• 제목/요약/키워드: Structure-activity relation

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그레마스 기호학적 접근을 통한 애니메이선 캐릭터 분석 -장편 애니메이션 "슈렉" 을 중심으로- (A Study of 'Greimas' Semiological Approach in Animation Character)

  • 임운주
    • 한국콘텐츠학회논문지
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    • 제9권5호
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    • pp.99-106
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    • 2009
  • 본 연구는 애니메이션 작품 <슈렉>의 캐릭터를 그레마스 기호학적 이론을 바탕으로 분석하였다. 애니메이션은 하나의 내러티브 속에서 나타나는 캐릭터간의 행위들로 이루어진다. 이러한 캐릭터의 행위들은 캐릭터 가치체계와 의미를 나타낸다. 겉으로 드러나지 않은 잠재적 가치가 발화되는 과정에서 서열적인 가치체계가 생성되고, 캐릭터의 사고 및 행동이 다른 캐릭터들과 다양한 관계의 망을 형성함으로써 의미를 확장해 나간다. 이러한 관점에서 캐릭터의 행위 구조에서 나타난 캐릭터의 체계와 의미를 그레마스 행위소 모델과, 기호학적 4각형 모델을 통해 애니메이션 캐릭터에서 나타난 체계적 특징들과 상호관계의 망 속에서 나타난 의미구조를 분석하고자 하였다.

Matrix Metalloproteinases and Cancer - Roles in Threat and Therapy

  • Yadav, Lalita;Puri, Naveen;Rastogi, Varun;Satpute, Pranali;Ahmad, Riyaz;Kaur, Geetpriya
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권3호
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    • pp.1085-1091
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    • 2014
  • Matrix metalloproteinases (MMPs) are a family of zinc dependent extracellular matrix (ECM) remodelling endopeptidases having the ability to degrade almost all components of extracellular matrix and implicated in various physiological as well as pathological processes. Carcinogenesis is a multistage process in which alteration of the microenvironment is required for conversion of normal tissue to a tumour. Extracellular matrix remodelling proteinases such as MMPs are principal mediators of alterations observed in the microenvironment during carcinogenesis and according to recent concepts not only have roles in invasion or late stages of cancer but also in regulating initial steps of carcinogenesis in a favourable or unfavourable manner. Establishment of relationships between MMP overproduction and cancer progression has stimulated the development of inhibitors that block proteolytic activity of these enzymes. In this review we discuss the MMP general structure, classification, regulation roles in relation to hallmarks of cancer and as targets for therapeutic intervention.

Pd/cordierite 촉매상에서 메탄의 연소 특성 고찰 (A Study on the Combustion Characteristics over Pd/cordierite Catalyst)

  • Cho, Won-Ihl;Oh, Young-Sam;Park, Dal-Ryung;Baek, Young-Soon;Pang, Hyo-Sun;Mok, Young-Il
    • 에너지공학
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    • 제6권1호
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    • pp.34-40
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    • 1997
  • 자동차 촉매인 Pd/cordierite 촉매상에서 메탄의 연소시험을 통하여 천연가스 이용기술 활용가능성에 대해서 고찰하였다. 중고온 연소에서 알맞은 비표면적 18.7$m^2$/g 을 갖으며 안정한 구조를 확인하였다. 메탄 연소 반응시 활성화에너지는 19.2 kcal/mol로써 비교적 우수한 활성을 보여주었으며, 메탄 연소 반응의 승온과 온도를 내리면서 촉매의 비활성 특성을 보여주는 활성 히스테리시스 현상을 관찰하였다. Pd/cordierite 촉매상에서 반응온도 $700^{\circ}C$이하에서 공간속도와 공연비를 변화시키면서 메탄 연소특성을 수행하였다.

