• Title/Summary/Keyword: Symptom severity

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The Clinical Significance of Periodic Limb Movements During Sleep in Various Sleep Disorders (다양한 수면장애의 주기성사지운동증의 임상적 의의)

  • So-Jin Lee
    • Sleep Medicine and Psychophysiology
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    • v.30 no.1
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    • pp.9-12
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    • 2023
  • Periodic limb movements during sleep (PLMS) are prevalent in various sleep disorders, such as restless legs syndrome (RLS), periodic limb movements disorder, obstructive sleep apnea (OSA), REM sleep behavior disorder (RBD), and narcolepsy. PLMS has been hypothesized to be related to the decline of dopaminergic transmission. In RLS, PLMS is suggested to be related to iron deficiency and symptom severity. PLMD is a rare sleep disorder, and the role of PLMS in PLMD has not been clearly investigated yet. PLMS in OSA, which remain after proper PAP therapy, may need further management. The clinical relevance of PLMS in RBD and narcolepsy have not been investigated thoroughly and need further studies. Whether PLMS are to be considered as a mere symptom of individual sleep disorders or not can be elucidated through studies investigating the efficacy of therapeutic approaches to reduce PLMS in various sleep disorders.

One Case Report of Chronic Motor Tic Disorder Patient with Extreme Headache and Insomnia. (극심한 두통과 불면을 호소하는 만성 운동 틱 장애 환자1례 보고)

  • Kim, Ja-Young;Kang, Hyun-Sun;Lee, Jin-Hwan;Sung, Woo-Yong;Jeong, Da-Un
    • Journal of Oriental Neuropsychiatry
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    • v.19 no.3
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    • pp.219-229
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    • 2008
  • Tics are sudden, painless, nonrhythmic behaviors that are either motor or vocal. As to DSM- VI diagnostic criteria, chronic tic disorder is either single or multiple motor or phonic tics, but not both, which are present for more than a year. In this case, a male patient was diagnosed tics disorder at 8 years old. He has suffered for 15 years and his symptom was simple motor tics of neck, both arms and both legs, not vocal tics. So we diagnosed him as the chronic tic disorder. The severity score headache was assessed using the Visual Analog Scales. The severity score tics was assessed at baseline using the Yale Global Tic Severity Scale (YGTSS) and we compared score of before with after treatment. We treated him with oriental medication( herbal medicine, acupuncture, cry cupping) and progressive muscle relaxation. After this treatment, chronic insomnia and extreme headache were disappeard and the symptoms of tics were mildly decreased.

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Alteration of Gas Exchange in Rice Leaves Infected with Magnaporthe grisea

  • Yun, Sung-Chul;Kim, Pan-Gi;Park, Eun-Woo
    • The Plant Pathology Journal
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    • v.16 no.5
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    • pp.257-263
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    • 2000
  • Infection with rice blast fungus (Magnaporthe grisea) significantly reduced foliar net photosynthesis (A) of rice cultivars: Ilpoom, Hwasung, and Choochung in greenhouse experiments. By measuring the amount of diseased leaf area with a computer image analysis system, the relation between disease severity (DS) and net photosynthetic rate was curvilinearly correlated (r=0.679). Diseased leaves with 35% blast symptom can be predicted to have a 50% reduction of photosynthesis. The disease severity was linearly correlated (r=0.478) with total chlorophyll (chlorophyll a and chlorophyll b) per unit leaf area(TC). Light use efficiency was reduced by the fungal infection according to the light response curves. However, dark respiration (Rd) did not change after the fungal infection (p=0.526). Since the percent of reduction in photosynthesis greatly exceeded the percent of leaf area covered by blast lesions, loss of photosynthetic tissue on an area basis could not by itself account for the reduced photosynthesis. Quantitative photosynthetic reduction can be partially explained by decreasing TC, but cannot be explained by decreasing Rd. By photosynthesis (A)-internal CO$_2$ concentration (C$_i$ curve analysis, it was suggested that the fungal infection reduced ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) activity, ribulose-1,5-bisphosphate (RuBP) regeneration, and inorganic phosphate regeneration. Thus, the reduction of photosynthesis by blast infection was associated with decreased TC and biochemical capacity, which comprises all carbon metabolism after CO$_2$ enters through the stomata.

