• Title/Summary/Keyword: Systematic Review Analysis

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A Study on The Improvement of Related Regulation System for The Utility Tunnel Activation (지하공동구 활성화를 위한 관련규정 체계 개선에 관한 연구)

  • Oh, Won-Joon;Cho, Choong-Yeun;Lee, Min-Jae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.8
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    • pp.563-571
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    • 2020
  • The purpose of a utility tunnel is to prevent repeated excavation as well as disasters and calamity. Domestic utility tunnels have been built in new town development plans. Currently, it is difficult to establish a utility tunnel due to a conflict of opinions by organization and financing. In this paper, research was conducted based on systematic procedures to suggest ways of improving the activation of utility tunnels in new cities and existing cities. First, a survey was conducted on the laws and status of utility tunnels, and problems were derived based on the review and analysis of the status. Finally, a method suggesting improvement measures to solve problems was applied. Based on the related laws and problems, the status of the development project was analyzed to select the installation scale in the utility tunnel, and the appropriate scale was reviewed through economic feasibility analysis of the installation scale under 2 million square meters. Considering the new city and the existing city, it was proposed to support administrative expenses to reduce the burden on additional installation areas and occupied institutions in a utility tunnel. In addition, improvement plans were presented for the details of the master plan for reviewing the installation regional of the utility tunnel. This paper will help officials to work smoothly when planning and installing utility tunnels in the future.

Significant Efficacy of Additional Concurrent Chemotherapy with Radiotherapy for Postoperative Cervical Cancer with Risk Factors: a Systematic Review and Meta-analysis

  • Qin, Ai-Qiu;Liang, Zhong-Guo;Ye, Jia-Xiang;Li, Jing;Wang, Jian-Li;Chen, Chang-Xian;Song, Hong-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.8
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    • pp.3945-3951
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    • 2016
  • Background: Whether concurrent chemotherapy treatment is superior to radiotherapy alone as an adjuvant regimen for postoperative cervical carcinoma with risk factors remains controversial. Materials and Methods: A literature search strategy examined Pubmed, Embase, the Cochrane Library, the China National Knowledge Internet Web, the Chinese Biomedical Database and the Wanfang Database. Article reference lists and scientific meeting abstracts were also screened. Controlled trials comparing concurrent chemoradiotherapy versus radiotherapy alone in postoperative cervical cancer were included. The methodological quality of non-randomized controlled trials was evaluated using the Newcastle-Ottawa Scale. Randomized controlled studies were evaluated with the Cochrane handbook. A meta-analysis was performed with RevMan 5.3. Results: A total of 1,073 patients from 11 clinical trials were analysed, with 582 patients in the concurrent chemoradiotherapy group and 491 patients in the radiotherapy group. Hazard ratios (HR) of 0.47 (95% CI 0.31-0.72) and 0.50 (95% CI 0.35-0.72) were observed for overall survival and progression-free survival, indicating a benefit from the additional use of concurrent chemotherapy. Subgroup analyses demonstrated that cervical cancer with high risk factors significantly benefitted from concurrent chemotherapy when examining overall survival (HR 0.44, 95% CI 0.28-0.67) and progression-free survival (HR 0.48, 95% CI 0.33-0.70), but patients with intermediate risk factors showed no benefit from concurrent chemotherapy in overall survival (HR 1.72, 95% CI 0.28-10.41) and progression-free survival (HR 1.09, 95% CI 0.19-6.14). No significant differences were observed for grade 3-4 anaemia (risk ratio (RR) 3.87, 95% CI 0.69-21.84), grade 3-4 thrombocytopenia (RR 3.04, 95% CI 0.88-10.58), grade 3-4 vomiting or nausea (RR 1.71, 95% CI 0.27-10.96), or grade 3-4 diarrhoea (RR 1.40, 95% CI 0.69-2.83). Significant differences were observed for grade 3-4 neutropenia in favour of the radiotherapy group (RR 7.23, 95% CI 3.94-13.26). Conclusions: In conclusion, concurrent chemoradiotherapy improves survival in postoperative cervical cancer with high risk factors but not in those with intermediate risk factors.

