• 제목/요약/키워드: Studies

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알레르기 질환에서 장내미생물 조절을 통한 한약의 효과 연구동향 (Current Trends of Traditional Herbal Medicine Research on Allergic Disease with Dysbiosis)

  • 이윤정;김민희
    • 한방안이비인후피부과학회지
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    • 제37권1호
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    • pp.57-68
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    • 2024
  • Objectives : The purpose of this study is to analyze the current trends of various herbal medicine research on allergic disease with dysbiosis. Methods : Electronic searches were performed using Pubmed, Research Information Sharing Service(RISS), Korean studies Information Service System(KISS), Oriental medicine Advanced Searching Integrated System(OASIS). Results : We analyzed ten studies on the effect of herbal medicine on allergic disease with dysbiosis. Eight studies were animal experimental studies, and two were randomized clinical trial(RCT) study and one-group pretest-posttest research, respectively. Among the studies, three studies were on atopic dermatitis, two on allergic rhinitis, and five on asthma. All different herbal medicines were used in the studies. Changes in gut microbiota composition were observed in nine studies except for 1 RCT study. In eight animal experimental studies, there was significant reduction in allergy-related inflammatory markers. Six studies evaluated the change of metabolites related to gut microbiota and three of them showed significant increase in short-chain fatty acids(SCFA). Conclusion : This study provides current trends of studies on herbal medicine research on allergic disease with dysbiosis. Most research is conducted using animal experiments, and this is a relatively recent trend. These studies offer basic knowledge on the correlation between herbal medicine, gut microbiota, and anti-inflammatory effects in allergic disease.

비만의 한방 치료에 대한 국내 임상 논문 고찰 (Review of Clinical Studies on Oriental Medicine Treatment for Obesity in the Korean Literature)

  • 문수정;공재철;권영달;송용선;한아름;권영미;이수경
    • 한국한의학연구원논문집
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    • 제16권3호
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    • pp.85-93
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    • 2010
  • The aim of this review is to investigate clinical studies on oriental medicine treatment for obesity in Korean literature and to propose for the better method of clinical studies in order to seek more effective treatment. Electric searches were performed with NDSL, National assembly library, RISS4U, DBPIA, KISS, KMBASE, KoreaMed, Korean traditional knowledge portal and Oasis. Also, 21 major journals associated with oriental medicine in Korea were searched manually. Eighty three studies were included and analyzed in terms of study design, subjects, interventions, results and evaluation of safety. The numbers of controlled, non-controlled and case studies are respectively 26(31%), 43(52%) and 14(17%). Studies using sample size less than 30 accounts for 49% and studies using subjects diagnosed as obese or overweight by specific criteria were 35(42%). Studies which used more than 2 interventions or co-interventions were 76%. Clinical studies which used single herbal medicine were few and clinically studied single herbal medicine were limited to ephedra. More than half of 83 studies were studied for 8 weeks and less. 12% of 69 studies(except case studies) were not statistically analyzed and studies which evaluated safety of intervention were 22(27%) and reported adverse events were 9(11%). To improve the quality of clinical studies on oriental medicine treatment for obesity, studies need to use restricted number of interventions and subjects need to specifically diagnosed as overweight or obese. In addition, various kinds of single herbs need to be clinically studied based on experimental studies and herbalogy.

우리나라 만화 연구 경향 분석과 향후 과제 (The development of the comics studies in Korea)

