Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effects of Cheongyoung-tang on CHT-Induced Brain Edema and Neurological Disturbance Symptom in Rats

청영탕이 CHT로 유발된 백서의 뇌부종 및 신경장애 증상에 미치는 영향

  • Cheong Sang Su (Department of Cardiovascular Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Lee Sang Kwan (Department of Cardiovascular Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Sung Kang Keyng (Department of Cardiovascular Internal Medicine, College of Oriental Medicine, Wonkwang University)
  • 정상수 (원광대학교 한의과대학 심계내과학교실) ;
  • 이상관 (원광대학교 한의과대학 심계내과학교실) ;
  • 성강경 (원광대학교 한의과대학 심계내과학교실)
  • Published : 2002.10.01
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Abstract

This study was carried out to evaluate Effects of Cheongyoung-tang on CHT-Induced Brain Edema and Neurological Disturbance Symptom in Rats. we make a comparative study of the such parameters as neurological severity score(NSS) and changes in water content, lactate, glucose and hematological substance. 1. ΔNSS increased in CYT1 and CYT2 as compared with the control group, which showed no efficacy. 2. In water content of both hemispheres, CYT1 and CYT2 as compared with the control group have no difference. 3. Water content of the left hemisphere decreased in CYT1 and CYT2 as compared with the control group. 4. The lactate level in serum decreased in CYT1 and CYT2 as compared with the control group. 5. In hematological changes, RBC, PLT and MCHC increased in CYT1 and CYT2 as compared with the control group, but MCV decreased. According to these results, CYT has an effect on CHT-induced brain edema and neurological symptom.

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