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Development and Validation of Reference Material for Proficiency Testing of Blood Heavy Metals in Environmental Biomonitoring (환경 바이오모니터링에서의 혈중 중금속 분석 숙련도 시험을 위한 표준물질 제조 및 적용성 평가)

  • Im, Hosub;Yang, Minho;Oh, Selim;Kim, Soyoung;Jung, Hojun;Cho, Yong Min;Lee, Jung Sub;Kim, Hyun Jeong;Lee, Chae Kwan;Moon, Chan-Seok;Lee, Jong-Wha
    • Journal of Environmental Health Sciences
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    • v.42 no.6
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    • pp.450-464
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    • 2016
  • Objectives: This study developed and validated reference materials (RMs) to analyze metal compounds in blood. Methods: We referred to KoNEHS (Korea National Environmental Health Survey) to estimate concentrations of blood metals (cadmium, Cd; lead, Pb; mercury, Hg) and applied analytical methods (inductively coupled plasma - mass spectroscopy, ICP-MS, for Cd and Pb; graphite furnace - atomic absorption spectrometry, GF-AAS, for Cd and Pb; and direct mercury analyzer, DMA, for Hg). Homogeneity and stability tests were carried out. In addition, certified values and uncertainties of RMs were calculated through internal and external experiments. All RMs were developed and assessed in various forms according to element, analytical method, and two types of concentration levels high concentration for occupational exposure and low concentration for environmental exposure. Results: All samples showed acceptable homogeneity, except for low concentration of Cd in the GF-AAS method. Short- and long-term stabilities were satisfied by ANOVA testing. In the inter-laboratory comparison, robust medians were lower than the certified values of all RMs (robust median/reference value; $1.301/1.327{\mu}g/L$ for Cd, ICP-MS, low concentration; $3.152/3.388{\mu}g/L$ for Cd, ICP-MS, high concentration; $1.219/1.301{\mu}g/L$ for Cd, GF-AAS, low concentration; $3.074/3.321{\mu}g/L$ for Cd, GF-AAS, high concentration; $14.473/14.516{\mu}g/L$ for Pb, ICP-MS, low concentration; $50.069/50.114{\mu}g/L$ for Pb, ICP-MS, high concentration; $12.881/14.147{\mu}g/L$ for Pb, GF-AAS, low concentration; $47.015/47.591{\mu}g/L$ for Pb, GF-AAS, high concentration; $4.059/4.218{\mu}g/L$ for Hg, DMA, low concentration; $11.474/11.181{\mu}g/L$ for Hg, DMA, high concentration). Conclusion: This study demonstrates procedures for developing and validating RMs for biomonitoring in the field of the environmental health.

A Study on Speedy Water Content Measurement Method for Soils (흙의 급속 함수비 측정방법에 관한 연구)

  • Park, Sung-Sik;Kim, Ju-Young;Lee, Sae-Byeok
    • Journal of the Korean Geotechnical Society
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    • v.33 no.1
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    • pp.57-65
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    • 2017
  • During a construction of embankment, sub base, or retaining wall backfill, the speedy measurement of water content is necessary. In this study, a test method for field determination of water content of soil by the calcium carbide gas pressure (speedy water content measurement method) was evaluated for its reliability and accuracy. Dry oven and microwave oven methods were also used for water content measurement. In the test, weathered granite and Nakdong River sand in the site and kaolinite were used for water content measurement. The mass of 20, 22, 24, 26, 28, and 30 g of soil was respectively tested for 1, 3, and 5 min. The effect of each sample on water content was compared one another and analyzed. As the mass and testing time increased, the water content increased. The amount of soil was more important factor than testing time for the speedy water content measurement. In order to obtain similar result to that of dry oven method, 3 min of testing time with 24 g of soil was necessary for weathered granite classified as SM and 3 min with 30 g for Nakdong River sand classified as SP. For Nakdong River sand with 20-50% of kaolinite, the water content by speedy measurement increased as the clay content increased.