  • 이상민;임학순
    • 만화애니메이션 연구
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    • 통권16호
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    • pp.1-20
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    • 2009
  • 본 연구는 우리나라 만화를 연구한 논문을 분석하여 그 경향을 살펴보는 데 초점을 두었다. 이를 위하여 우리나라 만화를 주제로 한 학술논문 664편을 연구 대상으로 삼았고, 정부와 공공 부문에서 추진한 만화 정책 관련 연구 개발 실태를 분석하였다. 이러한 연구의 배경은 우리나라에서 만화 연구가 1990년대 이후부터 중요한 관심분야로 대두되어 왔지만, 아직까지 만화의 학문적 정체성과 연구영역, 그리고 연구범위와 방법에 대해서는 정체성의 혼란을 경험하고 있다는 점과 지금까지 이루어진 만화 연구에 대한 학문적 성찰 작업이 이루어지지 않았다는 점에 있다. 만화 연구는 주로 교육학 전공자와 인문학 전공자들에 의해 이루어졌고 만화 연구 논문을 게재한 학술지도 교육학과 인문학 성향의 것이 절반 이상의 비중을 차지하고 있었다. 만화 연구 분야는 1980년대까지 만화가 미치는 부정적 영향에 대한 것이 주를 이루다가 1990년대에 이르면서 만화의 긍정적 영향에 대한 논문들이 나오기 시작했다. 만화텍스트에 대한 연구도 이 시기부터 이루어지기 시작했으며, 2000년대에 들어서서 만화정책, 만화산업, 만화도시 등에 대한 연구로 다양화되는 모습을 보였다. 그러나 아직 만화의 다양한 가치 창출의 힘에 대한 이론적, 실증적 연구가 충분하게 이루어지지 않고 있으며, 만화/만화산업/만화문화에 대한 담론 또한 활발하게 이루어지지 못하고 있는 실정이다. 앞으로 만화가 독립된 예술형식으로 그 위상을 정립하고, 문화영역의 중요한 요소로 그 가치를 구현하기 위해서는 만화연구가 체계화되고 활성화되어야 한다. 이와 관련하여 본 연구에서는 만화연구 방향의 몇 가지를 제시해 보았다. 첫째 만화 연구의 학문적 정체성 확보가 필요하다. 둘째 만화에 대한 학제적 연구가 활성화되고, 연구의 다양성이 확보되어야 한다. 셋째 만화지표 및 통계조사 연구를 강화해야 한다. 마지막으로 만화 박물관, 도서관의 활용, 만화 연구 커뮤니티의 활성화 등 만화 연구의 기반을 구축해야 한다.

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라틴아메리카 지역연구동향 및 개별국가연구 (Latin American Regional Study Trend and Individual Nation Study)

  • 차경미
    • 비교문화연구
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    • 제22권
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    • pp.203-221
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    • 2011
  • With the beginning of systemized research on Latin American region as a part of the third world in the mid-60s, Latin American regional studies in Korea acquired a steppingstone for development through the establishment of Hankook University of Foreign Studies Central & South American Regional Study, the creation of Central & South America Research Center, and Latin American Society established in the mid-80s. Latin American regional studies achieved quantitative and qualitative growth with the natioal globalization policy in the 90s, and research centers related to Latin America in Seoul National University, Pusan University of Foreign Studies, Dankook University, and Sunmoon University have contributed to the activation of regional studies. In spite of such achievements, Latin American regional studies, which have developed with 40 years of history, still possess problems that need to be solved. This study achieves qualitative analysis on theses published from 2000 to March 2001 in main Latin America regional study academic journals in Korea to analyze Latin American regional study trend of the recent 10 years in order to search measures for activating Latin American regional studies. Academic journals used in analysis include "Ibero America Research" of Seoul National University Research Center of Central & South America, Spain, "Central & South America Research" of Hankook University of Foreign Studies Research Center of Central & South America, "Ibero America Research" of Pusan University of Foreign Studies Central & South America Center, and "Latin America Research" published by Latin American Society. According to analysis on publication ratio of published theses according to field, it was presented that culture and politics fields occupied the highest ratio. Social and cultural fields, the elementary studies of regional research which have previously presented a weak research tendency, have achieved noticeable development during the past 10 years. According to analysis on researched nations, Latin America regional study was weighted in particular nations, and nations of economic size and political influence within region were selected as main subjects of research. Furthermore, several nations were not researched at all. For the last 10 years, the depth and width of the Latin America regional study had been decided by the degree of political, economic, social, and cultural significance occupied by the nation. It can be said that studies based on overall understanding on regional countries of Latin America have been relatively weak in individual nation study. Furthermore, studies that separate issues to achieve analysis based on the awareness theory of individual branches can be regarded dominant among studies based on entire Latin America. These studies still possess limitations in failing to deviate from the outline of particular region and topic.

