• 대한임상독성학회지
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• 제13권1호
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• pp.33-35
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• 2015

A 24 year-old man attempted suicide by injection of 1 cc of thinner into his left antecubital vein; 3 hours later, he visited our emergency room because of left chest pain. We suspected a chemical pneumonitis based on the abnormal findings of his chest X-ray and computed tomography. On the 3rd day after admission, a cellulitis also occurred at the injection area. His symptoms were relieved after supportive care for 2 weeks. There is significant experience with intoxication of thinner inhalation, whereas intoxication of intravenous thinner is rare.

• 대한임상독성학회지
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• 제5권2호
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• pp.119-122
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• 2007

Paraquat poisoning is a fatal type of herbicide intoxication. It is characterized by multi-organ failure and pulmonary fibrosis with respiratory failure. Intravenous and intramuscular injection of paraquat is rarely described. However, We encountered two fatal cases of acute poisoning caused by paraquat injection. Two patients were admitted to our emergency unit after intravenous and intramuscular injection of 23.8% paraquat (about 476 mg of paraquat). A 37-year-old man diluted 2 ml of 23.8% paraquat solution with 1 ml of normal saline and injected it both intravenously into his left antecubital fossa and intramuscularly into his abdomen in a suicide attempt. He died 5 days later from respiratory failure and acute renal failure. A 92-year-old man was injected intravenously into his right antecubital fossa by his grandson with 2 ml of 23.8% paraquat solution diluted with 1 ml of normal saline. He died 2 days later from early circulatory collapse and multi-organ failure (metabolic acidosis, acute renal failure, coagulopathy). Intravenous and intramuscular injection with a small quantity of paraquat resulted in fatal toxicity in our patients.

• 대한임상독성학회지
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• 제11권1호
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• pp.31-35
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• 2013

Acute organophosphate intoxication is important because of its high morbidity and mortality. The mortality is still high despite the use of atropine as specific antidotal therapy and oximes for reactivation of acetylcholinesterase. Inhibition of acetylcholinesterase by organophosphate can cause acute parasympathetic system dysfunction, muscle weakness, seizure, coma, and respiratory failure. Acute alteration in conscious state or a coma, which may occur following organophosphate intoxication, is an indication of severe intoxication and poorer prognosis. This acute decline in conscious state often reverses when the cholinergic crisis settles; however, it may be prolonged in some patients. We report on a case of a 60-year-old male who showed prolonged decline in conscious state due to of Central Nervous System (CNS) toxicity after a suicide attempt with organophosphate.

• 대한임상독성학회지
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• 제3권2호
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• pp.103-106
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• 2005

BASTA is an herbicide which contains glufosinate ammonium as a main component with an anionic surfactant, polyoxyethylene alkylether sulfate, and nonselectively inhibits glutamine synthetase. It became a wildly used herbicide in Korea and its intoxication is now increasing. A 42-year old woman ingested about 300ml of BASTA in a suicide attempt. She showed unconsciousness and respiratory distress in the beginning, and later developed multiple generalized convulsions, low blood pressure, fever and diabetes insipidus. Although she became alert 12 days after the ingestion, she showed retrograde amnesia for a period of about recent 10 years. A neuropsychological test on day 22 revealed frontal lobe dysfunction, visual memory disturbance and slight decrease in visuospatial function. All these neurological abnormalities that might occur due to glufosinate ammonium were almost improved in the follow-up test performed a month later.

• 한국학교보건학회지
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• 제34권3호
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• pp.151-160
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• 2021

Purpose: The purpose of this study was to identify predictors of suicidal attempts in adolescents over 5 years after school dropout. Methods: The data of the Panel Survey of School Dropouts (of 2013 to 2017) conducted by the National Youth Policy Institute were analyzed. The analysis used the 2013 survey data as the baseline and examined suicidal attempts from 2013 to 2017. A total of 776 adolescents were included in the analysis. Descriptive statistics, 𝝌² test, t-test, and multiple logistic regression were carried out using SAS 9.2. Results: About 11% (87 out of 776) of the adolescents with an experience of dropout attempted suicide between 2013 and 2017. The risk of suicidal attempts was significantly lower in female (AOR: 0.57, 95% CI: 0.87~0.93) than in male adolescents. The higher the self-esteem, the lower the risk of suicidal attempts (AOR: 0.87. 95% CI: 0.78~0.97). The higher the depression level (AOR: 1.10, 95% CI: 1.05~1.16) and the rate of parental abuse (AOR: 1.09, 95% CI: 1.02~1.18), the higher the risk of suicidal attempts. Conclusion: The findings of the study suggest that those who are male, depressed, have low self-esteem or have been abused by their parents are at high risk of suicidal attempts among the adolescents with dropout experiences. Therefore, early intervention is necessary for those at high risk.

• 한국학교보건학회지
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• 제35권3호
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• pp.92-103
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• 2022

Purpose: The purpose of this study was to prepare basic data for education and policy proposals related to enhancement of happiness by identifying factors affecting the subjective happiness among Korean adolescents by family type. Methods: The study was a secondary analysis using the raw data of the 16th Youth Risk Behavior Web-based Survey (2020). A complex sample multiple logistic regression analysis was conducted to identify factors affecting adolescent happiness by family type. Results: As a result, the factors that commonly affect the subjective happiness of adolescents for all family types were identified as economic status, academic performance, perceived stress, and loneliness. Additional factors that affect the subjective happiness of adolescents of both Korean two-parent and single parent families were sleep and subjective health status. Financial assistance, number of toilets, breakfast, exercise, depression, suicidal ideation, and suicide attempt were also reported for Korean two-parent families. Conclusion: This study provided empirical basic data for enhancing adolescent happiness in consideration of priority targets and family composition characteristics by identifying factors affecting subjective happiness by family type. Adolescent happiness is a factor that should be actively pursued at home, school, and society, and it should be the goal of education for holistic growth of students.

