• 한국임상수의학회지
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• 제13권2호
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• pp.184-194
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• 1996

A comparative study of three absorbable suture materials of chromic catgut, Dexon II (a polyglycolic acid suture with a polycaprolate coating system) and Coated Vicryl (a polyglactin 910 suture with a glycolide-lactide-calcium stearate coating system) was undertaken in terms of tensile strength, breaking elongation, appearances of the suture materials in the subcutaneous layer of rats and of tissue reaction in the intramuscular layer of rats. The initial tensile strength of chromic catgut and the tensile strength after 21 days were about 1.55 kg and 0.19 kg, respectively. Those of Dexon II were about 2.01 kg and 0. 20 kg, respectively. Those of Coated Vicryl were about 2.39 kg and 0.48 kg, respectively. Coated Vicryl showed the highest tensile strength among the three materials during the whole period. On the other hand, Dexon II showed the highest breaking elongation among the three materials during the first week. But the breaking elongation of Dexon II rapidly continuously decreased during the whole period. The appearances of the suture materials in the subcutaneous layer of rats showed that chromic catgut was the fastest among the three materials, whereas it formed comparatively much connective tissue. The intramuscular absorption rate and tissue reaction of Dexon II were similar to those of Coated Vicryl. The intramuscular absorption rate of these was fairly late when compared with chromic catgut. And the tissue reaction appearance of these showed the formation of a granuloma with foreign body giant cells, macrothages and epitheloid cells by the 28th day in the experimental period.

• 대한기관식도과학회지
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• 제7권1호
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• pp.9-13
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• 2001

Background： Tracheal resection and end-to-end anastomosis are the preferred treatment for tracheal tumor or tracheal stenosis. Absorbable suture material has been commonly used in case of tracheal anastomosis. But anastomosis technique is controversial. This experimental study compared between interrupted suture and continuous suture using Polydioxanone (PDS) absorbable suture material after tracheal resection and end-to-end anastomosis in rabbits. Methods : Twenty-four rabbits were used, divided into two groups of 12 animals each. The trachea was resected and then anastomosed with continuous 6-0 polydioxanone (PDS) (group 1), and intermittent 6-0 polydioxanone (PDS) (group 2). The animals were followed up for 6 months. Stenosis of the trachea was assessed at the time of death. Results : In two groups, anteroposterior diameter, transverse diameter, cross sectional area, and perimeter were greater in group 2 than in group 1 but, not significantly different. In addition, histologic findings were not different in two groups. Conclusions : This study suggest that stenosis after tracheal resection and end-to-end anastomosis using absorbable polydioxanone (PDS) suture material be not significantly different in both groups.

• 한국임상수의학회지
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• 제40권6호
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• pp.423-428
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• 2023

The mouse kidney transplantation model serves as an invaluable tool for exploring various aspects of the transplant process, including acute rejection, cellular and humoral rejection, ischemia-reperfusion injury, and the evaluation of novel therapeutic strategies. However, conducting venous anastomosis in this model poses a significant challenge due to the thin and pliable characteristics of the renal vein, which often obstruct clear visualization of the resected vein's edge. This study proposes the adoption of a two stay suture technique to enhance the visualization of the renal vein's edge, thereby facilitating efficient and successful venous anastomosis. A total of 22 mice served as kidney donors in this study. The conventional anchoring suture technique was employed for venous anastomosis in 11 of these mice, while the remaining 11 underwent the two stay suture technique. The anastomosis duration and completion rates were then compared between these two groups. The conventional anchoring suture technique yielded an average anastomosis time of 29 minutes and a completion rate of 64%. In contrast, the two stay suture technique demonstrated a substantial improvement, with an average anastomosis time of 14 minutes and a completion rate of 100%. The two stay suture technique offers a promising solution to enhance visualization during venous anastomosis in murine kidney transplantation. This technique may particularly benefit novices by enabling them to perform venous anastomosis more easily, swiftly, and successfully.

