• Journal of KSNVE
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• v.8 no.5
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• pp.964-973
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• 1998

In this paper we propose a levitation and imbalance compensation controller design methodology of magnetic bearing system. In order to achieve levitation and elimination of unbalance vibartion in some operation speed we use the discrete-time Q-parameterization control. When rotor speed p = 0 there are no rotor unbalance, with frequency equals to the rotational speed. So in order to make levitatiom we choose the Q-parameterization controller free parameter Q such that the controller has poles on the unit circle at z = 1. However, when rotor speed p $\neq$ 0 there exist sinusoidal disturbance forces, with frequency equals to the rotational speed. So in order to achieve asymptotic rejection of these disturbance forces, the Q-parameterization controller free parameter Q is chosen such that the controller has poles on the unit circle at z = $exp^{ipTs}$ for a certain speed of rotation p ( $T_s$ is the sampling period). First, we introduce the experimental setup employed in this research. Second, we give a mathematical model for the magnetic bearing in difference equation form. Third, we explain the proposed discrete-time Q-parameterization controller design methodology. The controller free parameter Q is assumed to be a proper stable transfer function. Fourth, we show that the controller free parameter which satisfies the design objectives can be obtained by simply solving a set of linear equations rather than solving a complicated optimization problem. Finally, several simulation and experimental results are obtained to evaluate the proposed controller. The results obtained show the effectiveness of the proposed controller in eliminating the unbalance vibrations at the design speed of rotation.

• Archives of Pharmacal Research
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• v.29 no.3
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• pp.224-234
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• 2006

We employed human SK-MEL-28 cells as a model system to identify cellular proteins that accompany N-(4-methyl)phenyl-O-(4-methoxy)phenyl-thionocarbamate (MMTC)-induced apoptosis based on a proteomic approach. Cell viability tests revealed that SK-MEL-28 skin cancer cells underwent more cell death than normal HaCaT cells in a dose-dependent manner after treatment with MMTC. Two-dimensional electrophoresis in conjunction with matrixassisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry analysis or computer matching with a protein database further revealed that the MMTC-induced apoptosis is accompanied by increased levels of caspase-1, checkpoint suppressor-1, caspase-4, NF-kB inhibitor, AP-2, c-Jun-N-terminal kinase, melanoma inhibitor, granzyme K, G1/S specific cyclin D3, cystein rich protein, Ras-related protein Rab-37 or Ras-related protein Rab-13, and reduced levels of EMS (oncogene), ATP synthase, tyrosine-phosphatase, Cdc25c, 14-3-3 protein or specific structure of nuclear receptor. The migration suppressing effect of MMTC on SK-MEL-28 cell was tested. MMTC suppressed the metastasis of SK-MEL-8 cells. It was also identified that MMTC had little angiogenic effect because it did not suppress the proliferation of HUVEC cell line. These results suggest that MMTC is a novel chemotherapeutic and metastatic agents against the SK-MEL-28 human melanoma cell line.

• Journal of Engineering Education Research
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• v.20 no.5
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• pp.59-73
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• 2017

This study aims to examine whether a gender works to make the difference on the university experiences of natural sciences and engineering major students; and the income and quality gap between the graduates. In this study, university experiences means job market and job searching related experiences such as job fair attending, The main research questions are as follows; fist, what are the significant university experiences related job preparation and application, and is there a gender gap on those experiences? Second, how is the job market performance of the national sciences and engineering graduates for their income level and quality job, and is there a gender gap on the job market performance of the sample? Third, which variables among the university experiences for job searching and application impacts the job quality and income level of the natural sciences and engineering graduates? To find out the research results, this study conducts a panel data analysis with GOMS (Graduates Occupational Mobility Survey) throughout survey year of 2006 to 2015, towards 568,264 as weighted value number. As analysis methods, this study carries out a descriptive analysis, ANOVA, discriminant analysis, linear regression and T-test. Therefore, here are the brief outputs of the study; first, for natural sciences and engineering students, the off-campus experiences such as job fair, job recruit festival and internship programs are more favored; second, female students are more likely to attend personal and self-driven job preparation programs; third, on job market performance, the graduates' income level and company scale rate are higher in the male but job stability is higher in the female; fourth, as a result of the linear regression, gender factor decides the income level in considerable degree; additionally, gender factor shows the difference of the job satisfaction and self-effectiveness on one's job as a qualitative variables. For obtaining strictness, university program factors are controlled through model fitness process. As above, this study finds out the main factors of university life of natural sciences and engineering graduates which are related their job searching and preparation experiences and figures out stronger factors in job market; and examines the statistically significance of the gender in this casual-effect relationship between job preparation and job quality of the graduates.

