• 대한핵의학회지
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• 제11권1호
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• pp.3-8
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• 1977

Effect of sodium restriction with or without potassium supplement and furosemide diuresis on plasma aldosterone response to mild hemorrhage were studied in normotensive young volunteers. After an overnight fast, blood were drawn just before and 10, 20, 30, 50, 70, 90, and 120 minutes after the $^3H$-aldosterone injection. The sum of blood delivered reached over 100ml(during two hours). Plasma aldosterone and renin were measured by means of radioimmunoassay. The results were as followed; 1. Hemorrhage resulted in a moderate increase in plasma aldosterone level of volunteers with normal diet. 2. The mean figures of plasma aldosterone in subjects with sodium restriction and diuresis were likewise significantly increased by hemorrhage, however, the figure of the subjects with potassium supplement who already shown higher plasma level was without effect on hemorrhage. 3. Hemorrhage produced slight decrease in serum sodium concentration in every experimental conditions, although the changes were not significant. 4. Plasma renin activities after the hemorrhage followed a similar pattern with that of aldosterone, increased during sodium restriction or diuresis and unaffected during potassium supplement.

• Nutritional Sciences
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• 제9권4호
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• pp.273-279
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• 2006

The purpose of this study was to determine the independent and the combined effects of cell cultured Acanthopanax senticosus extracts (ASE) supplementation and swimming exercise on body weight, lipid profile, carnitine and leptin levels in C57 BL/6J mice. Forty C57BL/6J mice were divided into four groups: non-supplement and non-exercise (NSNE); non-supplement and exercise (NSE); supplement and non-exercise (SNE); supplement and exercise (SE) mice. They were allowed free access to food and water. The exercised groups were forced to swim (1hr, 6 days a week) in a water bath for 12 weeks. The supplemented groups were fed Cell cultured ASE (0.5 g/kg body weight/day) for 12 weeks. In this study, we found that the combination of Cell cultured ASE supplementation and exercise significantly decreased liver triglyceride (TG) level and serum leptin level but significantly increased serum HDL-cholesterol level compare to control (NSNE) group. These improved lipid profiles and decreased serum leptin would have positive effects on obesity and cardiovascular disease.

• 한국식품영양학회지
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• 제35권5호
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• pp.295-301
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• 2022

The medicines for treating osteoporosis currently in use have minor to severe side effects, and can be financially burdensome. Thus, there is a need for prevention and alternative supplement that is relatively inexpensive, and can be easily consumed daily as an alternative dietary therapy. In this study, bone marrow density of the spine and femur of osteoporosis patients were checked before and after consuming complex composed of calcium and magnesium, considered to be the core of bone mineral content. November 2017-November 2021, patients with T-score of less than -2.5 or -1.0 < T-score < -2.5 with history of fractures or recent fractures were enrolled. The data of 60 patients who orally administered Ionized Cal/Mag^TM Complex were reviewed retrospectively, and it was significantly confirmed that the average value of T-score was up-regulated by 0.5. Additionally, the cumulative dose was observed to have a positive effect, on the improvement of BMD in the 2nd Lumbar and Femur neck. It is expected that better results will be achieved if use of the supplement is continued.

• 식품보건융합연구
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• 제10권3호
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• pp.1-8
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• 2024

The global nutraceuticals market continues to grow due to rising income levels, increasing life expectancy, and a growing interest in personal health. Especially after the COVID-19 pandemic, the market for nutraceuticals has expanded rapidly with positive perceptions driven by increased attention to immune management for disease prevention. However, there is still a lack of research on the relationship between nutraceuticals and consumer behavior. This study aims to provide new insights into the dietary supplement market and help establish marketing strategies by analyzing consumer behavior toward dietary supplements in the post-COVID-19 era, focusing on Generation MZ. An online survey was conducted among consumers who have purchased dietary supplement products to test the hypotheses. The collected data were analyzed for validity and reliability using SPSS and AMOS programs. The results showed that the taste, price, brand, and design of dietary supplements significantly positively affect the satisfaction of MZ consumers. This study provides an in-depth understanding of the mechanisms of consumer behavior toward dietary supplements in the post-COVID-19 era, focusing on Generation MZ. By offering insights into consumers' health concerns and consumption behaviors, this study provides valuable perspectives on the future development of the market and helps companies develop effective strategies to meet consumer needs.

