• Journal of Periodontal and Implant Science
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• v.38 no.sup2
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• pp.299-308
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• 2008

Purpose: The aim of this study was to evaluate adhesion and gene expression of the MC3T3-E1 cells cultured on machined titanium surface (MS) and anodized titanium surface (AS) using MTT test, Scanning electron micrograph and cDNA microarray. Materials and Methods: The MTT test assay was used for examining the proliferation of MC3T3-E1 cells, osteoblast like cells from Rat calvaria, on MS and AS for 24 hours and 48 hours. Cell cultures were incubated for 24 hours to evaluate the influence of the substrate geometry on both surfaces using a Scanning Electron Micrograph (SEM). The cDNA microarray Agilent Rat 22K chip was used to monitor expressions of genes. Results: After 24 hours of adhesion, the cell density on AS was higher than MS (p < 0.05). After 48 hours the cell density on both titanium surfaces were similar (p > 0.05). AS had the irregular, rough and porous surface texture. After 48 hours incubation of the MC3T3-E1 cells, connective tissue growth factor (CTGF) was up-regulated on AS than MS (more than 2 fold) and the insulin-like growth factor 1 receptor was down-regulated (more than 2 fold) on AS than MS. Conclusion: Microarray assay at 48 hours after culturing the cells on both surfaces revealed that osteoinductive molecules appeared more prominent on AS, whereas the adhesion molecules on the biomaterial were higher on MS than AS, which will affect the phenotype of the plated cells depending on the surface morphology.

• YAKHAK HOEJI
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• v.46 no.4
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• pp.290-294
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• 2002

Cephradine is an orally absorbed cephalosporin with a broad spectrum of activity against gram-positive and gram-negative bacteria and is highly resistant to beta-lactamase degradation. The purpose of the present study was to evaluate the bioequivalence of two cephradine capules, Cephradine capsule (Donggu Pharmaceutical Co., reference drug) and Cephradine capsule (Shinpoong Pharmaceutical Co., test drug), according to the guidelines of Korea Food and Drug Administration. Twenty-six normal volunteers, 24.6 $\pm$ 3.70 years in age and 62.4 $\pm$ 8.99 kg in body weight, were divided into two groups and a randomized 2 $\times$ 2 cross-over study was employed. After one capsule containing 250 mg of cephrdine was orally administered, blood was taken at predetermined time intervals and the concentrations of cephrdine in serum were determined using HPLC with UV detector. The pharmacokinetic parameters such as AU $C_{t}$ to $C_{max}$ and $T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in AUCt, $C_{max}$ and $T_{max}$ between two products were 2.89％, 1.05％ and 1.06％, respectively, when calculated against the reference drug. The 90％ confidence intervals were within log0.8 $\leq$ $\delta$ $\leq$ log1.25 (e.g., log0.9803 $\leq$ $\delta$ $\leq$ log1.0734 and log0.9674 $\leq$ $\delta$ $\leq$ log1.220 for AU $C_{t}$, and $C_{max}$, respectively). Two parameters met the criteria of KFDA for bioequivalence, indicating that Cephradine capsules (Shinpoong Pharmaceutical Co.) is bioequivalent to Cephradine capsules (Donggu Pharmaceutical Co.).o.).o.).).o.).

• Journal of the Korean Data and Information Science Society
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• v.21 no.6
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• pp.1101-1108
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• 2010

This study was conducted to investigate whether whole body cryotherapy and spinal decompression have effectiveness on the pain, lumbar flexion range of motion, and global perceived effect scale in patients with lumbar disc herniation. Thirty subjects were participated in this study. And they were all randomly divided into whole body cryotherapy and spinal decompression group. To evaluate the effects of whole body cryotherapy and spinal decompression, subjects were evaluated by using visual analogue scale, lumbar flexion range of motion, and global perceived effect scale. The assessment parameters were evaluated before, after 2 weeks treatments. And we received a consent form whole body cryotherapy subjects. The results of paired t-test, independent t-test, and ANCOVA analysis of variance showed that pain, lumbar flexion range of motion, global perceived effect scale were significantly improved after than before therapy in whole body cryotherapy group. So we conclude that whole body cryotherapy has effectiveness on the pain, lumbar flexion range of motion, and global perceived effect scale in patients with lumbar disc herniation.