• Journal of Korean Society of Steel Construction
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• v.18 no.6
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• pp.697-706
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• 2006

Tower crane's wall tie is generally used for extending of mast height according to rising of lifting height. In order to get wall tie member force this problem, this study concerning wall tie is based on load data described in manual book of 290HC model. This study made the equation of wall tie member force and computer programming for calculating wall tie member force and then get ${\theta}-P$ curves(angle-wall tie force). After considering the ${\theta}-P$ curves, optimum angle range ($48.4^{\circ}{\sim}77.2^{\circ}$) about wall ties (A), (C) members was obtained. Member force of wall tie (B) was changed from tension to compression or from compression to tension at $74^{\circ}$ in service and $54^{\circ}$ in out of service. When both horizontal force($H_A$) and torsional moment ($M_D$) were varied from (+) to (-), wall tie force(A, B, C) were changed almost symmetrically about ${\theta}$-axis. Because this study was based on wall tie analysis conditions, wall tie members in symmetric and ideal geometry shape used for analizing wall tie of tower crane, it is necessary to have more careful verification in order to apply generally the results of this study.

• Korean Journal of Social Welfare
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• v.37
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• pp.381-405
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• 1999

The primary purpose of this study is to design and perform juvenile group program and. to evaluate the effectiveness of that program The group was consisted of 10 fourth-grade elementary school boys who have had such factors that might force themselves to be delinquent, for example, broken family, having delinquent siblings or friends, family violence, and etc. The group had been held once a week and continued for 5 months. The effectiveness of that program is evaluated quantitatively and qualitatively through goal-attainment model. The ultimate goal of this program is reduction of delinquency stimulating factors which are operationalized with overall self-esteem - family related self-esteem, friend related self-esteem, and school related self-esteem. Quantitative evaluation is performed by pre- and post-test with Hare Self-Esteem Scale. Case records, family records, group activities records, and reports from schools are analyzed for the qualitative evaluation. According to paired samples t-test scores, average overall self-esteem scores of experimental group members were escalated from 67.57 to 74.86, and this difference between pre-test and post-test was statistically significant. Difference of experimental group was bigger and more striking than that of control group. These results suggest that designed and performed group program in this study would be effective in preventing juvenile from being delinquent.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.10
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• pp.1565-1574
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• 2018

Objective: The aim of the present study was to identify genetic variants based on RNA-seq data, obtained via transcriptome sequencing of muscle tissue of pigs differing in muscle histological structure, and to verify the variants' effect on histological microstructure and production traits in a larger pig population. Methods: RNA-seq data was used to identify the panel of single nucleotide polymorphisms (SNPs) significantly related with percentage and diameter of each fiber type (I, IIA, IIB). Detected polymorphisms were mapped to quantitative trait loci (QTLs) regions. Next, the association study was performed on 944 animals representing five breeds (Landrace, Large White, Pietrain, Duroc, and native Puławska breed) in order to evaluate the relationship of selected SNPs and histological characteristics, meat quality and carcasses traits. Results: Mapping of detected genetic variants to QTL regions showed that chromosome 14 was the most overrepresented with the identification of four QTLs related to percentage of fiber types I and IIA. The association study performed on a 293 longissimus muscle samples confirmed a significant positive effect of transforming acidic coiled-coil-containing protein 2 (TACC2) polymorphisms on fiber diameter, while SNP within forkhead box O1 (FOXO1) locus was associated with decrease of diameter of fiber types IIA and IIB. Moreover, subsequent general linear model analysis showed significant relationship of FOXO1, delta 4-desaturase, sphingolipid 1 (DEGS1), and troponin T2 (TNNT2) genes with loin 'eye' area, FOXO1 with loin weight, as well as FOXO1 and TACC2 with lean meat percentage. Furthermore, the intramuscular fat content was positively associated (p<0.01) with occurrence of polymorphisms within DEGS1, TNNT2 genes and negatively with occurrence of TACC2 polymorphism. Conclusion: This study's results indicate that the SNP calling analysis based on RNA-seq data can be used to search candidate genes and establish the genetic basis of phenotypic traits. The presented results can be used for future studies evaluating the use of selected SNPs as genetic markers related to muscle histological profile and production traits in pig breeding.

• The Korea Journal of Herbology
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• v.35 no.6
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• pp.11-19
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• 2020

Objective : The genus Glycyrrhiza has been used in food and traditional herbal medicine. Glycyrrhiza new varieties Wongam and Sinwongam have been developed by Korea Rural Development Administration and investigated to register on Korean Pharmacopoeia of the Ministry of Food and Drug Safety. The aim of this study is to investigate the immunomodulatory effect of Wongam and Sinwongam comparing with listed Glycyrrhiza species (Glycyrrhiza uralensis Fischer and G. glabra Linne) for evaluations about pharmacological effect of Glycyrrhiza new varieties. Methods : We studied the immunomodulatory effect of Wongam and Sinwongam compared with G. uralensis and G. glabra using THP-1 cell in vitro model. The cells were treated with phorbol 12-myristate 13-acetate (PMA) for differentiation and stimulated with lipopolysaccharides (LPS) to induce immune activation. We analyzed and compared the effects Glycyrrhiza new varieties and listed Glycyrrhiza species using nitric oxide (NO) assay, western blot, and reverse transcription-quantitative polymerase chain reaction analysis. 1) Results : Wongam and Sinwongam showed no cytotoxicity in THP-1 cells. Wongam and Sinwongam, and listed Glycyrrhiza species increased NO production, and cyclooxygenase (COX)-2 expression with or without LPS in differentiated THP-1 macrophages. Furthermore, Wongam and Sinwongam and listed Glycyrrhiza species upregulated the mRNA expressions of T helper type 1 (Th 1)-associated cytokines in LPS-stimulated THP-1 macrophages. Conclusion : These results indicated that Wongam and Sinwongam would have effect of enhancing immune response through the increase of NO and COX-2 expression, and activate Th1-associated cytokines. The findings of this study suggest the wide applicability of Glycyrrhiza new varieties.

