• Title/Summary/Keyword: T 방법

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The inhibitory effect of physiological pattern of testosterone on luteinizing hormone secretion in sheep (면양에서 생리적 분비형태의 테스토스테론이 황체형성호르몬의 분비 억제에 미치는 효과)

  • Rhim, Tae-jin;Park, Kyoung-sik
    • Korean Journal of Veterinary Research
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    • v.35 no.2
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    • pp.271-278
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    • 1995
  • The objective of the present study was to investigate the inhibitory effect of physiologically pulsatile pattern of testosterone(T) on luteinizing hormone(LH) in wethers. To do this, 3 separate experiments were conducted. Infusion rates and patterns needed to produce normal T secretory profiles found in intact rams were established in Experiment 1, the time-course of the suppressive effect of T on circulating LH concentrations was determined in Experiment 2, and the effectiveness of a pulsatile versus a constant pattern of T to suppress LH secretion in wethers was compared in Experiment 3. In Experiment 1, three different doses(25, 50 or $100{\mu}g$) of T were injected intravenously to animals to do pharmacokinetic analysis of T. Elimination rate constant, volume of distribution, and total body clearance of T averaged $0.18min^{-1}$, 0.531/kg BW, and 0.091/min/ kg BW, respectively. In Experiment 2, three different doses(192,384, or $768{\mu}g/kg/24h$) of T were infused at 4h intervals for 3 days into animals to evaluate the time course of the inhibitory effect of T on mean LH concentration. As duration of T infusion increased, mean LH concentrations gradually reduced. Mean LH concentrations were significantly lower at day 2 or day 3 than at day 0. However, mean LH concentrations did not differ between day 0 and day 1 or between day 2 and day 3. In Experiment 3, animals were subjected to two different intravenous infusion regimens for 3 days: constant T($768{\mu}g/kg/24h$) and pulsatile(one pulse every 4h) T($768{\mu}g/kg24h$). Blood samples were collected at 10-min intervals for 4h both prior to infusion and during the last 4h of the infusion. Mean LH was more suppressed(p=0.045) by constant T than by pulsatile T. LH pulse amplitude was not affected by constant T or pulsatile T. LH interpulse interval was increased more(p=0.034) by constant T than pulsatile T.

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A Study on the P~q~t Charts Applicability for Quality Improvement of Water-Sealing&Reinforcement Grouting in Tunneling Work Underneath the City (도심지 지하 터널시공 중 차수·보강 그라우팅 공사의 품질향상을 위한 P~q~t charts 적용성 연구)

  • Kim, Jin-Chun;Kim, Seok-Hyun;Yoo, Byung-Sun;Kang, Hee-Jin
    • Journal of Korean Society of Disaster and Security
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    • v.14 no.3
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    • pp.51-63
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    • 2021
  • This study is for the quality improvement of water-sealing & reinforcement grouting in tunnel of the construction of the underground transportation network underneath the city. Existing tunnel grouting process did not technically utilize P~q~t charts fully. It is due to the absence of technical methods to decide how P~q~t charts change in the presence of trouble and what the change represents in grouting. There were no standards to decide which chart pattern represents which ground characteristics, how to categorize ground types, and how to take measures according to the standards. This paper studies on the grouting type, ground characteristics, ground type categorizing method, and countermeasures for both general and algorithm-processed grouting in soil and rock layer to address the aforementioned problems. Newly improved P~q~t charts from grouting in soil was categorized into six different types. Different characteristics and categorization method was developed for each type. Countermeasures for each type of grouting process were developed so that on-site application can be readily available. Improved P~q~t charts for rock layer also have six different types of grouting. Each type was given the countermeasures for rock layer grouting process for easier applications. Therefore, it is expected to be used through out the entire process of grouting from preparation to the last report of the water-sealing & reinforcement grouting in tunnel of the construction of the underground transportation network underneath the city.