학문 목적 한국어교육의 연구 유형 분류와 연구 방법의 동향 분석 (A Classification of Research Types and Trend Analysis of Research Methods in Korean for Academic Purposes)

  • 나원주;주현하;김영규
    • 한국어교육
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    • 제28권1호
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    • pp.79-111
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    • 2017
  • This study is a trend analysis study that discusses the current status and directions of research methods of KAP research. The existing trend ana lysis studies dealing with research methods have problems in that the classification criteria of the studies used are rough and different from each other, rendering comparison between studies being difficult, and do not comprehensively cover research methods of diversified KAP research. Therefore, this study examined the research methods of KAP research from a critical point of view and suggested a set of classification criteria and an analysis framework that can be used consistently in classification and analysis of future KAP research methods. Based on the theoretical background of second language studies and applied linguistics, this study revised and supplemented Brown (2015)'s research method types and selected 289 journals and theses/dissertations from 2012 to 2016 and classified them into a new analysis framework. The primary and secondary studies, which are the major categories, were 219 and 70, respectively, so it was confirmed that there were much more primary studies. The primary studies then were subdivided into 128 qualitative research studies, 142 survey research studies, and 23 quantitative research studies, pointing to the trend that survey and qualitative research methods were preferred. In the qualitative research approaches, there were 21 action research studies, which were used the most. In addition, such qualitative research approaches as case studies and narrative inquiries which were difficult to find in the past, have gradually increased, confirming that the diversification of research methods is becoming common. However, there were still many studies that did not explicitly put forward research questions and there were many studies that did not report reliability and effect sizes in quantitative research. Of the 23 quantitative studies, only 50% reported reliability, and only three reported effect sizes. In order to enable systematic reviews (meta-analysis) of quantitative research and expect quality improvement of research in future KAP research, reporting of quantitative research should be done more systematically. This study is meaningful in that a systematic and detailed analysis framework was proposed to classify various research methods in the future and that the problems and directions for improvement of the KAP research methods were discussed through the analysis of the research trend of the KAP studies for the last 5 years.

집속초음파 치료의 한의 임상 활용에 대한 고찰 (Clinical Application of Focused Ultrasound in Korean Medicine)

  • 최유민;이마음;허나연;이은희;최혁용;서형식;황의형;장인수
    • Korean Journal of Acupuncture
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    • 제40권3호
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    • pp.79-89
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    • 2023
  • Objectives : The purpose of this study is to investigate various application methods of focused ultrasound and apply them to clinical use in Korean medicine. Methods : Search was performed using the search engines of electronic databases, including PubMed, ScienceDirect, Cumulative Index to Nursing and Allied Health Literature (CINAHL), ScienceON, Oriental Medicine Advanced Searching Integrated System (OASIS), China National Knowledge Infrastructure (CNKI), Wanfang Data, Japan Science Technology Information Aggregator, Electronic (J-STAGE) and Citation Information by NII (CiNii), from inception to July 2023 without language limitation. Inclusion criteria were clinical studies including randomized controlled trials (RCTs), and animal experimental studies related with focused ultrasound treatments for acupoints or meridian sinews. Results : Total 17 papers, 7 for RCT, 6 for in vivo animal studies, and other experimental studies, were finally selected. Indications used in studies were shoulder pain, back pain, chronic back pain, and degenerative knee arthritis. In experimental studies, studies on animal models of hypoxic ischemic brain damage and hyperlipidemia were also conducted. As for the acupoints, LR3, LI4, and ST36 were used in clinical studies and, in animal experimental studies, GV20, KI1, and ST36 were used. As for the dose, 4 studies below 3 W/cm2 and 3 studies in the range of 0.625 to 5 W/cm2 in clinical studies, and all studies did not exceed 5 W/cm2. In animal experimental studies, 0.5 W/cm2, 2 W/cm2, 7.5 WW/cm2, 15 W/cm2, 10~20 W/cm2 were used. In all three studies describing the penetration depth during irradiation, it was less than 1 cm. Conclusions : We suggest that focused ultrasound is an appropriate treatment tool for stimulating the acupoints to transfer heat energy. Future studies with rigorous and well-designed RCTs for various diseases will be required to ascertain the focused ultrasound stimulate acupoints or meridian sinews.

음악요법이 치매의 초조행동에 미치는 효과: 체계적 문헌고찰 및 메타분석 (Effects of Music Therapy on Agitation in Dementia: Systematic Review and Meta-analysis)

  • 공은희;박명화
    • 성인간호학회지
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    • 제27권1호
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    • pp.106-116
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    • 2015
  • Purpose: The purpose of this review was to assess the quality and to evaluate the effectiveness of music interventions in reducing agitation in older adults with dementia. Methods: Randomized controlled studies and randomized crossover studies were identified by searching MEDLINE, EMBASE, CINAHL, PsycINFO, AGELINE, Cochrane Central Register of Controlled Trials, Korea Med, Kmbase, RISS, National Assembly Digital Library, KISS, and RICH. Two reviewers independently retrieved articles, extracted data, and assessed the quality of studies. Results: In total, 10 studies were selected from 1095 unique citations. All included studies were conducted in long term care settings. Overall, risk of bias for included studies was low to moderate. The weighted average effect size across studies was -0.39 (95%CI [-0.69, -0.10], p=.009, $I^2=63%$). Music therapy was effective to reduce agitation of the older adults with dementia. Conclusion: Music intervention can be an effective non-pharmacological intervention for the reduction of agitation in dementia. Future studies need to use rigorous research method and to provide description of research methods in greater detail. In addition, future studies are required to explore the effects of music therapy according to severity of agitation and dementia.