• Journal of Haehwa Medicine
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• v.5 no.2
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• pp.485-496
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• 1997

This study explored the relationships between Husband's emotional support and the mother's postpartum depression. The purpose of this study was to contribute to theoretical understanding of the relationships among these two variables and eventually to direct the planning of nursing care that enhance the health status of mothers in the postpartum period. Data were collected from January to June, 1995, with 47 postpartum Korean mothers in NewHampshire state in The United States of America. Postpartum depression was measured by Jung's Self-rating Depression Scale and husband's support was measured by Husband's support scale developed by Cho, Young Sook. Postpartum depression and husband's support were measured by postpartum mothers on the 3rd postpartum day and 2 weeks. The data were analysed by an SPSS computerized program and Percentages, t-test, paired t-test. ANOVA, Pearson correlation coefficients, and Stepwise multiple regression were used. The result of this study were summerized as follows ; 1. Mother's postpartum depression was greater at two weeks than the 3rd day (t=-2.64, p<.05). 2. Mother's percieved husband's supportive behavior was lower at 2 weeks than the 3rd day(t=-3.14,p<.01) 3. The higher the husband's supportive behavior, the lower the postpartum mother's depression (r=-2650,-2845;p<.01) 4. In this study, variables related to the mother's postpartum depression were husband's support, how much the husband liked the baby, occupation, and the knowledge of how to care for the baby. 5. In addition, by using Stepwise multiple regression analysis, it was determined that the main influencing factors on the postpartum depression. The variables - husband's support, how much the husband liked the baby and job made it possible to explain 48.61% of variance in postpartum depression. In conclusion, this study revealed that husband's support is an important factor that decrease the immigrant mother's postpartum depression.

• Journal of Digital Convergence
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• v.16 no.12
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• pp.87-95
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• 2018

The purpose of this study was to validate the effectiveness of academic motivation improvement program for underachieved students. Participants in the program consisted of 14 sophomores and senior. They were randomly assigned to either the experimental group(n=7) or the control group(n=7). To analysis the effectivness, matched pair t-test and independent t-test. The programs offered 6times. The results are follows. First, for the experimental group that took part in motivation improvement program, there was a increase in self-esteem. But the improvement was not significant. Second, for the experimental group that took part in motivation improvement program, there was a significant decrease in academic amotivation. Third, the experimental group showed a more significant decrease in academic amotivation. Finally, the significance and limitations of this study and suggestions for future research were presented.

• Journal of Ginseng Research
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• v.45 no.1
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• pp.191-198
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• 2021

Background: Most clinical studies of immune responses activated by Korean Red Ginseng (KRG) have been conducted exclusively in patients. However, there is still a lack of clinical research on immune-boosting benefits of KRG for healthy persons. This study aims to confirm how KRG boosts the immune system of healthy subjects. Methods: A total of 100 healthy adult subjects were randomly divided into two groups that took either a 2 g KRG tablet or a placebo per day for 8 weeks. The primary efficacy evaluation variables included changes in T cells, B cells, and white blood cells (WBCs) before and after eight weeks of KRG ingestion. Cytokines (TNF-α, INF-γ, IL-2 and IL-4), WBC differential count, and incidence of colds were measured in the secondary efficacy evaluation variables. Safety evaluation variables were used to identify changes in laboratory test results that incorporated adverse reactions, vital signs, hematological tests, blood chemistry tests, and urinalysis. Results: Compared to the placebo group, the KRG intake group showed a significant increase in the number of T cells (CD3) and its subtypes (CD4 and CD8), B cells, and the WBC count before and after eight weeks of the intake. There were no clinically significant adverse reactions or other notable results in the safety evaluation factors observed. Conclusion: This study has proven through its eight-week intake test and subsequent analysis that KRG boosts the immune system through an increase in T cells, B cells, and WBCs, and that it is safe according to the study's safety evaluation.