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기계적 자극에 대한 휴지기를 포함한 교근의 근전도 신호 모델링 (Masseteric EMG Signal Modeling Including Silent Period After Mechanical Stimulation)

  • 김덕영;이상훈;이승우;김성환
    • 대한전기학회논문지:시스템및제어부문D
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    • 제50권11호
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    • pp.541-549
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    • 2001
  • The term 'silent period(SP)' refers to a transitory, relative or absolute decrease electromyography(EMG) activity, evoked in the midst of an otherwise sustained contraction. Masseteric SP is elicited by a tap on the chin during isometric contraction of masseter muscle. In this paper, a new EMG signal generation model including SP in masseter muscle is proposed. This work is based on the anatomical structure of trigeminal nerve system that related on temporomandibular joint(TMJ) dysfunction. And it was verified by comparing the real EMG signals including SP in masseter muscle to the simulated signals by the proposed model. Through this studies, it was shown that SP has relation to variable neurophysiological phenomena. A proposed model is based on the control system theory and DSP(Digital Signal Processing) theory, and was simulated using MATLAB simulink. As a result, the proposed SP model generated EMG signals which are similar to real EMG signal including normal SP and an abnormal extended SP. This model can be applied to the diagnosis of TMJ dysfunction and can effectively explain the origin of extended SP.

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Hydrogenation of Ethyl Acetate to Ethanol over Bimetallic Cu-Zn/SiO2 Catalysts Prepared by Means of Coprecipitation

  • Zhu, Ying-Ming;Shi, Xin Wang Li
    • Bulletin of the Korean Chemical Society
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    • 제35권1호
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    • pp.141-146
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    • 2014
  • A series of bimetallic Cu-Zn/$SiO_2$ catalysts were prepared via thermal decomposition of the as-synthesized $CuZn(OH)_4(H_2SiO_3)_2{\cdot}nH_2O$ hydroxides precursors. This highly dispersed Cu-solid base catalyst is extremely effective for hydrogenation of ethyl acetate to ethanol. The reduction and oxidation features of the precursors prepared by coprecipitation method and catalysts were extensively investigated by TGA, XRD, TPR and $N_2$-adsorption techniques. Catalytic activity by ethyl acetate hydrogenation of reaction temperatures between 120 and $300^{\circ}C$, different catalyst calcination and reduction temperatures, different Cu/Zn loadings have been examined extensively. The relation between the performance for hydrogenation of ethyl acetate and the structure of the Cu-solid base catalysts with Zn loading were discussed. The detected conversion of ethyl acetate reached 81.6% with a 93.8% selectivity of ethanol. This investigation of the Cu-Zn/$SiO_2$ catalyst provides a recently proposed pathway for ethyl acetate hydrogenation reaction to produce ethanol over Cu-solid base catalysts.

Wiki 기반 협력학습에서 적응적 내비게이션 시스템이 그룹 활동에 미치는 효과 (Effectiveness of Adaptive Navigation System for Group Activity at the Wiki-based Collaborative Learning)

  • 한희섭;김현철
    • 컴퓨터교육학회논문지
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    • 제9권1호
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    • pp.41-48
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    • 2006
  • 위키는 분산 환경의 협력학습 활동에 매우 효율적인 도구임이 최근 여러 실험을 통하여 연구되어 왔다. 위키는 구성원간의 지식공유가 효율적으로 이루어 질 수 있는 기능을 제공하고는 있으나, 페이지와 링크의 동적인 변화로 인한 내용구조의 복잡성으로 인하여 각 구성원이 내용구조를 전체적으로 파악하거나 자신에게 필요한 페이지를 효율적으로 찾기 힘든 단점이 있다고 볼 수 있다. 본 연구에서는 그룹 구성원들에 의한 페이지의 변화가 많이 발생하는 온라인 프로젝트 협력학습활동에서 그룹의 각 구성원에게 내용 구조와 자신에게 관심 있는 활동 페이지를 개별적으로 안내해줄 수 있는 적응적 내비게이션 안내 시스템을 개발하였다. 우리는 먼저 각 페이지와 구성원간의 관계 모델을 페이지 변화 정보와 개별 로그 정보를 사용하여 개발하고 이 모델을 사용하여 적응적 내비게이션 시스템을 설계 및 구현 하였으며, 이 적응적 시스템이 그룹 구성원간의 효율적인 정보공유 그리고 그로 인한 협력학습활동을 어떻게 촉진시켰는지를 현장 실험을 통하여 보여준다.

