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The Use of Locally Applied Vibration to Minimize Pain during Fractional CO2 Laser Therapy in Living Liver-Donor Scar Management

  • Song, Sinyoung;Choi, Dong Hoon;Oh, Tae Suk
    • Archives of Plastic Surgery
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    • v.43 no.6
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    • pp.570-574
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    • 2016
  • Background Fractional $CO_2$ laser is an effective treatment for scars, but most patients complain about sharp burning pain, even after the application of lidocaine ointment. This study analyzed the impact of a vibrating device to nonpharmacologically reduce the acute pain of laser treatment, in accordance with the gate control theory of pain management. Methods This is a prospective study performed from May 2013 through March 2014. Fifty-three patients (mean age, 26.7 years; range, 16-44 years) who had donated livers for liver transplantation were treated with a fractional $CO_2$ laser (10,600 nm; model $eCO_2$, Lutronic Corp) for their abdomen scars. Laser treatment was applied 4 months after surgery. A commercially available, locally applied vibrating device (model UM-30M, Unix Electronics Co. Ltd.) was used, in an on-and-off pattern, together with the $CO_2$ laser. A visual analogue scale (VAS; 0, no pain; 10, most severe pain) of pain sensation was assessed and statistically analyzed using a paired t-test. Results The average VAS score for pain with the vibrating device was 4.60 and the average VAS score without the vibrating device was 6.11. The average difference between scores was 1.51 (P=0.001). Conclusions A locally applied vibrating device was demonstrated to be effective in reducing pain when treating with a fractional $CO_2$ laser. Vibration treatment could be helpful when treating scars with fractional $CO_2$ laser in pain-sensitive patients, particularly children.

Nano Bio Imaging for NT and BT

  • Moon, DaeWon
    • Proceedings of the Korean Vacuum Society Conference
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    • 2015.08a
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    • pp.51.2-51.2
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    • 2015
  • Understanding interfacial phenomena has been one of the main research issues not only in semiconductors but only in life sciences. I have been trying to meet the atomic scale surface and interface analysis challenges from semiconductor industries and furthermore to extend the application scope to biomedical areas. Optical imaing has been most widely and successfully used for biomedical imaging but complementary ion beam imaging techniques based on mass spectrometry and ion scattering can provide more detailed molecular specific and nanoscale information In this presentation, I will review the 27 years history of medium energy ion scattering (MEIS) development at KRISS and DGIST for nanoanalysis. A electrostatic MEIS system constructed at KRISS after the FOM, Netherland design had been successfully applied for the gate oxide analysis and quantitative surface analysis. Recenlty, we developed time-of-flight (TOF) MEIS system, for the first time in the world. With TOF-MEIS, we reported quantitative compositional profiling with single atomic layer resolution for 0.5~3 nm CdSe/ZnS conjugated QDs and ultra shallow junctions and FINFET's of As implanted Si. With this new TOF-MEIS nano analysis technique, details of nano-structured materials could be measured quantitatively. Progresses in TOF-MEIS analysis in various nano & bio technology will be discussed. For last 10 years, I have been trying to develop multimodal nanobio imaging techniques for cardiovascular and brain tissues. Firstly, in atherosclerotic plaque imaging, using, coherent anti-stokes raman scattering (CARS) and time-of-flight secondary ion mass spectrometry (TOF-SIMS) multimodal analysis showed that increased cholesterol palmitate may contribute to the formation of a necrotic core by increasing cell death. Secondly, surface plasmon resonance imaging ellipsometry (SPRIE) was developed for cell biointerface imaging of cell adhesion, migration, and infiltration dynamics for HUVEC, CASMC, and T cells. Thirdly, we developed an ambient mass spectrometric imaging system for live cells and tissues. Preliminary results on mouse brain hippocampus and hypotahlamus will be presented. In conclusions, multimodal optical and mass spectrometric imaging privides overall structural and morphological information with complementary molecular specific information, which can be a useful methodology for biomedical studies. Future challenges in optical and mass spectrometric imaging for new biomedical applications will be discussed.