Luminescence Immunoassays and Their Applications for Dihydrotestosterone and Testosterone( I );Establishment of LIA. (Dihydrotestosterone과 Testosterone의 섬광면역 측정법과 응용( I );측정법의 정립)

  • Yoon, Yong-Dal;Kim, Sung-Rye
    • Clinical and Experimental Reproductive Medicine
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    • v.14 no.2
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    • pp.138-148
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    • 1987
  • 5${\alpha}$-dihydrotestosterone(DHT)과 testosterone(T)은 남성 생식기관의 주 생성 호르몬들로 그 구조가 매우 비슷하여 이들 각 개를 특이하게 측정(specific determination)하는 방법이 개발되지 않고 있다. 본 연구는 고속액체 크로마토그라피(HPLC)를 이용하여 이들을 분리한 후 섬광면역측 정법(Luminescence immunoassay, LIA)으로 정량하는 방법을 개발하여 이들의 응용 가능성을 검토하고져 하였다. DHT와 T의 retention time은 각각 10.3min, 17.6min이었다. DHT-LIA와 T-LIA에 서 다른 스테로이드들과의 교차반응도는 방사면역측정법(RIA)과 대동소이하였다. 정도관리(quality control) 시료의 intra-assay variation은 DHT-LIA가 8.7%, T-LIA가 6.0%의 변이계수를 나타내었고, inter-assay variation의 변이계수는 각각 12.0% 및 15.3%이었다. 실측치(y)와 기대치(x)간의 관계를 보면, DHT-LIA경우는 Y=0.94X+0.9(r=0.989), T-LIA는 Y=1.01X+0.06(r =0.988)로 두 측정치 사이에는 통계적으로 유의한 차이가 없었다. 위의-측정방법을 이용하여 DHT-enanthate와 T-enanthate 처리후 혈청내 DHT 및 T의 농도변화를 조사한 실험결과 LIA와 RIA의 값사이에 유의한 차이가 없었다. 위의 결과로 보아 본 실험에서 개발된 DHT와 T의 섬광면역측정법은 정립되었다고 사려된다.

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Studies on the Oranization and Expression of tRNA Genes in Aspergillus nidulans (V) The Molecular Structure of $tRNA^{Arg}$ in Aspergillus nidulans (Aspergillus nidulans의 tRNA유전자의 구조와 발현에 관한 연구 V Aspergillus nidulansd의 $tRNA^{Arg}$ 분자구조)

  • 이병재;강현삼
    • Korean Journal of Microbiology
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    • v.24 no.2
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    • pp.79-85
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    • 1986
  • We have determined the sequence of $tRNA^{Arg}$ of A. nidulans partially by enzymatic rapid RNA sequencing technique. The sequence was 5'GGCCGGCUGGCCCAAXUGGCAAGGXUCUGAXUACGAAXCAGGAGAUUGCACXXXXXGAGCXXUXXGUCGGUCACCA3' The cloverleaf structure was made from above data. As a result, the anticodon sequence was identified as ACG. This result was confirmed with charging test. The complete sequence was proposed by supplementing the DNA sequence to and by assigning the position of minor bases to this RNA sequence.

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A Study on the T-DMB Standard for Pay Video Service (유료 비디오 서비스 제공을 위한 지상파 DMB 표준 연구)

  • Bae, Byungjun;Oh, Sungheun;Yun, Joungil;Yang, Kyu-Tae;Lim, Hyoungsoo
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2013.06a
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    • pp.111-112
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    • 2013
  • 기존의 T-DMB 표준 문서에서는 T-DMB 기반의 비디오 서비스를 무료 서비스로 규정하여 스크램블링을 수행할 수 없도록 제한 사항을 두고 있다. 그러나, 최근의 T-DMB 수익 구조 개선의 노력과 차세대 T-DMB(AT-DMB) 기술의 등장으로 T-DMB 기반의 유료 비디오 서비스에 대한 관심이 점차 증대되고 있다. 본 논문에서는 유료 서비스 관련 기존 T-DMB 표준 문서들을 분석하여, T-DMB 채널을 통한 유료 비디오 서비스를 제공하기 위한 효율적인 시그날링 및 스크램블 방법을 제안한다. 제안된 방법은 기존의 비디오 서비스와 역호환성을 유지하여 이미 보급된 T-DMB 수신 단말에 문제점을 야기하지 않는 것을 특징으로 한다.