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PTSD Symptoms in Elementary School Children After Typhoon Rusa

  • Lee, In-Sook;Ha, Yang-Sook;Kim, Yoon-A;Kwon, Yong-Hee
    • Journal of Korean Academy of Nursing
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    • v.34 no.4
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    • pp.636-645
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    • 2004
  • Purpose. A natural disaster negatively affects children's emotional and behavioral adjustment. The purpose of this paper was to examine the prevalence, symptoms, and correlates of PTSD after the occurrence of Typhoon Rusa. Method. 261 elementary school children living in Kimcheon, which was a devastated rural area in South Korea by Typhoon Rusa, were selected. Data were collected 4 months after the disaster using the PTSD Reaction Index categories recommended by Frederick, severity of PTSD. Results. 12.3% of the children had either moderate or severe PTSD symptoms; 22.7% reported mild symptoms; and the remaining 65% had sub-clinical symptoms of PTSD. The most frequent symptom was recurrenct fear(67.0%). 13% to 17.2% of children exhibited difficulty in concentration, sleep disturbance, and guilt feeling. The regression model of severity of PTSD was composed of the level of exposure to traumatic experiences, grade in school, gender, negative coping style, and social support, and explained 34.3% for PTSD symptoms. Exposure to traumatic experiences was the strongest factor of all predictors. Conclusion. Emotional support from friends and coping style were correlated with PTSD severity. School-based interventions that emphasizes coping with disaster related problems and problem-solving may prove to be useful, and may aid in building close and supportive ties with teachers, classmates, and friends.

Predictors of outcomes after the trans-obturator tape procedure in females with equal severity for stress and urge mixed urinary incontinence

  • Young-Joo Kim
    • Journal of Medicine and Life Science
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    • v.20 no.4
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    • pp.166-171
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    • 2023
  • Mixed urinary incontinence (UI) is common in women. This study aimed to assess the efficacy of anti-incontinence surgery in female patients with equally severe stress UI (SUI) and urge UI (UUI). All patients had equal severity of SUI and UUI. The postoperative cure rate was categorized into the cure group (CG) and failure group (FG). Postoperative satisfaction was categorized into the satisfaction group (SG) and the dissatisfaction group (DG). Statistical significance was set at P<0.05. Ninety patients (SG, 73.3%; DG, 26.7%; CG, 93.3%; FG, 6.7%) were included in the study. In the univariate analysis, body mass index (BMI), total bladder capacity, and overactive bladder symptom score (OABSS) were significantly different between the SG and DG groups. Peak urinary flow, Valsalva leak point pressure (VLPP), and OABSS were significantly different between the CG and FG groups. In the multivariate analysis, OABSS (P=0.001) and BMI (P=0.032) were independent predictors of postoperative satisfaction. VLPP (P=0.023) was the only independent factor associated with the postoperative cure rate. In equal severity of SUI and UUI, VLPP was found to be the only independent factor associated with postoperative cure rates. Higher VLPP values were associated with higher cure rates. BMI and OABSS were identified as independent predictors of postoperative satisfaction, with lower BMI and OABSS associated with higher postoperative satisfaction.

Effects of Cheongyoung-tang on CHT-Induced Brain Edema and Neurological Disturbance Symptom in Rats (청영탕이 CHT로 유발된 백서의 뇌부종 및 신경장애 증상에 미치는 영향)

  • Cheong Sang Su;Lee Sang Kwan;Sung Kang Keyng
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.5
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    • pp.948-954
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    • 2002
  • This study was carried out to evaluate Effects of Cheongyoung-tang on CHT-Induced Brain Edema and Neurological Disturbance Symptom in Rats. we make a comparative study of the such parameters as neurological severity score(NSS) and changes in water content, lactate, glucose and hematological substance. 1. ΔNSS increased in CYT1 and CYT2 as compared with the control group, which showed no efficacy. 2. In water content of both hemispheres, CYT1 and CYT2 as compared with the control group have no difference. 3. Water content of the left hemisphere decreased in CYT1 and CYT2 as compared with the control group. 4. The lactate level in serum decreased in CYT1 and CYT2 as compared with the control group. 5. In hematological changes, RBC, PLT and MCHC increased in CYT1 and CYT2 as compared with the control group, but MCV decreased. According to these results, CYT has an effect on CHT-induced brain edema and neurological symptom.

A Study on the Relationship with Nicotine Dependence and Mental Health -Focusing on SCL-90-R (Symptom Checklist-90-Revision)- (니코틴 의존도와 정신 건강 수준의 연관성에 대한 조사 연구 -간이 정신진단 검사 중심으로-)

  • Kang, Hee-Chul
    • Journal of Oriental Neuropsychiatry
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    • v.25 no.1
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    • pp.55-62
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    • 2014
  • Objectives: The purpose of this study is to investigate the relationship of nicotine dependence and mental health. Methods: The subjects of this study were 153 male smokers in their 20s, 30s, 40s and 50s who visited Wonmi Public Health Center. They were evaluated with Fagerstorm's test for nicotine dependence (FTND) and Symptom Checklist-90-Revision (SCL-90-R). Using the FTND score, the participants were divided into three groups; mild nicotine dependent group, moderate group and severe group. Results: In the SCL-90-R score, there were statistically significant differences in the characteristics of Somatization, Obsessive-Compulsive, Interpersonal Sensitivity, Depression, Global Severity Index (GSI) and Positive Symptom Test (PST) among the three groups. Comparing the values of FTND and the amounts of Daily Smoking to the values of Somatization, Obsessive-Compulsive, Interpersonal Sensitivity, Depression and GSI in this study resulted in positive correlations, thereby demonstrating a statistical significance. Conclusions: The above results suggest that there are significant relations between nicotine dependence and the level of mental health. These results can be used for planning the smoking cessation program and mental health promoting program based on Korean traditional medicine.

