• Title/Summary/Keyword: System of radiation protection

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Radiation Protection Effect of Selenium on the Rat's Prostate (흰쥐의 전립선에 대한 셀레늄(Se)의 방사선 방호효과)

  • Choi, Hyung-Seok;Choi, Jun-Hyeok;Jung, Do-Young;Kim, Jang-Oh;Shin, Ji-Hye;Kim, Joo-Hee;Min, Byung-In
    • Journal of radiological science and technology
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    • v.40 no.2
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    • pp.317-322
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    • 2017
  • High-tech medical equipment has increased the utilization of radiation in the medical field. As a result, research on radiation protection using natural materials has become an important social issue. Selenium is a natural substance that is highly expressed in prostate known that an essential role in prostate cells. Selenium was orally administered to Rat and irradiated with 10 Gy of radiation. Then, the prostate tissue w as used as a target organ for 1 day, 7 days and 21 days to investigate the radiation protection effect of selenium through changes of blood components, Superoxide Dismutase and histological changes. As a result, there was a significant protective effect of hematopoietic immune system(hemoglobin concentration, neutrophil, platelet) in the group irradiated with selenium(p<0.05). the observation of tissue changes selenium is an effective component to increase Superoxide Dismutase activity, and it was confirmed that it has an effect of inhibiting the expression of hypertrophy of prostate by irradiation. Therefore, it is considered that selenium can be utilized as a radioprotective agent by inducing prevention of prostate-related diseases.

The Site-Directed A184S Mutation in the HTH Domain of the Global Regulator IrrE Enhances Deinococcus radiodurans R1 Tolerance to UV Radiation and MMC Shock

  • Zhang, Chen;Zhou, Zhengfu;Zhang, Wei;Chen, Zhen;Song, Yuan;Lu, Wei;Lin, Min;Chen, Ming
    • Journal of Microbiology and Biotechnology
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    • v.25 no.12
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    • pp.2125-2134
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    • 2015
  • IrrE is a highly conserved global regulator in the Deinococcus genus and contributes to survival from high doses of UV radiation, ionizing radiation, and desiccation. Drad-IrrE and Dgob-IrrE from Deinococcus radiodurans and Deinococcus gobiensis I-0 each share 66% sequence identity. However, Dgob-IrrE showed a stronger protection phenotype against UV radiation than Drad-IrrE in the D. radiodurans irrE-deletion mutant (ΔirrE), which may be due to amino acid residues differences around the DNA-binding HTH domain. Site-directed mutagenesis was used to generate a Drad-IrrE A184S single mutant, which has been characterized and compared with the ΔirrE mutant complemented strain with Drad-irrE, designated ΔirrE-E. The effects of the A184S mutation following UV radiation and mitomycin C (MMC) shock were determined. The A184S mutant displayed significantly increased resistance to UV radiation and MMC shock. The corresponding A184 site in Dgob-IrrE was inversely mutated, generating the S131A mutant, which exhibited a loss of resistance against UV radiation, MMC shock, and desiccation. qPCR analysis revealed that critical genes in the DNA repair system, such as recA, pprA, uvrA, and ddrB, were remarkably induced after UV radiation and MMC shock in the ΔirrE-IE and A184S mutants. These data suggested that A184S improves the ability against UV radiation and MMC shock, providing new insights into the modification of IrrE. We speculated that the serine residue may determine the efficiency of DNA binding, leading to the increased expression of IrrE-dependent genes important for protection against DNA damage.

Measurement and Analyses of Radiation -Assessment of Defected Fuel by Analysis of Reactor Coolant Activities- (방사선 측정 및 해석 연구 -원자로 냉각수중의 방사능해석에 의한 결함핵연료봉의 평가-)

  • Yang, Jae-Choon;Oh, Hi-Peel;Jun, Jae-Shik;Lee, Ho-Yon;Oh, Heon-Jin;Chung, Moon-Kyu;Park, Hae-Yong
    • Journal of Radiation Protection and Research
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    • v.11 no.2
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    • pp.139-145
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    • 1986
  • An improved mothod of assessing fuel status by analyzsis of the fission product in the reactor coolant system is proposed. The release mechanism of specific fission products is established for determination of the coefficients in the equations which relate the radioactivities with the amount of defected fuel. Knock-out and migration models are employed in the formulation of the release mechanism. The influence of the tramp uranium is quantified. Sample calculations were made for KNU 1 reactor system using the I-131 and I-133 concentrations in the primary coolant. The estimated number of defected fuel pins in the third and sixth cycles appeared to be $9.34{\pm}1.13\;and\;0.294{\pm}0.092$, respectively.

