• Journal of Korean Neurosurgical Society
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• 제29권8호
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• pp.1024-1029
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• 2000

Objectives : With recent improvements in neuroimaging and the development of third and fourth-generation radiosurgical dose-planning soft ware, came a renewed interest in using radiosurgery for the treatment of movement disorders. Radiosurgery involves no opening of the cranium and no incisions, eliminating both the risk of hemorrhage from passing an electrode to the depths of meningitis from operative infection. It is for these reasons stereotactic radiosurgical treatment of movement disorders has value in a small subgroup of patients. The authors report four cases of Parkinson's disease and one case of dystonia that were treated by Gamma knife. Methods : Radiosurgical nucleus ventralis intermedius thalamotomy using the gamma knife unit was performed to make lesion in two Parkinson's disease patients. A radiation dose of 120Gy was delivered to nucleus using a single 4-mm collimator plug pattern following classic anatomical landmarks. Patients were followed for a median of 10.5 months(range 9-12 months). An independent neurological evaluation of tremor, based on the change in the United Parkinson's Disease Rating Scale tremor score(UPDRS), was correlated with a subjective evaluation. Gamma knife ventrolateral(V.O.P) thalamotomy was performed in one case of dystonia. A central dose of 150Gy was delivered and the patient was followed for 18 months. Gamma knife globus pallidus interna pallidotomy was performed in two Parkinson's disease patients. A radiation dose of 130Gy(range 120-140Gy) was delivered. Patients were followed for a median of 13 months(range 9-14 months). Result : Ventrolateral thalamotomy in dystonia produced regained left hand usage in order to be able to use the telephone. Ventralis intermedius thalamotomy produced an excellent improvement of the tremor in one case, mild improvement of the tremor in the other case of Parkinson's disease. A globus pallidus internalis(GPi) pallidotomy produced improvement of rigidity and dyskinesia : one other showed no change. There were no neurological complications. Conclusion : Gamma Knife thalamotomy considered a safe and effective technique for the treatment of tremor in Parkinson's disease. Although the results from Longer follow-up is not available yet, the short-term results seem to be encouraging.

• 인지과학
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• 제28권4호
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• pp.245-265
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• 2017

최근 인지적 통제에 대한 연구들은 최적의 통제 수준이 보상과 비용에 의해 결정된다는 것을 밝혀냈다. 보상이 가지는 가치는 주관적이며 이에 따라 최적의 신호 강도도 달라진다. 우리는 인지적 통제에 대한 노화의 영향에 대한 연구 결과들이 비일관적인 이유가 노인이 탄력적으로 통제 신호를 조절한 결과일 수 있다고 보았다. 다시 말해, 노인은 최적의 통제 수준을 결정하는 능력을 잘 유지하고 있을 수 있는데, 이는 전대상회의 역할로 알려져 있다. 반면 인지적 통제에서 노화에 따른 기능의 감퇴는 주로 규칙 표상의 유지와 억제에서 나타나는데, 이는 주로 외측전전두피질이 담당하고 있다. 본 연구는 청년과 노인에게 보상의 유형을 조절한 Go-Nogo 과제를 수행하게 하여 각 보상 조건에서 행동결과와 ERN(Error-Related Negativity) 크기를 비교하였다. 두 집단 모두는 각 연령에게 가장 중요하다고 여겨지는 조건에서 가장 뛰어난 행동 수행과 가장 큰 ERN 크기를 나타내었다. 또한 노인은 d'과 정확률에서는 연령차를 나타내었으나 ERN의 크기에서는 연령차를 나타내지 않았다. 이와 같은 결과는 인지적 통제의 각 과정에 대한 노화의 영향이 상이할 수 있을 가능성을 보여준다.