A Study on the Comparison of Video Display Terminal(VDT) Subjective Symptoms for Computer-addicted and Non-addicted Adolescents (컴퓨터 중독과 비중독 청소년의 컴퓨터 단말기(VDT) 자각증상 비교연구)

  • Kim, Jin-Yi;Cho, Kyoul-Ja
    • Child Health Nursing Research
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    • v.11 no.2
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    • pp.159-166
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    • 2005
  • Purpose: The purpose of this study was to compare subjective symptoms of VDT between computer-addicted and non-addicted adolescents. Method: A descriptive survey design was used and 646 students in one middle and two high schools were selected as participants. Result: The VDT subjective symptoms and degree of severity differed according to whether the students were computer-addicted or not, and in all symptoms, general, musculoskeletal, eye and mental, the mean score for subjective symptoms was higher in the addicted group than in the non-addicted group. The score for VDT subjective symptoms was highest in the addicted group for girls and students who were not healthy. The most frequent physical symptom reported by students who visited the school health room for a health problem after using the computer was headache. The most frequent type of treatment at the school health room was treatment of the symptom. Conclusions: This study suggests that students must acquire correct habits in computer use and be careful not to be addicted to the computer in order to avoid VDT syndrome. For this, educational authorities should develop computer-related health education programs and start the programs from the lower grades of elementary school.

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A Subpopulation of RNA3 of Cucumber mosaic virus Quasispecies

  • Park, Seung-Kook;Park, Sun-Hee;Yoon, Ju-Yeon;Park, Jang-Kyung;Ryu, Ki-Hyun
    • The Plant Pathology Journal
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    • v.19 no.4
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    • pp.210-216
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    • 2003
  • This study examined the existence of genetically diverse population of Cucumber mosaic virus (CMV), known as quasispecies, from lily, Nicotiana benthamiana and from purified virions. Based on the conserved sequences of CMV lily isolates in intergenic region (IR) on RNA3, the genetic variation of IR from three different sources was investigated by a specific restriction endonuclease hydrolysis of amplified reverse transcription-polymerase chain reaction (RT-PCR) products using virus-specific primers, and was compared with IR sequences. The IR nucleotide sequences of CMV lily isolates were highly conserved, however, quasispecies was detected from all three sources in low level, containing sub-populations of RNA3. These subpopulations of RNA3 were inoculated onto zucchini squash by in vitro transcripts from corresponding full-length cDNA clones together with Eny RNA1 and 2 transcripts. The systemic symptom of zucchini plants infected by these quasispecies was chlorotic spotting, which was milder than severe mosaic and stunt symptom caused by Eny-CMV. The severity of symptom was correlated with RNA accumulation of viruses. These results suggest that the genome of CMV lily isolates consists of quasispecies populations.

The Effectiveness of Acupuncture for Fatigue Severity in Lung Cancer Patients: Pilot Study (침치료가 폐암 환자의 피로도에 미치는 영향: Pilot Study)

  • Hyun, Dae-Sung;Kim, Jong-Dae;Kwon, Hyo-Jung;Jung, Hyun-Jung
    • Korean Journal of Acupuncture
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    • v.29 no.4
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    • pp.623-633
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    • 2012
  • Objectives : Fatigue is a common and distressing symptom that is a concern for cancer patients. It has a decisive effect on quality of life. The purpose of this study was to examine the feasibility of clinical trial to evaluate of efficacy and safety of acupuncture on cancer related fatigue of lung cancer patients. Methods : Total lung cancer 9 patients complained of fatigue were treated by acupuncture twice a week for four weeks(8 times in total). Evaluation of the severity of fatigue was measured by FSS(Fatigue Severity Score). In visit 1, 10, we checked FSS. For check safety of acupuncture treatment, we did blood test. Results : After 4 weeks of acupuncture treatment, the FSS was significantly decreased from $4.92{\pm}1.06$ to $3.74{\pm}1.37$(p=0.008). And the level of hemoglobin was significantly increased from 10.87 g/dl to 12.01 g/dl(p=0.014). No other lab measures indicated any significant differences between before and after acupuncture treatment. Conclusions : This study suggests that acupuncture treatment will be beneficial for lung cancer patients to improve the fatigue severity. And acupuncture treatment is safe method for lung cancer patients. A large-scale study to confirm efficacy and safety of acupuncture is needed.