• 한국보건간호학회지
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• 제37권1호
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• pp.125-135
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• 2023

Purpose: The number of patients suffering from depression is rapidly increasing worldwide, and by 2030, it is expected to pose a severe social and economic burden. Reports suggest that approximately 30% of subjects with symptoms of depression do not attempt treatment. Therefore, predicting the characteristics of subjects with depressive symptoms who have not even attempted counseling treatment is essential to increase the participation rate for such treatment. This study intends to predict the participation rates for psychological counseling treatment for depression among subjects with depressive symptoms. Methods: This study used data from the 2021 Korea Community Health Survey (KCHS). Data analysis was carried out using a decision tree to design a model that predicted participation in psychological counseling for depression. Results: The results showed that subjects aged 65 to 74 had difficulty understanding the explanations of medical staff even though they did not have cognitive impairment. Only 11.1% of this group received psychological counseling, which was the lowest rate among the various age groups. Among the subjects, 62.4% of those aged 19-44 or 45-64, who had suicidal thoughts and attempted suicide, received psychological counseling and this was the highest rate among the age groups surveyed. Conclusion: The identification of people showing depressive symptoms is crucial for encouraging them to undertake treatment. Also, proper depression-oriented medical services should be developed and implemented for people with depressive symptoms who exhibit a blind spot towards attempting treatment.

• 대한불안의학회지
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• 제19권2호
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• pp.56-60
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• 2023

Progressive supranuclear palsy (PSP) is rare atypical Parkinsonism accompanied by various psycho-behavioural problems. In this case report, we describe the diagnostic and treatment progress of a 65-year-old PSP patient who visited the psychiatric clinic with a depressed mood and lumbar pain resulting in a suicide attempt. Over the course of 30 months of treatment, typical characteristics of PSP, such as postural instability, dyskinesia, cognitive dysfunction and supranuclear gaze palsy, became prominent, and magnetic resonance imaging and the F-18 FP-CIT positron emission tomography revealed midbrain atrophy and reduced dopamine uptake in the basal ganglia. When treating elderly patients with depression, parkinsonism symptoms such as gait disturbances, frequent falls, tremors, and rigidity should be closely examined.

• 수면정신생리
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• 제20권1호
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• pp.22-30
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• 2013

목 적: 수면 문제는 지속적으로 성인의 자살 위험 요인으로 보고되어왔고 최근에는 청소년을 대상으로도 그 가능성이 보고되고 있다. 본 연구는 과거의 자살 행동 유무에 따라 대상군을 분류하여 이들 사이의 자살위험요인과 수면양상을 비교하고 자살위험요인으로써의 수면의 가능성을 평가해 보았다. 방 법: 고등학생 561명(남 271명, 여 290명)을 대상으로 자살위험행동 체크리스트, Center for Epidemiological Study-Depression(CES-D), Symptom Checklist-90-Revision(SCL-90-R) 불안, 공격성 하위척도, Pittsburg Sleep Quality Index(PSQI)가 시행되었다. 결 과: 46명(8.1%)이 자살시도 목적으로 자기 위해 행동을 한 경험이 있었고, 181명(32.4%)은 자살사고 경험만을 보고했다. 334명(59.5%)은 과거 자살위험행동(사고, 시도)을 보이지 않았다. 자살 위험군은 학교 폭력, 물질남용, 인터넷 중독, CES-D, SCL-90-R, PSQI에서 비자살 위험군에 비해 유의하게 점수가 높았다. 로지스틱 회귀분석의 결과 자살위험행동은 우울, 스트레스와 상관성을 보였고, PSQI에서는 수면 잠복기, 주간기능장애에서 상관성을 보였다. 일원분산분석(ANOVA, Analysis of variance)에서는 자살 시도군에서 수면 잠복기의 연장, PSQI 지수의 증가가 가장 심하게 관찰되었다. 결 론: 수면문제는 청소년군의 자살위험행동과 높은 연관성을 보인다. 특히 수면 잠복기, 주간기능장애가 자살위험행동의 중요한 인자일 것으로 여겨진다. 추후 부모, 교사, 의료인들에 의한 청소년의 수면에 대한 지속적인 평가와 관리를 권장하는 바이다.

• 대한임상독성학회지
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• 제5권1호
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• pp.36-42
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• 2007

Purpose: To assess the epidemiology and the clinical features of Glufosinate herbicide in Korea. Methods: Data was prospectively collected during 1 year since August 2005 from 38 hospital in Korea. We analyzed the epidemiologic characters and clinical manifestations of Glufosinate poisoning. In addition, the characteristics of patients with severe central nervous system toxicity were separately analyzed to find poor prognosis relating factors. Results: During study periods, there were 715 persons of poisoning of herbicides and insecticides. 6.3% (45 persons) of the agricultural chemicals poisoning had Glufosinate poisoning. There were 36 cases of suicide attempts and 7 cases of accidental exposure, The major of poisoning route was oral ingestion (44 cases). 28.9 % of the study patients had not toxic symptoms. The most common symptoms were gastrointestinal symptoms relating surfactant irritation. 67.7% of central nervous symptoms occurred lately. 10 persons showed severe central nervous system toxicity. 4 persons of them showed poor outcomes (1 death, 3 hopeless discharged). Complications of respiratory failure and renal failure related with poor outcome. Conclusion: Majority of patients ingested Glufosinate for suicide attempt. 22.2% of patients with Glufosinate poisoning showed delayed serious central nervous system toxicity. Early supportive care of altered mentality may prevent late respiratory complications and improve the outcomes.