• Psychiatry investigation
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• 제15권12호
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• pp.1174-1180
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• 2018

Objective Structural changes of brain areas have been reported in depressive disorder and suicidal behavior (SB), in which TPH1 also has been known as a promising candidate gene. We investigated gray matter volume (GMV) differences, TPH1 rs1800532 and rs1799913 polymorphisms previously found to be associated with depressive disorder and SB, and the relationship between the two markers. Methods Thirteen depressive disorder patients with suicidal attempts (SA) and twenty healthy controls were included. We examined GMV differences using a voxel-based morphometry and regions of interest analysis. Direct sequencing was used for genotyping. Results The patients showed significant GMV reduction in left cerebral region including middle frontal gyrus, inferior frontal gyrus, and anterior cingulate cortex; in right middle temporal gyrus; in left cerebellar tonsil; and in right cerebral region including precentral gyrus and postcentral gyrus (corrected p<0.005). The right precentral and postcentral gyri GMV values of AA and CA genotypes patients were significantly decreased compared to those of CC genotype subjects (corrected p=0.040). Conclusion These findings show the possibility that both GMV reductions and TPH1 rs1800532/rs1799913 A allele may be involved in the pathogenesis of depressive disorder patients with SA.

• 한국콘텐츠학회논문지
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• 제22권1호
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• pp.611-619
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• 2022

본 연구는 2017년, 2019년 국민건강영양조사 자료를 활용하여 1인 독거가구 중 우울증 및 자살생각에 영향을 미치는 요인에 대하여 분석하였다. 분석에 포함된 변수는 인구사회, 경제학적 변수, 건강상태 및 건강행동 변수를 고려하였다. 분석결과 우울증 유병은 활동제한 여부(OR: 4.753, p-value: <.0001), 현재흡연 여부(OR: 2.013, p-value: 0.044)와 통계적으로 유의한 관련성이 있었고, 자살생각은 가구소득(OR: 3.526, p-value: 0.043), 주관적 건강상태(OR: 2.945, p-value: 0.007), 활동제한(OR: 2.263, p-value: 0.003), 현재흡연 여부(OR: 2.000, p-value: 0.023)와 통계적으로 유의한 관련성이 있었다. 이처럼 1인 독거가구는 그 자체로 심리적 불안감을 가질 수 밖에 없고, 사회경제적, 신체적으로 위기에 처하여 정신건강 문제를 일으킬 수 밖에 없으므로 지역사회에서 사회적 네트워크 시스템을 구축하여 이들을 조기에 발견하여 적절한 중재를 통해 비관적 결과로 이어지지 않도록 해야할 것이다.

• 한국학교ㆍ지역보건교육학회지
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• 제24권3호
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• pp.23-35
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• 2023

Objectives: The purpose of this study is to examine the marital status, drinking behavior, and mental health characteristics of alcohol consumers, and to explore the relationship between marital status and mental health among alcohol consumers. Methods: The research data utilized raw data from the 8th Korea National Health and Nutrition Examination Survey (2020), Second Round. A total of 3,713 participants were included in the final analysis. Data analysis was performed using the statistical software SPSS version 26.0. Results: The relationship between the study participants and mental health revealed that compared to those with a spouse, individuals who were divorced or separated had an odds ratio (OR) of 2.598 for 'depression' and an OR of 2.142 for 'suicidal thoughts'. In the case of 'stress perception', individuals who were divorced or separated had an OR of 3.434. In terms of gender, females had an OR of 4.867 for 'depression', an OR of 2.510 for 'suicidal thoughts', and an OR of 1.847 for 'stress perception', compared to males. Regarding age, the odds of 'depression' were 1.801 times higher in the 60 to 79 age group compared to the 18 to 39 age group. For smoking status, smokers had an OR of 2.812 for 'depression' compared to non-smokers. The OR for 'suicidal thoughts' was 3.047, and the OR for 'stress perception' was 1.463. However, the relationship between mental health and binge drinking frequency and quantity of alcohol consumed in a single session was not significant. Conclusion: The divorced, separated, or bereaved groups may be vulnerable to 'depression,' 'suicidal ideation,' and 'stress.' Therefore, there is an expectation to explore strategies for the development and enhancement of community-based mental counseling and health education support programs, aiming to improve the mental well-being and quality of life of individuals and the local community.