• 감성과학
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• 제13권2호
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• pp.327-336
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• 2010

본 연구에서는 텐셀 자카드 직물에 은행나무 추출물(ginkgo biloba extract)과 실리콘 유연제(silicon softener)를 처리 할 때 실리콘유연제를 동시에 처리하는 방법과 은행나무추출액 처리하고 난 후에 다른 bath에서 실리콘유연제를 연속적으로 처리하는 방법 중 어느 것이 더 촉감이나 선호도에 더 영향을 주는지를 찾아내고자 하였다. 따라서 텐셀 자카드 직물에 은행나무추출액과 실리콘유연제를 처리하여 KES-FB system을 통하여 역학적 특성 및 객관적 태의 변화를 살펴보고, 침장용 직물이 가지는 개별 감각 및 종합 감각의 주관적 감성을 평가하였다. 이밖에도 침장용 직물에서 중요하게 여겨지는 소비자의 개별감각 요소를 평가하여 침장용 직물개발의 기초자료를 마련하고자 하였다. 텐셀 자카드 직물에 은행나무추출액과 실리콘유연제를 처리하게 되면 인장특성인 EM, WT, RT는 증가하여 신축성이 있고 형태안정성이 좋아지며, 인장특성 전단특성이 감소하여 유연성이 증가하고, 무게와 두께가 증가로 부피감이 커져, THV는 증가하였다. 주관적 감성 평가 결과 개별감각 중 부드러움, 따뜻함, 탄력감, 부피감은 증가하고 거침은 감소하는 것으로 평가하였다. 또한 부드러움, 부피감, 따듯함을 침장용 직물이 갖는 중요한 개별감각 요소로 평가하였다. 은행나무추출액과 실리콘유연제를 처리할 경우 촉감이 좋아지고 선호도가 높아지는 것으로 평가되었다.

• 한국산학기술학회논문지
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• 제19권8호
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• pp.78-85
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• 2018

본 연구에서는 2017년 20건의 화재가 발생한 냉동창고 화재사례중 발화원인의 판정에 다수의 의견이 존재하였던 사례에 대해 연구하였다. 연구 방법론은 NFPA 921 CODE에서 규정하고 있는 과학적 화재조사 방법이다. 과학적 화재조사 방법은 가설설정을 통한 논리적 추론에 의한 화재조사 방법으로 발화원인 판단에 오류를 최소화 시킨다. 반면에 비과학적 화재조사 방법은 발화원인의 판단에 주관적 추측, 추론적 판단 등의 비합리적 요소의 개입으로 많은 오류를 발생시킨다. 이는 결국 인적, 물적 책임의 문제 및 학문적 퇴보를 가져온다. 특히 목격된 화재(Sighted fire)에 비해 목격되지 않는 화재(Fire not seen)의 경우 원인조사에 있어서 더 많은 발화원인 의 오류를 만든다. 본 연구에서는 2017년 **시 **마트에서 발생한 냉동창고 정온전선의 화재사례에 대해 화재조사 보고서의 검토, 현장조사를 바탕으로한 가설A 와 가설B의 설정하였다. 설정된 가설은 NFPA 921 code 규정하고 있는 연역적 검정 방법중 실험으로 검정하였다. 이러한 분석방법은 향후 목격되지 않는 화재(Fire not seen) 및 원인 불명 화재의 발화원인 판단에 NEW Paradigm의 구축 할 것이다. 또한 본 연구의 실험 자료는 냉동창고 제조사 및 운영사에 통보, 화재 예방을 위한 기초 자료로 활용 될 것이다.