Field Application on Mass Concrete of Combined Coarse Particle Cement and Fly-Ash in Mat Foundation (조분(粗粉) 시멘트와 플라이애시를 복합 치환한 매트 기초 매스콘크리트의 현장적용)

  • Han, Cheon-Goo;Jang, Duk-Bae;Lee, Chung-Sub
    • Journal of the Korea Institute of Building Construction
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    • v.10 no.4
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    • pp.11-20
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    • 2010
  • This study carried out a Mock-up test to apply Low-heat Cement (CF) that is adjusted to a fineness of $3,000\;{\pm}\;200\;cm^2/g$ by substituting Coarse particle Cement (CC) and fly ash with ordinary Portland Cement (OPC), then applied it on-site. The result of the test is as follows. The Mock-up test showed that the amount of admixture in CF increased SP agent and AE agent slightly more compared to OPC, while temperature history showed that the highest temperature of CF was around $6{\sim}10^{\circ}C$ lower than that of OPC. Compressive strength in CF was low compared to that of OPC, but the strength width became narrow at the age of 28 days, which is not considered to be significant. In on-site application, slump, air content and chloride content all satisfied the target values, while the temperature history showed that the highest temperature in the center by each cast was about $34^{\circ}C$ in the first cast, $42^{\circ}C$ in the second cast, and $39^{\circ}C$ in the third cast. Compressive strength of specimen for strut management showed low value compared to standard curing, but its strength was reduced at the age of 28 days.

Enhancing the Stability of Slopes Located below Roads, Based on the Case of Collapse at the Buk-sil Site, Jeongseon Area, Gangwon Province (강원도 정선지역 북실지구 깎기비탈면 붕괴 사례를 통한 도로 하부 비탈면 안정성 확보에 관한 고찰)

  • Kim, Hong-Gyun;Bae, Sang-Woo;Kim, Seung-Hyun;Koo, Ho-Bon
    • The Journal of Engineering Geology
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    • v.22 no.1
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    • pp.83-94
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    • 2012
  • Slopes are commonly formed both above and below roads located in mountainous terrain and along riversides. The Buk-sil site, a cut slope formed below the road, collapsed in October, 2010. A field investigation determined the causes of failure as improper drainage of valley water from the slope above the road and direct seepage of road-surface water. These factors may have accelerated the collapse via complex interaction between water and sub-surface structures such as bedding. Projection analysis of the site showed the possible involvement of plane, wedge, and toppling failure. Safety factors calculated by Limit Equilibrium Analysis for plane and wedge failure were below the standard for wet conditions. The wetness index, analyzed using topographic factors of the study area, was 9.0-10.5, which is high compared with the values calculated for nearby areas. This finding indicates a high concentration of water flow. We consider that water-flow control on the upper road is crucial for enhancing slope stability at the Buk-sil site.

Hibiscus syriacus 'Dasom', A New Flower-Color Mutant Variety Developed by Radiation Breeding (방사선 육종에 의한 화색변이 무궁화 신품종 '다솜' 육성)

  • Kim, Sang Hoon;Kim, Dong Sub;Kim, Jin-Baek;Ha, Bo-Keun;Lee, Duk Man;Song, Hi Sup;Kang, Si-Yong
    • Horticultural Science & Technology
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    • v.33 no.2
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    • pp.298-301
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    • 2015
  • A new Hibiscus syriacus variety, 'Dasom', was developed by radiation breeding using gamma ray exposure at the Korea Atomic Energy Research Institute (KAERI). Seeds of the original variety, 'Hongsun', were collected in 1993. These seeds were irradiated at 100 Gy dose and $M_1$ seeds were planted in a field of the KAERI in 1994. Lines with preferred flower color that were going to be used for street trees were initially selected in 1998. Analyses of characteristics were conducted from 2005 to 2010. The 5-year-old 'Dasom' plants were approximately 106 cm in height and averaged 19 branches, and thus were suitable for street trees. The flowers of 'Dasom' were semi-double type with medium red color and red eye spots. Petal length and width were about 4.0 cm and 3.3 cm, respectively. Flower diameter was slightly small, at about 5.8 cm, because of highly overlapping petals. The flowering period of 'Dasom' was about 105 days, which was 6 days shorter than that of the original variety, 'Hongsun'. However, the main charactersistics of 'Dasom' including leaf shape were similar to those of the original variety, 'Hongsun'.

