• Molecules and Cells
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• v.38 no.9
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• pp.789-795
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• 2015

A chromosome territory is composed of chromosomal subdomains. The internal structure of chromosomal subdomains provides a structural framework for many genomic activities such as replication and DNA repair, and thus is key to determining the basis of their mechanisms. However, the internal structure and regulating proteins of a chromosomal subdomain remains elusive. Previously, we showed that the chromosome territory expanded after BAF53 knockdown. Because the integrity of chromosomal subdomains is a deciding factor of the volume of a chromosome territory, we examined here the effect of BAF53 knockdown on chromosomal subdomains. We found that BAF53 knockdown led to the disintegration of histone H2B-GFP-visualized chromosomal subdomains and BrdU-labeled replication foci. In addition, the size of DNA loops measured by the maximum fluorescent halo technique increased and became irregular after BAF53 knockdown, indicating DNA loops were released from the residual nuclear structure. These data can be accounted for by the model that BAF53 is prerequisite for maintaining the structural integrity of chromosomal subdomains.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.33 no.12
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• pp.39-47
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• 2005

An acoustic emission technique is applied to the tensile tests of the plastic specimen under the different test speeds and the structural integrity evaluation of the plastic shell structure. Several AE characteristics are acquired from the tensile tests and they are proven to be useful parameters in evaluating its structural integrity. The results shows that tensile strength has almost constant value over some higher speed region while revealing some increasing tendency in strength as the test speeds up in lower speed region. The crack initiation loads and locations are accurately evaluated during the static compression testing of the plastic shell structures by using acoustic emission technique.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.43 no.9
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• pp.773-780
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• 2015

In this paper, the structural integrity for a cylindrical vehicle in subsonic environments is verified. In order to confirm static structural safety for the cylindrical vehicle in extreme maneuver condition, the structure analysis and full-scale static structure test are carried out. The commercial finite element codes, MSC. Patran/Nastran is used for numerical simulation. The full-scale static structure test equipment consists of the counterbalance system, loading system and data acquisition system. Besides, the dynamic characteristics for the cylindrical vehicle are reviewed by performing an impact hammer test.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.1103-1109
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• 2023

Today, as the number of audio files submitted as legal evidence increases with the proliferation of smartphones, the integrity of audio files has become an important issue. Accordingly, the purpose of this study is to explore whether the metadata and file structure of audio files recorded on Samsung smartphones can be manipulated to be identical to the original. This study was based on Samsung smartphones, the most widely used in Korea, and conducted experiments on the built-in voice recording app and the 'Easy Voice Recorder' app, which is the most popular recording app. Through the experiments of this study, it was proven that the metadata and file structure of audio files can be manipulated. Therefore, this study reveals that metadata and file structure analysis have limitations in proving the integrity when audio files are analyzed for adoption as legal evidence. They also argue for the need to develop new voice file forgery technology that does not rely on metadata and file structure analysis.

• Journal of Animal Science and Technology
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• v.63 no.2
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• pp.211-247
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• 2021

Livestock species experience several stresses, particularly weaning, transportation, overproduction, crowding, temperature, and diseases in their life. Heat stress (HS) is one of the most stressors, which is encountered in livestock production systems throughout the world, especially in the tropical regions and is likely to be intensified due to global rise in environmental temperature. The gut has emerged as one of the major target organs affected by HS. The alpha- and beta-diversity of gut microbiota composition are altered due to heat exposure to animals with greater colonization of pathogenic microbiota groups. HS also induces several changes in the gut including damages of microstructures of the mucosal epithelia, increased oxidative insults, reduced immunity, and increased permeability of the gut to toxins and pathogens. Vulnerability of the intestinal barrier integrity leads to invasion of pathogenic microbes and translocation of antigens to the blood circulations, which ultimately may cause systematic inflammations and immune responses. Moreover, digestion of nutrients in the guts may be impaired due to reduced enzymatic activity in the digesta, reduced surface areas for absorption and injury to the mucosal structure and altered expressions of the nutrient transport proteins and genes. The systematic hormonal changes due to HS along with alterations in immune and inflammatory responses often cause reduced feed intake and production performance in livestock and poultry. The altered microbiome likely orchestrates to the hosts for various relevant biological phenomena occurring in the body, but the exact mechanisms how functional communications occur between the microbiota and HS responses are yet to be elucidated. This review aims to discuss the effects of HS on microbiota composition, mucosal structure, oxidant-antioxidant balance mechanism, immunity, and barrier integrity in the gut, and production performance of farm animals along with the dietary ameliorations of HS. Also, this review attempts to explain the mechanisms how these biological responses are affected by HS.

• Proceedings of the KIEE Conference
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• 1988.07a
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• pp.328-331
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• 1988

Sealed Interface Local Oxidation (SILO) technology has been investigated using a nitride/oxide/nitride three-layered sandwich structure. P-type silicon substrate was either nitrided by rapid thermal processing, or silicon nitride was deposited by LPCVD method. A three-layered sandwich structure was patterned either by reactive ion etch (RIE) mode or by plasma mode. Sacrificial oxidation conditions were also varied. Physical characterization such as cross-section analysis of field oxide, and electrical characterization such as gate oxide integrity, junction leakage and transistor behavior were carried out. It was found that bird's beak was nearly zero or below 0.1um, and the junction leakages in plasma mode were low compared to devices of the same geometry patterned in RIE mode, and gate oxide integrity and transistor behavior were comparable. Conclusively, SILO process is compatible with conventional local oxidation process.

• Composites Research
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• v.21 no.5
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• pp.15-22
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• 2008

This paper describes the results of structural integrity and crashworthiness of Automatic Guideway Transit(AGT) vehicle made of sandwich composites. The applied sandwich composite of vehicle structure was composed of aluminum honeycomb core and WR580/NF4000 glass fabric/epoxy laminate composite facesheet. Material testing was conducted to determine the input parameters for the composite facesheet model, and the effective equivalent damage model fer the orthotropic honeycomb core material. The finite element analysis using ANSYS v11.0 was dont to evaluate structural integrity of AGT vehicle according to JIS E 7105 and ASCE 21-98. Crashworthiness analysis was carried out using explicit finite element code LS-DYNA3D with the lapse of time. The crash condition was frontal accident with speed of 10km/h at rigid wall. The results showed that the structural integrity and crashworthiness of AGT vehicle were proven under the specified loading and crash conditions. Also, the modified Chang-Chang failure criterion was recommended to evaluate the failure modes of composite structures after crashworthiness event.

• ETRI Journal
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• v.32 no.2
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• pp.265-272
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• 2010

To supply a power distribution network with stable power in a high-speed mixed mode system, simultaneous switching noise caused at the multilayer PCB and package structures needs to be sufficiently suppressed. The uni-planar compact electromagnetic bandgap (UC-EBG) structure is well known as a promising solution to suppress the power noise and isolate noise-sensitive analog/RF circuits from a noisy digital circuit. However, a typical UC-EBG structure has several severe problems, such as a limitation in the stop band's lower cutoff frequency and signal quality degradation. To make up for the defects of a conventional EBG structure, a partially located EBG structure with decoupling capacitors is proposed in this paper as a means of both suppressing the power noise propagation and minimizing the effects of the perforated reference plane on the signal quality. The proposed structure is validated and investigated through simulation and measurement in both frequency and time domains.

• Journal of the Korean Society for Nondestructive Testing
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• v.20 no.4
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• pp.329-341
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• 2000

• Proceedings of the Korean Nuclear Society Conference
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• 2005.10a
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• pp.61-62
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• 2005