• Structural Engineering and Mechanics
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• v.81 no.5
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• pp.647-664
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• 2022

The powerful data mapping capability of computational deep learning methods has been recently explored in academic works to develop strategies for structural health monitoring through appropriate characterization of dynamic responses. In many cases, these studies concern laboratory prototypes and finite element models to validate the proposed methodologies. Therefore, the present work aims to investigate the capability of a deep learning algorithm called Sparse Autoencoder (SAE) specifically focused on detecting structural alterations in real-case studies. The idea is to characterize the dynamic responses via SAE models and, subsequently, to detect the onset of abnormal behavior through the Shewhart T control chart, calculated with SAE extracted features. The anomaly detection approach is exemplified using data from the Z24 bridge, a classical benchmark, and data from the continuous monitoring of the San Vittore bell-tower, Italy. In both cases, the influence of temperature is also evaluated. The proposed approach achieved good performance, detecting structural changes even under temperature variations.

• Journal of the Korean Society for Library and Information Science
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• v.51 no.1
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• pp.227-243
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• 2017

This study proposed a structural and semantic framework for the characterization of events and segments in Web videos that permits content-based searches and dynamic video summarization. Although MPEG-7 supports multimedia structural and semantic descriptions, it is not currently suitable for describing multimedia content on the Web. Thus, the proposed metadata framework that was designed considering Web environments provides a thorough yet simple way to describe Web video contents. Precisely, the metadata framework was constructed on the basis of Chatman's narrative theory, three multimedia metadata formats (PBCore, MPEG-7, and TV-Anytime), and social metadata. It consists of event information, eventGroup information, segment information, and video (program) information. This study also discusses how to automatically extract metadata elements including structural and semantic metadata elements from Web videos.

• Journal of Microbiology
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• v.33 no.2
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• pp.126-127
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• 1995

A Zymomonas mobilis DNA fragment consisting of 207 nucleotides, which corresponded to the 5'-flanking region of an adhB gene encoding alcohol dehydrogenase II, was fused to the structural gene coding for a Bacillus endo-.betha.--1, 4-glucanase. The Z. mobilis DNA framgment waw identified to promote 50-fold increase in the expression of endo-.betha.1. 4 glucanase gene in Escherichia coli.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1998.11a
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• pp.81-84
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• 1998

New diagnostic techniques have been tried on the applications of chemical, physical and micro-structural methods because there was a limit to diagnose degradation in Korean Underground Residential Distribution (URD) power cables with the conventional electrical methods. In this study, non-electrical properties were carried out as such. Characterization of interface layer was analyzed by X-ray, characterization of insulator by water tree, degree of crosslinking, shrinkage as well as ${\mu}$ -FTIR, characterization of semiconductive layer by volume resistivity. Electrical properties were also performed by leakage current.

• Structural Engineering and Mechanics
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• v.70 no.2
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• pp.209-219
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• 2019

By normalizing the internal hysteresis variable and eliminating the redundant parameter, the normalized Bouc-Wen model is considered to be an improved and more reasonable form of the Bouc-Wen model. In order to facilitate application and further research of the normalized Bouc-Wen model, some key aspects of the model need to be uncovered. In this paper, hysteresis characterization of the normalized Bouc-Wen model is first studied with respect to the model parameters, which reveals the influence of each model parameter to the shape of the hysteresis loops. The parameter identification scheme is then proposed based on an improved genetic algorithm (IGA), and verified by experimental test data. It is proved that the proposed method can be an efficacious tool for identification of the model parameters by matching the reconstructed hysteresis loops with the target hysteresis loops. Meanwhile, the IGA is shown to outperform the standard GA. Finally, a simplified identification method is proposed based on parameter sensitivity, which indicates that the efficiency of the identification process can be greatly enhanced while maintaining comparable accuracy if the low-sensitivity parameters are reasonably restricted to narrower ranges.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1997.04a
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• pp.130-134
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• 1997