Meta-analysis of the Efficacy of Infliximab in Patients with Moderate-Severe Ulcerative Colitis (중등도-중증 궤양성 대장염 환자에서 infliximab의 치료효과에 대한 메타분석)

  • Kim, Jong Yoon;Lee, Sukhyang;Rhew, Ki Yon
    • Korean Journal of Clinical Pharmacy
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    • v.22 no.3
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    • pp.251-259
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    • 2012
  • Ulcerative colitis (UC) is characterized by a life-long chronic course with remissions and exacerbations. Use of biological therapies may reduce or delay the surgical procedures in patients with UC. The aim of this study was to determine the impact of infliximab (IFX) use on the rate of remission, surgical interventions, and the effect on quality of life in patients with moderate to severe UC. Literature was searched for studies that investigated the efficacy of IFX on the rate of remission, colectomy and quality of life (QoL) between January 1990 and June 2012 at MEDLINE, January 1988 and June 2012 at EMbase and others. Eleven trials were included in the meta-analysis; divided into placebo controlled 8 trials and intravenous corticosteroid controlled group 3 trials. In comparison to placebo control groups, patients who received IFX had an odds ratio (OR) of 3.712 (95% CI: 2.714, 5.079) for the short-term clinical remission, and 3.053 (95% CI: 2.044, 4.559) for the rate of long-term remission. In colectomy rate and quality of life (QoL), odds ratio were 0.566(95% CI: 0.387, 0.827) and 0.658 (0.505, 0.811) respectively. Any adverse reactions including infections, infusion reaction, rash and arthralgia were equivalent in both groups. Compared with intravenous corticosteroid controlled group, patients who received IFX had lower remission rate with short-term odds ratio 0.227 (95% CI: 0.033, 1.556) and long-term odds ratio 1.054 (95% CI: 0.317, 3.502) respectively. However, statistical significance was not showed with both two analyses. The higher adverse drug reaction (ADR) rates were occurred in the corticosteroid controlled groups. 73.3% of patients treated corticosteroid reported Cushing-like syndrome with moon face. In conclusion, IFX does increase remission rate and decrease the rate of colectomy in patients with UC without elevating any adverse reactions significantly. IFX also improves QoL in moderate to severe UC patients. It would not exceed the efficacy of intravenous corticosteroid, whereas intravenous corticosteroid also reported high rate of adverse reactions.

Development of a Classification Scheme for Management of Technology Research - Approach on Research Designs and Methodologies - (기술경영 연구 분야의 연구 분류체계 제시에 관한 연구 - 연구 설계와 연구 방법론을 중심으로 -)

  • Lee, Donggeol;Lee, Heesang;Yoon, Inhwan
    • Management & Information Systems Review
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    • v.35 no.4
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    • pp.269-287
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    • 2016
  • This paper proposes the newly developed a classification scheme for Management of Technology (MOT) research, by analyzing research papers published in major academic journals of MOT. To refine our proposed classification, we conducted a contents analysis after collecting 696 papers published in 11 major international journals and 2 representative domestic journals including Journal of Korean Technology Innovation Society, from 2006 to 2012. Our findings show that this classification scheme is composed of total 8 methodologies within each research design such as conceptual qualitative, empirical qualitative, conceptual quantitative, and conceptual quantitative researches. In addition, we provide research reviews based on characteristics between 1) domestic and foreign researchers, 2) domestic and international journals, and 3) different major domestic journals as follows. Firstly, the underlying trends of research design and methodologies in MOT research are concentrated in empirical studies regardless of the origin of researchers and journals. However, the proportion of theoretical discussion in the international journals is higher than that of theoretical discussion in the domestic journals. Secondly, there are many more empirical qualitative researches and archival researches written in the Journal of Korean Technology Innovation Society, whereas the proportion of empirical quantitative research and conceptual research published in the Journal of Technology Innovation is higher than that. From the results, this paper will contribute to choosing research designs and methodologies more suitable to research purpose for future MOT researchers and provide the direction for concrete systematic approach on research designs and methodologies.

