• 한국지반공학회논문집
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• 제24권1호
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• pp.71-80
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• 2008

본 논문에서는 보강토 구조물에 보강재로 적용되는 지오그리드의 시간 의존적 변형거동 특성에 대한 광폭 인장시험 결과를 제시하였다. 먼저, 다양한 보강재의 종류에 대해 인장속도에 따른 파단강도 및 강성의 변화에 대해 알아보았다. 또한 보강토 구조물이 사용연한 동안 받게될 다양한 하중 조건, 즉 지속하중 및 반복하중을 작용시킬 수 있는 장비를 특수 제작하여 지오그리드의 시간의존적 변형거동을 분석하였다. 그 결과 지속하중 및 반복하중 작용시 잔류변형은 보강재의 점성(viscous) 특성의 형태로서 쌍곡선 특성 곡선으로 잘 모사되는 것으로 분석되었으며 이러한 잔류변형은 시간의존적 점성거동의 측면에서 다루어야 하는 것으로 나타났다.

• 한국지반공학회논문집
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• 제23권6호
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• pp.5-21
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• 2007

보강토 옹벽은 기존 콘크리트 옹벽에 비하여 많은 장점을 지니고 있으나 장기적으로 지속하중 혹은 반복하중 등에 의한 잔류변형의 우려로 영구 구조물로서의 적극적인 적용에 장애가 되고 있다. 이 문제를 해결하기 위해서는 보강토 구조물의 시간 의존적 잔류변형 메카니즘의 규명과 아울러 잔류변형을 예측하고 제어하는 기술이 확보되어야 한다. 본 연구에서는 이러한 연구의 필요성에 근거하여 보강토 옹벽에 발생할 수 있는 장기변형 특성 고찰에 주안점을 두고 지오그리드와 표준사로 뒤채움된 모형 보강토 옹벽에 대한 지속하중 혹은 반복하중 등 다양한 하중이력에 대한 보강토 구조물의 장기변형 특성 메카니즘을 축소모형실험을 통해 고찰하였다. 그 결과 보강토 옹벽의 시간의존적 변형은 작용하는 하중특성 뿐만 아니라 뒤채움흙 및 보강재의 역학적 특성에도 많은 영향을 받는 것으로 나타났으며, 선행하중을 작용함으로써 시간 의존적 잔류변형을 제어할 수 있는 것으로 파악되었다.

• 한국지반신소재학회논문집
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• 제10권4호
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• pp.105-112
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• 2011

본 논문에서는 지속하중이 작용하는 보강토 구조물의 시간의존적 장기거동에 관한 수치 모델링 기법을 다루었다. 먼저 Power Law 기반의 크리프 모델을 이용하여 지오그리드와 뒤채움흙의 크리프 거동의 모델링에 대한 적용성을 검토 하였으며 나아가 보강토 교대 구조물의 장기 거동에 대한 해석에 적용하였다. 그 결과 Power Law 기반의 크리프 모델은 지오그리드와 뒤채움흙으로 구성되는 보강토 교대 구조물에 지속하중 작용시 발생하는 크리프 변형을 적절히 모사할 수 있는 것으로 검토되었으며 크리프 변형이 발생할 수 있는 뒤채움흙을 사용하는 경우 교대 벽체 및 상판기초에 허용치를 초과하는 변위가 발생할 수 있는 것으로 검토되었다. 본 연구에서 얻어진 결과의 실무적 적용 방안에 대한 내용을 기술하였다.

• Journal of Pharmaceutical Investigation
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• 제29권4호
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• pp.309-313
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• 1999

This study was prepared to develop the sustained release dosage form of phenylpropanolamine hydrochloride (PPA) by complexation with cation exchange resin(CER). The PPA-CER complex was confirmed by differential scanning calorimetry(DSC) thennogram, indicating a relative shift of an endometric peak of PPA to higher temperature. The loading efficiency was increased as the amount of PPA was increased as well as the time of fractional exchange was advanced as the temperatures were increased. Loading efficiency, fractional exchange, reaction rate constant and activation energy were highly dependent on the temperature and drug : resin ratio. The optimal ratio of PPA and resin was estimated to be 10: 10 for the sustained release.

• Steel and Composite Structures
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• 제35권1호
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• pp.93-109
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• 2020

Developed from conventional concrete filled steel tubular (CFST) members, concrete-encased CFST has attracted growing attention in building and bridge practices. In actual construction, the inner CFST is erected prior to the casting of the outer reinforced concrete part to support the construction preload, after which the whole composite member is under sustained service load. The complex loading sequence leads to highly nonlinear material interaction and consequently complicated structural performance. This paper studies the full-range behaviour of concrete-encased CFST columns with initial preload on inner CFST followed by sustained service load over the whole composite section. Validated against the reported data obtained from specifically designed tests, a finite element analysis model is developed to investigate the detailed structural behaviour in terms of ultimate strength, load distribution, material interaction and strain development. Parametric analysis is then carried out to evaluate the impact of significant factors on the structural behaviour of the composite columns. Finally, a simplified design method for estimating the sectional capacity of concrete-encased CFST is proposed, with the combined influences of construction preload and sustained service load being taken into account. The feasibility of the developed method is validated against both the test data and the simulation results.

