• 디지털콘텐츠학회 논문지
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• 제11권1호
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• pp.73-78
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• 2010

PROPELLER 확산강조영상기법이 금속에 의해 발생한 magnetic susceptibility artifact를 제거 할 수 있는지를 알아보고자 하였다. 뇌 MRI를 촬영한 환자 중에서 치아에 금속성 이물질을 가지고 있는 환자 20명을 대상으로 3.0T MR scanner를 이용하여 b value 0, 1000 s/mm2을 기준으로 에코 평면확산강조영상, PROPELLER 확산강조영상과 각각의 ADC map영상을 획득한 후 양쪽 측두엽, 뇌교, 안와등 네 부위에서 발생한 magnetic susceptibility artifact의 발생률을 비교 하였다.에코평면 확산강조영상 기법에서 금속물질이 있는 경우 magnetic susceptibility artifact가 발생되어 진단에 큰 제한점을 두었지만 PROPELLER 확산강조영상기법은 magnetic susceptibility artifact를 감소함으로써 임상적으로 정확한 진단에 도움이 될 것으로 생각된다.

• Investigative Magnetic Resonance Imaging
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• 제19권3호
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• pp.146-152
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• 2015

Purpose: The purpose of this study was to evaluate the associated brain parenchymal abnormalities of developmental venous anomalies (DVA) with susceptibility-weighted image (SWI). Materials and Methods: Between January 2012 and June 2013, 2356 patients underwent brain MR examinations with contrast enhancement. We retrospectively reviewed their MR examinations and data were collected as per the following criteria: incidence, locations, and associated parenchymal signal abnormalities of DVAs on T2-weighted image, fluid-attenuated inversion recovery (FLAIR), and SWI. Contrast enhanced T1-weighted image was used to diagnose DVA. Results: Of the 2356 patients examined, 57 DVAs were detected in 57 patients (2.4%); 47 (82.4%) were in either lobe of the supratentorial brain, 9 (15.7%) were in the cerebellum, and 1 (1.7%) was in the pons. Of the 57 DVAs identified, 20 (35.1%) had associated parenchymal abnormalities in the drainage area. Among the 20 DVAs which had associated parenchymal abnormalities, 13 showed hemorrhagic foci on SWI, and 7 demonstrated only increased parenchymal signal abnormalities on T2-weighted and FLAIR images. In 5 of the 13 patients (38.5%) who had hemorrhagic foci, the hemorrhagic lesions were demonstrated only on SWI. Conclusion: The overall incidence of DVAs was 2.4%. Parenchymal abnormalities were associated with DVAs in 35.1% of the cases. On SWI, hemorrhage was detected in 22.8% of DVAs. Thus, we conclude that SWI might give a potential for understanding of the pathophysiology of parenchymal abnormalities in DVAs.

• 대한방사선기술학회지:방사선기술과학
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• 제44권1호
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• pp.25-30
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• 2021

The purpose was to reduce the distortion of the image that occurs in the temporal bone area due to the very strong differences in susceptibility. A new SS-TSE technique was applied when examining the diffusion-weighted image of the temporal bone, where the auditory and facial nerves to be imaged were very thin and were adjacent to the cranial base including bone and air. This study was conducted from March 2020 to August of the same year, targeting 32 subjects who underwent the diffusion-weighted imaging of the temporal bone. To compare the distortion, existing SS-EPI technique and the new SS-TSE technique were both applied on the temporal bone area. As a result of the study, applying the new SS-TSE technique appeared to lower the distortion of images by 87.44, 46.13 and 42.35 % on the b-value 0, 800 and the ADC images, respectively. In conclusion, when using the new SS-TSE technique on the temporal bone DWI, distortion can be reduced, and thus images with high diagnostic value can be obtained.

• Investigative Magnetic Resonance Imaging
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• 제22권2호
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• pp.131-134
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• 2018

Susceptibility-weighted imaging (SWI) is well known for detecting the presence of hemorrhagic transformation, microbleeds and the susceptibility of vessel signs in acute ischemic stroke. But in some cases, it can provide the tissue perfusion state as well. We describe a case of a patient with hyperacute ischemic infarction that had a slightly hypodense, patchy lesion at the left thalamus on the initial SWI, with a left proximal posterior cerebral artery occlusion on a magnetic resonance (MR) angiography and delayed time-to-peak on an MR perfusion performed two hours after symptom onset. No obvious abnormal signals at any intensity were found on the initial diffusion-weighted imaging (DWI). On a follow-up MR image (MRI), an acute ischemic infarction was seen on DWI, which is the same location as the lesion on SWI. The hypointensity on the initial SWI reflects the susceptibility artifact caused by an increased deoxyhemoglobin in the affected tissue and vessels, which reflects the hypoperfusion state due to decreasing arterial flow. It precedes the signal change on DWI that reflects a cytotoxic edema. This case highlights that, in some hyperacute stages of ischemic stroke, hypointensity on an SWI may be a finding before the hyperintensity is seen on a DWI.