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Implementation of a DB-based Virtual Filesystem for IoT Service Platform using Linux FUSE (DB 및 리눅스 FUSE 기반 IoT 서비스 플랫폼을 위한 가상 파일시스템 구현)

  • Lee, Hyung-Bong
    • Proceedings of the Korea Information Processing Society Conference
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    • 2015.04a
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    • pp.103-104
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    • 2015
  • IoT의 주요 구성요소는 기존의 데스크 탑 외에 디바이스 즉, 단말 기기들이 주류를 이룬다. 이러한 IoT 디바이스들은 데이터의 유형이나 접근 방법이 다양하고, 실시간적 데이터 생산과 제어를 위한 양방향 데이터 접근 지원을 필요로 한다. 이러한 IoT 디바이스를 연결하여 클라우드 형 서비스로 개발하기 위해서는 디바이스 속성 관리가 용이한 도메인 관리 방법과 디바이스에 대한 일관된 접근 인터페이스를 제공하는 플랫폼이 필요하다. 이 논문에서는 리눅스 파일시스템 후면 즉, 사용자 영역에 리눅스 파일 시스템 스타일의 DB 기반 가상 파일시스템을 구축하여 IoT 디바이스를 연결하고 관리하는 프레임워크를 제시한다. 구현 가상 파일시스템은 계층적 디렉터리 체계를 DB에 유지하면서 단말 노드에는 지리적으로 산재한 IoT 디바이스들에 대한 속성 정보를 관리한다. 디렉터리 및 IoT 디바이스의 추가 삭제 검색 등 도메인 관리는 mkdir. mknod, ls, find 등 리눅스 고유 명령어로 이루어지고, 모든 IoT 디바이스에 대한 접근은 open(), read(), write(), close() 등 POSIX 인터페이스를 통해 가능하다.

Optimum Extraction Methods of Volatile Compounds in Beef Extract Powder (쇠고기 엑기스 분말 휘발성 성분의 최적 추출방법에 관한 연구)

  • Kim Hun;Cho Woo-Jin;Jeong Eun-Jeong;Ahn Jun-Suck;Lim Chi-Won;Yoo Young-Jae;Kim Kwang-Ho;Cha Yong-Jun
    • The Korean Journal of Food And Nutrition
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    • v.17 no.4
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    • pp.412-419
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    • 2004
  • In odor to select optimum extraction methods of volatile compounds in beef extract powder(BEP) as basic data for the development of a new detection method of irradiated BEP, four extraction methods, such as solid phase microextraction with polar fiber(S-PD) and non-polar fiber(S-CD), purge and trap(P&T) and liquid liquid continuous extraction(LLCE) methods, were tested with gas chromatography/mass spectrometry method. A total of 106 volatile compounds including 22 hydrocarbons, 7 aldehydes, 6 ketones, 13 alcohols, 6 sulfur-containing compounds, 19 nitrogen-containing compounds, 6 aromatic compounds, 17 terpenes, 8 furans and 2 miscellaneous compounds were detected in BEP by four detection methods. The most compounds(62 compounds) were detected by S-PD method, followed by P&T(43), LLCE(38) and S-CD method(30). Among these methods, S-PD and P&T methods showed a complementary interrelationship to detect volatile compounds as S-PD method showed high detectabiltiy to all compound groups except hydrocarbons and ketones, which had high volatility and low molecular weight(less than RI 1200), but P&T method showed the contrary pattern to that of S-PD method. Moreover, the most of volatile compounds detected by S-CD and LLCE methods were also detectable by S-PD or/and P&T methods. Therefore, the simultaneous application of S-PD and P&T methods were selected as the optimum volatile extraction methods of BEP.