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Formation of Ultra fine Particle by the Polonium-218 Ions under Different Humidity Conditions (다른 습도조건하에서 Po-218 이온들의 극소입자형성에 관한 연구)

  • Yoon, Suk-Chul;Ha, Chung-Woo
    • Journal of Radiation Protection and Research
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    • v.17 no.1
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    • pp.1-10
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    • 1992
  • A number of investigators have reported the formation of the radiolytic ultrafine particles produced by the interaction of ionizing radiation with water vapor. Previous studies have suggested that a very high localized concentration of the OH radical produced by the radiolysis of water can react with trace gas like organic vapors and produce lower vapor pressure compounds that can then nucleate. In order to determine water vapor dependence of the active, positively charged, first radon daughter(Po-218), an experiment was conducted using a well-controlled radon chamber. The activity size distribution of the radon daughter in the range of 0.5-100nm was measured using the parallel graded wire screens system. Measurements were taken for different relative humidity. The resultant activity size distributions were analyzed. The addition of water vapor to the radon carrier gases resulted in the formation of ultrafine particles by OH radicals formed by radon radiolysis. It may be due to the neutralization of charged Po-218 ion with water vapor through the radio lysis.

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Cross Talk Experiment with Two-element CdTe Detector and Collimator for BNCT-SPECT

  • Manabe, Masanobu;Ohya, Ryosuke;Saraue, Nobuhide;Sato, Fuminobu;Murata, Isao
    • Journal of Radiation Protection and Research
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    • v.41 no.4
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    • pp.328-332
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    • 2016
  • Background: Boron Neutron Capture Therapy (BNCT) is a new radiation therapy. In BNCT, there exists some very critical problems that should be solved. One of the severest problems is that the treatment effect cannot be known during BNCT in real time. We are now developing a SPECT (single photon emission computed tomography) system (BNCT-SPECT), with a cadmium telluride (CdTe) semiconductor detector. BNCT-SPECT can obtain the BNCT treatment effect by measuring 478 keV gamma-rays emitted from the excited state of $^7Li$ nucleus created by $^{10}B(n,{\alpha})$ $^7Li$ reaction. In the previous studies, we investigated the feasibility of the BNCT-SPECT system. As a result, the S/N ratio did not meet the criterion of S/N > 1 because deterioration of the S/N ratio occurred caused by the influence of Compton scattering especially due to capture gamma-rays of hydrogen. Materials and Methods: We thus produced an arrayed detector with two CdTe crystals to test cross talk phenomenon and to examine an anti-coincidence detection possibility. For more precise analysis for the anti-coincidence detection, we designed and made a collimator having a similar performance to the real BNCT-SPECT. Results and Discussion: We carried out experiments with the collimator to examine the effect of cross talk of scattering gamma-rays between CdTe elements more practically. As a result of measurement the coincidence events were successfully extracted. Conclusion: We are now planning to carry out evaluation of coincidence rate from the measurement and comparison of it with the numerical calculations.

Development of the ZnS(Ag)/BC-408 phoswich detector for monitoring radioactive contamination inside pipes (배관 내부 방사능 오염도 측정용 ZnS(Ag)/BC-408 phoswich 검출기 개발)

  • Kim, Gye-Hong;Park, Chan-Hee;Jung, Chong-Hun;Lee, Kune-Woo;Seo, Bum-Kyoung
    • Journal of Radiation Protection and Research
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    • v.31 no.3
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    • pp.123-128
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    • 2006
  • A small radiation detection system is necessary for the direct characterization of alpha/beta-ray contamination inside pipes generated during the decommission of a nuclear facility. In this work, the new type phoswich detector consisting of the ZnS(Ag) and plastic scintillator for ${\alpha}/{\beta}$ simultaneous counting was designed as part of a development of a equipment capable of monitoring radiological contamination inside pipes. The optimum counting conditions in dimensions of scintillator and a detection system were experimentally confirmed and a performance of alpha/beta-ray discrimination was evaluated. As a result, optimum conditions of a detector suitable for monitoring radiological contamination inside pipes and a feasibility of application to pipe-inside were confirmed.

