• Title/Summary/Keyword: Substituents

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Reactions of Trichloroethylideneacetophenone with Hydrazines (II) (Trichloroethylideneacetophenone과 Hydrazine 들의 반응 (II))

  • Youn Young Lee
    • Journal of the Korean Chemical Society
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    • v.16 no.3
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    • pp.189-192
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    • 1972
  • 2, 6-Disubstituted-3-pyridazinones were synthesized from the reaction of trichloroethylideneacetophenone with substituted phenylhydrazines. Trichloroethylideneacetophenone 2, 4-dinitrophenylhydrazone was isolated from the reaction of trichloroethylideneacetophenone with 2, 4-dinitrophenylhydrazine and it gave 2-(2, 4-dinitrophenyl)-6-phenyl-3-pyridazinone through ring closure. This indicates that pyridazinones are produced through hydrazone formation and ring closure as suggested previously. The effect of substituents of phenylhydrazine on the reaction was also discussed.

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Studies on the Synthesis of Naphthoquinoids

  • Park, Oee-Sook;Kim, Ju-Cheun
    • Archives of Pharmacal Research
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    • v.21 no.3
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    • pp.326-329
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    • 1998
  • Four derivatives of 6-oxo-3,4,4a,5-tetrahydro-3-hydroxy-2,2-dimethylnaphtho-1,2-pyran (1), known as bacterial, bacteriostatic, fungicidal, fungistatic agents, were synthesized to investigate the effect of substituents on the aromatic ring.

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Application of Molecular Descriptor for Prediction and Analysis of the Affinity between Alkyl Substituted Super Hydrophobic Dyes and Polypropylene Fibers (폴리프로필렌 섬유용 알킬치환 초소수성 염료의 친화력 분석과 예측을 위한 Molecular Descriptor의 활용)

  • Jang, Gyeong-Jin;Jeong, Jong-Seok;Kim, Tae-Gyeong
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2008.10a
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    • pp.77-78
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    • 2008
  • Affinity between alkyl substituted super hydrophobic dyes and polypropylene fiber has been analyzed by using the molecular descriptor as a method to predict chemical and physical characteristics of compounds. Hydrophobicity of synthesized dyes calculated by LogP which is one of molecular descriptors was increased continuously as the length of alkyl substituents increased.

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Furo[3,2-h]quinoline Derivatives as a Gastric H+/K+-ATPase Inhibitors

  • Kang, Seung-Kyu;Cho, Sung-Yun;Kim, Sung-Soo;Cheon, Hyae-Gyeong;Choi, Joong-Kwon;Yum, Eul-Kgun
    • Bulletin of the Korean Chemical Society
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    • v.23 no.3
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    • pp.454-458
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    • 2002
  • Furo[3,2-h]quinoline derivatives were synthesized as a gastric $H^+$/$K^+$-ATPase inhibitors. The oxycyclization of 7 and 8-positions in quinoline potentiated the inhibitory activity, while no significant changes in biological activity were observed by the variation of substituents in furan ring. The several furo[3,2-h]quinoline derivatives were worthy of in vivo investigation for their anti-secretory and anti-ulcer activity.

OPTICAL SPECTRA OF 2-AROYL-5-AROYLAMINO DERIVATIVES OF 2H-1,2,4-THIADIAZOLINE-3-ONE

  • Choi, Myung-Jin;Ra, Chan-Soo
    • Journal of Photoscience
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    • v.1 no.2
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    • pp.131-133
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    • 1994
  • Optical spectra of 5-amino-2H-1, 2, 4-thiadiazoline-3-one (AT) and some 2-aroyl-5-aroylamino derivatives are reported. Absorption spectra of 2-aroyl-5-aroylamino derivatives show bathochromic shift due to AT group and other substituents of phenyi ring. Weak emission is observed for some derivatives.

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Poly(fluorene)s for LED Applications

  • Lee, Jeong-Ik;Zyung, Tae-Hyoung;Klaerner, Gerrit;Miller, Robert D.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2000.01a
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    • pp.129-130
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    • 2000
  • The emission color stability of poly(fluorene) derivatives upon thermal annealing or passage of current in an electroluminescent device is affected by the structure of the main chain polymer unit and particularly by the polymer chain end substituents. Proper attention to these features leads to colorfast blue emission in both photo- and electoluminescence. Furthermore, the spectral emission characteristics can be tuned by the incorporation of various comonomers. Preliminary single layer device studies validate the potential utility of poly(fluorene) homo and copolymers for OLED applications.

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Bromolactonization of 2-Substituted-1-Cyclohexenyl-1-acetic acid (2-치환-1-Cyclohexenyl-1-acetic acid의 브롬락톤화 반응)

  • Jew, Sang-Sup
    • YAKHAK HOEJI
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    • v.33 no.3
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    • pp.206-210
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    • 1989
  • Bromolactonization of 2-Substituted-1-cyclohexenyl-1-acetic acid (1) with 1,3-dibromo-5,5-dimethylhydantoin (dibromantin) in N,N-dimethylformamide gave the corresponding ${\gamma}-bromo-{\beta}-lactone$ (2) and ${\beta}-bromo-{\gamma}-lactone$ (3). The effect of the substituents, the reaction temperature, and the solvent on the regioselectivity was discussed.

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Synthesis and Antibacterial Activity of New Cephalosporins with Lactonyloxyimino Moiety

  • Suh, Kwee-Hyun;Park, Joo-Woong
    • Archives of Pharmacal Research
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    • v.17 no.2
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    • pp.87-92
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    • 1994
  • A series of $7-{2-(aminothiazol-4-yl)-2-Z-({\gamma}-lacton-3-yl)oxyiminoactamido}$ cephalosporins with various substituents at the 30position in cephem nucleus in cephem nucleus were synthesized and evaluated microbiologically. The tested compounds showed potent activities but were somewhat less active than cefotaxime or cefixime against a wide variety of Gram-positive and Gram-negative bacteria.

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Rh2(Opiv)4-Catalyzed Reactions of Diazo Compound Derived from Meldrum's Acid and Styrenes. Efficient Synthesis of Cyclopropanes

  • Lee, Yong-Rok;Choi, Jung-Hyun
    • Bulletin of the Korean Chemical Society
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    • v.27 no.4
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    • pp.503-507
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    • 2006
  • The rhodium(II)-catalyzed reactions of diazo compound derived from Meldrum's acid with a variety of styrenes have been examined. These reactions provide a rapid route to the preparation of cyclopropanes with a variety of substituents on the benzene ring. The mechanistic pathway for the formation of these products has been also described in terms of a stepwise mechanism.