Effects of Body Weight Control Methods during Rearing Phase on Laying Performance in Broiler Breeder Pullets (육용종계 육성기 체중조절 방법이 산란기 생산성에 미치는 영향)

  • Na, Jae-Cheon;Lee, Sang-Jin;Jang, Byeong-Gwi;Kim, Sang-Ho;Kim, Hak-Kyu;Suh, Ok-Seok;Lee, Gin-Keon;Yu, Dong-Jo;Ha, Jeong-Gi
    • Korean Journal of Poultry Science
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    • v.30 no.4
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    • pp.229-233
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    • 2003
  • A study was conducted to investigate the effects of different BW control methods during rearing on laying performance of broiler breeder pullets. D-old 540 female breeder chicks (Arbor Acres) were assigned to three treatments consisted of standard BW (Control), 110% of standard BW at 12 wk of age (T1), and 90% of standard BW at 12 wk of age (T2), with three replicates of 60 birds per replicate (pen) for each treatment. At 20 wk of age, all birds from three treatments reached the BW reqired in the Arbor Acres Manual. There were no significant differences in egg production, egg weight and viability during laying period(p>0.05). However, total egg production rates were improved in T2 and T3. Average egg weight was the highest in T1 among all treatments. Fertility and hatchability were similar among treatments, but T2 tended to be higher than other treatments at 37 and 53 wk of age. No significant difference was found in hatchability among three treatments. The number of hatching egg of T2 reached 168 per year, showing higher number of eggs than did the other treatments. The number of hatched chicks in T2 was 131, which was also higher than the other treatments, but the difference was not significant. It appears that the laying performance of broiler breeder hens could be improved when their BW at 12 wk of age are kept at 90% of standard BW, and reach the standard BW at 20 week of age.

Systematic Development of Mobile IoT Device Power Management: Feature-based Variability Modeling and Asset Development (모바일 IoT 디바이스 파워 관리의 체계적인 개발 방법: 휘처 기반 가변성 모델링 및 자산 개발)

  • Lee, Hyesun;Lee, Kang Bok;Bang, Hyo-Chan
    • Journal of KIISE
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    • v.43 no.4
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    • pp.460-469
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    • 2016
  • Internet of Things (IoT) is an environment where various devices are connected to each other via a wired/wireless network and where the devices gather, process, exchange, and share information. Some of the most important types of IoT devices are mobile IoT devices such as smartphones. These devices provide various high-performance services to users but cannot be supplied with power all the time; therefore, power management appropriate to a given IoT environment is necessary. Power management of mobile IoT devices involves complex relationships between various entities such as application processors (APs), HW modules inside/outside AP, Operating System (OS), platforms, and applications; a method is therefore needed to systematically analyze and manage these relationships. In addition, variabilities related to power management such as various policies, operational environments, and algorithms need to be analyzed and applied to power management development. In this paper, engineering principles and a method based on them are presented in order to address these challenges and support systematic development of IoT device power management. Power management of connected helmet systems was used to validate the feasibility of the proposed method.

도서관학에서의 비교 연구 방법론

  • 남태우
    • Journal of the Korean Society for information Management
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    • v.5 no.2
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    • pp.3-22
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    • 1988
  • The purpose of this paper is to help understand of the, definitio~~ of, componativelibraianship and the methodology of comparative study in librariansliip. Comparative librarial~sl~ip may be defined as the systematic anallsis of library derelopmetit, practices, or problems as they occur under different circumstances (most usually in different count r ~ e s ) , considered in the c o ~ t t x t of tlle relevant historical, geographic, political, economic, social, cultural, and other determinant backgrourd factors found in the situations under study. Essentially it co~~stitutes an important approach to the search for cause and effect in library development, and tu tl~e understandillg of library problems. The mctl~odology of comparatiw study i n libranianship includes four steps; i)description, iilinterpret at ion, iii\ulcorner juxtaposition, iv! comparison.

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