• Title/Summary/Keyword: Symptom indicator

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Relationship of between blood lead level and lead related symptoms in low level lead exposure (저농도 연폭로에서 혈중 연농도와 자각증상과의 관계)

  • Hwang, Kyu-Yoon;Ahn, Jae-Eog;Ahn, Kyu-Dong;Lee, Byung-Kook;Kim, Joung-Soon
    • Journal of Preventive Medicine and Public Health
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    • v.24 no.2 s.34
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    • pp.181-194
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    • 1991
  • This study intended to obtain an useful information on the prevalence of subjective symptoms, and to clarify the interrelationships between blood lead and lead related symptoms in low level lead exposure. The 93 male workers exposed to lead and 56 male nonexposed workers were examined for their blood lead(PBB), Zinc-protoporphy(ZPP), hemoglobin(HB) and personnal history, and completed 15 questionnaires related to symptoms of lead absorption : also measured lead concentration in air (PBA) in the workplace. The results obtained were as follows ; 1. The means of blood lead (PBB), blood ZPP and hemoglobin (HB) among workers exposed to lead were $26.1{\pm}8.8{\mu}g/dl,\;28.3{\pm}26.0{\mu}g/dl$ and $16.2{\pm}1.2g/dl$ : whereas those of nonexposed workers were $18.7{\pm}5.1{\mu}g/dl,\;20.6{\pm}8.7{\mu}g/dl$ and $17.3{\pm}1.1g/dl$. The means of above three indicies between two groups showed significant difference statistically (p<0.05). 2. The means of blood lead (PBB), blood ZPP and hemoglobin of workers exposed .to different lead concentration in air were as follows : When it was below $25{\mu}g/m^3$, the indices were $24.7{\pm}79,\;26.1{\pm}26.8{\mu}g/dl\;and\;16.4{\pm}1.1g/dl$ respectively : These indices were $27.1{\pm}8.5,\;23.9{\pm}10.92{\mu}g/dl\;and\;16.2{\pm}1.3g/dl$ when the lead concentration in air was $25{\sim}50{\mu}g/m^3$ : and they were $3.4{\pm}9.3,\;42.3{\pm}31.3{\mu}g/dl\;and\;15.5{\pm}1.2g/dl$ when the concentration of lead was above $50{\mu}g/m^3$. Although there were statistical difference in blood lead and hemoglobin among three different lead concentration in air, there was no statistical difference of blood ZPP among the three groups with different exposure levels (p>0.05). 3. The most frequent by complained symptom was 'Generalized weakness and fatigue', and fewest symptom was 'Intermittent pains in abdomen' 4. Only two symptoms out of fifteen symptoms checked by themselves revealed significant difference between exposed and nonexposed groups. These were 'Intermittent pains of abdomen' and 'Joint pain or arthralgia' (p<0.05), No positive correlation was found between the levels of blood lead and symptom groups categorized as gastrointestinal, neuromuscular and constitutional symptoms, 5. Blood lead (r=0.3995) and ZPP (r=0.2837) showed statistically significant correlation with mean lead concentration in air, whereas correlations were not demonstrated between blood lead and lead related symptoms or blood ZPP and lead related symptoms. 6. Blood lead (PBB) and ZPP showed association (r=0.2466) and the equation PBB=23.75+0.0842 ZPP was derived. 7. On stepwise multiple regression, using blood lead level as a dependent variable and ZPP, hemoglobin (HB), age, work duration (WD) and symptom prevalence as a independent variables, only ZPP significantly contributed a lot to blood lead level. 8. While the ZPP measurement was found to be a good indicator in evaluating health effect of lead absorption in low level lead exposure, lead related symptoms were not sensitive enough to evaluate of lead absorption in low level exposure.