• 대한치과기공학회지
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• 제44권1호
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• pp.15-23
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• 2022

Purpose: The purpose of this study was to identify the experiences of depression, suicidal thoughts, and habitual drug use in middle and high school students and examine their relationship with the oral symptoms experiences. Methods: The participants of this study were 54,948 middle and high school students who took the screening and health survey at the 16th "Youth Health Behavior Survey" (2020). The SPSS statistical software (IBM SPSS 23.0 for Windows; IBM) was used for data analysis. The significance level was set to 0.05. Results: Complex-sample logistic regression analysis was performed to confirm the relationship between the experiences of depression, suicidal thoughts, and habitual drug use and oral symptom experienced. The results indicated that the absence of depression, suicidal thoughts, or habitual drugs had a significant effect on oral symptom experience. Conclusion: A systematic counseling program for early detection of oral symptoms and oral health promotion as well as strategies for practicing correct oral hygiene are required. Additionally, it is necessary to develop a customized education program to promote health education in middle and high school students. It can be used as the basis for an integrated support system that students can use to grow healthy. A differentiated program on the topic of mental health promotion for each grade can be planned and its effects can be monitored.

• 보건교육건강증진학회지
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• 제28권5호
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• pp.61-71
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• 2011

Objectives: This study aims to identify differences in problem gambling among Korean university students by gender and to analyze the relationship between problem gambling and health risk behaviors. Methods: With a sample of 2,026 4-year university students, a questionnaire included CPGI (Canadian Problem Gambling Index) scale and health risk behavior items was administered. Descriptive statistics, t-test, and ANOVA were performed on the data. Results: The prevalence of gambling addiction of male students(14.6%) was two times higher than that of female students(6.6%). The severity of problem gambling was higher in: smokers, those with drug use experience, heavy drinkers, and those with frequently recurring suicidal thoughts, respectively. Conclusions: This study suggests that the problem gambling of university students is a complicated and comprehensive public health problem that is related with health risk behaviors such as alcohol drinking, smoking, drug use, and suicidal thoughts. Prevention strategies and policies are suggested based on the study results.

• 생물정신의학
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• 제6권1호
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• pp.81-88
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• 1999

자살 시도군 21명, 우울증 환자군 14명, 그리고 정상 대조군 10명을 대상으로 혈소판내 세로토닌의 농도, 반 구조화된 설문조사, 다면적 인성검사, HAM-D, 충동성 검사를 시행하여 비교한 결과는 다음과 같았으며, 자살 시도군의 자살방법은 대부분 농약 중독이었다. 1) 자살 시도자의 남녀 비는 차이가 없었다. 2) 혈소판내의 세로토닌의 농도는 자살 시도군, 우울증 환자군 및 정상 대조군간에 차이가 없었다. 3) 다면적 인성검사 결과는 자살 시도군의 경우 D, Hs, Pt 척도가 높았으며, 우울증 환자군의 경우 D, Pa, Si 척도가 높았다. 4) HAM-D 점수는 우울증 환자군과 자살 시도군 모두에서 높았으며, 특히 우울증 환자군의 경우 더 의미 있게 높았다. 5) 충동성 검사 결과는 자살 시도군이 우울증 환자군에 비하여 무계획 충동성, 운동 충동성이 의미 있게 높았다.

• 생물정신의학
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• 제6권2호
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• pp.227-234
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• 1999

자살 시도군 231명, 환자 대조군 231명, 정상대조군 231명을 대상으로 혈청 콜레스테롤 농도를 측정하여 다음의 결과를 얻었다. 1) 자살 시도군이 환자대조군 혹은 정상대조군보다 혈청 콜레스테롤 농도의 유의한 저하를 보였다. 2) 진단별로는 우울증과 인격장애에서 자살 시도군이 환자대조군보다 콜레스테롤 농도의 유의한 저하를 보였으나, 정신분열병과 양극성 정동장애 조증형에선 차이가 없었다. 3) 자살 시도군의 남녀별로 비교시, 남자가 여자보다 콜레스테롤 농도의 유의한 저하를 보였으며, 진단별로는 우울증에서만 유의한 차이를 보였다. 4) 자살 시도군에서 낮은 콜레스테롤 농도는 심각한 자살 수행과 연관성이 있었다. 5) 자살 시도군에서 치료전에 비해 치료후 혈청 콜레스테롤 농도의 유의한 증가를 보였다. 본 연구의 결과는 자살 시도의 예측인자로서 혈청 콜레스테롤이 이용될 수 있음을 시사한다. 향후 콜레스테롤 농도에 미치는 변인들을 통제한 전향적 방법을 통해 원인적 측면에서 혈청 콜레스테롤 농도와 세로토닌, 인터루킨-2, 멜라토닌 간의 연관성에 관한 연구가 이루어져야 하겠다.