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국제물류관리와 전자적물류정보의 경쟁요인에 관한 실증연구 (An Empirical Study on the Competition Factor Electronic Logistics Information and International Logistics Management)

  • 곽현
    • 통상정보연구
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    • 제9권2호
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    • pp.257-283
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    • 2007
  • As Global industrial structure is diversified, multinational corporations accomplished fast internationalization to introduction of new management policy by development of an IT technology. Enterprise' business environment is changing transcending border. To overcome raging waves of change accident and to be secured enterprise's future, the logistics is recognized the third profit source joining in curtailment of sale enlargement, production cost. To seek cost saving or reform in logistics class that is last area of pursuit of profits within ancient city life in the fast lane from these viewpoint, importance of study that integrates and manages international logistics bases supply neck walk is emphasized. Specially, to meet on in terms of competitive power security regarding curtailment of logistics cost is available through link between logistics bases, various consumer's request, merchandise and service logistics management that supply fixed quantity as is reliable in right place at good season was embossed by point game plan of business management, and SCM efficiency anger of mortification international logistics activity importance of study that see at that dominate competitive advantage point bring. This study analyzes interrelation and presents model for integration of international logistics bases supply network with supply network habit at factor and supply chain, and supply network activity in integration of supply chain process and production. Also, it establishes following method of study to achieve study purpose for actual proof analysis for integration sequence of international logistics bases supply network. Specially, immersion of network and supply network, very high interrelation appeared by thing which is with international logistics base supply network integration. The integration of international logistics base supply network means that the enterprises which give trust and sincerity deal with market environment change positively and can decide proceeding of various cooperative work. Also, it means the possibility by necessity of cooperative relation and interdependence to continuous immersion and normative immersion, for the maintain of long business relations.

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군신좌사(君臣佐使)에 대한 연구 (Study on Prescriptions about Monarch(jun)${\cdot}$Minister(chen)${\cdot}$Adjuvant(zou)${\cdot}$Guide(shi) Theory)

  • 이태경;강정수;김병수
    • 동의생리병리학회지
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    • 제21권3호
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    • pp.596-604
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    • 2007
  • For countless time, many have been made in our oriental medicine. To understand such prescription and to use, we must study the monarch(jun), minister(chen), adjuvant(zou) and guide(shi) theory that is most of the prescription structure principle's the basis. The monarch is the center of the prescription. Two kind is greatly in the method to select the monarch, in the prescription. One method is that a medicinal herb of the high class of medical herb of the Sinnong's Classic becomes the monarch, and the other method is a medicinal herbs which there is most many qunantity in the prescription becomes the monarch. Additionally, a medicinal herbs name of a prescription name can become the monarch. The minister assist the monarch and this is a criteria of the prescription grouping with the monarch. The minister has close relation with the monarch. The adjuvant helps the monarch and the minister nature of drug or restains. So this makes the prescription effectiveness act accurately. The guide does the activity to help the harmony of the prescription and the activity to help the prescription to act in correct place. If we understand the monarch, minister, adjuvant and guide theory well, we have some advantage. The interpreting of the prescription comes to De easy. and, an application range of the prescription is enhanced. the increase and decrease of the medicinal herbs comes to be easy in the prescription. Finally that theory will be used for the principle to make new prescription.

지역사회 건강증진 간호활동의 프로그램 개발 (The Program Development of Nursing Activities for Community Health Promotion)