• 대한정형외과스포츠의학회지
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• 제10권2호
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• pp.69-77
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• 2011

목적: 만성 발목관절 외측 불안정성 환자에 대한 변형 Brostrom 술식에서 단일 봉합나사와 이중 봉합나사를 이용한 기법간의 임상 결과를 후향적으로 비교하고자 하였다. 대상 및 방법: 본원에서 봉합나사를 이용한 변형 Brostrom 술식을 시행받은 환자들 중 최소 1년 이상 추시가 가능하였던 37례를 대상으로 하였다. 모든 수술은 동일한 술자에 의해 이루어졌으며 단일 봉합나사를 이용한 경우가 17예, 이중 봉합나사를 이용한 경우가 20예 였다. 임상적 결과의 평가는 Karlsson 점수 및 Sefton의 평가법을 이용하였고, 발목관절의 기계적인 안정성에 대한 방사선학적 평가로 Telos 기기를 이용한 전방 전위 및 내반 스트레스 검사가 이용되었다. 결과: Karlsson 점수는 단일 봉합나사군이 술 전 평균 45.2점에서 술 후 89.4점으로, 이중 봉합나사군이 술 전 평균 46.4점에서 90.5점으로 각각 호전되었다. Sefton 평가법상 단일 봉합나사군은 우수가 7예, 양호가 8예, 보통이 2예 였고, 이중 봉합나사군은 우수 8예, 양호 10예, 보통 2예로 나타나 각각 15례(88.2%), 18례(90%)에서 만족스러운 결과를 보였다. 스트레스 방사선검사 상 거골 경사각과 거골 전방전위는 단일 봉합나사군이 술 전 평균 13.6도, 8.6 mm에서 술 후 최종 추시시 5.4도, 4.1 mm로, 이중 봉합나사군이 술 전 평균 14.1도, 8.4 mm에서 술 후 3.9도, 4 mm로 각각 호전되었으며 두 기법간에 술 후 거골 경사각의 유의한 차이를 보였다(p<0.05). 결론: 만성 발목관절 외측 불안정성에 대한 변형 Brostrom 술식에서 단일 봉합나사와 이중 봉합나사를 이용한 기법간에 술 후 임상 결과의 유의한 차이는 없었으나, 발목관절의 기계적인 안정성은 이중 봉합나사군에서 더 우수하였다. 단일 봉합나사와 이중 봉합나사를 이용한 변형 Brostrom 술식 모두 효과적인 치료 방법이라고 생각되며, 향후 운동 선수들을 대상으로 한 치료결과 및 생역학적 분석이 필요할 것으로 생각한다.

• 대한관절경학회지
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• 제13권3호
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• pp.280-284
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• 2009

목적: 버팀테응력 회복을 위한 아탈구 된 내측 반월상 연골의 봉합나사(suture anchor)를 이용한 관절경적 정복술을 보고하고자 한다. 수술 수기: 전외측, 전내측, 중슬개골 도달법을 기본으로 사용하였다. 전외측 도달법으로 관절경을 삽입하여 내측 반월상 연골판의 아탈구를 먼저 확인 하였으며, 내측 반월상 연골판의 방사선 파열이 있는 경우에는 이번 연구에서 제외 하였다. 전내측 삽입구를 통하여 내측 반월상 연골판의 전방부를 유리 시킨 후, 봉합 나사가 삽입 될 곳의 피질골을 전동식 연마기를 이용하여 제거하였다. 중슬개골 도달법을 이용하여 봉합 나사(suture anchor)를 삽입 하였으며, 90도의 봉합 갈고리와 2.0 Nylon을 이용하여 봉합 나사의 봉합사를 연골판에 통과 시킨 후, Sliding knot-tying technique을 사용하여 연골판을 고정시켰다. 환자들은 술 후 6주간 체중 부하를 금지 하였다. 결론: 내측 반월상 연골의 아탈구에 있어 최소한의 손상으로 버팀테응력 회복을 통하여 슬관절의 안정성을 증진시킬 수 있는 술식으로 봉합 나사(Suture Anchor)를 이용한 관절경적 정복술을 소개한다.

