• Molecules and Cells
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• v.42 no.3
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• pp.218-227
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• 2019

This study was designed to determine the effects of the long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) on vascular smooth muscle cell (VSMC) apoptosis and extracellular matrix (ECM) disruption in a murine abdominal aortic aneurysm (AAA) model. After injection of PVT1-silencing lentiviruses, AAA was induced in Apolipoprotein E-deficient ($ApoE^{-/-}$) male mice by angiotensin II (Ang II) infusion for four weeks. After Ang II infusion, mouse serum levels of pro-inflammatory cytokines were analysed, and aortic tissues were isolated for histological, RNA, and protein analysis. Our results also showed that PVT1 expression was significantly upregulated in abdominal aortic tissues from AAA patients compared with that in controls. Additionally, Ang II treatment significantly increased PVT1 expression, both in cultured mouse VSMCs and in AAA murine abdominal aortic tissues. Of note, the effects of Ang II in facilitating cell apoptosis, increasing matrix metalloproteinase (MMP)-2 and MMP-9, reducing tissue inhibitor of MMP (TIMP)-1, and promoting switching from the contractile to synthetic phenotype in cultured VSMCs were enhanced by overexpression of PVT1 but attenuated by knockdown of PVT1. Furthermore, knockdown of PVT1 reversed Ang II-induced AAA-associated alterations in mice, as evidenced by attenuation of aortic diameter dilation, marked adventitial thickening, loss of elastin in the aorta, enhanced aortic cell apoptosis, elevated MMP-2 and MMP-9, reduced TIMP-1, and increased pro-inflammatory cytokines. In conclusion, our findings demonstrate that knockdown of lncRNA PVT1 suppresses VSMC apoptosis, ECM disruption, and serum pro-inflammatory cytokines in a murine Ang II-induced AAA model.

• The Journal of Korean Institute of Information Technology
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• v.16 no.11
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• pp.23-34
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• 2018

This paper presents the high efficiency and high power-factor power supply for LED lighting equipment. The proposed power supply is the single-stage power structure consisted of the full-bridge diode rectifier and flyback converter, and thus the power-factor correction and output voltage regulation are performed simultaneously using only one controller IC and one power semiconductor switch. Furthermore, the proposed power supply reduces the voltage stress and switching loss of main switch using the regenerative snubber, and it improves the system efficiency using the synchronous rectifier. The applied synchronous rectifier is the new voltage-driven type and its operation and construction are simple. In this paper, the operation principle of proposed power supply is explained through the operation analyses of its power-factor correction and main power conversion parts and the operation of synchronous rectifier is described, briefly. Also, a design example of the power circuit of 40W-class prototype is shown and the operation characteristics of proposed power supply are validated through the experimental results of the implemented prototype by the designed circuit parameter.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.21 no.2
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• pp.143-149
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• 2021

BLDC motors are getting better performance due to the improvement of material technology including high performance of permanent magnets, advancement of driving IC technology with high integration and high functionality, and improvement of assembly technology such as high point ratio. While having the advantage of such a square wave driven BLDC motor, interest in the design and development of a square wave driven BLDC permanent magnet motor and development of a position detection circuit and driver is increasing in order to more meet the needs of users. However, in spite of the cost and functional advantages due to reduced efficiency, switching loss and vibration, noise, etc., the application is somewhat limited. Therefore, in this paper, we study a position detection circuit that generates a sinusoidal signal in proportion to the magnetic flux of a BLDC motor rotor using a Hall Effect Sensor that generates a sinusoidal wave to increase the efficiency of the motor, reduce ripple, and drive a sinusoidal current with excellent speed and torque characteristics.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.21 no.4
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• pp.135-141
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• 2021

Interest is growing in the design and development of square wave driven BLDC permanent magnet motors suitable for industrial automation, and the development of position detection circuits and drivers. However, this motor is somewhat limited in its application despite the price and functional advantages due to the decrease in efficiency due to switching loss and vibration and noise. In the process of designing and assembling a BLDC motor, the magnetic pole angle is not uniform or the magnetic flux distribution is distorted due to problems in magnetic circuit design or product non-uniformity in the assembly process. Therefore, these things cause position detection deviation and deteriorate the motor characteristics. In addition, the sine wave driven BLDC system can operate stably only when the signal generated from the position sensor is accurately fed back to the driver. However, since the generated signal cannot perform stable position detection due to the occurrence of DC offset component due to magnetic flux density deviation or magnetization technology, which is an external influence, this study intends to study the proposed circuit that can remove the DC offset component.

• Journal of Powder Materials
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• v.29 no.4
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• pp.283-290
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• 2022

A Cu-15Ag-5P filler metal (BCuP-5) is fabricated on a Ag substrate using a high-velocity oxygen fuel (HVOF) thermal spray process, followed by post-heat treatment (300℃ for 1 h and 400℃ for 1 h) of the HVOF coating layers to control its microstructure and mechanical properties. Additionally, the microstructure and mechanical properties are evaluated according to the post-heat treatment conditions. The porosity of the heat-treated coating layers are significantly reduced to less than half those of the as-sprayed coating layer, and the pore shape changes to a spherical shape. The constituent phases of the coating layers are Cu, Ag, and Cu-Ag-Cu3P eutectic, which is identical to the initial powder feedstock. A more uniform microstructure is obtained as the heat-treatment temperature increases. The hardness of the coating layer is 154.6 Hv (as-sprayed), 161.2 Hv (300℃ for 1 h), and 167.0 Hv (400℃ for 1 h), which increases with increasing heat-treatment temperature, and is 2.35 times higher than that of the conventional cast alloy. As a result of the pull-out test, loss or separation of the coating layer rarely occurs in the heat-treated coating layer.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.37 no.1
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• pp.101-105
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• 2024