근로자의 스트레스에 대한 국내 간호 논문 분석($1981{\sim}2000$) (An Analysis of Studies of Workers' Stress conducted in Korea from 1981 to 2000)

  • 윤순녕;김정희
    • 지역사회간호학회지
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    • 제13권4호
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    • pp.618-628
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    • 2002
  • The purposes of this study were to identify patterns and trends of nursing studies of workers' stress conducted in Korea over the last two decades, and to suggest the direction of future research activities. Research studies of workers' stress were collected from the abstract and the title lists of studies using internet search. The total number of studies used for this study was 118. The analysis of these studies showed that the studies of workers' stress have increased rapidly since 1995, but most of them were non-experimental design studies. They tended to be conducted more on nurses, and used confusedly in stress terms. Instruments developed by the authors were the most popular. Moreover, the organizational variables of the stress-related concept were barely used except nurses' stress. Therefore, it was needed to identify and clarify the terms of stress among the authors, and to develop the workers' stress management programs and examine their effects. Especially studies that include the organizational variables of workers' stress need to be done in the future.

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고혈압 환자를 대상으로 한 기공운동 임상연구 방법론 고찰 (Review of Clinical Trials Using Qigong Exercise on Patients with Hypertension)

  • 정희정;박지은;류연;최선미
    • Korean Journal of Acupuncture
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    • 제28권3호
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    • pp.177-186
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    • 2011
  • Objectives : The aim of this study is to review clinical trials using Qigong exercise on patients with hypertension and to assess their methodology and results. Methods : Electronic literature searches for clinical trials (randomized trial, non-randomized trial, before-after study) of Qigong exercise were performed in 21 electronic databases (5 international databases and 16 Korean databases). English, Korean or Chinese articles were included. Laboratory or animal studies were excluded. Results : A total of 11 studies met the inclusion criteria. Five randomized controlled trials, Four non-randomized trials and two before-after studies were included. Seven studies used self-developed Qigong exercise. Two studies used Guolin Qigong exercise and two studies used Qigong exercise with an anti-hypertension drug. Of the nine randomized trials or non-randomized trials, four studies used an anti-hypertension drug control and three studies used waiting list controls. Compared to baseline, a change in blood pressure after the Qigong exercise treatment was significant in all studies. However, the results effect of blood pressure between Qigong exercise and controlled trials were not consistent. Conclusions : There are low-quality clinical trials of Qigong exercise for hypertension. To evaluate the effects of Qigong exercise, more rigorous trials are warranted.

신생아 통증완화 중재 관련 국내 연구분석 (Analysis of Research Related to the Neonatal Pain Relief Intervention in Korea)

  • 오진아;노인숙
    • 부모자녀건강학회지
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    • 제12권2호
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    • pp.160-176
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    • 2009
  • Purpose: The purpose of this study was to identify patterns and trends of studies, analyze the research, and improve direction of nursing research related to the neonatal pain relief intervention in Korea. Method: The studies were selected from dissertation, nursing journals and others in Korea. Result: Until 1995, there were no studies related to the neonatal pain relief intervention. The most studies have been increased rapidly after 2005. Pure of true experimental design of research design was used 5, Quasi experimental design was 7, preexperimental design was 7. Participants were preterm baby was 8, full-term baby was 9, and preterm and full-term baby was 2. Utilization of instruments as follows: NIPS, PIPP, ABSS, NFCS, pulse oximeter, EKG monitoring, and stethoscope. Contents of the research studies were classified 4 different types, such as studies of about the effect of auditory stimulation, taste stimulation, tactile stimulation, and topical anesthetic cream. The results of 25 studies were effective for the neonatal pain relief, but the results of 5 studies weren't. Conclusion: In the future studies need to develop the various instrument which is assessment of neonatal pain. It is important to the integrated by meta analysis. Additionally, we should develop protocol nursing intervention for the effective pain release.

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