• Journal of Korea Water Resources Association
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• v.41 no.5
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• pp.455-462
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• 2008

In this research, a distributed rainfall-runoff model based on physical kinematic wave was developed to simulate temporal and spatial distribution of flood discharge considering grid rainfall and grid based hydrological information. The developed model can simulate temporal change and spatial distribution of surface flow and sub-surface flow during flood period, and input parameters of ASCII format as pre-process can be extracted using GIS such as ArcGIS and ArcView. Output results of ASCII format as post-process can be created to express distribution of discharge in the watershed using GIS. The Namgang Dam Watershed was divided into square grids of 500m resolution and calculated by kinematic wave into an outlet through channel networks to review capability of the developed model. The model displayed precise results to be compared to the hydrograph.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.3A
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• pp.249-253
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• 2006

We propose a new beamforming algorithm, which is based on simplex downhill optimization method in the presence of pilot channels in cdma2000 reverse-link, for the rake structure antenna array in DS/CDMA communication system. Our approach uses the desired signal(pilot) covariance matrix and the interference covariance matrix. The beamforming weights are made according to maximum SINR criteria using simplex downhill optimization procedure. Our proposed scheme provides lower computational load, better convergence speed, better performance than existingadaptive beamforming algorithm. The simplex downhill method is well suited to finding the optimal or sub-optimal weight vector, since they require only the value of the deterministic function to be optimized. The rake beamformer performances are also evaluated under several set of practical parameter values with regard to spatial channel model. We also compare the performance between conventional rake receiver and the proposed one under same receiving power.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.1C
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• pp.79-85
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• 2008

Dirty Paper Coding(DPC) can achieve the sum capacity of a multiuser multiple-input multiple-output(MU MIMO) broadcast channels. However, due to the high computational complexity of the successive encoding and decoding, deploying DPC in real systems is impractical. As one of practical alternatives to DPC, Block Diagonalization(BD) was researched. BD is an extension of the zero-forcing preceding technique that eliminates interuser interference(IUI) in downlink MIMO systems. Though BD has lower complexity than DPC, BD shows poor sum capacity performance. We show that sum capacity performance of BD is degraded due to no IUI constraint. Then, we modify BD to improve its sum capacity performance with relaxing the constraint and sub optimal channel set searching. With simulation results, it can be verified that our modification in BD induces some improvement in sum capacity performance.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.5B
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• pp.469-479
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• 2009

The GEM frame is used a mean to deliver the variable length user data and consists of the header and the payload in the G-PON system. The HEC field of header protects contents of the header and is used to maintain GEM frame synchronization at the same time. When an LCDG (Loss of GEM Channel Delineation) occurs while receiving frames, the receiver have to discard corrupted frames until acquiring the synchronization again. Accordingly, high-speed synchronization method is required to minimize the frame loss. In this paper, we suggest not only a main state machine but a sub-state machine to reduce the frame loss when undetectable errors occurred in the GEM header. Also, we provide a more efficient and fast parallel structure to detect the starting point of the header. Finally, the proposed method is implemented with the FPGA and verified by the logic analyzer.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.8
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• pp.661-669
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• 2017

This paper describes an MMTI(Maritime Moving Target Indicator) for periscope detection in airborne radar. Firstly, we analyze the characteristics of sea clutter, sea targets. Secondly, we study the differences between GMTI(Ground Moving Target Indicator) and MMTI. This paper proposes an optimal MMTI operating environment and method. We also suggest a signal processing algorithm using STAP(Space-Time Adaptive Processing) for detecting small RCS target moving low speed. The detection probability for moving target with MDV(Minimum Detectable Velocity) is simulated under various RCS and multi-channel system. Finally, we analyze the major performance for range, velocity and azimuth accuracy.

• Journal of Microbiology and Biotechnology
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• v.23 no.1
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• pp.125-130
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• 2013

Influenza viruses cause significant morbidity and mortality in humans through epidemics or pandemics. Currently, two classes of anti-influenza virus drugs, M2 ion-channel inhibitors (amantadin and rimantadine) and neuraminidase inhibitors (oseltamivir and zanamivir), have been used for the treatment of the influenza virus infection. Since the resistance to these drugs has been reported, the development of a new antiviral agent is necessary. In this study, we examined the antiviral efficacy of the plant extracts against the influenza A/PR/8/34 infection. In vitro, the antiviral activities of the plant extracts were investigated using the cell-based screening. Three plant extracts, Thuja orientalis, Aster spathulifolius, and Pinus thunbergii, were shown to induce a high cell viability rate after the infection with the influenza A/PR/8/34 virus. The antiviral activity of the plant extracts also increased as a function of the concentration of the extracts and these extracts significantly reduced the visible cytopathic effect caused by virus infections. Furthermore, the treatment with T. orientalis was shown to have a stronger inhibitory effect than that with A. spathulifolius or P. thunbergii. These results may suggest that T. orientalis has anti-influenza A/PR/8/34 activity.