4H-SiC power metal-oxide-semiconductor field effect transistors (MOSFETs) have been developed to achieve lower specific-on-resistance (R_on,sp), and the gate oxides have been thermally grown. The poor channel mobility resulting from the high interface trap density (D_it) at the SiO₂/4H-SiC interface significantly affects the higher switching loss of the power device. Therefore, the development of novel fabrication processes to enhance the quality of the SiO₂/4H-SiC interface is required. In this paper, NO post-oxidation annealing (POA) by using the conditions of N₂ diluted NO at a high temperature (1,300℃) is proposed to reduce the high interface trap density resulting from thermal oxidation. The NO POA is carried out in various NO ambient (0, 10, 50, and 100% NO mixed with 100, 90, 50, and 0% of high purity N₂ gas to achieve the optimized condition while maintaining a high temperature (1,300℃). To confirm the optimized condition of the NO POA, measuring capacitance-voltage (C-V) and current-voltage (I-V), and time-of-flight secondary-ion mass spectrometry (ToF-SIMS) are employed. It is confirmed that the POA condition of 50% NO at 1,300℃ facilitates the equilibrium state of both the oxidation and nitridation at the SiO₂/4H-SiC interface, thereby reducing the D_it.

• The Journal of the Korea institute of electronic communication sciences
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• v.18 no.6
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• pp.1081-1086
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• 2023

The rapid growth and increasing complexity of modern networks have highlighted the limitations of traditional network architectures. The emergence of SDN (Software-Defined Network) in response to these challenges has changed the existing network environment. The SDN separates the control unit and the data unit, and adjusts the network operation using a centralized controller. However, this structure has also recently caused a huge amount of traffic due to the rapid spread of numerous Internet of Things (IoT) devices, which has not only slowed the transmission speed of the network but also made it difficult to ensure quality of service (QoS). Therefore, this paper proposes a method of load distribution by switching the IP and any server (processor) from the existing data processing scheduling technique, RR (Round-Robin), to mapping when a large amount of data flows in from a specific IP, that is, server overload and data loss.

• Journal of the Korean Society for Railway
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• v.19 no.6
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• pp.727-735
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• 2016

Smart transformers are effective at reducing the weight and increasing the efficiency of traction systems for railroad applications. A smart transformer generally consists of rectifier modules and the Dual-Active-Bridge (DAB) converter modules. The efficiency of the smart transformer depends on not only the electrical characteristics, but also on the control method of the converter modules. Especially, a DAB converter has a high order degree of freedom of voltage modulation to control the power transferred through the high frequency transformer, and a voltage modulation method, are very critical for the efficiency of the DAB converter. This paper proposes a new voltage modulation method for the DAB converter to increase the efficiency in the low/medium power transfer condition. The proposed modulation method controls the reactive power in the high frequency transformer, making it zero. And, the switching loss is dramatically reduced by using the received converter module as a diode rectifier. The feasibility of the proposed modulation method is verified by computer simulation of the 900Vdc DAB converter power control.

• Journal of Periodontal and Implant Science
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• v.47 no.5
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• pp.312-327
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• 2017

Purpose: This study assessed marginal bone remodeling and soft tissue esthetics after the loading of single bone-level implants in the anterior maxilla. Methods: An open, single-arm observational clinical trial with 3 years of follow-up was performed, including 22 implants. The patients presented with a single tooth gap in the anterior maxilla (tooth positions 14-24), with natural or restored adjacent teeth. An implant was placed at least 8 weeks post-extraction and healed submerged for 6 weeks. After the second-stage operation, a fixed provisional prosthesis was provided. The final restoration was placed 6 months after the provisional restoration. The time of the provisional crown connection was considered to be the baseline in this study. Esthetic parameters and the marginal bone level were assessed at 6, 12, 24, and 36 months. Results: All implants were well integrated in the bone. A statistically significant increase was found in the mean implant stability quotient between the time of the provisional prosthesis and the time of the final prosthesis. Most implants (95.5%) revealed marginal bone resorption (<0.5 mm), and just 1 implant (4.5%) showed a change of 2.12 mm from baseline to 36 months (mean $0.07{\pm}0.48mm$), while the crestal bone level decreased significantly, from $2.34{\pm}0.93mm$ at baseline to $1.70{\pm}1.10mm$ at 36 months. The facial gingival margin and papilla were stable and the esthetic scores indicated high patient and dentist satisfaction. Conclusions: Platform-switching bone-level implants placed in maxillary single-tooth gaps resulted in successful osseointegration with minimal marginal bone resorption. The peri-implant soft tissue was also esthetically satisfying and stable.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.10
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• pp.34-40
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• 2014

With the economical data service delivery, the packet transport network (PTN) technologies have emerged as an important player in the next-generation transport networks. As the PTN continues to make such considerable progress, it is being challenged by network providers who need rapid and reliable recovery capabilities to guarantee the availability of their services. This paper introduces several fault detection mechanisms for a client signal failure in packet transport networks and proposes a reliable transmission method of IP flows from routers using the combination of Ethernet services. Based on the first fault detection methods, client signal fault is detected within tens or hundreds of milliseconds. It enables the client network devices to perform their own recovery processes within one second. The second mechanism enables failed Ethernet services to be bypassed via other Ethernet services over disjoint paths, so as to contribute on reducing packet loss of IP traffic.