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A Study on the Relative Importance of Evaluation Factors for Improvement of Port Security (항만보안 강화를 위한 평가요인과 상대적 중요도 분석)

  • Kang, Min-Gu;Kim, Hwa-Young
    • Journal of Navigation and Port Research
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    • v.43 no.1
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    • pp.49-56
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    • 2019
  • The purpose of this study was to extract the evaluation factors and assess the relative importance between the factors. For this purpose, the evaluation factors were extracted through literature review and the process of brainstorming with experts, who are related to port security. The evaluation factors were then classified into four higher factors and twelve sub- factors through the use of the AHP method. A survey on the classified factors was conducted by experts composed of public officials, port authority employees and education institutions officials. We also carried out statistical tests to determine the perception gap of weights between the groups. As a result of a relative importance analysis of strength, the security operating system factor was highest, followed by improvement of hardware facilities and increase of security personnel. There was a difference in perception among the groups in policy support, facility support and personnel resources budget support. The results of the analysis show that the strength operating system through the establishment of an integrated monitoring system is a priority. It is necessary to understand the difference of perception between groups and build a systematic cooperation system. The evaluation factors extracted from this study can be used for the measurement of port security efficiency in further work.

A Systematic Review and Meta-Analysis of the Effects of Simultaneous Dual-Task Training on Executive Function in Older Adults (동시적 이중과제 훈련이 노인의 실행기능에 미치는 효과: 체계적 고찰 및 메타분석)

  • Jeun, Yu-Jin;Park, Jin-Hyuck
    • Therapeutic Science for Rehabilitation
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    • v.10 no.3
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    • pp.23-41
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    • 2021
  • Objective : The purpose of this study was to analyze the effects of simultaneous dual-task training to assess executive function in older adults. Methods : We searched the PubMed, EMBASE, Cochrane, Web of Science, and RISS databases of publicated studies in the past decade. Seven studies were selected based on the inclusion and exclusion criteria. Qualitative assessment and meta-analysis were performed for the seven studies. Results : A randomized controlled trial design was used in the selected studies, and PEDro Scores above seven were obtained. The Trial Making Test (TMT) evaluated the effects of dual-task training on executive function in four studies. The Color Trail Test (CTT) was used in two studies, and Stroop test was used in three studies. The effect size for total executive function was 0.38, which was small. The effect sizes for TMT and CTT were 0.37. Stroop Test was 0.34, demonstrating that their effect sizes were also small. Only significant effects in total executive function, TMT, and CTT showed significant effects (all p<0.05). Conclusion : This study confirmed that dual-task training was effective in improving executive function in older adults. To improve the effectiveness of dual-task training, the difficulty of the dual-task training should be considered. It is also necessary to implement assessments that can evaluate performance under dual-task conditions as well as conventional test tools for executive function. In the future, dual-task training could be used as an appropriate intervention for executive function in older adults to delay the onset of dementia.

A Meta-analysis on Antecedents and Consequences of Technological Innovation: Focused on Empirical Analyses of South Korea's SMEs (기술혁신의 요인과 성과에 관한 메타분석: 우리나라 중소기업에 관한 실증분석 연구를 대상으로)

  • Kim, Juil;Kim, Minseo;Park, Hyesu
    • Korean small business review
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    • v.42 no.2
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    • pp.43-67
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    • 2020
  • Studies on technological innovation of SMEs have made remarkable growth both qualitatively and quantitatively, but each study has a limitation to generalize due to lack of data, diversity of methodologies and variables. Therefore, a systematic and comprehensive statistical approach to obtain generalized conclusions through numerous empirical studies can help both the strategic decision making of SMEs and the government's innovation policies. The purpose of this study is to comprehensively analyze the technological innovation process of SMEs through meta-analysis. For this, the antecedents of technological innovation, the relationship between technological innovation and management performance of SMEs were analyzed. The results of using 62,512 samples from 111 domestic empirical studies were as follows; First, to improve the technological innovation of SMEs, internal cooperation, innovation culture, dynamic capabilities, and absorptive capacity were important antecedents. Second, in terms of IP performance, which was introduced as a proxy for technological innovation, human resource management, technological opportunities, commercialization capabilities, financial resources, and R&D expenditure. Third, technological innovation has a medium-sized effect on financial performance, however the effect of IP performance has a small effect size. Lastly, in the relationship between technological innovation and financial performance, the method of measurement and publication type showed statistically significant moderating effects.