Development of Differential Diagnosis Scale Items for Adductor Spasmodic Dysphonia and Evaluation of Clinical Availability (내전형 연축성 발성장애 감별진단 문항 개발과 임상적 유용성 평가)

  • Cho, Jae Kyung;Choi, Seong Hee;Lee, Sang Hyuk;Jin, Sung Min
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.30 no.2
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    • pp.112-117
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    • 2019
  • Background and Objectives The purpose of this study was to develop the differential diagnosis scale containing items from adductor spasmodic dysphonia (ADSD) to muscle tension dysphonia (MTD) and the determine clinical utility of newly developed items. Materials and Method The four parts of pitch, redirected phonation, automatic speech and voiced sound were selected for analyzing the characteristics of ADSD in the literature. One part of tense voiceless sound was developed according to the Korean manner of articulation. The content validity was evaluated based on 5 scales (1-5 point) analysis from 30 experts. One hundred patients (50 ADSD and 50 MTD) were recorded in reading a sentence and sustained phonation. The two speech language pathologist evaluated recorded voices through a blind test using 4 scales (0-3 point) for newly developed items. Results As a result of verifying the content validity of items with experts, it was identified that the differentiated items were valid with 4.2 out of 5. Through the differential diagnosis between two groups according to the items, the correlation between sub-domains and total scores was shown as higher than 0.710. The result of analyzing the reliability on each diagnosis domain was 0.840-0.893, which showed the internal consistency of items was great. Newly developed five parts of ADSD were significantly higher than those of MTD with strong correlation (p<0.01). The reliability among the evaluators was analyzed as high with 0.892. Conclusion In this study, the differential diagnosis scale of ADSD was revealed as having validity and reliability. It is considered that it will be useful for differentiating ADSD and MTD in the clinical field.

Comparative Assessment of Good Agricultural Practices Standards in Agricultural Product Quality Control Act with respect to Produce Safety Rule in Food Safety Modernization Act (식품안전현대화법의 농산물안전규칙과 농산물품질관리법의 농산물우수관리기준 비교평가)

  • Yoon, Deok-Hoon
    • Journal of Food Hygiene and Safety
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    • v.33 no.1
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    • pp.12-22
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    • 2018
  • The US government has enacted the Food Safety Modernization Act (FSMA) in 2011, which is being phased in and planned. The final Rules of Produce Safety focus on biological hazards related to agricultural production, harvesting, packaging and storage, which are being phased in since 2017 depending on farm scale. As a result of comparison with the Korean-GAP (Good Agricultural Practices) standards, it is difficult to compare the two standards to be compared with each other by 1:1. However, many of the Korean-GAP standards are similar to FSMA Produce Safety rules. However, the Korean-GAP standards can be judged differently according to the evaluator as a comprehensive standard, so the details of the standards need to be reinforced. In terms of the provisions, the Korean-GAP standards are the most appropriate for the safety of workers (FSMA Subpart D), followed by livestock and wild animals (FSMA Subpart I), buildings, equipment and tools (FSMA Subpart L) and harvesting activities (FSMA Sub-part K). However, there are some weaknesses in the field of agricultural water management (FSMA Subpart E) and farm manager's qualifications and training (FSMA Subpart C), and the response to the biological soil amendments of animal origin and human waste (FSMA Subpart F) is weak. The FSMA regulation is not a certification standard, but it is expected that the marbling effect, which is the standard laid down by the United States leading the world food safety standards, is expected to be considerable. Therefore, we hope that the review of the Korean-GAP standards will help improve the quality of agricultural products and expand our exports, since the standard for responding to microbiological safety emphasized in the FSMA regulations is the Korean-GAP standard.

