• 한국항공우주학회지
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• 제31권1호
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• pp.1-7
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• 2003

익형에 대한 공력 최적설계 프로그램을 개발하였으며, 점성 유동장에 대한 보다 정확한 정보를 설계에 반영하기 위하여 나비어-스톡스 방정식을 사용하였다. 최적설계 방법으로는 민감도 해석을 위하여 수정유용방향탐색방법(Modified Method of Feasible Directions, MMFD)을 사용하였으며 이동거리 계산을 위하여 다항식 보간법을 사용하였다. 또한 설계시간을 단축하기 위하여 MPI를 사용하여 병렬화하였다. 전체 유동장을 8개의 영역으로 분할하였으며 분할된 영역은 지정된 프로세서에 할당하여 계산을 수행하였다. 민감도 계산을 위하여 각 프로세서에 할당하여 계산을 수행하였다. 민감도 계산을 위하여 각 프로세서에 각 탐색방향을 할당하여 민감도를 병렬계산하였다. 본 연구의 수행 결과 양력은 허용한도 내의 일정한 값을 유지하는 가운데 항력이 감소된 최적화된 익형의 형상을 설계할 수 있었다.

• 한국해안해양공학회지
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• 제17권3호
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• pp.138-148
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• 2005

부유체 및 부유식 교량과 같은 부유식 구조물이 파랑하중에 대하여 나타내는 동적거동을 주파수영역에서 구하는 연구를 수행하였다. 먼저, 부분적으로 유체에 잠겨 파랑하중의 작용을 받는 부유체에 대하여, 이의 강체운동과 관련된 동유체력계수인 부가질량, 감쇠 및 파강제력를 선형포텐셜이론과 경계요소법을 이용하여 주파수 영역에서 산정한다 다음으로,부유식 교량과 같이 앞에서 구한 부유체로 지지되며 유한요소를 이용하여 모델링 되는 부유식 구조물에 대하여, o)의 동적거동에 관한 운동방정식을 수립한다. 동유체력계수들이 주파수 의존적 성질을 가지므로 해석은 주파수영역에서 수행한다. 적용 예제로서 반구와 같은 부유체를 이용하여 해석결과를 문헌과 비교 검증한 후,부유식 교량을 지지하는 폰툰형 부유체에 대한 동유체력계수들을 구하고, 이를 이용하여 설계 파랑하중을 받는 부유식 교량의 동적 거동해석을 수행한다. 해석 예제를 주파수영역에서 해석한 결과 입사파스펙트림의 피크 주파수와 교량의 고유진동수가 가까워 응답이 증폭될 소지가 있었으나 주파수 의존적인 파강제력의 피크가 벗어난 영향으로 응답이 증폭되지 않음을 알 수 있다.

• Asian-Australasian Journal of Animal Sciences
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• 제30권8호
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• pp.1183-1189
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• 2017

Objective: Owing to the public availability of complete genome sequences, including avian species, massive bioinformatics analyses may be conducted for computational gene prediction and the identification of gene regulatory networks through various informatics tools. However, to evaluate the biofunctional activity of a predicted target gene, in vivo and in vitro functional genomic analyses should be a prerequisite. Methods: Due to a lack of quail genomic sequence information, we first identified the partial genomic structure and sequences of the quail SH3 domain containing ring finger 2 (SH3RF2) gene. Subsequently, SH3RF2 was knocked out using clustered regularly interspaced short palindromic repeat/Cas9 technology and single cell-derived SH3RF2 mutant sublines were established to study the biofunctional activity of SH3RF2 in quail myoblast (QM7) cells during muscle differentiation. Results: Through a T7 endonuclease I assay and genotyping analysis, we established an SH3RF2 knockout (KO) QM7#4 subline with 61 and 155 nucleotide deletion mutations in SH3RF2. After the induction of myotube differentiation, the expression profiles were analyzed and compared between regular QM7 and SH3RF2 KO QM7#4 cells by global RNA sequencing and bioinformatics analysis. Conclusion: We did not detect any statistically significant role of SH3RF2 during myotube differentiation in QM7 myoblast cells. However, additional experiments are necessary to examine the biofunctional activity of SH3RF2 in cell proliferation and muscle growth.