• 한국도서관정보학회지
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• 제8권
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• pp.127-154
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• 1981

Today's complicated society with a rapid change needs more objective and accurate data for the better managerical decisions and the prospect for the future other than the intuition or subjective experience by men themselves. These data can't be extracted without the analysis of actual data by a n.0, pplying any of mathematical techniques. One of these mathematical techniques, called bibliometrics has been newly developed in the field of library and information science to extract the objective data for the better services through the library operations. The Beadford's Law, one important law in bibliometrics has provided rather scientific and objective basis on the more valid building of library collection within the constraints of budget. The purpose of the study is to investigate the theory of the Bradford's Law, to clarify the possible areas of its a n.0, pplication, and to discern some problems in doing so. The results of the study can be summarized as follows; (1) There is certain difference between the graphical formulation and verbal formulation of Bradford's Law. But this law is very useful for the field of library and information science, owing to the flexibility of the a n.0, pplication of the law in the field. (2) The minimal nucleus can consist of a single periodical only if j, the number of relevant papers in the most productive journals is greater than Z/2. On the other hand, if j is less than or equal to Z/2, then the minimal nucleus will consist of 2 or more periodicals. (3) It is possible to design the most compact selection of scientific periodicals covering any specified percentage P among the total periodicals by using the formulation, log n=Plog N+(1-P)logs, or Nlog N/s=P center dot N log N/s. (4) If there is need to provide all the articles needed by users the given budget, the library can purchase the proper number of journals, by using the formulation, f center dot AN=An+PN (log N/s-logn/s). (5) In the building of the library collection based on the decreasing ratio of use, the library can subscribe to the proper number of journals according to the satisfactory degree of the need, by using the formulation, f=Nu+uNlogN/S-uNlogn/s / nNlogN/s = 1+logN/m /logN/s (6) If the order of valuable journals is decided according to the frequency of being cited, the order can't always represent the value. (7) The evaluation criteria for the journals with high value, but less cited should be made a further study.

• 한국과학교육학회지
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• 제37권3호
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• pp.407-416
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• 2017

이 연구에서는 협력적 비유 생성 활동에서 나타나는 비유의 변화과정과 소집단 및 전체 학급 토론의 특징을 분석하였다. 서울특별시에 소재한 고등학교에 재학 중인 24명의 학생을 대상으로 협력적 비유 생성 활동을 적용한 수업을 진행하였다. 학생들이 생성한 개인 비유와 소집단 비유, 수정된 소집단 비유를 비교하여 비유의 변화과정을 분석하였으며, 비유 생성 활동을 위한 소집단 토론과 전체 학급 토론의 특징을 분석하였다. 연구 결과, 비유의 변화 과정은 공유속성이 추가되는 경우, 비공유 속성을 인식하는 경우, 대응 오류가 수정되는 경우의 세 가지 변화 유형이 나타났다. 학생들은 여러 개인 비유 중 하나를 선택하는 방식으로 소집단 비유를 생성하였고, 이때 비유의 설명력, 독창성, 친숙도 등을 고려하는 것으로 나타났다. 학생들은 비유 생성 활동을 주관적이고 창의적인 활동이라고 인식하여 비유 생성 활동에 대한 정서적 부담감이 적었고 소집단 토론에서 갈등의 요소도 적었다. 전체 학급 토론에서는 다양한 비유가 제시되었으며 전체 학급 토론의 경쟁적인 분위기는 학생들이 비유가 갖는 비공유 속성에 주목하게 하였다. 소집단 비유 수정 단계에서 학생들은 비공유 속성을 비유가 갖는 제한점으로 추가하거나 비공유 속성을 갖지 않도록 비유를 변형하는 방식으로 비유를 수정하였고, 새로운 비유를 생성하는 경우는 거의 없었다. 이상의 결과를 바탕으로 협력적 비유 생성 활동을 적용한 수업을 효과적으로 진행하기 위한 방안을 논의하였다.