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DC and RF Characteristics of AlGaN/InGaN HEMTs Grown by Plasma-Assisted MBE (AlGaN/InGaN HEMTs의 고성능 초고주파 전류 특성)

  • 이종욱
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.8
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    • pp.752-758
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    • 2004
  • This paper reports on the DC and RF characteristics of AlGaN/InGaN/GaN high electron-mobility transistors (HEMTs) grown by molecular beau epitaxy(MBE) on sapphire substrates. The devices with a 0.5 ${\mu}$m gate-length exhibited relatively flat transconductance(g$\_$m/), which results from the enhanced carrier confinement of the InGaN channel. The maximum drain current was 880 mA/mm with a peak g$\_$m/ of 156 mS/mm, an f$\_$T/ of 17.3 GHz, and an f$\_$MAX/ or 28.7 GHz. In addition to promising DC and RF results, pulsed I-V and current-switching measurements showed little dispersion in the unpassivated AlGaN/InGaN HEMTs. These results suggest that the addition of In to the GaN channel improves the electron transport characteristics as well as suppressing current collapse that is related to the surface trap states.

Investigation on the Conservation Environment for the Shelter of Stone Cultural Properties (I)-Focused on the Standing Stone Buddhist Triad in Bae-ri, Gyeongju and Rock-carved Triad Buddha in Seosan (석조문화재 보호각의 보존환경 연구(I)-경주배리석불입상, 서산마애삼존불상을 중심으로)

  • Hong, Jung-Ki;Eom, Doo-Sung;Chung, Young-Jae;Masayuki Morii
    • 보존과학연구
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    • s.26
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    • pp.141-164
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    • 2005
  • Most of the stone cultural properties is exposed to the weathering factor(rain, windetc.), so the shelter is constructed for reduction of its direct effect. But the shelter is indicated some problems that inharmoniousness of the surroundings, in section disturbance for insufficiency of light, the loss about the value of cultural properties and so on. So we have investigated on environmental condition (temperature, relative humidity, wind etc.) at the Standing Stone Buddhist Triad in Bae-ri, Gyeongju and Rock-carved Triad Buddha in Seosan because check the effect of the shelter. As the result, the Standing Stone Buddhist Triad in Bae-ri, Gyeongju is located a pine wood and a lot of bamboo grow naturally in nearing. Environmental difference on inside and outside of the shelter is not found because opened on all sides. But there is so dim for the direction of the sunlight that can't see the Standing Stone Buddhist. The base rock of Rock-carved Triad Buddha in Seosan well develop with crack and break, and the vegetation(trees, moss, lichen etc.) grow naturally in surroundings. Environmental difference on inside and outside of the shelter is found because closed on all sides and opened the front gate only inspection time. Inside of the shelter was too calm(air-velocity not detected) and humid(over 75%RH). Also the surface is occurred the dew(at 2-4 pm) and the efflorescence for effect of the water(rain, dew etc.). Besides the head of the central Buddhist is so dangerous for crack.

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Rigorous Design of 22-nm Node 4-Terminal SOI FinFETs for Reliable Low Standby Power Operation with Semi-empirical Parameters

  • Cho, Seong-Jae;O'uchi, Shinichi;Endo, Kazuhiko;Kim, Sang-Wan;Son, Young-Hwan;Kang, In-Man;Masahara, Meishoku;Harris, James S.Jr;Park, Byung-Gook
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.10 no.4
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    • pp.265-275
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    • 2010
  • In this work, reliable methodology for device design is presented. Based on this method, the underlap length has been optimized for minimizing the gateinduced drain leakage (GIDL) in a 22-nm node 4-terminal (4-T) silicon-on-insulator (SOI) fin-shaped field effect transistor (FinFET) by TCAD simulation. In order to examine the effects of underlap length on GIDL more realistically, doping profile of the source and drain (S/D) junctions, carrier lifetimes, and the parameters for a band-to-band tunneling (BTBT) model have been experimentally extracted from the devices of 90-nm channel length as well as pnjunction test element groups (TEGs). It was confirmed that the underlap length should be near 15 nm to suppress GIDL effectively for reliable low standby power (LSTP) operation.