• Preventive Nutrition and Food Science
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• 제10권1호
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• pp.34-39
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• 2005

This study examined the anti-diabetic effect of a silkworm extract in C57BL/6J mice, an ob/㏈ model, fed a high fat diet for 8 weeks. The body weight was not significantly different with the silkworm-extract supplement, nor did food intake and body weight gains also did not differ significantly among the high-fat diet groups. However, the water intake by the silkworm-extract supplemented groups increased significantly compared with that by the distilled-water supplement group, nonetheless, the FER did not differ significantly. For all groups, the blood glucose increased the most after 30 minutes and yet returned to a fasting level within 90 minutes. The fasting time and resulting glucose tolerance for the silkworm-extract supplemented groups were significantly decreased compared to that for the high fat diet with distilled water supplement group, while the level of blood glucose in silkworm-extract supplemented groups was significantly decreased compared with than in the diabetic control group. The HbA1c and insulin levels were no different among the groups. The sucrase and lactase activities in the proximal small intestine were significantly decreased in the silkworm-extract supplement groups compared to that in the diabetic control group. There was no significant difference in the glycogen contents in the liver and muscle among the groups. In conclusion, it was found that the silkworm-extract supplement repressed the disaccharidase activity in the small intestines mucosa of the C57BL/6J mice.

• 한국음향학회지
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• 제33권1호
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• pp.68-74
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• 2014

이전 연구에서 퍼지 C-Means의 중심 데이터로 이루어진 보조 데이터를 이용한 히스토그램 등화기법을 제안하였다. 보조 데이터를 이용한 히스토그램 등화기법은 사용하는 참조 집합의 크기에 따라 화자 식별 성능에 영향을 받는다. 그러나 인식 시점에서 최적의 파라미터를 찾기는 어렵다. 이 문제를 해결하기 위해 본 논문에서는 화자 식별을 위한 다수 투표 방식에 기반을 둔 보조 데이터를 이용한 히스토그램 등화기법을 제안한다. 다수 투표 기반의 제안한 방법은 여러 종류의 보조 데이터를 이용한 히스토그램 등화기법으로 입력 음성을 분류한다. 본 연구에서 제안한 방법을 CMN(Cepstral Mean Normalization), MVN(Mean and Variance Normalization), HEQ(Histogram Equalization)와 같은 기존의 특징 정규화 방법 및 보조 데이터를 이용한 히스토그램 등화기법과 비교한다.

• Asian-Australasian Journal of Animal Sciences
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• 제16권2호
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• pp.227-233
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• 2003

Two experiments were conducted to evaluate the effects of chromium (Cr) on the growth performance, bone trait, serum traits, and immune responses in broilers. The broilers were fed corn-soybean meal basal diet supplemented with Cr at level of 0(control), 200, 400, or 800 ppb in the form of chromium picolinate (CrPic). The broilers were fed treated diets for 6 weeks in Exp. 1, but the Cr supplement was removed for the last 3 weeks in Exp. 2. Exp. 1 showed that dietary supplement of Cr did not affect growth performance of the broiler, though improved feed efficiency (p<0.05) was observed during 0 to 3 weeks. Moreover, serum total (p<0.05) and HDL cholesterols (p<0.06) were significantly higher in pooled Cr added group at 6 weeks of age, however, the difference was not significant in Exp. 2. The pooled Cr added group in Exp.1 had significantly lower (p<0.05) alkaline phosphatase activity and higher (p<0.09) calcium at 3 weeks. Significantly lower phosphorus was also observed in Exp. 2. With continued supplement of Cr as in Exp. 1, the alkaline phosphatase activity maintained higher at 6 weeks, as opposed to significantly lower in Exp. 2, which had no further Cr supplement. Higher bone breaking strength was observed in 400 ppb Cr supplemented in Exp. 1, though not significantly different. Serum glucose and triglyceride were not affected by Cr supplement. Antibody against Infectious Bronchitis (IB) was significantly (p<0.05) higher with 400 ppb Cr supplemented, and anti-Newcastle disease (ND) antibody also tended to be higher (p<0.06) in pooled Cr added group at 6 weeks of age in Exp. 1. Peripheral blood blastogenesis activity was not different among the treatments. The results suggest that diet supplemented with 400 ppb CrPic may be beneficial to the broiler.