• The Korea Journal of Herbology
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• v.31 no.6
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• pp.63-71
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• 2016

Objective : To suggest a scientific evidence of Aconitum carmichaeli Debx. (Aconiti Lateralis Radix Preparata: ALRP) as one of cooling and heating medicines on the regulation of body temperature, we investigated the effects of ALRP water extract on hypothyroidism. Methods : Hypothyroidism was induced by intradermal injection with PTU for 4 weeks in SD rats. ALRP extract or L-thyroxine as a control drug was orally administrated for 2 weeks with PTU injection in rats. The physiological and serological parameters were measured in rats. The histological change of thyroid tissues was observed by H&E staining, and also the expression of thermo-regulating proteins was determined by Western blot in dorsal root ganglia and brain tissues of rats. Results : The administration of ALRP extract in PTU-induced hypothyroidism rats was significantly increased body temperature, but did not changes on body weight, food and water intake. ALRP extract did not effect on the levels of TSH and T4 in the hypothyroidism rats. ALRP extract significantly decreased the levels of GPT, glucose, HDL-cholesterol, LDL-cholesterol, and total cholesterol in the hypothyroidism rats. In histological observation, the enlarged epithelium and atrophic follicles with higher concentration of follicular cells on hypothyroidism were improved by ALRP extract. In addition, ALRP extract increased the expression of TRPV1 and TRPM8 ion channel proteins in hypothyroidism rats. Conclusion : These results indicate that ALRP extract can improve PTU-induced hypothyroidism through regulation of body temperature and lipid accumulation. The action mechanism of ALRP extract is related with body temperature control by thermoregulation with TRP ion channels.

• Journal of the Korea Convergence Society
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• v.9 no.12
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• pp.441-447
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• 2018

This study aimed to investigate the effect of firefighters' social capital on subjective happiness. This research was conducted from Jun 12 to Aug 25, 2017, and a descriptive analysis, t-test, hierarchical regression analysis was carried out based on the results of a survey with 351 firefighters in Gyeonggi-do to verify the research hypothesis. As a result, it was revealed that network(${\beta}=.315$, p<.001), trust(${\beta}=.293$, p<.01), cooperation(${\beta}=.225$, p<.01) and trust among other sub-variables of firefighters' social capital had significant effects on subjective happiness. Based on the results, this research suggested that various measures to strengthen social capital would be required in order to improve fire-fighters' happiness: efforts to increase trust within the organization, political support for vitalizing formal network as a communication channel among firefighters organizations, encouraging interest in the community and promoting informal network such as volunteer work, developing transparency in operating the organizational policy and system, etc.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.12
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• pp.924-934
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• 2018

This paper describes the development and measurement results of C-band planar active phase array antenna for detecting and tracking radar(weapon-locating radar). The antenna is designed with 14 sub-arrays(12 main channels and 2 sidelobe blanking channels and approximately 3,000 elements of transmit-receive channel) to generate transmit and digital receive patterns. Using a near-field measurements facility, G/N, transmit patterns, and received patterns are measured. Receive patterns are implemented with digital beamforming by signal processing. The measurement results demonstrate that antenna design specifications were fulfilled.

• Yonsei Medical Journal
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• v.59 no.9
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• pp.1131-1137
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• 2018

Purpose: Previous reports have shown that hyperglycemia-induced inhibition of transient receptor potential vanilloid sub type 4 (TRPV4), a transient receptor potential ion channel, affects the severity of hearing impairment (HI). In this study, we explored the role of TRPV4 in HI using HEI-OC1 cells exposed to high glucose (HG). Materials and Methods: HEI-OC1 cells were cultured in a HG environment (25 mM D-glucose) for 48 hours, and qRT-PCR and Western blotting were used to analyze the expression of TRPV4 at the mRNA and protein level. TRPV4 agonist (GSK1016790A) or antagonist (HC-067047) in cultured HEI-OC1 cells was used to obtain abnormal TRPV4 expression. Functional TRPV4 activity was assessed in cultured HEI-OC1 cells using the MTT assay and a cell death detection ELISA. Results: TRPV4 agonists exerted protective effects against HG-induced HI, as evidenced by increased MTT levels and inhibition of apoptosis in HEI-OC1 cells. TRPV4 overexpression significantly increased protein levels of phosphorylated p38 mitogen-activated protein kinase (p-p38 MAPK), while TRPV4 antagonists had the opposite effect. Our results indicated that TRPV4 is a hyperglycemia-related factor that can inhibit cell proliferation and promote cell apoptosis by activating the MAPK signaling pathway in HEI-OC1 cells. Conclusion: Our results show that the overexpression of TRPV4 can attenuate cell death in HEI-OC1 cells exposed to HG.