A Neural Metwork's FPGA Realization using Gate Level Structure (게이트레벨 연산구조를 사용한 신경합의 FPGA구현)

  • Lee, Yun-Koo;Jeong, Hong
    • Journal of Korea Multimedia Society
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    • v.4 no.3
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    • pp.257-269
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    • 2001
  • Because of increasing number of integrated circuit, there is many tries of making chip of neural network and some chip is exit. but this is not prefer because YLSI technology can't support so large hardware. So imitation of whole system of neural network is more prefer. There is common procedure in signal processing as in the neural network and pattern recognition. That is multiplication of large amount of signal and reading LUT. This is identical with some operation of MLP, and need iterative and large amount of calculation, so if we make this part with hardware, overall system's velocity will be improved. So in this paper, we design neutral network, not neuron which can be used to many other fields. We realize this part by following separated bits addition method, and it can be appled in the real time parallel process processing.

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An Unexpected Improvement of the Symptom from Herniated Intervertebral Disc during Trial of Spinal Cord Stimulation for the Post-herpetic Neuralgia -A case report- (대상포진 후 신경통에 시행된 실험적 척수자극술시 예측치 못한 추간판 탈출증 증상의 개선 -증례 보고-)

  • Ahn, Jae-Seok;Han, Seok-Hee;Kim, Tae-Hyeong;Park, Hahck-Soo;Lim, Young-Jin;Lee, Sang-Chul
    • The Korean Journal of Pain
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    • v.14 no.1
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    • pp.110-113
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    • 2001
  • In controlling chronic intractable pains, the current therapeutic methods used are exercise, over the counter medication, cognitive-behavioral therapy, opioid medication, neural blockade, operation, etc., spinal cord stimulation being the last resort. Spinal cord stimulation was initiated when Shearly and others clinically tested the Gate control theory of Melzack and Wall. This had triggered the advancement of theoretic research on the mechanism and hardware necessary and has resulted in an accumulation of clinical experiences. This is known to be effective for treating sympathetic pain, arachnoiditis, failed back pain syndrome, radiculopathy, peripheral vascular disease, phantom limb syndrome, post-herpetic neuralgia, peripheral neuropathy, and angina pectoris. This report describes our experience in experimental spinal cord stimulation in patients with simultaneous post-herpetic neuralgia and herniated intervertebral disc. There wasn't any improvement in the post-herpetic neuralgia but the symptoms of a herniated intervertebral disc was much ameliorated. This was quite an unexpected result. The patient's back pain returned when the stimulation stopped.

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A Ripple Rejection Inherited RPWM for VSI Working with Fluctuating DC Link Voltage