• 한국식품영양과학회지
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• 제33권3호
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• pp.518-522
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• 2004

이에 본 연구에서는 한국인에 적합한 비만 개선책을 찾고자 지방흡수억제 기능과 과잉의 탄수화물 흡수 억제 기전이 함께 작용하는 방법으로서 강낭콩(white kidney bean, Phaseolus vulgaris)에서 $\alpha$-amylases 활성을 저해하는 탄수화물 흡수 억제하는 추출물과 지방산과 콜레스테롤 합성에 관여하는 효소의 저해제인 HCA(hydroxycitric acid)를 함유하여 지방 합성을 저해, 식욕 억제 효과와 지방의 분해 촉진을 유도하는 가르시니아 캄보지아(Garcinia cambogia), 그리고 배변 활동을 원활하게 하도록 도움을 주는 수용성 식이 섬유(microstalline cellulose) 등을 배합하여 비만 개선용 다이어트 식이 조성물을 제조한 후 임상 실험을 수행한 결과 체중과 체지방 지수에서 유의한 감소효과를 얻을 수 있었다. 이들 결과를 종합하면, 강낭콩 추출물인 파제올라민과 가르시니아 캄보지아 추출물의 지방 합성 저해 효과, 그리고 수용성 식이 섬유 등을 첨가하여 제조한 비만 개선용 다이어트 식이 조성물이 임상실험에서 체중 증가를 효과적으로 억제할 수 있음을 관찰할 수 있었으며, 이는 현대 성인 질병 가운데 하나인 비만을 효과적으로 예방, 치료할 수 있는 다이어트 식이로 유용할 것으로 사료된다.

• 대한한의학원전학회지
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• 제21권3호
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• pp.285-296
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• 2008

"The Golden Mirror of Medicine(醫宗金鑑)" is a very famous medical book. It was compiled by the medical officers of the Cheong(淸, Qing) Dynasty, especially headed by Ogyeom(吳謙, Wuqian). "The Elimination ＆amp; Supplement about the Famous Prescription Comments(刪補名醫方論)"that forms one part of "The Golden Mirror of Medicine(醫宗金鑑)", is a collection of famous notes about important prescriptions. Many parts of "The Elimination ＆amp; Supplement about the Famous Prescription Comments(刪補名醫方論)" were quoted from "The Famous Prescription Comments on Ancient and Modern Times(古今名醫方論)". The first part of the vol. Ⅱ of "The Elimination ＆amp; Supplement about the Famous Prescription Comments(刪補名醫方論)"mainly describes about the prescriptions of elevating Yanggi[升陽], which were invented by Igo(李杲, Ligao), a famous physician of the Geum(金, Jin) Dynasty. The treatments were five and three of them were quoted from "The Famous Prescription Comments on Ancient and Modern Times(古今名醫方論)". The basic rule of herbal combination of these prescriptions is a combination of herbs of strengthening-gi[補氣] and dispersing herbs[發散藥]. If the dispersing herbs[發散藥] is used with the herbs of strengthening-gi[補氣藥], they elevate Yanggi(陽氣) together.

• Reproductive and Developmental Biology
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• 제36권3호
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• pp.141-145
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• 2012

The present study was conducted to develop a simple method for porcine oocyte maturation without $CO_2$ regulation. In experiment 1, we evaluated that the effect of $CO_2$ non-supplement on porcine oocyte maturation. Cumulusoocyte complexes (COCs) were collected from 2~6 mm follicles and divided into three groups (Control, tube-$CO_2$, and tube-non-$CO_2$). For control, COCs were cultured in 4-well multidish in a $CO_2$ incubator. For tube-$CO_2$, COCs were cultured in a round-bottom tube in a $CO_2$ incubator, and for tube-non-$CO_2$, COCs were cultured in a round-bottom tube sealed tightly without $CO_2$ supplement in a dry incubator. The proportion of oocytes reached to metaphase II (M-II) was not significantly different among three groups (87.9% to 91.4%). In experiment 2, we evaluated the effect of $CO_2$ non-supplement during oocyte maturation on development of embryos. Oocytes with a polar body were divided into two groups (Control and tube-non-$CO_2$) and applied 1.1 kV/cm or 1.2 kV/cm voltages for parthenogenetic activation. After activation, embryos were cultured for 6 days and examined the development. The proportion of embryos cleaved was not significantly different among treatment (86.3% to 91.5%). The proportion of embryo reached to blastocyst stage was not significantly different among treatment (13.9% to 25.2%). The cell number of blastocysts was not significantly different among treatment (29.0 to 32.4). In conclusion, oocytes cultured in a dry incubator without $CO_2$ supplement have enough competence to development after parthenogenetic activation. These results would be useful for transporting oocytes or embryos a long distance.