• Journal of Korean Neurosurgical Society
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• 제46권4호
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• pp.365-369
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• 2009

Objective : Susceptibility-weighted image (SWI) is a sensitive magnetic resonance image (MRI) technique to detect cerebral microbleeds (MBLs). which would not be detected by conventional MRI. We performed SWI to detect MBLs and investigated its usefulness in the evaluation of mild traumatic brain injury (MTBI) patients. Methods : From December 2006 to June 2007, twenty-one MTBI patients without any parenchymal hemorrhage on conventional MRI were selected. Forty-two patients without trauma were selected for control group. According to the presence of MBLs, we divided the MTBI group into MBLs positive [SWI (+)] and negative [SWI (-)] group. Regional distribution of MBLs and clinical factors were compared between groups. Results : Fifty-one MBLs appeared in 16 patients of SWI (+) group and 16 MBLs in 10 patients of control group [control (+)], respectively. In SWI (+) group, MBLs were located more frequently in white matters than in deep nucleus different from the control (+) group (p<0.05). Nine patients (56.3%) of SW (+) group had various neurological deficits (disorientation in 4, visual field defect in 2, hearing difficulty in 2 and Parkinson syndrome in 1). Initial Glasgow Coma Scale (GCS)/mean Glasgow Outcome Scale (GOS) were $13.9{\pm}1.5/4.7{\pm}0.8$ and $15.0{\pm}0.0/5.0{\pm}0.0$ in SWI (+) and SWI (-) groups, respectively (p<0.05). Conclusion : Traumatic cerebral MBLs showed characteristic regional distribution, and seemed to have an importance on the initial neurological status and the prognosis. SWI is useful for detection of traumatic cerebral MBLs, and can provide etiologic evidences for some post-traumatic neurologic deficits which were unexplainable with conventional MRI.

• Investigative Magnetic Resonance Imaging
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• 제23권1호
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• pp.70-74
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• 2019

Cerebral air embolism (CAE) is a rare complication of various medical procedures. It manifests with symptoms similar to those of typical acute cerebral infarction, however the treatment is quite different. We present a case of arterial CAE that was associated with a disconnected central venous catheter and appeared as punctate dark signal intensities with aliasing artifacts on the susceptibility-weighted filtered phase magnetic resonance image. The susceptibility-weighted filtered phase image can be helpful for diagnosing CAE and the magnetic resonance imaging reflects the pathophysiology of CAE.

• Investigative Magnetic Resonance Imaging
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• 제18권4호
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• pp.290-302
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• 2014

목적: 자화율 강조 자기공명영상 (Susceptibility-weighted imaging)은 혈액분해산물, 석회화, 철 침착물을 발견하는데 있어 높은 민감도를 보이는 3D spoiled gradient-echo pulse sequence 이다. 본 임상화보는 자화율 강조 자기공명영상의 주된 임상적 적용에 대해 설명하고 논의하는 데에 그 목적이 있다. 대상과 방법: 자화율 강조 자기공명영상은 자기강도영상 (magnitude image)과 위상영상 (phase image)을 이용한 고해상도, 3D fully velocity-compensated gradient-echo sequence 에 기초를 두고 있다. 정맥 구조물의 가시성을 향상시키기 위해, 자기강도영상은 여과된 위상 데이터 (phase data) 로부터 발생된 위상 마스크 (phase mask)를 이용해 증폭되고, 이것은 최소강도투사 (Minimal intensive projection) 알고리즘을 이용한 3D dataset 후처리 과정을 거치게 된다. 3T 자기공명기기에서 SWI를 포함하는 자기공명영상 검사를 시행한 총 200명의 환자를 대상으로 연구하였다. 결과: 자화율 강조 자기공명영상은 다양한 뇌 질환의 발견에 매우 유용하였다. 200명의 환자 중 80명은 선천성 정맥 기형, 22명은 해면상 혈관종, 12명은 다양한 질환에서의 석회화, 21명은 혈관자화 징후 (susceptibility vessel sign) 또는 미세출혈을 동반하는 뇌혈관 질환, 52명은 뇌종양, 2명은 미만성 축삭 손상, 3명은 동정맥 기형, 5명은 뇌경막 동정맥루, 1명은 모야모야병, 그리고 2명은 파킨슨병이 관찰되었다. 결론: 자화율 강조 자기공명영상은 미세 저혈량 혈관성 병변, 석회화 그리고 미세출혈과 다양한 뇌병변의 진단에 유용하다.