The structural defects, impurities, degree of crosslinking and shrinkage of 38 field-aged distribution cables have been analyzed. For the comparison of data, 9 new cables were also subjected to an analysis. It is observed that the structural defects and degree of crosslinking show a radial profile. The structural defects are different depending on the manufacturer. A large amount of impurities is present in the insulation shield, which hold true for the new cables manufactured recently. The degree of crosslinking near both shields is lower than that at the central region of the insulation layer. It was also found that, in some cal)toes, the ins난lation was not fully crosslinked. The shrinkage of field-aged cables is higher than that of new cables.

• Molecules and Cells
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• v.42 no.7
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• pp.512-522
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• 2019

Chromosomes located in the nucleus form discrete units of genetic material composed of DNA and protein complexes. The genetic information is encoded in linear DNA sequences, but its interpretation requires an understanding of three-dimensional (3D) structure of the chromosome, in which distant DNA sequences can be juxtaposed by highly condensed chromatin packing in the space of nucleus to precisely control gene expression. Recent technological innovations in exploring higher-order chromatin structure have uncovered organizational principles of the 3D genome and its various biological implications. Very recently, it has been reported that large-scale genomic variations may disrupt higher-order chromatin organization and as a consequence, greatly contribute to disease-specific gene regulation for a range of human diseases. Here, we review recent developments in studying the effect of structural variation in gene regulation, and the detection and the interpretation of structural variations in the context of 3D chromatin structure.

• Korean Journal of Materials Research
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• v.25 no.1
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• pp.1-8
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• 2015

This study suggested comprehensive structural characterization methods for the commercial blue light emitting diodes(LEDs). By using the Z-contrast intensity profile of Cs-corrected high-angle annular dark field scanning transmission electron microscope(HAADF-STEM) images from a commercial lateral GaN-based blue light emitting diode, we obtained important structural information on the epilayer structure of the LED, which would have been difficult to obtain by conventional analysis. This method was simple but very powerful to obtain structural and chemical information on epi-structures in a nanometer-scale resolution. One of the examples was that we could determine whether the barrier in the multi-quantum well(MQW) was GaN or InGaN. Plan-view TEM observations were performed from the commercial blue LED to characterize the threading dislocations(TDs) and the related V-pit defects. Each TD observed in the region with the total LED epilayer structure including the MQW showed V-pit defects for almost of TDs independent of the TD types: edge-, screw-, mixed TDs. The total TD density from the region with the total LED epilayer structure including the MQW was about $3.6{\times}10^8cm^{-2}$ with a relative ratio of Edge- : Screw- :Mixed-TD portion as 80%: 7%: 13%. However, in the mesa-etched region without the MQW total TD density was about $2.5{\times}10^8cm^{-2}$ with a relative ratio of Edge- : Screw- :Mixed-TD portion of 86%: 5%: 9 %. The higher TD density in the total LED epilayer structure implied new generation of TDs mostly from the MQW region.

• Molecules and Cells
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• v.22 no.1
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• pp.13-20
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• 2006

Hepatitis C virus (HCV) non-structural protein 5A protein (NS5A), which consists of three functional domains, is involved in regulating viral replication, interferon resistance, and apoptosis. Recently, the three-dimensional structure of the domain 1 was determined. However, currently the molecular basis for the domains 2 and 3 of HCV NS5A is yet to be defined. Toward this end, we expressed, purified the domain 2 of the NS5A (NS5A-D2), and then performed biochemical and structural studies. The purified domain 2 was active and was able to bind NS5B and PKR, biological partners of NS5A. The results from gel filtration, CD analysis, 1D $^1H$ NMR and 2D $^1H-^{15}N$ heteronuclear single quantum correlation (HSQC) spectroscopy indicate that the domain 2 of NS5A appears to be flexible and disordered.

• Journal of the Korean Chemical Society
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• v.47 no.4
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• pp.427-431
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• 2003