• The KIPS Transactions:PartC
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• v.9C no.4
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• pp.513-522
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• 2002

Current end-to-end congestion control depends only on the information of end points (using three duplicate ACK packets) and generally responds slowly to the network congestion. This mechanism can't avoid TCP global synchronization which TCP congestion window size is fluctuated during congestion occurred and if RTT (Round Trip Time) is increased, three duplicate ACK packets is not a correct congestion signal because congestion maybe already disappeared and the host may send more packets until receive the three duplicate ACK packets. Recently there is increasing interest in solving end-to-end congestion control using active network frameworks to improve the performance of TCP protocols. ACC (Active congestion control) is a variation of TCP-based congestion control with queue management In addition traffic modifications nay begin at the congested router (active router) so that ACC will respond more quickly to congestion than TCP variants. The advantage of this method is that the host uses the information provided by the active routers as well as the end points in order to relieve congestion and improve throughput. In this paper, we model enhanced ACC, provide its algorithm which control the congestion by using information in core networks and communications between active routers, and finally demonstrate enhanced performance by simulation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.8
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• pp.292-300
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• 2016

This paper reports a descriptive correlation to explore the relationship among nursing professionalism, ego-resilience, and empowerment in nursing students. A convenience sample of 195 subjects were recruited from four colleges. Subsequently, a survey was conducted from March 1st to 31th 2016. The data were collected by questionnaires and analyzed using SPSS 22.0 program, using descriptive statistics, Pearson's correlation coefficient, and multiple regression. The mean value of the study was as follows: nursing professionalism, $3.84{\pm}.47$; ego-resilience, $3.51{\pm}.58$; and empowerment, $2.79{\pm}.51$. There were significant positive correlations among ego-resilience (r=.455, p<.001), empowerment (r=.325, p<.001), and nursing professionalism. Significant positive correlations between ego-resilience and empowerment were found (r=.696, p<.001). Hence, ego-resilience and empowerment were determined to be factors that influence nursing professionalism. Ego-resilience was more influential for nursing professionalism than empowerment. The regression model explained 23.0% of nursing professionalism. In conclusion, to increase nursing professionalism in nursing students, it is necessary to develop educational programs and strategies that focus on improving ego-resilience and empowerment.

• Journal of Pharmacopuncture
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• v.6 no.1
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• pp.76-94
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• 2003

Objectives : The purpose of this study was to investigate Acute$\cdot$Subacute Toxicity and Anti-cancer Effect of K-Herbal-acupuncture in mice and rats. Methods : Balb/c mice were injected intraperitoneally with K-herbal-acupuncture for $LD_{50}$ and acute toxicity test. Sprague-Dawley rats were injected intraperitoneally with K-herbal-acupuncture for subacute toxicity test. K-Herbal-acupuncture was injected on abdomen of mice with S-180 cancer cell line. Result : 1. $LD_{50}$ of K-Herbal-acupuncture was limited $4{\times}10^{-3}$ml/kg~$2{\times}10^{-3}$ml/kg by the test. 2. In acute toxicity test, all of mice were down to the moving reflex, but the weight of mice was increased in treatment group, compared with the normal group. (P<0.05) 3. In acute toxicity test of serum biochemical values of mice, glucose was increased in treatment II group, total cholesterol was increased both treatments.(P<0.05) 4. In subacute toxicity test, the clinical signs of toxication was down to the moving reflex, but it is not severe like acute toxicity test, and observed weight loss at the treatments. 5. In subacute toxicity test, liver weight was decreased compared with the normal group. (P<0.05) 6. In subacute toxicity test of complete blood count test (CBC) of rat, HCT was decreased in treatments, compared with the normal group.(P<0.05) 7. In subacute toxicity test of serum biochemical values of rat, uric acid and triglyceride were decreased, and glucose was increased in treatment groups compared with the control group. (P<0.05) 8. Median survival time was increased about $45\%$ in treatment groups compared with the control group.(P<0.05) 9. Natural killer cell activity was increased in B16F10 lung cancer model, but it was not in sarcoma-180 abdomen cancer. 10. In interleukin-2 productivity test, treatment groups didn't show significant change in lung cancer and abdomen cancer, compared with the normal group.(P<0.005) 11. In making an examination of metastatic cancer with the naked eye, melanoma metastasized in the Lung of C57BL/6 mice. The treated group showed more Melanoma than the control in the numbers and volume. Conclusion : According to the result, K-herbal-acupuncture need further study to know the function and effect in cancer.