• Investigative Magnetic Resonance Imaging
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• 제19권2호
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• pp.107-113
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• 2015

Purpose: Susceptibility weighted imaging (SWI) is a new magnetic resonance technique that can exploit the magnetic susceptibility differences of various tissues. Intracranial hemorrhage (ICH) looks a dark blooming on the magnitude images of SWI. However, the pattern of ICH on phase images is not well known. The purpose of this study is to characterize hemorrhagic lesions on the phase images of SWI. Materials and Methods: We retrospectively enrolled patients with ICH, who underwent both SWI and precontrast CT, between 2012 and 2013 (n = 95). An SWI was taken, using the 3-tesla system. A phase map was generated after postprocessing. Cases with an intracranial hemorrhage were reviewed by an experienced neuroradiologist and a trainee radiologist, with 10 years and 3 years of experience, respectively. The types and stages of the hemorrhages were determined in correlation with the precontrast CT, the T1- and T2-weighted images, and the FLAIR images. The size of the hemorrhage was measured by a one- directional axis on a magnitude image of SWI. The phase values of the ICH were qualitatively evaluated: hypo-, iso-, and hyper-intensity. We summarized the imaging features of the intracranial hemorrhage on the phase map of the SWI. Results: Four types of hemorrhage are observed: subdural and epidural; subarachnoid; parenchymal hemorrhage; and microbleed. The stages of the ICH were classified into 4 groups: acute (n = 34); early subacute (n = 11); late subacute (n = 15); chronic (n = 8); stage-unknown microbleeds (n = 27). The acute and early subacute hemorrhage showed heterogeneous mixed hyper-, iso-, and hypo-signal intensity; the late subacute hemorrhage showed homogeneous hyper-intensity, and the chronic hemorrhage showed a shrunken iso-signal intensity with the hyper-signal rim. All acute subarachnoid hemorrhages showed a homogeneous hyper-signal intensity. All parenchymal hemorrhages (> 3 mm) showed a dipole artifact on the phase images; however, microbleeds of less than 3 mm showed no dipole artifact. Larger hematomas showed a heterogeneous mixture of hyper-, iso-, and hypo-signal intensities. Conclusion: The pattern of the phase value of the SWI showed difference, according to the type, stage, and size.

• 디지털콘텐츠학회 논문지
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• 제14권2호
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• pp.275-282
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• 2013

의료 영상처리 분야에서의 일반적인 객체 인식 방법은 픽셀들의 밝기 정보, 형태 정보, 패턴 정보 등 다양한 컴퓨팅 처리 방법으로 수행되어 진다. 그러나 컴퓨팅 방법에 사용되는 다양한 정보들이 의미가 없을 경우 객체인식에 많은 제약이 따르게 된다. 따라서 본 논문은 이러한 컴퓨팅 처리의 근본적인 제약사항을 해결하고자, MR 의료 영상에서의 물리적인 이론에 기반한 영상처리 방법을 전처리에 활용하고자 한다. 제안된 방법은 대비 개선 작업을 주된 목적으로 하는 SWI(Susceptibility Weighted Imaging) 처리를 통해 의미 있는 전처리 작업을 수행하고, 이에 대한 결과를 텍스처 분석을 통해 MR 뇌 영상의 회백질을 효과적으로 검출하는 과정으로 구성된다. 실험결과 제안 방법은 평균 영역차이가 5.2%로 기존의 대표적인 영역분할 방법에 비해 보다 효율적임을 증명하였다.

• 대한디지털의료영상학회논문지
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• 제15권1호
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• pp.27-31
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• 2013

Perfusion MR imaging is how to use exogenous and endogenous contrast agent. Exogenous perfusion MRI methods which are dynamic susceptibility contrast using $T2^*$ effect and dynamic contrast-enhanced using T1 weighted image after injection contrast media. An endogenous perfusion MRI method which is arterial spin labeling using arterial blood flow in body. In order to exam perfusion MRI in human, technical access are very important according to disease conditions. For instance, dynamic susceptibility contrast is used in patients with acute stroke because of short exam time, while dynamic susceptibility contrast or dynamic contrast enhancement provides the various perfusion information for patients with tumor, vascular stenosis. Arterial spin labeling is useful for children, women who are expected to be pregnant. In this regard, perfusion MR imaging is required to understanding, and the author would like to share information with clinical users