• 대한관절경학회지
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• 제17권1호
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• pp.95-99
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• 2013

견관절 전방 불안정성을 야기하는 전하방 관절낭-관절와순 복합체 손상에 대해 antegrade suture passer를 이용하여 효과적으로 복원할 수 있는 관절경적 봉합술을 소개하고자 한다. 후방 삽입구를 통해 관절내 병변의 유무를 확인하고, 전상방 및 전하방 삽입구를 만든 뒤 방카트르 병변(Bankart lesion)의 확인 및 봉합 전 처치를 시행한다. 전하방 삽입구를 통하여 첫 번째 봉합 나사를 4시 반 방향에 고정한 다음 한가닥의 봉합사를 Scorpion$^{TM}$을 이용하여 5시 반 방향(우측 견관절 기준)에 있는 관절와와 분리 및 퇴축된 전하방 관절와-상완인대와 관절낭-관절와순 복합체를 약 10-15 mm 내측에서 통과시킨다. Scorpion$^{TM}$의 고리를 이용하여 통과시킨 봉합사를 삽입구로 빼낸 다음 SMC 매듭을 이용하여 봉합한다. 이후 3시 반, 2시 반 방향의 관절와에 각각 봉합 나사를 삽입하고 기존의 방법인 봉합 갈고리와 shuttle-relay technique을 이용하여 관절와순 봉합을 완성한다. 본 술기는 기존의 봉합 갈고리를 이용한 봉합술로는 어려웠던 5시 내지 5시 반 방향의 전하방 관절와-상완인대에 대한 해부학적 복원을 쉽게 얻을 수 있으며, 특히 초보자나 경험이 적은 술자에게 유용한 술식으로 사료된다.

• 대한소아치과학회지
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• 제48권1호
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• pp.31-41
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• 2021

연구의 목적은 7세부터 15세 사이 소아청소년을 대상으로 정중구개봉합의 성숙도와 SMI 및 MP3 방법으로 평가된 골 성숙도와의 연관성을 분석하고 수완부 골 성숙도와 중지의 중절골 성숙도가 정중구개봉합 성숙 단계를 예측할 수 있는 지표로 사용될 수 있는지 알아보기 위함이다. 이번 연구 대상은 무작위로 선택된 7세부터 15세 사이 남자 132명과 여자 135명으로 교정 치료 전 교정 진단을 위해 촬영 되었던 CBCT 수평면 영상 이용하여 정중구개봉합의 성숙도를 5단계로 평가하였고 수완부 방사선 사진을 이용하여 골 성숙도를 평가하였다. 정중구개봉합 성숙도와 SMI 방법으로 평가된 골 성숙도는0.905, MP3 방법으로 평가된 골 성숙도는 0.830으로 강한 상관관계를 보였다. 정중구개봉합 성숙도와 연령의 상관관계는 0.868으로 나타나 비교적 높은 상관관계를 보였다. 이번 후향적 연구를 통해 골 성숙도 평가를 위한 SMI와 MP3 방법은 정중구개봉합 성숙도를 예측할 수 있는 지표로 사용될 수 있음이 증명 되었으며 SMI 방법이 MP3 방법보다 더 나은 신뢰성을 보였다. 따라서 정중구개봉합 성숙도 평가가 필요한 모든 소아환자들을 대상으로 CBCT촬영하는 것은 불필요할 수 있으며 CBCT와 대체 가능한 SMI 와 MP3 방법은 최소의 방사선 피폭으로 간단하게 성장기 아동의 악정형 장치의 최적의 치료 시기 결정의 참고자료로 활용될 수 있을 것이다.

• Archives of Plastic Surgery
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• 제32권2호
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• pp.231-236
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• 2005