• Journal of Christian Education in Korea
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• v.76
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• pp.237-258
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• 2023

Purpose of Research: This study examines how an intensive Christian program focused on conversion and sanctification impacts youth spirituality. While previous research was qualitative, looking at program design and family-church ties, this research provides a needed quantitative analysis of the program's effect on youths' spiritual development. Research content and method: The research, centering on 'A' Camp's focus on conversion and sanctification, used a pre-post test model with Lee and Kim's metrics to gauge youth spirituality. Conducted in a 2023 summer camp, assessments on days one and three yielded 109 valid questionnaires, analyzed via paired t-tests. As a result of the analysis, relationship with God t=-9.65, traditional faith t=-6.22, influence of spirituality t=-6.35, religious activity t=-8.32, experience of transcendent power t=-8.67, living righteously t=-8.04 It was statistically significant in all areas. Conclusion and Recommendation: The study confirmed that programs emphasizing conversion and sanctification markedly improve youth spirituality, notably enhancing experiences of God and righteous living via the Holy Spirit. These findings are pivotal for guiding future youth education programs, especially those conducted in camp settings.

• Journal of the Korean Institute of Gas
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• v.14 no.1
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• pp.47-54
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• 2010

In order to reduce the number of installation processes and the cost, a unified ball valve and polyethylene-steel pipe is proposed and tested. An integrated design approach is carried out such that a virtual manufacturing based on finite-element analysis is first performed in order to examine contact conditions under exaggerated temperature variations (${\Delta}T\;=\;60^{\circ}C$ and $-50^{\circ}C$ for summer and winter, respectively). From the final design configuration, it was predicted that the maximum contact pressures are 71 and 8.1 MPa for summer and winter, respectively, at relatively larger contact surface. Based on this observation, a prototype model is fabricated to go through an actual leakage test. The prototype pipe passed a hydrostatic strength test successfully, showing no leakage at even much higher (54 MPa) than the operational pressure (0.25 MPa).

• Science of Emotion and Sensibility
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• v.14 no.3
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• pp.385-394
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• 2011

The purpose of this research is to compare and analyze visual images between the Real garment and the 3D garment simulation with the various fabrics of flare skirts and to analyze the correlation between mechanical properties and visual images. The picture images (printed on paper) of the Real garment and the 3D garment simulation of experimental flare skirts were shown to the evaluation group of women in their 20s majoring in clothing and textiles, and were evaluated by questionnaires with 32 adjectives. SPSS Version 12.0 statistics program was utilized to analyze data. Factor analysis, One Way ANOVA, T-test and Duncan test were used to investigate visual effect of the Real garment and the 3D garment simulation. As the result of conducting factor analysis on the visual appearance, the images were driven with five factors: 'drapeability', 'attractive', 'body compensation', 'bulkiness', 'activeness'. Visual images were significantly related with mechanical properties of various fabrics, and the visual images between 3D garment simulations and real garment differed with various fabrics and their mechanical properties. Visual images of silk and polyester group, cotton, linen and wool group were significantly related with weight and thickness of kinds of fabrics.

• Journal of Korean Home Economics Education Association
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• v.12 no.2
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• pp.1-14
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• 2000

The purposes of this study were to identify the adolescent’s perception to grandparent’s clothing behavior, the effect of grandparent’s clothing behavior on the attitudes toward their grand parents, and the variables related to the adolescent’s attitudes toward their grandparent affecting grandparent’s clothing behavior. The results of this study may provide the foundations for the continuing family educational material to promote the grandparent-grandchildren relationship. Questionnaires were distributed to middle and high school students in Chonbuk Province through school teachers from June 9th 18th. 1999. and 485 questionnaires were analysed. Frequencies percentages, factor analysis. Cronbach’s a. t-test, F-test. and Duncan’s Multiple Range test were used for data analysis. The results were as follows: 1. The adolescent’s perception level of grandparent’s clothing behavior was higher when grandparents were younger. healthier and wealthier. in separate living status. and in case of younger and more female adolescents. In case of separate living status. the adolescent’s perception level was higher when grandparent and adolescent contacted frequently. 2. The adolescent’s perception level of grandparent’s clothing behavior was favorable when their total attitude toward grandparent was positive, especially in economic, intellectual. personality, and family relation aspects. 3. The effects of the perception of grandparent’s clothing behavior on the adolescent attitude toward their grandparent were higher in case of grandmother. female adolescent. and separate living status, less educated. and in worse health status grandparent.