• 한국수학교육학회지시리즈A:수학교육
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• 제57권2호
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• pp.179-196
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• 2018

The purpose of this study was to investigate the measurement equivalence and to suggest application ways in teaching aptitude and personality test results for pre-service mathematics teachers between a graduate school of education and a college of education. This study analyzed the scores of the teaching aptitude and personality test of 36 pre-service mathematics teachers enrolled in a graduate school of education and 111 pre-service mathematics teachers in a college of education by performing a multivariate generalizability analysis. The main results were as follows. First, graduate's pre-service mathematics teachers had a higher level of teaching aptitude and personality than that of college's pre-service mathematics teachers based on the total scores. In addition, graduate's pre-service mathematics teachers had higher levels of teaching aptitude and personality than those of college's pre-service mathematics teachers except for a creativity application domain based on the sub-domain scores. Second, cognitive domains were measured more precisely but affective domains were measured less precisely for graduate's pre-service mathematics teachers than for college's pre-service mathematics teachers. Third, regardless of school levels, Cronbach's ${\alpha}$ values, which might be overestimated by applying the classical test theory, were higher than dependability coefficients. Fourth, this study showed a somewhat negative result in ensuring the measurement equivalence for a problem solving exploration domain. However, regardless of school levels, this study indicated that the overall measurement was generally reliable on composite scores. Based on these results, it was confirmed that multivariate generalizability methodologies' approach can be useful for exploring the measurement equivalence issues. Finally, this study suggests how to utilize the results of the test, how to apply a multivariate generalizability analysis for detecting the measurement equivalence, and how to develop future research based on limitations.

• 디지털융복합연구
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• 제13권9호
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• pp.129-136
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• 2015

본 논문은 학제간 연구의 대표적인 사례인 빅데이터 연구가 어떤 주제로 구성되어 있는지를 상향식 접근법을 이용하여 분석한다. 분석을 위해서 연구재단에서 제공하는 학술지 인용색인시스템을 이용하였다. 영문 키워드 "big data"로 모든 등재지와 등재후보지를 대상으로 검색을 하여 이것을 원천 데이터로 하였다. 논문 저자가 직접 제공하는 키워드를 본 연구에서 사용하기 위해서 정제작업을 거친 후, 주요 키워드 분포, 참여 저널의 성격 분포, 참여저자 수의 분포, 연도별 키워드 분포 등을 이용하여 빅데이터 연구주제의 구조를 설명하였다. 식별된 주요 키워드들은 사회네트워크 분석, 하둡, 맵리듀스, 개인정보/보호, 클라우드 컴퓨팅, 시각화, 데이터마이닝 등이다. 또한 빅데이터가 지속가능하고 융복합적인 경영혁신 도구로 사용되기 위해 향후 추가적으로 보완되어야 할 연구 키워드들을 제안한다.

• 한국전기전자재료학회논문지
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• 제27권4호
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• pp.238-243
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• 2014

This paper dealt with the measurement and analysis of partial discharge (PD) under high voltage direct current (HVDC) in SF6 gas. Electrode systems such as a protrusion on conductor (POC), a protrusion on enclosure (POE), a crack on epoxy plate and a free particle (FP) were fabricated to simulate the insulation defects. The analysis system was designed with a Time-Frequency (T-F) map algorithm programed based on LabVIEW. This can arrange the acquired PD pulses into frequency and time domain. A HVDC power source is composed of a transformer (220 V/50 kV), a diode (100 kV) and a capacitor (50 kV, 0.5 ${\mu}F$). The gap between the electrodes is 3 mm, and the $SF_6$ gas was set at 5 bar. PD pulses were detected by a 50 ${\Omega}$ non-inductive resistor. In the analysis, PD pulses were distributed below 0.5 MHz and 20 ns ~ 35 ns for the POC, 0.7 MHz ~ 1.7 MHz, below 0.6 MHz and 10 ns ~ 40 ns and 60 ns ~125 ns for the POE, below 0.1 MHz and 135 ns ~ 215 ns for the crack, and below 1.6 MHz and 250 ns for the FP.

