• Mycobiology
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• v.48 no.5
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• pp.410-417
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• 2020

Fungal ecological interactions play a key role in structuring community assemblages. These associations may involve both antagonistic and synergistic relationships, which are commonly influenced by abiotic factors such as nutrient conditions. However, information for extreme, oligotrophic systems remain poor. Herein, interactions among key members of the aquatic transient fungal community (Aspergillus niger, Cladosporium sp., and Coprinellus micaceus) of a low-nutrient freshwater system in the Cuatro Ci enegas Basin, Mexico were studied. Pairwise interaction bioassays were explored in vitro under different nutrient conditions, including carbohydrates-rich, carbohydrates and amino peptides-rich, and low nutrients. Our results indicated that antagonistic patterns prevail among the studied taxa. However, nutrient-dependent changes were observed in Cladosporium sp. shifting to synergy under carbohydrates-rich conditions, suggesting changes in the fungal community composition as a result of nutrient enrichment. Remarkably, our findings contrast with previous work demonstrating mainly synergistic interactions between our tested fungal isolates and co-occurring autochthonous bacteria (Aeromonas spp. and Vibrio sp.) under low-nutrient conditions. This observation may indicate that bacteria and fungi exhibit distinct community-level responses, driven by nutrient conditions. This contributes to the knowledge of fungal community dynamics and interspecific interactions in an oligotrophic ecosystem, highlighting the relevance of nutrient-based shifts and antagonistic interactions in ecosystem dynamics.

• Journal of Communications and Networks
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• v.17 no.2
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• pp.100-109
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• 2015

Mobile phone carriers face challenges from three synergistic dimensions: Wireless, social, and mobile. Despite significant advances that have been made about social networks and human mobility, respectively, our knowledge about the interplay between two layers remains largely limited, partly due to the difficulty in obtaining large-scale datasets that could offer at the same time social and mobile information across a substantial population over an extended period of time. In this paper, we take advantage of a massive, longitudinal mobile phone dataset that consists of human mobility and social network information simultaneously, allowing us to explore the impact of human mobility patterns on the underlying social network. We find that human mobility plays an important role in shaping both local and global structural properties of social network. In contrast to the lack of scale in social networks and human movements, we discovered a characteristic distance in physical space between 10 and 20 km that impacts both local clustering and modular structure in social network. We also find a surprising distinction in trajectory overlap that segments social ties into two categories. Our results are of fundamental relevance to quantitative studies of human behavior, and could serve as the basis of anchoring potential theoretical models of human behavior and building and developing new applications using social and mobile technologies.

• Safety and Health at Work
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• v.2 no.2
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• pp.97-104
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• 2011

N,N-Dimethylformamide (DMF) is globally used as an organic solvent in the production of synthetic leather and resins because of its low volatility, making it an attractive industrial material. Despite its excellent property as a chemical solvent, utilization of DMF is somewhat controversial nowadays due to its hazardous effects on exposed workers in work places. Many toxification cases are being reported globally and the number of cases of liver damage is still increasing in developing countries. On account of this, a series of epidemiologic surveys are being conducted to understand the degrees of liver damage caused by DMF exposure. Furthermore, many investigations have been performed to clarify the mechanism of DMF-induced liver toxicity using both human and experimental animal models. This review summarizes the current occupational cases reported on liver damage from workers exposed to DMF in industrial work places and the research results that account for DMF-induced liver failure and possible carcinogenesis. The findings reviewed here show the synergistic toxicity of DMF exposure with other toxicants, which might occur through complicated but distinct mechanisms, which may extend our knowledge for establishing risk assessments of DMF exposure in industrial work places.

• Knowledge Management Research
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• v.25 no.1
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• pp.67-88
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• 2024

Smart tourism aims to maximize the utilization of local tourism resources, effectively manages cities and contributes to improving communication and quality of life between tourists and residents. Therefore, smart tourism emphasizes synergistic collaboration, considering both residents and tourists. This study explores smart tourism interaction and roles in enhancing regional competitiveness. By conducting thorough examination, focusing on integrating the four key elements of smart tourism city (smart experience, smart convenience, smart accessibility, and smart platform) with local residents, local businesses, regional resources, and ecosystem to foster positive synergies, Incheon smart tourism city project was employed as a single case study design. Research results indicate that the collaborative model of a smart tourism city positively impacts service satisfaction and strengthens regional tourism competitiveness. Building upon these results, this study aims to contribute to the development of smart tourism cities by proposing directions for future development and emphasizing the enhancement of regional competitiveness through the integration of smart technology and local tourism.

• Journal of Sasang Constitutional Medicine
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• v.25 no.4
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• pp.432-441
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• 2013

Objectives Despite the treatment with antibiotics, patients with sepsis has a high mortality (80%) in the underlying disease group. The aim of this study was to report the improvement of septic condition of the cholangiocarcinoma patient after the treatment with Handayeolso-tang, Fel Tauri, and antibiotics. Methods We retrospectively reviewed the medical records. The patient's subjective symptoms such as chilling and abdominal pain were evaluated by NRS and the performance status was evaluated by ECOG. This case was literally compared with relevant published studies on prognosis of sepsis. Results Despite poor prognostic factor(MEDS score 18), the patient's symptoms such as fever, chilling, abdominal pain, and diarrhea and ECOG(Eastern Cooperative Oncology Group) improved. The patient was hemodynamically stabilized on 3rd day from the treatment, and her laboratory test results were normalized on 7th day. Conclusions A female patient of metastatic cholangiocarcinoma came to the hospital for cholangitis, later causing septic shock. Both her symptoms and laboratory tests showed significant improvement after the treatment of antibiotics, Handayeolso-tang and Fel Tauri. To our knowledge, this is the first case reporting the synergistic combination of Korean oriental medicine and Western medicine approaching to sepsis.