A Study on the Angular Dependence of the PB-3 Dosimeter Using Teledyne 9150 TLD Reader System (열형광선량계(도시메터타입 : PB-3)의 방향의존성에 관한 연구)

  • Son, Jung-Kwon;Kim, Jong-Kyung;Yoon, Suk-Chul
    • Journal of Radiation Protection and Research
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    • v.19 no.3
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    • pp.189-198
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    • 1994
  • An angular dependence experiment was made and a performance test of the Teledyne dosimetry system was done in accordance with the ANSI N13.11-1992. The angular dependence experiment was performed with $^{137}Cs$ and low energy X-ray beam. Teledyne dosimetry system performed well at the $0^{\circ}$ angle of incidence for all dosimeters in both vertical and horizontal irradiations. It would have easily passed the 0.5 tolerance limit. But the dosimetry system was not performed well at the ${\pm}60^{\circ}$ angle of incidence for low energy X-ray beam. The accuracy for $^{137}Cs$ beam at all angles of incidence was within the 0.5 tolerance limit. Therefore performance of the dosimetry system could be considered acceptable in case that the dosimeter is irradiated to $^{137}Cs$ beam. However, it could not be acceptable for the dosimeter irradiated to low energy X-ray, especially at more than ${\pm}40^{\circ}$

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Study on Research for Reducing Radiation Dose of Head and Neck for Cephalometric Radiography System (두부규격방사선촬영장치의 두경부 피폭 저감에 대한 연구)

  • OH, Yoonjin;Shin, Jae-won;Lee, Samyol
    • Journal of the Korean Society of Radiology
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    • v.10 no.5
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    • pp.291-298
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    • 2016
  • Recently, the interest in the orthodontic treatment for children is increased by a rise in national income level. The number of cephalometric radiography that could diagnose a malocclusion and malposition between teeth and jawbone increased. It required attention to radiation exposure, because the subject of dental examination is children which are more sensitive to radiation and the head and neck, the object of that include radiation sensitive organ such as the thyroid, bone marrow, eyes, salivary gland, and so on. In this study, we measured two-dimensional dose distribution in cephalometric radiography system (VATEC Pax-400C) using Agfa CP-G Plus film and MagicMax Dosimeter, and calculated radiation organ dose of head and neck through MCNPX simulation. And then we designed a radiation protective device to decrease radiation dose. The dose distribution of the cephalometric radiography system irradiated the head and neck overall as well as the oral and maxillofacial parts. The radiation organ dose calculated that thyroid, oesophagus and eyes are irradiated high, and the radiation organ dose decreased about 70 ~ 80% by the application of the radiation protective device. The results of this study will be used construction of database for dental radiation exposure and research of reducing radiation dose.

A Study on Scale Busting and Preventing Effect of Coating Ceramic Ball (코팅 세라믹볼의 방청효과에 관한 연구)

  • 하윤식;김학용;김수진;백우현
    • Journal of Environmental Science International
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    • v.11 no.10
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    • pp.1117-1123
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    • 2002
  • Coating ceramic balls activate water molecular in water as radiate far-infrared radiation of high efficiency, and then prevent formation of scale and corrosion of pipe. Therefore, but only keep away drop of heat exchange efficiency of boiler, not also remove formed scale. As a result, pipe of boiler has clean and has form thin protection film in inner of pipe. Also, the water treated by rust preventing system using the ceramic balls, that is harmless, tasteless, odorless, and non-toxicity in the human body, and it can use drinking water. This rust preventing system can save energy and protect environment.

Nuclide Identification of Gamma Ray Energy Peaks from an Air Sample for the Emergency Radiation Monitoring (비상시 환경방사능 모니터링을 위한 공기부유진 시료의 감마선에너지 스펙트럼에 대한 핵종판별)

  • Byun, Jong-In;Yoon, Seok-Won;Choi, Hee-Yeoul;Yim, Seong-A;Lee, Dong-Myung;Yun, Ju-Yong
    • Journal of Radiation Protection and Research
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    • v.34 no.4
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    • pp.170-175
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    • 2009
  • For the emergency radiation monitoring using gamma spectrometry, we should sufficiently survey the background spectra as environmental samples with systematic nuclide identification method. In this study, we obtained the gamma ray energy spectrum using a HPGe gamma spectrometry system from an air sample. And we identified nuclide of the gamma ray energy peaks in the spectrum using two methods -1) Half life calculation and 2) survey for cascade coincidence summing peaks using nuclear data. As the results, we produced the nuclide identification results for the air sample.