• 한국콘텐츠학회논문지
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• 제12권12호
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• pp.672-682
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• 2012

이 연구는 최근 노인들의 스트레스와 우울, 자살생각 등 정신건강 폐해의 심각성을 인지하고 이에 영향을 미칠 것으로 예상되는 삶의 질, 건강행태, 건강수준 등과 정신건강 간의 구조적인 관계를 검증하고자 수행하였다. 연구 자료는 전 국민을 모집단으로 체계적인 표본조사를 실시한 2009년 국민건강영양조사의 원자료에서 65세 이상 노인들 중 연구에 적합한 1,490명을 최종 연구대상자로 선정하였다. 연구결과 첫째, 노인들의 삶의 질이 높을수록 스트레스, 우울, 그리고 자살생각 등을 감소시키는 효과가 있었다. 또한 삶의 질은 건강수준을 강화시켜 정신건강을 증진시키는 효과가 있었다. 둘째, 흡연, 문제음주, 비만, 적당한 운동과 수면 등으로 측정한 건강행태가 정신건강에 직접적인 영향은 없었으나, 건강수준을 매개로 한 간접효과를 확인하였다. 이 연구결과를 기반으로 노인의 정신건강 증진을 위해서는 삶의 질 제고를 우선적으로 고려하면서, 건강행태를 변화시키려는 체계적인 노력이 중요하다 하겠다.

• 한국학교보건학회지
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• 제35권3호
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• pp.65-74
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• 2022

Purpose: The purpose of the study was to verify the degree of smoking behaviors including conventional cigarettes, electronic cigarettes, and dual use of conventional and electronic cigarettes among adolescents, and to explore associated intrapersonal and interpersonal factors of the three smoking behavior groups. Methods: The secondary data analysis was performed using the 17th 2021 Korea Youth Risk Behavior Survey. The types of smoking behaviors were grouped into conventional cigarettes, electronic cigarettes, and dual use for data analysis. Descriptive statistics and a χ² test were performed. Multinomial logistic regression analysis was conducted to identify factors associated with of the three smoking behavior groups. Results: Among the 54,848 adolescents, 3.6%, 1.2% and 6.2% were involved in conventional cigarettes, electronic cigarettes, and the dual use, respectively. The factors associated with the three types of smoking behaviors were depression, suicidal ideation, having a smoking mother, having smoking brothers or sisters, and having smoking friends. Recovery from fatigue by sleep was associated with the dual use of conventional and electronic cigarettes. Anxiety was associated with conventional cigarettes. Having a smoking father was associated with conventional cigarettes and dual use. Conclusion: A significant number of adolescents were involved in not only the use of conventional or electronic cigarettes, but also dual use of them. Adolescents who had depression, suicidal ideation, having a smoking friend, and having a smoking family member were more likely to be involved in the three types of smoking behaviors. Customized interventions to decrease smoking should be developed considering intrapersonal factors as well as interpersonal factors.

• International Journal of Human Ecology
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• 제17권1호
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• pp.27-37
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• 2016

This study was to understand associated factors with frequent exposure to Internet pornography among Korean adolescents. We used data (N = 45,783) from the 2012 Korea Youth Risk Behavior Web-based Survey to examine demographics, family environmental variables, Internet use time, mental health indicators, sexual behavior, and delinquency among Korean adolescents identified as frequent users of Internet pornography. Multiple logistic regression analysis revealed that frequent users of Internet pornography were more likely to be older males with differences in living arrangements and perceived economic status of the family. They were heavy Internet users with mental health issues, such as a higher likelihood of sadness, suicidal ideation, suicide attempts, high stress, and a lower likelihood of feeling happiness. Their higher probability of exploratory (OR =1.79-4.60), and high-risk sexual behavior (OR = 2.20-7.46), and other delinquencies (OR = 1.74-7.68) requires more attention from public health professionals.