• Wind and Structures
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• v.14 no.4
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• pp.321-335
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• 2011

The vulnerability of roofing components of contemporary houses built in cyclonic regions of Australia is assessed for increasing wind speeds. The wind loads and the component strengths are treated as random variables with their probability distributions derived from available data, testing, structural analysis and experience. Design details including types of structural components of houses are obtained from surveying houses and analyzing engineering drawings. Wind load statistics on different areas of the roof are obtained by wind tunnel model studies and compared with Australian/New Zealand Standard, AS/NZS 1170.2. Reliability methods are used for calculating the vulnerability of roofing components independently over the roof. Cladding and batten fixings near the windward gable edge are found to experience larger negative pressures than prescribed in AS/NZS 1170.2, and are most vulnerable to failure.

• Vacuum Magazine
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• v.4 no.4
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• pp.18-22
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• 2017

Transmission electron microscopy (TEM) is a versatile and powerful technique that enables direct visualization of biological samples of sizes ranging from whole cell to near-atomic resolution details of a protein molecule. Thanks to numerous technical breakthroughs and monumental discoveries, 3D electron microscopy (3DEM) has become an indispensable tool in the field of structural biology. In particular, development of cryo-electron microscopy(cryo-EM) and computational image processing played pivotal role for the determination of 3D structures of complex biological systems at sub-molecular resolution. Here, basis of TEM and 3DEM will be introduced, especially focusing on technical advancements and practical applications. Also, future prospective of constantly evolving 3DEM field will be discussed, with an anticipation of great biological discoveries that were once considered impossible.

• Proceedings of the KSR Conference
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• 2006.11b
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• pp.981-989
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• 2006

The purpose of this article is to depict the relationship between the frames of leadership and the dependent variables such as job satisfaction, respect from subordinates, promotion, and effective attainment of unit objectives. To attain this purpose, for types of multiple leadership frames, such as structural, human resources, political, and symbolic frames were surveyed through questionnaire and analyzed by SPSS. The major findings are : 1) In general, the symbolic frame is an important factor having a stronger influence on job satisfaction, respect from subordinates, promotion, and effective attainment of unit objectives. 2) In details, the human resources frame shows a positive effects on job satisfaction and respect; the structural frame on effective attainment of unit objectives; the political frame, to a certain degree, on promotion; and the symbolic frame, especially on respect from subordinates, promotion, and effective attainment of unit objectives.

• Proceedings of the Korea Concrete Institute Conference
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• 2004.11a
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• pp.353-356
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• 2004

Nonlinear numerical analysis was performed to investigate the behavioral characteristics and failure mechanism of flexure -dominated structural walls with partially confined boundary elements. Based on the results, deformability of walls with partially confined boundary elements was evaluated, and a design method which can determine depth of confined boundary element according to given ductility demand, was developed. Also, effective details of laterally confining re-bars were proposed for boundary elements with rectangular cross-section. The design method can be used to choose the spacing of confining re-bars assuring the confining effect and constructability.

• Journal of Technology Innovation
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• v.13 no.3
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• pp.153-173
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• 2005

The Office of Science and Technology Innovation (OSTI) was created by a different method of organizational change from that of precedent administrative reforms. According to results of the new method, the OSTI case can be widely applied to other ministries as an alternative model for governmental reform. The theory part introduced two approaches of organizational reform, namely structural approach which focuses on the level of hierarchial authority and process approach which emphasizes the flow of information/expertise in organizational operation. It also discussed various ways of understanding for S&T policy coordination. After this, the paper reviewed details of the OSTI reform with special reference to implications for the mode of S&T policy coordination. It concludes that the OSTI may offer an opportunity to strengthen the coordination mechanism of the process approach.

• Structural Engineering and Mechanics
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• v.20 no.1
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• pp.123-141
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• 2005

Design details pertaining to the connection between some recently developed fiber reinforced polymer (FRP) composite deck systems and the supporting girders require openings through cells of the deck. This significantly changes the stress distribution in these components. As a result, the conventional assumptions that deck designs are controlled by their stiffness, and not strength, needs a closer examination. This paper proposes an analytical method to investigate the stress states and failure mechanisms using a type of "global-local" modeling perspective, incorporating classical lamination theory and first ply failure criterion with use of appropriate stress concentration factors around the cutouts. The use of a "smeared-stress" approach is presented as a potential means of simplifying certain FRP specific complexities, while still enabling prediction of overall failure.