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Several causes of non virus-induced mosaic symptom on potato leaves and its induction by herbicides (감자 이상모자이크증상의 몇 가지 발생원인 및 제초제에 의한 증상 유기)

  • Kwon, Min;Hahm, Young-Il;Kim, Hyun-Jun;Yiem, Myoung-Soon
    • The Korean Journal of Pesticide Science
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    • v.5 no.2
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    • pp.45-50
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    • 2001
  • In recent, non virus-induced mosaic symptoms(NVMS) on potato leaves were observed in the seed potato fields, and its incidence rate was $5{\sim}20%$ nationwide. It made difficult to rogue out virus-infected plants, and caused much arguments between seed potato production farmers and seed potato inspectors. The objectives of these experiments were to find out the causes of NVMS, and also to induce mosaic symptom(phytotoxicity) on potato plants by treatment of several herbicides. No significant correlations were found between incidence rates of NVMS and values from soil analyses; soil pH, soil EC, organic matter content, and contents of inorganic constituents($P_2O_5,\;NO_3$, Ca, Mg, K) in the soil around the potato planted. The examinations by ELISA, virus indicator plants, and TEM showed that NVMS on potato leaves was not caused by the viruses infection. But, the use of herbicides could induced the NVMS on potato leaves. The incidence rates of potato treated with pendimethalin linuron of 400 mL/10 a, pendimethalin of 200 mL/10 a, pendimethalin.oxadiazon of 300 mL/10 a, and control were 61.1%, 47.2%, 19.4%, and 1.4%, respectively. Based on these results, we confirmed that the treatment of pendimethalin alone and in mixture with other herbicides were the reason of NVMS on potato leaves. The yields among test plots were similar except dicamba treated plot, which decreased by about 23% compared to control plot. When their progenies harvested in 1999 were planted in the following season, no symptoms of mosaic were observed.

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The visible injury and physiological responses of three varieties of hot peppers to ozone

  • Kim, Bo-Sun;Yun, Sung-Chul
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 2003.10a
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    • pp.93.1-93
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    • 2003
  • A growth chamber fumigation was conducted to evaluate the ozone (O3) on the physiology of three hot pepper, Capsicum annuum L. cultivars, 'dabotab', 'buchon' and 'pochungchun'. Thirty-day old plants were exposed to O3 of 120 nl 1-1 in the chambers for 8 h d-1 for 3 days. Foliar damage due to O3 was different from the varieties, 'dabotab'was most sensitive to O3, 'pochungchun' was medium, and 'buchon' was resistant. Ozone symptom on the leaves was bifacial necorsis. Photosynthesis and stomatal conductance were decreased due to O3 treatment, but they were not much different from the variety. Decreases of net photosynthesis by O3 were 56%, 40% and 35% on 'dabotab', 'buchon' and 'pochungchun', respectively Decreases of stomatal conductance by O3 were 66%, 63%, and 50% on each varieties. Ozone closed the stomata and decrease net photosynthesis on hot peppers regardless of the variety. Light curves on the three varieties were showing similar patterns that O3 damage on net photosynthesis were started at the low levels of light with or without the visible injury, Assimilation-internal CO2 concentration curves of the three cultivars were not different due to the treatment. It means there was not significant biochemical damage Inside the leaves by O3. In conclusion, ozone closed the stomata and damaged light capturing system of the pepper leaves with or without the visible damage. Although visible damage of the leaves could be a good indicator of O3 resistance, the ecophysiological change by O3 were not proportional to the amout of visible injuries

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Characterization of a Novel Cucumber mosaic virus Isolated from Petunia hybrida