Nowadays breast reconstruction with autologous tissues after radical mastectomy is commonly performed, and a natural inframammary fold in the reconstructed breast is considered to be an essential aspect of symmetrical breast shape and location. Total of 104 patients underwent breast reconstruction with free TRAM flap and formation of inframammary fold with free TRAM breast reconstruction was done in 79 patients. No suture fixation for inframammary fold were done in 19 patients. 27 patients(24.0%) were made of inframammary fold with absorbable suture, 52 patients (50.0%) underwent inframammary fold creation with nonabsorbable suture. There were 4 cases(16.0%) of displacement of reconstructed breast and 2 cases(8.0%) of partial disruption of inframammary fold in the group of no suture. There were 2 cases(7.4%) of displacement of reconstructed breast and 3 cases(11.1%) of partial disruption of inframmamary fold in the fixed group with absorbable suture. There was only 1 case(1.9%) of partial disruption of inframammary fold fixed with nonabsorbable suture group. Therefore, we could speculate that the reinforcement of ligamentous structure for making the definite inframammary fold is necessary, and the area of the inframammary fold should not be undermined in immediate breast reconstruction as much as possible in order to preserve the zone of adherence. If the fold is disrupted during the mastectomy, it should be re-created with the non-absorbable sutures. Nonabsorbable suture fixation seemed to be more stable than absorbable suture. Preoperative marking and design are very important to make the symmetrical shape and location of inframammary fold in both of immediate and delayed reconstruction of breasts.

• 대한치과교정학회지
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• 제50권1호
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• pp.42-51
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• 2020

Objective: The objective of this study was to evaluate the effects of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion. Methods: Sixty male Sprague-Dawley rats were divided into 4 groups; the phosphate-buffered saline (PBS)-injected no expansion group, cetirizine-injected no expansion group, PBS-injected expansion group, and cetirizine-injected expansion group, and were observed at 7, 14, and 28 days. Five rats per group were examined at each observation day. Daily injections of cetirizine or PBS were administered to the relevant groups starting 2 weeks prior to expander insertion. A rapid expander was inserted in the calvarial bone to deliver 100 cN of force to the parietal suture. The specimens were prepared for hematoxylin and eosin and tartrate-resistant acid phosphatase (TRAP) staining. Suture opening and bone regeneration were evaluated using microcomputed tomography and bone histomorphometric analysis. Serum blood levels of osteocalcin and carboxy-terminal collagen crosslinks (CTX) were also evaluated. Results: TRAP-positive cell counts and CTX levels decreased while osteocalcin levels increased in the cetirizine-injected expansion group at observation day 28. In the expansion groups, the mineralized area gradually increased throughout the observation period. At day 28, the cetirizine-injected expansion group showed greater bone volume density, greater mineralized area, and narrower average suture width than did the PBS-injected expansion group. Conclusions: Cetirizine injection facilitated bone formation after suture expansion, mostly by suppressing osteoclastic activity. Histamine 1 receptor antagonists may aid in bone formation after calvarial suture expansion in the rat model.

• 대한치과교정학회지
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• 제49권6호
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• pp.360-371
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• 2019

Objective: We sought to determine the predictors of midpalatal suture expansion by miniscrew-assisted rapid palatal expansion (MARPE) in young adults. Methods: The following variables were selected as possible predictors: chronological age, palate length and depth, midpalatal suture maturation (MPSM) stage, midpalatal suture density (MPSD) ratio, the sella-nasion (SN)-mandibular plane (MP) angle as an indicator of the vertical skeletal pattern, and the point A-nasion-point B (ANB) angle for anteroposterior skeletal classification. For 31 patients (mean age, 22.52 years) who underwent MARPE treatment, palate length and depth, MPSM stage and MPSD ratio from the initial cone-beam computed tomography images, and the SN-MP angle and ANB angle from lateral cephalograms were assessed. The midpalatal suture opening ratio was calculated from the midpalatal suture opening width measured in periapical radiographs and the MARPE screw expansion. Statistical analyses of correlations were performed for the entire patient group of 31 subjects and subgroups categorized by sex, vertical skeletal pattern, and anteroposterior skeletal classification. Results: In the entire patient group, the midpalatal suture opening ratio showed statistically significant negative correlations with age, palate length, and MPSM stage (r = -0.506, -0.494, and -0.746, respectively, all p < 0.01). In subgroup analyses, a strong negative correlation was observed with the palate depth in the skeletal Class II subgroup (r = -0.900, p < 0.05). Conclusions: The findings of this study indicated that age, palate length, and MPSM stage can be predictors of midpalatal suture expansion by MARPE in young adults.