• Steel and Composite Structures
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• v.23 no.4
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• pp.445-452
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• 2017

This study intends to improve the structural details of the anchors in the conventional CFT column-to-foundation connection. To that goal, finite element analysis is conducted with various design variables (number and embedded length of deformed bars, number, aspect ratio, height ratio and thickness ratio of ribs) selected based upon the results of loading test and strength evaluation. The finite element analysis is performed using ABAQUS and the analytical results are validated by comparison with the load-displacement curves obtained through loading test applying axial and transverse loads. The behavioral characteristics of the numerical model according to the selected design variables are verified and the corresponding results are evaluated.

• Journal of Microbiology and Biotechnology
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• v.32 no.5
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• pp.541-550
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• 2022

Filamentous marine fungi have proven to be a plentiful source of new natural products. Chaetomium, a widely distributed fungal genus in the marine environment, has gained much interest within the scientific community. In the last 20 years, many potential secondary metabolites have been detected from marine-derived Chaetomium. In this review, we attempt to provide a comprehensive summary of the natural products produced by marine-derived Chaetomium species. A total of 122 secondary metabolites that were described from 2001 to 2021 are covered. The structural diversity of the compounds, along with details of the sources and relevant biological properties are also provided, while the relationships between structures and their bioactivities are discussed. It is our expectation that this review will be of benefit to drug development and innovation.

• Molecules and Cells
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• v.46 no.12
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• pp.736-742
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• 2023

NifB, a radical S-adenosylmethionine (SAM) enzyme, is pivotal in the biosynthesis of the iron-molybdenum cofactor (FeMo-co), commonly referred to as the M-cluster. This cofactor, located within the active site of nitrogenase, is essential for the conversion of dinitrogen (N₂) to NH₃. Recognized as the most intricate metallocluster in nature, FeMo-co biosynthesis involves multiple proteins and a sequence of steps. Of particular significance, NifB directs the fusion of two [Fe₄S₄] clusters to assemble the 8Fe core, while also incorporating an interstitial carbide. Although NifB has been extensively studied, its molecular mechanisms remain elusive. In this review, we explore recent structural analyses of NifB and provide a comprehensive overview of the established catalytic mechanisms. We propose prospective directions for future research, emphasizing the relevance to biochemistry, agriculture, and environmental science. The goal of this review is to lay a solid foundation for future endeavors aimed at elucidating the atomic details of FeMo-co biosynthesis.

• Ocean Systems Engineering
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• v.3 no.1
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• pp.35-53
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• 2013

In this study, a hybrid floating structure with cylinder was introduced to reduce the hydrodynamic motions of the pontoon type. The hybrid floating structure is composed of cylinders and semi-opened side sections to penetrate the wave impact energy. In order to exactly investigate the hydrodynamic motions and structural behavior of the hybrid floating structure under the wave loadings, integrated analysis of hydrodynamic and structural behavior were carried out on the hybrid floating structure. Firstly, the hydrodynamic analyses were performed on the hybrid and pontoon models. Then, the wave-induced hydrodynamic pressures resulting from hydrodynamic analysis were directly mapped to the structural analysis model. And, finally, the structural analyses were carried out on the hybrid and pontoon models. As a result of this study, it was learned that the hybrid model of this study was showed to have more favorable hydrodynamic motions than the pontoon model. The surge motion was indicated even smaller motion at all over wave periods from 4.0 to 10.0 sec, and the heave and pitch motions indicated smaller motions beyond its wave period of 6.5 sec. However, the hybrid model was shown more unfavorable structural behavior than the pontoon model. High concentrated stress occurred at the bottom slab of the bow and stern part where the cylinder wall was connected to the bottom slab. Also, the hybrid model behaved with the elastic body motion due to weak stiffness of floating body and caused a large stress variation at the pure slab section between the cylinder walls. Hence, in order to overcome these problems, some alternatives which could be easily obtained from the simple modification of structural details were proposed.