  • Han, Kyung-Sook;Choi, Gug-Seoun;Chung, Bong-Nam;Cho, Jeom-Duk;Cho, In-Sook;Kim, Kee-Hong;Kim, Su;Yoon, Ju-Yeon;Choi, Seung-Kook
    • The Plant Pathology Journal
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    • v.28 no.3
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    • pp.299-305
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    • 2012
  • Petunia hybrida is commonly used in landscapes and interiors for its attractive flower. Virus-like foliar symptoms, including a mosaic with dark green islands surrounding the veins and chlorosis on the leaf margins, were observed on a petunia plant from Icheon, Gyeonggido, Korea. Cucumber mosaic virus (CMV) was identified in the symptomatic petunia by serological testing for the presence of CMV coat protein (CP) with a direct antibody-sandwich-enzyme-linked immunosorbent assay. An agent was mechanically transmitted to indicator plant species including Chenopodium quinoa. Examination of the inoculated plant leaves by RT-PCR analysis and electron microscopy revealed the presence of specifically amplified CP products and spherical virions of approximately 28 nm in diameter, respectively, providing confirmation of a CMV infection. Analysis of CP sequences showed that CMV petunia isolate (CMVYJC) shared 82.5-100% amino acid sequence identity with CPs of representative CMV strains. Phylogenetic analysis of CPs supports that CMV-YJC is a member of CMV subgroup IA (CMV-IA) and has biological properties of CMV-IA on host species. To our knowledge, this is the first report of CMV from P. hybrida in Korea.

Establishment of Quick Model for Private Consumption Symptom (민간소비 이상징후에 대한 속보성 모형 구축)

  • Ahn, Sung-Hee;Lee, Zoonky;Ha, Ji-Eun
    • The Journal of Bigdata
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    • v.2 no.1
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    • pp.59-69
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    • 2017
  • According to precedent research of disaster economics, most of the studies are either based on belated macroeconomic indicators or are limited to specific industries. It is certain that preventing disaster is important, but immediate analysis and reconstruction policy are crucial as well. This research analyzed the ripple effect of consumer spending followed by April 16 ferry disaster and MERS outbreak; it was done by applying credit card company's real-time big data with Marketing Mix Modeling. The main focus of this research is to see if it is possible to predict the scale of damage during ongoing disasters. It is found that setting up weekly MMM and moving the timeline draws significance conclusion. When disasters or events occur in future, this research may be the basis of building quick and intuitive indicator to monitor possible effects.

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Characteristics of Potato Virus Y (PVY) Mutant Isolated from PVY Resistance Breeding Line in Korea (국내 감자바이러스 Y (PVY) 저항성 육성 계통에서 분리한 PVY Mutant의 특성)

  • Kim, Jae-Hyun;Kuem, Wan-Soo;Lee, Sin-Ho;Kim, Jeong-Soo;Jeon, Yong-Ho;Jung, Suk-Hun;Chung, Youl-Young;Park, Yong-Hack
    • Journal of the Korean Society of Tobacco Science
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    • v.28 no.2
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    • pp.100-110
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    • 2006
  • A mutant of Potato vims Y (PVY) was occurred in PVY resistance flue-cured tobacco breeding line KF0402 $(TC1146{\times}KF117)$ showing vein necrosis at Suwon in Korea. This isolate, PVY-SWM, was differentiated from other PVY based on biological properties and nucleotide sequence analyses of coat protein gene. PVY-SWM caused typical symptoms on 21 indicator plants as compared to the PVY-TOJC37. Remarkably, the PVY-SWM induced distinctly different symptom of systemic vein necrosis on tobacco cultivars V.SCR, PBD6, TN86, TN90, Virgin A Mutant (VAM), Wislica, NC744, KB108 and KB111, which were reported to have the recessive potyvirus resistance gene va. In RT-PCR assays with specific primers for detection of PVY, a single band of about 800bp in length was produced. The amplified DNA was cloned and the nucleotide sequence was determined. The coat protein gene of PVY-SWM showed 88.4%-99.0% and 92.5%-98.5% identities to the 12 different PVY isolates of Genbank Database at the nucleotide and amino acidi respectively. Multiple alignments as well as cluster dendrograms of PVY-SWM isolate revealed close phylogenetic relationship to the $PVY^{NTN}$ subgroup.

Is the Neutrophil-Lymphocyte Ratio an Indicator of Progression in Patients with Benign Prostatic Hyperplasia?