• 대한한방체열의학회지
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• 제1권1호
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• pp.38-46
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• 2002

1. Objectives Among many symptoms that the climacteric patients complain of, the major subjective symptom is both heat in the upper part and cold in the lower part of the body(e.g foot, knee, and leg). We use DITI as a method to prove the symptoms of climacteric patients such as both heat in the upper part and cold in the lower part of the body, diagnose these symptoms, and follow up the progress of the clinical treatments. 2. Subjects and Methods We compare the subcutaneous heat of the climacteric patients with the symptom of heat in the upper part and cold in the lower part of the body with young women without any specific disease. The age distribution of the experimental group is 28 patients in 40's, and 22 in 50's. The mean age of the experimental group is $48.5{\pm}4.25$. The age distribution of the control group is 17 patients in teen, 26 in 20's, 7 in 30's. The mean age of the control group is $23.31{\pm}6.45$. We measure the subcutaneous heat on the cheeks, upper arms, palms, thighs, knees, dorsum pedis, lower back, hip, upper abdomen, lower abdomen of both groups and analyse the results. 3. Statistical methods All the results are statiscally analysed using student T-test of Microsoft Exel program. Statistically significant value by the analysis of variance procedure is P<0.05. 4. Results 1. The subcutaneous heat of the whole body of the experimental group shows hypothermia compared with control group, and the hypothermic pattern gets severe on the periphery. ${\Delta}T$ between the right and left side of the body in experimental group is larger than that of control group. 2. ${\Delta}T$ between the cheeks and the hypogastric in the experimental group is significantly larger than that of the control group, which shows cold face. 3. ${\Delta}T$ between the upper arms and the palms in the experimental group is significantly larger than that of the control group, which shows cold hand. 4. ${\Delta}T$ between the thighs and the knees in the experimental group is significantly larger than that of the control group, which shows cold knee. 5. ${\Delta}T$ between the thighs and the feet in the experimental group is significantly larger than that of the control group, which shows cold foot. 6. ${\Delta}T$ between the hip and the lower back in the experimental group is significantly larger than that of the control group. That shows the Lower back is warmer than the hip. 7. ${\Delta}T$ between the upper and the lower abdomen in the experimental group is significantly larger than that of the control group, which shows cold hypogastric.

• 재활치료과학
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• 제1권2호
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• pp.41-53
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• 2012

목적 : 본 연구는 한국 작업치료사들의 근거기반 치료(Evidence-Based Practice; EBP)에 대한 인식도, 임상적 의사결정에 사용하는 근거자원, EBP 실행을 방해하는 요인을 조사하고자 하였다. 연구방법 : 2009년 12월부터 3월까지 임상에 있는 작업치료사들에게 총 500부를 배부하였고, 그 중 회수된 160부(32%)를 기술통계를 통해 분석하였다. 결과 : 설문의 응답자는 남성보다 여성이 많았고, 치료경력이 5년 미만인 치료사가 전체의 90% 이상을 차지하였다. 응답자의 대부분은 EBP와 관련된 교육 경험이 없고(76%), 현재 실시하지 않는 것(55%)으로 나타났다. 또한 치료 시 활용하는 근거자원도 주관적인 판단이었다. 그러나 인식도 조사에서 EBP를 통해 작업치료사의 전문성이 향상될 수 있고(96%), 임상적인 판단에 도움을 준다고(88%) 응답하였다. 치료사의 대부분은 EBP 적용을 위해 도움을 줄 수 있는 개선책으로 근거자원 탐색을 위한 시간적인 여유 확보(90%)와 교육과정 참여가 필요(92%)였다. 이와 같은 결과는 임상 현장에서 EBP에 대한 적용 정도는 낮으나 인식도는 높은 것을 보여주어 향후 EBP에 대한 교육프로그램 활성화의 필요성을 간접적으로 제시하였다. 결론 : 한국 작업치료가 질 좋은 서비스를 제공하기 위해 적극적인 교육과정 개설과 강사 개발이 필요하고, 전국 대학의 작업치료전공 학생들이 근거기반의 교육을 받을 수 있도록 힘써야 할 것이다. 또한 작업치료사의 전문성을 향상시키기 위한 EBP가 조속히 이루어져 하고, 그에 교육프로그램과 그 효과성에 대한 연구가 끊임없이 이루어져야 할 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권8호
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• pp.3645-3651
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• 2012