Effects of Death Education Programs among Korean Aged in the Convergence Era: A Systematic Review and Meta-Analysis (융복합 시대 한국 노인의 죽음교육 프로그램 효과: 체계적 문헌고찰 및 메타분석)

  • Kim, Hyunsim;Park, Seurk
    • Journal of Convergence for Information Technology
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    • v.12 no.5
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    • pp.71-82
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    • 2022
  • This study aimed to identify the effects of death education programs among Korean aged on death anxiety and attitudes toward death in the convergence era. The searched kew words were included aged, death education program, death anxiety, and attitudes to death in the research papers published in Korea. Finally, 11 studies were selected and the effect size was calculated. Death anxiety and death attitude were selected as dependent variables, and publication type, total duration of intervention, and frequency of intervention were selected as moderator variables. The total of 11 papers were selected to estimate the effect sizes of interventions. As a result, the overall effect size of the death education program for the aged was 1.07. The overall effect size showed death education program was able to lower death anxiety (Hedges' g=1.30, 95% Cl=0.80~1.80, p<.01) and improve attitudes to death (Hedges' g=0.93, 95% Cl=0.49~1.37, p<.01) compared with the no intervention group. In the moderator analysis to identify the cause of heterogeneity, significant results were found in the frequency of intervention. We propose a study that repeatedly verifies the effect of related studies in the future by providing the theoretical basis and basic data for the development of the death education program.

Effects of Exercise-Based Intervention Before and After Lung Cancer Surgery: A systematic review in pubmed database (허파암 수술 전과 후에 적용한 운동의 효과: PubMed 내 연구에 대한 체계적 문헌고찰)

  • Boram Oh;Heesu Kim;Sookyoung Park
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.2
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    • pp.23-35
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    • 2023
  • Purpose : Lung cancer induces a decrease in physical activity and a deterioration of respiratory ability. Exercise is an effective treatment to reduce side effects of anti-cancer treatments, also influence the survival and successful rehabilitation in lung cancer patients. However, there is insufficient evidence to show which period is the most effective to apply exercise for lung cancer patients. Therefore, this study was conducted to evaluate the efficacy of exercise-based interventions before and after surgery. Methods : Clinical trials (CTs) and randomized controlled trials (RCTs) reported in PubMed database were investigated. The trials investigated in this study were published for 10 years before August 20, 2022. The risk of bias was judged according to the Cochrane guideline. The materials included in this meta-analysis were 6-minute walk test (6MWT), pulmonary function, and quality of life (QOL). Results : 1 CT and 9 RCTs were selected in current study. In the meta-analysis, exercise increased 6MWT in preoperation (mean difference [MD] 29.49; 95 % confidence interval [CI] .99 to 57.99; p=.04; I2=0 %), 3 months postoperation (MD 54.97; 95 % CI 31.85 to 78.09; p<.001; I2=45 %) and 6 months postoperation (MD 85.59; 95 % CI 45.06 to 126.12; p<.001; I2=47 %). Exercise, also enhanced the lung function such as FEV1/FVC (%) in postoperation (MD 7.64; 95 % CI 6.26 to 9.02; p<.001; I2=19 %). Additionally, exercise improved QOL, such as preoperative EORTC-QLQ-C30-LC13 in mental function (MD 3.21; 95 % CI .64 to 5.79; p=.01; I2=0 %) and postoperative SF-36 in mental component summary (MD 9.24; 95 % CI 4.94 to 13.54; p<.001; I2=0%). Conclusion : These results indicate that exercise-based intervention can elevate the ability to exercise and the mental componentof QOL within 3 months.

The Effects of Music Interventions on High-risk Neonates in NICUs: Systematic Review and Meta-analysis (신생아집중치료실 고위험 신생아 대상 음악중재연구에 대한 체계적 문헌고찰 및 메타분석)

  • Kim, Hye Rang;Park, Hye Young
    • Journal of Music and Human Behavior
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    • v.20 no.2
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    • pp.115-142
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    • 2023
  • The purpose of this study was to analyze and evaluate music intervention research conducted with high-risk neonates in NICUs in both domestic and international settings. Seventeen music intervention studies were identified, and their characteristics, including type of music, music provider, and treatment frequency, and outcomes (i.e., neonatal vital signs) were reviewed and analyzed along with meta-analysis. For music interventions targeting high-risk neonates in NICUs, the effect sizes of the neonates' vital signs were classified as either medium or large. In addition, larger effect sizes were associated with a combination of live and recorded music, nonmusical therapists as the music providers, and treatment frequency of one to five sessions per week. These research findings verify the clinical value of music for high-risk neonates and provide insights into the selection of music elements, music delivery methods, and music providers in NICU music interventions.