Change in Weed Flora with Season and Cultivated Crop and Land (계절별(季節別), 재배작물(栽培作物) 및 경작지별(耕作地別) 잡초식생변화(雜草植生變化))

  • Ryang, H.S.;Chun, J.C.;Hwang, I.T.
    • Korean Journal of Weed Science
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    • v.4 no.1
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    • pp.4-10
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    • 1984
  • This experiment was conducted to determine the change in weed flora with season and cultivated crop and land. There are 44 species in 38 genera and 18 families, consisting of 22 annual, 11 biennial and 9 perennial weeds in uplands in Jeonbug Province. Digitaria sanguinalis Scopol. occurred with the highest frequency of 67.2% and in decreasing order Portulaca oleracea L., Chenopodium album L. and Erigeron canadensis L. followed. About 60% of total sites studied indicated Simpson`s index ranging from 0.20 to 0.50. The Simpson`s index decreased from 0.65 on June 8 to 0.15 on November 10. Dominant weed species were Alopecurus aequalis Sosbol, and Polygonum hydropiper Spach in double cropping paddy field, but D. sanguinalis and P. oleracea were the dominant species in uplands. In reclaimed uplands various weed species including, 4rtemisia asiatica Nakai occurred almost equally. Average Simpson`s index for six crops studied was 0.40 and irrespective of the crops being cultivated P. oleracea and D. sanguinalis were dominant weed species and Y. hydropiper, C. album, Exolus blitum Grenier and E. canadensis were sub-dominant.

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The United States CHES Program: The Role and Development of the Modern Health Educator (미국의 CHES 프로그램: 현대 보건교육사의 역할과 제도의 발전)

  • Sohn, Ae-Ree;Burzo, Jamie
    • Korean Journal of Health Education and Promotion
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    • v.27 no.5
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    • pp.63-71
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    • 2010
  • Objectives: The field of health education is still relatively new and is therefore evolving and developing rapidly throughout the world. Many countries' certification programs are still being created. This paper will discuss on the US CHES system of regulation, accreditation, and implementation for the future development of international health education programs. Methods: This article focuses on the United States CHES credentialing program, specifically on its historical development and the roles, employment settings and socioeconomic demographics of current CHES professionals through literature review. Results: The roles and skills required vary by employment setting, with seven universally recognized responsibilities of health educators. There are also 35 key competencies which are crucial to the role of the health educator, with 163 sub-competencies performed by all health educators. The employment of health educators will increase from 62,000 in 2006 to 78,000 in 2016. As the costs of healthcare increase, employers are projected to hire more health educators to decrease healthcare costs through prevention and early detection of chronic illnesses. Community health non-profit agencies, academia, healthcare (hospital/clinic), schools, government/government contracting, and businesses are some of the most widespread employment settings for health educators in the United States. Conclusion: Better understanding of this longstanding and successful program will benefit countries developing their own certification system. The variety and specificity of the information on the US CHES program may be of value as South Korea continues to develop its Korean CHES program.

A Study of the Development of a Korea Wind Chill Temperature Index (I) - Focusing on the Distribution of Existing Wind Chill Temperature Index and Sensitivity Analysis of Model - (한국형 체감온도지수 개발연구(I) -기존 체감온도지수 분포 및 민감도 분석 -)

  • Park, Jong-Kil;Jung, Woo-Sik;Kim, Eun-Byul;Park, Gil-Un
    • Journal of the Korean earth science society
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    • v.28 no.7
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    • pp.878-890
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    • 2007
  • This study aimed to provide a fundamental basis for the development and promotion of a Korea windchill temperature index model in the field of human biometeorology. For this, a sensitivity model currently being used by KMA (Korea Meteorological Administration) was analyzed. The results of the analysis showed that the Korean peninsula could be divided into the urban area, the coastal/island area, the inland area, and the mountain area. The average temperature was highest in the coastal/island area, while it was lowest in the mountain regions. The lowest temperature in the urban and coastal/island areas was 20 degrees below zero and that in the inland and mountain regions were 30 degrees below zero. As for wind speed, both average and maximum wind speed were highest in the coastal/island area. The distribution of temperature and wind speed in winter was similar to that of the entire period. The results of the JAG/Tl and Missenard model sensitivity showed that temperature tends to have more influence on sensitivity than any other factors. In sub-zero temperature, however, the influence of wind speed tends to increase.