  • 박정희
    • 지역사회간호학회지
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    • 제10권2호
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    • pp.291-306
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    • 1999
  • Health promotion has come to the fore through new concept approach in consequence of the increase of chronic diseases. increase of medical cost and social trend of putting more emphasis on the individual responsibility for health. Studies of health promotion can be classified into two types: one is micro intervention method which is mainly focused on modifying individual life style and the other. macro intervention method in which they put another emphasis on the environment the individual is surrounded. in addition to modifying individual life style. This study belongs to the later. This study aims to develop nursing activities and program it for the purpose of community health promotion. The process of the study can be briefed as follows: to draw out nursing contents to intervene for community health promotion: to promote community health to develop nursing action indicators; to develop nursing action indicators for the development of main nursing activities. And those developed nursing activities are programmed systematically. The community health promotion program is composed of a hierarchical structure with nursing process that the nurses are supposed to apply to perform professional nursing. the level of nursing perform. the main items of nursing process. health promotion nursing indicators. health promotion nursing activities. The conclusion of this study according to objectives are as follows. First. community health promotion contents at individual and community level are remained revised and complemented and those at organizational level are developed. The developed main contents of community health promotion nursing are as follows. 1) Revised individual level nursing contents: 35 items. 2) Developed organizational level nursing contents: 24 items. 3) Revised community level nursing contents: 36 items. Second. for the development of the health promotion nursing action indicators. principles were set up and applied as follows. 1. Developed indicators should be provided with such qualities as comprehensiveness. diversity. developability, availability. practicability. 2. Developed indicators should be provided with functional abilities to measure the conditions and changes in any phenomena or state. inspect the development of the states. control the implementing program. evaluate the result of program and grasp what nurses should do. 3. Developed indicators should be provided with relevance and sequence. 4. Developed indicators should be undergo inspections from the expert. The developed community health promotion action indicators developed in this study. observing above mentioned principles. are total 330 indicators of 95 items. Third. when the main nursing activities were developed for each nursing action indicator. five priciples were set up in accordance with each nursing action indicators to decide main nursing activities. Main nursing activities developed observing those principles. are total 1273. Forth. for the programming of the developed nursing activities. three principles were set up. 1. The nursing activities are systematized in line with (nursing process) (nursing client) (key items of nursing process) (nursing action indicators for health promotion) (nursing activities). 2. The program is constructed in downward and hierarchical order. 3. The program is constructed not in relation to same level activities but in relation to high and low level activities. The process step of programming of developed main health promotion nursing activities are; Step 1. The Developed nursing action indicators are classified into nursing process. Step 2. The main nursing activities are allocated per each nursing action indicators. Step 3. The statement of main nursing activities are inspected. Step 4. The items of main nursing activities allocated by a certain nursing action indicators are sequenced. taking into consideration the elaborateness of activity. the sequency of activity. familiarity of activity. the difficulty of activity. the interest of activity. the frequency of activity. Step 5. The whole developed program should undergo comprehensive and critical inspections.

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반영적 추상화와 조작적 수학 학습-지도 (Reflective Abstraction and Operational Instruction of Mathematics)

  • 우정호;홍진곤
    • 대한수학교육학회지:수학교육학연구
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    • 제9권2호
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    • pp.383-404
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    • 1999
  • This study began with an epistemological question about the nature of mathematical cognition in relation to the learner's activity. Therefore, by examining Piaget's 'reflective abstraction' theory which can be an answer to the question, we tried to get suggestions which can be given to the mathematical education in practice. 'Reflective abstraction' is formed through the coordination of the epistmmic subject's action while 'empirical abstraction' is formed by the characters of observable concrete object. The reason Piaget distinguished these two kinds of abstraction is that the foundation for the peculiar objectivity and inevitability can be taken from the coordination of the action which is shared by all the epistemic subjects. Moreover, because the mechanism of reflective abstraction, unlike empirical abstraction, does not construct a new operation by simply changing the result of the previous construction, but is forming re-construction which includes the structure previously constructed as a special case, the system which is developed by this mechanism is able to have reasonability constantly. The mechanism of the re-construction of the intellectual system through the reflective abstraction can be explained as continuous spiral alternance between the two complementary processes, 'reflechissement' and 'reflexion'; reflechissement is that the action moves to the higher level through the process of 'int riorisation' and 'thematisation'; reflexion is a process of 'equilibration'between the assimilation and the accomodation of the unbalance caused by the movement of the level. The operational learning principle of the theorists like Aebli who intended to embody Piaget's operational constructivism, attempts to explain the construction of the operation through 'internalization' of the action, but does not sufficiently emphasize the integration of the structure through the 'coordination' of the action and the ensuing discontinuous evolvement of learning level. Thus, based on the examination on the essential characteristic of the reflective abstraction and the mechanism, this study presents the principles of teaching and learning as following; $\circled1$ the principle of the operational interpretation of knowledge, $\circled2$ the principle of the structural interpretation of the operation, $\circled3$ the principle of int riorisation, $\circled4$ the principle of th matisation, $\circled5$ the principle of coordination, reflexion, and integration, $\circled6$ the principle of the discontinuous evolvement of learning level.

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