• 펄프종이기술
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• 제32권1호
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• pp.1-9
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• 2000

This study was carried out to improve the opacity of printing paper. Conventional filler loading enhanced the opacity of paper, but subsequently caused reduction of paper strength of paper. We try to seek a new filler loading method so-called beater loading that enhances opacity of paper as well as sustained desire strength. In our experiment, comparing to direct loading method, the beater loading method enhanced 0.8% of opacity and 0.2% of brightness. This also decreased the rates of strength reduction of paper. Therefore, the results obtained in this study indicated that beater loading was a very effective method to improve the opacity of paper while not to decreased so much of paper strength.

• 대한의용생체공학회:의공학회지
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• 제16권3호
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• pp.367-375
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• 1995

광범위 항생물질인 Ampicillin sodium(AMP-Na)을 두가지 방법 즉, 단순섞임과 bovine serum albumin(BSA)으로 microsphere화한 후 loading 하는 방법으로 fibrin glue(FG)를 제조하였고 이 FG로부터 AMP-Na의 서방성 시험을 시도하였다. 단순섞임의 경우 fibrinogen(FBNG)의 농도를 조적함으로서 FG로부터 AMP-Na의 지속적 방출을 달성할 수 있었으며 특히 이 microsphere를 glutaraldehyde로 가교화시킴으로서 용출속도를 더욱 늦출 수 있었다.(tO.9 : 33hr). FG의 rat perironeum에 대한 접착력은 FBNG과 thrombin의 농도가 각각 5.0%, 25~50 NIHU/ml에서 최대로 나타났다. Factor XIII의 농도는 0~500 U/1g of FBNG의 범위내에서 접착력에 거의 영향을 미치지 않았으며 incubation time은 60분일 때 최대로 나타났다. FG에 AMP-Na 및 BSA micorsphere를 loading하여도 접착력에는 큰 영향을 미치지 않았다.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1999년도 학회창립 10주년 기념 1999년도 가을 학술발표회 논문집
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• pp.779-782
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• 1999

This study was carried out to estimate the effects of the loading conditions on the corrosion of reinforcing bars and permeation of chloride ion. The permeation of chlorides depends not only on the transfer properties in concrete but also on the load applied in the case of reinforced concrete structures. Recent studies reported that the loading conditions affected the corrosion rate of the reinforcing bars under existence of an external current supply. But it was not reported that loading conditions affected corrosion of reinforcing bar caused by the characteristics of permeation and the process of cracking. In this experiment, it was shown that the corrosion of reinforcing bars and the characteristics of permeating were greatly affected by the loading conditions.

• Macromolecular Research
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• 제8권6호
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• pp.253-260
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• 2000

Biodegradable wafers were prepared with poly (hydroxybutyrate-co-hydroxyvalerate) (PHBV;5, 10, and 15 mole% for 3-hydroxyvalerate) by simple heat pressing method for the sustained release of antibiotic agent, gentamicin sulfate (GS) to investigate the possibility of the treatment for osteomyelitis. The effects of hydroxyvalerate (HV) content, thickness of wafers, various types of additives such as sodium dodecyl sulfate (SDS), microcrystalline cellulose, polyvinylpyrrolidone, and hydroxypropylcellulose (HPC), and different initial drug loading ratio on the release profile have been investigated. In vitro release studies showed that different release patterns and rates could be achieved by simply modifying factors in the preparation conditions. PHBV wafers with 3 mm thickness, 10% of GS initial loading, 15% of HV content and addition of 5% of SDS and HPC were free from initial burst and a near-zero-order sustained release was observed for over 30 days. It might be suggested that the mechanisms of G5 release may be more predominant simple dissolution and diffusion of GS than erosion of PHBV in our system.

• Archives of Pharmacal Research
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• 제18권3호
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• pp.183-188
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• 1995

Polymeric reinforcement and coatings of alginate beads were carried out to control the release rate of drug from alginate beads. A poorly water-soluble ibuprofen (IPF) was selected as a model drug. A commercially available $Eudragit^{\circledR}$ RS100 was also used as a polymer. Effects of polymeric contents, the presence of plasticizers and amount of drug loading on the release rate of drug were investigated. The release rate of drug from alginate beads in the simulated gastric fluid did not occur within 2 h but released immediately when dissolution media were switched to the simulated intestinal fluid. No significant difference of release rate from polymer-reinforced alginate bead without plasticizers was observed when compared to plain (simple) beads. However, the release rate of drug from polymer-reinforced alginate beads was further sustained and retarded when aluminium tristearate (AT) as a plasticizer was added to polymer. However, polyethylene glycol 400 (PEG400) did not change the release rate of drug from alginate beads although PEG400 was used to improve dispersion of polymer and sodium alginate, and plasticize $Eudragit^{\circledR}$ RS100 polymer. The presence of plasticizer was crucial to reinforce alginate gel matrices using a polymer. As the amount of drug loading increased, the release rate of drug increased as a result of decreasing effects of polymer contents in matrices. The significantly sustained release of drug from polymer-coated alginate beads occurred as the amount of polymer increased because the thickness of coated membrane increased so that cracks and pores of the outer surface of alginate beads could be reduced. The sustained and retarded action of polymer-reinforced and coated beads may result from the disturbance of swelling and erosion (disintegration) of alginate beads. From these findings, polymeric-reinforcement and coatings of alginate gel beads can provide an advanced delivery system by retarding the release rate of various drugs.