  • Jarin, T.;Subburaj, P.;Bright, Shibu J V
    • Journal of Electrical Engineering and Technology
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    • v.10 no.5
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    • pp.2018-2030
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    • 2015
  • A two stage ac drive configuration consisting of a single-phase line commutated rectifier and a three-phase voltage source inverter (VSI) is very common in low and medium power applications. The deterministic pulse width modulation (PWM) methods like sinusoidal PWM (SPWM) could not be considered as an ideal choice for modern drives since they result mechanical vibration and acoustic noise, and limit the application scope. This is due to the incapability of the deterministic PWM strategies in sprawling the harmonic power. The random PWM (RPWM) approaches could solve this issue by creating continuous harmonic profile instead of discrete clusters of dominant harmonics. Insufficient filtering at dc link results in the amplitude distortion of the input dc voltage to the VSI and has the most significant impact on the spectral errors (difference between theoretical and practical spectra). It is obvious that the sprawling effect of RPWM undoubtedly influenced by input fluctuation and the discrete harmonic clusters may reappear. The influence of dc link fluctuation on harmonics and their spreading effect in the VSI remains invalidated. A case study is done with four different filter capacitor values in this paper and results are compared with the constant dc input operation. This paper also proposes an ingenious RPWM, a ripple dosed sinusoidal reference-random carrier PWM (RDSRRCPWM), which has the innate capacity of suppressing the effect of input fluctuation in the output than the other modern PWM methods. MATLAB based simulation study reveals the fundamental component, total harmonic distortion (THD) and harmonic spread factor (HSF) for various modulation indices. The non-ideal dc link is managed well with the developed RDSRRCPWM applied to the VSI and tested in a proto type VSI using the field programmable gate array (FPGA).

The Influence of Motor Ability of Elderly on IADL (노인의 운동능력이 IADL에 미치는 영향)

  • Um, Ki-Mai;Yang, Yoon-Kwon
    • Journal of Korean Physical Therapy Science
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    • v.8 no.1
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    • pp.821-831
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    • 2001
  • Motor ability were hypothesized to be major factors that may have an influence on IADL(instrumental activities of daily living). The purpose of this study was to investi gate the effect of motor ability of elderly on IADL. This study consisted of forty eight elder male and ninety elder female. The subjects were selected from L, S, Y-institution in kyoung ki do. The average age of elder male and female was 73.81, 71.38 years. The data were analyzed with t-test, repeated measurement, correlation test, regression test, using SPSS PC+ and MINITAB program. The measurement item of motor ability was muscle strength(left, right- grip strength), flexibility(sitting trunk flexion, trunk extension, leg raising while in a standing position), agility(whole body reaction test, standing up), power(sargent jump), balance (stork stand). IADL was measured with Philadelphia Geriatric Center IADL. The result of this study were the following : 1. The factor of significant difference of between elder male and female was muscle strength, flexibility, power but no significant difference was agility, balance. 2. Between IADL of elder male and female was no significant difference. 3. Correlation of IADL and Motor ability of elder male had effect on muscle strength and power, agility. Correlation of Body composition and Motor ability of elder female had effect on muscle strength and power, agility. As a result of this study, optimal motor ability of elder male and female had improved IADL. In addition to, this result of this study, it can suggested the consideration of the Health promotion program for elderly.

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Analysis of Positive Logic and Negate Logic in 1bit adder and 4 bit adder 74LS283 (1bit 전 가산기와 4bit 덧셈 연산기 74LS283에서 의정 논리와 부 논리에 대한 분석)

  • Chung, Tong-Ho;Chung, Tea-Sang;You, Jun-Bok
    • Proceedings of the KIEE Conference
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    • 2000.11d
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    • pp.781-783
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    • 2000
  • 1bit full adder have 3 input (including carry_in) and 2 outputs(Sum and Carry_out). Because of 1 bit full adder's propagation delay. We usually use 4-bit binary full adder with fast carry, 74LS283. The 74LS283 is positive logic circuit chip. But the logic function of binary adder is symmetrical, so it can be possible to use it not only positive logic but also the negative logic. This thesis use symmetrical property. such as $C_{i+1}(\bar{a_i}\bar{b_i}\bar{c_i})=C_{i+1}{\bar}(a_i,\;b_i,\;c_i)$ and $S_i(\bar{a_i}\bar{b_i}\bar{c_i})=\bar{S_i}(a_i,\;b_i,\;c_i)$. And prove this property with logic operation. Using these property, the 74LS283 adder is possile as the negation logic circuit. It's very useful to use the chip in negative logic. because many system chip is negative logic circuit. for example when we have negative logic chip with 74LS283. we don't need any not gate for 74LS283 input, and just use output of adder(74LS283) as the negation of original output.

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