  • Tanik, Serhat;Albayrak, Sebahattin;Zengin, Kursad;Borekci, Hasan;Bakirtas, Hasan;Imamoglu, M. Abdurrahim;Gurdal, Mesut
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.15
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    • pp.6375-6379
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    • 2014
  • Purpose: The aim of this study was to evaluate inflammation parameters and assess the utility of the neutrophil-lymphocyte ratio (NLR) as a simple and readily available predictor for clinical disease activity in patients with nenign prostate hyperplasia BPH. We also aimed to investigate the relationship between inflammatory parameters with ${\alpha}$-blocker therapy response, and evaluate the potential association between NLR and the progression of benign prostatic hyperplasia (BPH). Materials and Methods: We examined 320 consecutive patients (July 2013-December 2013) admitted to our outpatient clinic with symptoms of the lower urinary tract at Bozok University. The mean age was 60 (range, 51-75) years. Complete blood count (CBC), prostate-specific antigen (PSA), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were assessed. Correlations between PSA, CRP, ESR, prostate volume, International Prostate Symptom Score (IPPS), maximum urinary flow rate (Qmax), and NLR were assessed statistically. Patients were divided into two groups: high and low risk of progression. Results: NLR was positively correlated with IPSS (p=0.001, r=0.265), PSA (p=0.001, r=0.194), and negatively correlated with Qmax (p<0.001, r=-0.236). High-risk patients a had a higher NLR compared with low-risk patients, based on IPSS (p<0.001), PSA (p=0.013), and Qmax (p<0.001); however, there were no significant differences between the groups in terms of age (p>0.05), and prostate volume (p>0.05). Conclusions: NLR can predict BPH progression. We propose that increased inflammation is negatively associated with clinical status in BPH patients and suggest that NLR can give information along with LUTS severity which may be used as a readikly accessible marker for patient follow-up.

Perceived social support, Instrumental support Needs, and Depression of Elderly women (여성 노인의 사회적지지 및 도구적 지지요구과 우울에 관한 연구)

  • Tak, Young-Ran;Kim, Soon-Ae;Lee, Bong-Suk
    • Women's Health Nursing
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    • v.9 no.4
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    • pp.449-456
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    • 2003
  • Purpose: The purpose of this study was investigate the relationships among perceived social support, instrumental support needs, and depression of healthy, community dwelling elderly women. Method: This study was designed to examine whether the perceived social support and instrumental support were correlated with depression in elderly women. Data were cross-sectional and community-dwelling elderly individuals. The subject was 98 elderly women recruited from Elderly Welfare Center and Community center for Elderly. The instruments for this study were Personal Resource Questionnaire-part II, Geriatric Depression Scale (Short Form), and Instrumental Support Activities Checklist. Data were gathered by means of structured personal interviews. The internal consistency of the instruments was relatively good. Result: The participants' perceived social support was moderately high and instrumental support needs was low. Depression was mild and moderate relatively. The correlation analysis showed that the perceived social support was negatively related to depression and negatively related with instrumental support needs. Conclusion: The findings suggested that more perceived social support, less their depressive symptom in elderly women. It also revealed that the age, marital status, and socioeconomic status of elderly women also are important indicator of the elderly depression. Therefore nursing assessment and the design of intervention that incorporate the determinants supported in this study, such as perceived social support of the elderly women are needed in adopting and maintain health promoting lifestyle for the mental health and effective functioning in later life in women.

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Characterization of an Isolate of Cucumber mosaic virus Isolated from Chinese aster (Callistephus chinensis) (과꽃에서 분리한 Cucumber mosaic virus의 성질)

