is the set of isotropic subspaces of a finite vector space equipped with a nondegenerate bilinear form, ordered by inclusion. We show that the minimum number of isotropic subspaces to construct a nonzero null t-design is ${\prod}^{t}_{i=0}(1+q^{i})$ for the types $B_N,\;D_N$, whereas for the case of type $C_N$, more isotropic subspaces are needed.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.35D no.12
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• pp.48-52
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• 1998

We fabricated the newly proposed nano structure memory with SOI edge channel and a nano dot. The width of the edge channel of this device, which uses the side wall as a channel and has a nano dot on this channel region, was determined by the thickness of the recessed top-silicon layer of SOI wafer. The size of side-wall nano dot was determined by the RIE etch and E-Beam lithography. The I$_{d}$-V$_{d}$, I$_{d}$-V$_{g}$ characteristics of the devices without nano dots and memory characteristics of the devices with nano dots were obtained, where the voltage scan was done between -20 V and 14 V and the threshold voltage shift was about 1 V.t 1 V.

• Journal of Digital Convergence
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• v.14 no.11
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• pp.333-345
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• 2016

This study was to determine the relationship between nurse DISC personality types, self-efficacy, clinical performance. Data were collected from 302 nurses in 5 hospitals in K city. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient. With regard to self-efficacy and clinical performance, D type showed a higher score than type I type and S type. The lower region of the clinical performance showed the nursing process, nursing skills, higher score than the D Type S Type in professional development. With regard to personality and self-efficacy, and clinical performance, the type D (r=.56, p<.01), I type (r=.66, p<.01), S type (r=.6, p<.01) showed a positive correlation with type C (r=.52, p<.01). As shown by these results, each personality type has a different correlation with self-efficacy and clinical performance ability. This factor should be considered in the assignment of nurses to departments or individual training programs so that they can deliver the most effective job performance.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.20 no.9
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• pp.2981-2990
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• 1996

Dual solutions for steady natural convection of air between two horizontal concentric cylinders are numerically investigated in the range of $D_i$/TEX>/L(=diameter of inner cylinder/gap width)$\leq$10. It is found that, when the Rayleigh number based on the gap width exceeds a certain critical value, a new flow pattern forming two counter-rotating eddies in the half of the annulus can be realized, which is different from the crescent-shaped flow commonly observed. In the new flow pattern, the fluid near the top of the hot inner cylinder moves downward. This solution is found for D$_{i}$/L.geq.0.3, but not for$D_i$/TEX>/L$\leq$0.2. As $D_i$/TEX>/L increase, the critical Rayleigh number is decreased, and tends to a finite limit.t.

• Bulletin of the Korean Chemical Society
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• v.17 no.11
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• pp.1031-1036
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• 1996

The synthesis and characterization of diastereomeric dodecanucleotides, d[GATCp(S)TCGAGATC], containing recognition sequence of the XhoI restriction endonuclease with a phosphorothioate internucleotidic linkage the cleavage site are described. Rp and Sp form of diastereomerically pure dinucleoside phosphorothioates d[Cp(S)T] were presynthesized and used for the addition to the growing oligonucleotide chain as a block. The stereochemistry of dinucleoside phosphorothioate was assigned by 31P NMR spectroscopy, enzyme digestion, and reverse-phase HPLC. XhoI restriction endonuclease cut only Rp diastereomer d[GATCp(S))TCGAGATC]. The rate of hydrolysis is slower than that of the unmodified dodecamer d[GATCTCGAGATC]. The phosphorothioate nucleotide is using for determination of the stereochemical course of the XhoI catalyzed reaction.