• Molecules and Cells
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• 제44권10호
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• pp.758-769
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• 2021

Calcium homeostasis modulator 1 (CALHM1) is a membrane protein with four transmembrane helices that form an octameric ion channel with voltage-dependent activation. There are four conserved cysteine (Cys) residues in the extracellular domain that form two intramolecular disulfide bonds. We investigated the roles of C42-C127 and C44-C161 in human CALHM1 channel biogenesis and the ionic current (I_CALHM1). Replacing Cys with Ser or Ala abolished the membrane trafficking as well as I_CALHM1. Immunoblotting analysis revealed dithiothreitol-sensitive multimeric CALHM1, which was markedly reduced in C44S and C161S, but preserved in C42S and C127S. The mixed expression of C42S and wild-type did not show a dominant-negative effect. While the heteromeric assembly of CALHM1 and CALHM3 formed active ion channels, the co-expression of C42S and CALHM3 did not produce functional channels. Despite the critical structural role of the extracellular cysteine residues, a treatment with the membrane-impermeable reducing agent tris(2-carboxyethyl) phosphine (TCEP, 2 mM) did not affect I_CALHM1 for up to 30 min. Interestingly, incubation with TCEP (2 mM) for 2-6 h reduced both I_CALHM1 and the surface expression of CALHM1 in a time-dependent manner. We propose that the intramolecular disulfide bonds are essential for folding, oligomerization, trafficking and maintenance of CALHM1 in the plasma membrane, but dispensable for the voltage-dependent activation once expressed on the plasma membrane.

• 공학교육연구
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• 제17권5호
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• pp.33-40
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• 2014

This study aimed to analyze the current trends and future issues of the creativity development research in the Korean engineering education. The analysis led to categorizing the previous research topics into the following five domains: (i)systems and media (ii)instructional strategies and methodologies (iii)curriculum (iv)evaluation and (v) learner characteristics. The analysis further deduced more detailed sub-domains from each of the five domains. In addition, this study investigated publication frequencies of each domain and sub-domains and grasped specific flows of past research topics. Finally, based upon the analysis, this study drew implications and ramifications for creativity development studies in the Korean engineering education, elucidated future issues and refined upcoming research agendas. It is hoped that this research will articulate the present status of the studies that deal with creative education catering to engineering students and help set paths for future research.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2008년도 춘계학술대회논문집
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• pp.534-538
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• 2008

The vehicle system is exposed to random source in service. Therefore, it is important to consider dynamic effect of the system. But, fatigue analysis is traditionally performed by using time signal of loading. To obtain dynamic effect of resonance, we carried out resonance durability analysis with frequency response and the dynamic load on frequency domain. The study shows that the damage considering resonant frequency of fuel tank system can be effectively estimated.

• Geomechanics and Engineering
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• 제7권2호
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• pp.149-164
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• 2014

One of the most advanced classes of techniques for ground response analysis is based on the use of Transfer Functions. They represent the ratio of Fourier spectrum of amplitude motion at the free surface to the corresponding spectrum of the bedrock motion and they are applied in frequency domain usually by FFT method. However, Fourier spectrum only shows the dominant frequency in each time step and is unable to represent all frequency contents in every time step and this drawback leads to inaccurate results. In this research, this process is optimized by decomposing the input motion into different frequency sub-bands using Wavelet Multi-level Decomposition. Each component is then processed with transfer Function relating to the corresponding component frequency. Taking inverse FFT from all components, the ground motion can be recovered by summing up the results. The nonlinear behavior is approximated using an iterative procedure with nonlinear soil properties. The results of this procedure show better accuracy with respect to field observations than does the Conventional method. The proposed method can also be applied to other engineering disciplines with similar procedure.