  • Oh, Sun-Mi;Kim, Sung-Ryul;Hong, Jin-Sung;Ryu, Ki-Hyun;Lee, Gung-Pyo;Choi, Jang-Kyung
    • Research in Plant Disease
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    • v.14 no.3
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    • pp.229-232
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    • 2008
  • An isolate of Cucumber mosaic virus (CMV), designated as Cas-CMV, was isolated from Chinese aster (Callistephus chinensis) showing severe mosaic symptom, and its properties was compared to the well-characterized Fny-CMV (subgroup IA) and As-CMV (subgroup IB) by host reaction in several indicator plants, dsRNA analysis, RT-PCR analysis, and restriction enzyme profile of the PCR products. Cas-CMV differed markedly in their host reaction to Fny-CMV or As-CMV in Cucurbita pepo cv. Black beauty. In the zucchini squash, all strains induced chlorotic spot on inoculated leaves and mosaic symptoms on upper leaves. However, symptoms induced by Cas-CMV were developed lethal necrosis on the young plants 15 to 20 days after inoculation. In experiments of dsRNA analysis and RT-PCR analysis, properties of Cas-CMV was come within subgroup I CMV. Moreover, restriction enzyme analysis using HindIII of the RT-PCR products showed that Cas-CMV belong to a member of CMV subgroup IA.

The Study on Common Cold recorded in Chinese Medical Journal (중의잡지(中醫雜誌)에 보고(報告)된 감모(感冒)에 대(對)한 고찰(考察))

  • Lim, Do-Hee;Bae, Han-Ho;Park, Yang-Chun
    • Journal of Haehwa Medicine
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    • v.13 no.2
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    • pp.231-249
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    • 2004
  • This study analyzed the contents of the research papers concerning the common cold recorded in Chinese medical journal published over the period between 2000 and 2004. As a result, the following conclusion was drawn. 1. Among the clinical research papers, There are a lot of treatment papers of traditional chinese medicine in the method of treatment. There are a lot of papers about Feng-Re-Xing(風熱型) and Xu-Zheng-Xing(虛證型) in the Bian-Zheng-Lei-Xing(辨證類型) 2. "Zhong-Yi-Xu-Zheng-Bian-Zheng-Can-Kao-Biao-Zhun" ("中醫虛證辨證參考標準"), "Zhong-Yi-Nei-Ke-Wu-Ban-Jiao-Cai"("中醫內科五版敎材"), "Zhong-Hua-Ren-Min-Gong-He-Guo-Zhong-Yi-Yao-Hang-Ye-Biao-Zhun"("中華人民共和國醫藥行業標準"), "Gan-Mao-Zhen-Duan-Biao-Zhun"("感冒診斷漂準"), "Zhong-Yi-Bing-Zheng-Zhen-Duan-Liao-Xiao-Biao-Zhun"("中醫病證診斷療效標準"), "Quan-Guo-Gao-Deng-Yi-Xue-Yuan-Xiao-Zhong-Yi-Zhuan-Ye-Jiao-Cai"("全國高等醫藥院校中醫專業敎材") are used as the criterion for diagnosis in Chinese medicine. 3. It is mainly used "Zhong-Yi-Bing-Zheng-Zhen-Duan-Liao-Xiao-Biao-Zhun"("中醫病證診斷療效標準") as the criterion for treatment effect evaluation, and symptom of traditional chinese medicine, the frequency and the duration of common cold, measurement of immunologic function are used as assistant evaluation indicator. 4. The research papers reported that the use of prescriptions such as Chai-Qi-Fang-Jiao-Tang, Tui-Re-He-Ji(退熱合劑), Ti-Xu-Gan-Mao-He-Ji(體虛感冒合劑), Yu-Ping-Feng-San-He-Gui-Zhi-Tang(玉屛風散合桂枝湯), Chai-Guan-Jie-Re-Ke-Li(柴貫解熱顆粒), Hu-Qin-He-Ji(蒿芩合劑), Lian-Hua-Feng-Cha(蓮花峰茶), Kang-Gan-He-Ji(抗感合劑), Bing-Du-He-Ji(病毒合劑), Zhong-Gan-Ling-Pian(重感靈片) led to the high efficacy 5. The pharmacological research papers reported that Yu-Ping-Feng-San(玉屛風散) have influence on IgA, phagocytic function of macrophage, the total number of splenocyte and PEC.

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