Conventional pap smear (CPS) examination has been the mainstay for early detection of cervical cancer. However, its widespread use has not been possible due to the inherent limitations, like presence of obscuring blood and inflammation, reducing its sensitivity considerably. Automated methods in use in developed countries may not be affordable in the developing countries due to paucity of resources. On the other hand, manual liquid based cytology (MLBC) is a technique that is cost effective and improves detection of precursor lesions and specimen adequacy. Therefore the aim of the study was to compare the utility of MLBC with that of CPS in cervical cancer screening. A prospective study of 100 cases through MLBC and CPS was conducted from October 2009 to July 2010, in a Medical College in India, by two independent pathologists and correlated with histopathology (22 cases). Morphological features as seen through MLBC and CPS were compared. Subsequently, all the cases were grouped based on cytological diagnosis according to two methods into 10 groups and a subjective comparison was made. In order to compare the validity of MLBC with CPS in case of major diagnoses, sensitivity and specificity of the two methods were estimated considering histological examination as the gold standard. Increased detection rate with MLBC was 150%. The concordance rate by LBC/histopathology v/s CPS/histopathology was also improved (86% vs 77%) The percentage agreement by the two methods was 68%. MLBC was more sensitive in diagnosis of LSIL and more specific in the diagnosis of inflammation. Thus, MLBC was found to be better than CPS in diagnosis of precursor lesions. It provided better morphology with increased detection of abnormalities and preservation of specimen for cell block and ancillary studies like immunocytochemistry and HPV detection. Therefore, it can be used as alternative strategy for cervical cancer prevention in limited resource settings.

• 한국보건간호학회지
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• 제18권2호
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• pp.312-329
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• 2004

This study was examined 718 workers who had consistent blood pressure results in 2001 and 2002 general health examinations that were held at a work places managed by a health care agency in Seoul. Significant results are found as follows by analysing SPSS 11.0 on the result of self-recorded questionnaires investigated from Mar 1, 2003 to April 30, 2003. 1. A sampled healthy group and a sampled unhealthy group had significant differences in four variables out of possible nineteens that are sex, age, marriage and occupation. The unhealthy group had more males than females, more aged (over 50 years old) than youngers (under 50 years old), more married than singles, more manufacturing workers than non-manufacturing workers. In the case of systolic blood pressure, as the healthy group had 16.52mmHg while that of the other group had 149. 58mmHg, 33.06mmHg of difference between those groups were detected. In the case of diastolic blood pressure, 74.93mmHg of the healthy group and 96.53mmHg of the unhealthy group yielded 21.60mmHg of difference between them. This result implies that a guidance of health care is required to be aware of 20-30mmHg volatility in blood pressure rate or to understand and treat properly own blood pressure. as it is difficult to detect hypertension in early stage due to no initial symptom. According to the result. an establishment of management system of workers, companies and health care agencies is required for consist health care. 2. In terms of risky habits to health, the unhealthy group had more proportion of past smokers, over-twice-a-week drinkers, people with higher obesity rate. However, in terms of excercise, the proportion of regularly exercising people is higher in the unhealthy group while that of non-exercising people is higher in the healthy group. On the other hand. the average grade of health practicing behaviour in two groups are not significantly different as the health group had 3.00 out of possible 6.00 while the other had 3.10. This result means that as workers are not interested in health practicing behaviour. health promoting programmes must be developed in such a way of various method of motivations and incentives. Particularly this implies that distortional objectives of exercises should be readjusted through health guidance. 3. Systolic blood pressure in the healthy group can be explained by sex and the obesity rate while that in the unhealthy group can be explained by subjective health awareness and the obesity. Diastolic blood pressure in the healthy group can be explained by sex and the obesity rate like the former. The obesity rate was significant variable affecting the blood pressure of both groups, and particularly the effect to the unhealthy group was remarkably higher than that to the healthy group. Therefore, this research identified that the health care on the blood pressure of workers is not only limited to hypertension patients, but also extended to all workers. In order for consistent care, an establishment of management system of workers, companies and health care agencies is required.