• Journal of Digital Convergence
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• v.10 no.2
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• pp.47-53
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• 2012

Economic crisis, efforts to overcome the digital content industry development at home and abroad have been racing in the country's future lies in the digital content industry. Therefore, the digital content industry through vision, model identification knowledge-based global digital content market-based deployment is required. For research purposes the digital content industry to derive an alternative to national industrial development that will lay the groundwork. The deployment order for the first digital content industry, SWOT analysis performed to derive the Korean-specific model. As a result, measures based on the advancement of digital content industry as a long-term vision and specific goals are presented as staged. The age of convergence of the u-media content markets in government, corporations, consumers, and these form the structure of a virtuous cycle distribution systems for energy by being active, synergistic effects are obtained. Above all, based on the content industry to secure internal and external growth is key. Vision of the digital content, the growth momentum of the national social development policies to be used as a role model by changing the way a series of courses is required.

• Journal of Haehwa Medicine
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• v.18 no.2
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• pp.47-62
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• 2009

Atopic dermatitis induced NC/Nga mice were used to investigate the efficacy of HYT on the recovery of dermatitic symptoms by how HYT influenced the immune related factors. The results are as below: 1. Compared to the control, HYT treated group showed recovery of atopic dermatitis by the naked eye observation, and significant reduction of dermatits index was observed after 14 weeks. 2. HYT treated group showed significant decrease of the ratio of CCR3+, B220+/IgE+, and Gr-1+/CD11b+ immune cells in dorsal skin by 40.5%, 34.2%, and 48.1%, respectively. 3. HYT treated group showed increase in the ratio of CD19+ immune cells within PBMC by 10.8%, as well as decrease in CD3+, CD3+/CD69+, NKT+ ratios by 5.3%, 35.2%, and 44.9%, respectively. 4. HYT treated group showed increase in the expression of IFN-$\gamma$ in serum by 589.3%, whereas the expression of IL-4, IL-5, IL-6, IL-13, TNF-$\alpha$, MCP-1 and RANTES were decreased by 31.4%, 82.1%, 97.1%, 39.5%, 83.7%, 26.1%, 48.6%, respectively. A 47.2% decrease in IgE expression was also observed. The results above strongly supported the improvement of atopic dermatitis by HYT treatment through immune modulation. Further studies on the synergistic effect of each ingredients of HYT and therapeutic effects according to the dosage of each ingredient should be followed for clinical applications. This work was (partly) supported by the RIC program of MKE(Ministry of Knowledge Economy) in Daejeon University.

• Herbal Formula Science
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• v.10 no.2
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• pp.1-4
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• 2002

The development of Korean Oriental medicine is based upon the accumulation of experience and knowledge gathered over the centuries. The approaches taken are holistic and empirical. There is a need to understand their actions at molecular levels with more rational, objective and scientific studies. Today it appears that Chronic and age-associated diceases may be multifactorial and hence more complex. A different approach may be required. One claimed usage of Korean Oriental medicine is for the treatment and prevention of chronic and age-associated illnesses. Some of the botanical formulas used for this purpose were discovered thousands of years ago and continue to be used today. There are indications that these formulas may indeed be helpful in the treatment or prevention of chronic diseases. This multi-component medicine could not only be very useful meeting the unmet clinical needs but for defining a more synergistic therapy that supports and maintains the bodies natural curative abilities. The potential usefulness of Korean Oriental medicine embodies the belief of maintaining healthy homeostasis of the body through the proper balance of a mixture of chemical at different organs or tissues. This concept is different from western medicine and implies that multiple compounds may act on multiple mechanisms of action to maintain the balance of the complex web of biology. This is very important in view of sciences current direction to integrate fragmented information to develop future medicines. The western and eastern approaches to human health and disease are complementary to each other. The best approach in developing future medicines is to integrate both approaches.

• Korean Journal of Soil Science and Fertilizer
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• v.44 no.4
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• pp.637-649
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• 2011

Soil microorganisms play a major role in improving soil fertility and plant health. Symbiotic arbuscular mycorrhizal fungi (AMF) form a key component of the soil microbial populations. AMF form a mutualistic association with the host plant and exert a positive influence on its growth and nutrient uptake. The establishment of mycorrhizal symbioses with the host plant can positively be influenced by plant growth promoting rhizobacteria through various mechanisms such as increased spore germination and hyphal permeability in plant roots. Though there are evidences that combined interactions between AMF and PGPR can promote the plant growth however mechanisms of these interactions are poorly understood. Better understanding of the interactions between AMF and other microorganisms is necessary for maintaining soil fertility and enhancing crop production. This paper reviews current knowledge concerning the interactions between AMF and PGPR with plants and discusses on enhanced nutrient availability, biocontrol, abiotic stress tolerance and phytoremediation in sustainable agriculture.

• Journal of Korea Multimedia Society
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• v.3 no.2
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• pp.201-208
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• 2000

In this paper We describe an algorithm which is devised for 4he partition o# the input space and the generation of fuzzy rules by the fuzzy entropy and tested with the time series prediction problem using Mackey-Glass chaotic time series. This method divides the input space into several fuzzy regions and assigns a degree of each of the generated rules for the partitioned subspaces from the given data using the Shannon function and fuzzy entropy function generating the optimal knowledge base without the irrelevant rules. In this scheme the basic idea of the fuzzy neural network is to realize the fuzzy rules base and the process of reasoning by neural network and to make the corresponding parameters of the fuzzy control rules be adapted by the steepest descent algorithm. The Proposed algorithm has been naturally derived by means of the synergistic combination of the approximative approach and the descriptive approach. Each output of the rule's consequences has expressed with its connection weights in order to minimize the system parameters and reduce its complexities.