• Current Research on Agriculture and Life Sciences
• /
• v.1
• /
• pp.201-214
• /
• 1983

A study was undertaken on rats in order to clarify the gastric mucosal, morphologic response to oral and subcutaneous administration of acetylsalicylic acid(aspirin). Aspirin was administered orally (oral group) and subcutaneously (subcutaneous group) at does rate of 60 mg per kg of body weight per day to 40 normal rats. On the 1st, 3rd, 7th, and 15th day of administration, in addition to clinical observation, 5 rats each from the both groups were sacrificed and examined macroscopically, histologically and electron-microscopically for the morphological changes of gastric mucosal cells with the following results. Although the clinical, macroscopic and histological changes were not significant, marked ultrastructural changes were observed. Parietal and chief cells were affected most severely by the administration of aspirin ; parietal cells showed increase in the number of SER and intracellular canaliculi, where-as in chief cells fragmentation, luminal dilatation, decrease in the number and structural abnormalities of RER were seen. Relatively mild changes were observed in mucous, mucous neck and basal-granulated cells. Although the degree of changes was milder than those of oral group, the similar changes were also observed in the subcutaneous group. From these results, it would be concluded that aspirin injury of gastric mucosa is effected not only by the direct injury to the mucosa but also indirectly by the blood concentration of aspirin.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.21 no.6
• /
• pp.317-324
• /
• 2020

In this study, a simplified equation for settlement evaluation suitable for the special conditions of a counter facility is suggested. Recently, counter facilities, especially breakwaters, are constructed on soft ground in distant seas as new-port development projects. A counter facility that resists the external forces by self-weight settles easily when constructed on soft ground. Settlement in a counter facility and breakwater is not an important factor for maintenance than a land facility. On the other hand, the current settlement evaluation criteria are excessive for conducting a safety inspection. A settlement evaluation from a safety inspection followed by "Detailed Guidelines for a safety inspection on a counter facility" is used. A simplified equation was proposed to calculate the maximum settlement by applying the allowable residual settlement or settlement stability evaluation results. The suitability of the simplified equation was assessed compared to the assessed rating from the settlement survey results. The proposed simplified equation showed that the settlement evaluation rating had been upgraded. The proposed simplified equation is expected to be used to evaluate the practical structural stability and functional performance.

• Journal of the Microelectronics and Packaging Society
• /
• v.24 no.4
• /
• pp.39-46
• /
• 2017

This paper presents the fabrication of ceramic insulation layer on metallic heat spreading substrate, i.e. an insulated metal substrate, for planar type heater. Aluminum alloy substrate is preferred as a heat spreading panel due to its high thermal conductivity, machinability and the light weight for the planar type heater which is used at the thermal treatment process of semiconductor device and display component manufacturing. An insulating layer made of ceramic dielectric film that is stable at high temperature has to be coated on the metallic substrate to form a heating element circuit. Two technical issues are raised at the forming of ceramic insulation layer on the metallic substrate; one is delamination and crack between metal and ceramic interface due to their large differences in thermal expansion coefficient, and the other is electrical breakdown due to intrinsic weakness in dielectric or structural defects. In this work, to overcome those problem, selected metal oxide buffer layers were introduced between metal and ceramic layer for mechanical matching, enhancing the adhesion strength, and multi-coating method was applied to improve the film quality and the dielectric breakdown property.

• Journal of the Korea Concrete Institute
• /
• v.18 no.1 s.91
• /
• pp.57-64
• /
• 2006

The crack presented in concrete structures causes a structural defect, the durability decrease, and external damages etc. Therefore, it is necessary to improve durability through the effort to control the crack. Fluosilicic acid($H_2SiF_6$) is recovered as aqueous solution which absorbs $SiF_4$ produced from the manufacturing of industrial-graded $H_3PO_4$ or HF. Generally, fluosilicates prepared by the reaction between $H_2SiF_6$ and metal salts. Addition of fluosilicates to cement endows odd properties through unique chemical reaction with the fresh and hardened cement. Mix proportions for experiment were modulated at 0.45 of water to cement ratio and $0.0{\sim}2.0%$ of adding ratio of fluosilicate salt based inorganic compound. To evaluate correlation of concrete strength and adding ratio of fluosilicate salt based inorganic compound, the tests were performed about design strength(21, 24, 27 MPa) with 0.5% of adding ratio of fluosilicate salt based inorganic compound. Applications of fluosilicate salt based inorganic compound to reduce cracks resulted from plastic and drying shrinkage, to improve durability are presented in this paper. Durability was evaluated as neutralization, chloride ion penetration depth, freezing thawing resistant tests and weight loss according reinforcement corrosion. It is ascertained that the concrete added fluosilicate salt based inorganic compound showed m ability to reduce the total area and maximum crack width significantly as compared non-added concrete. In addition, the durability of concrete improved because of resistance to crack and watertightness by packing role of fluosilicate salt based inorganic compound obtained and pozzolanic reaction of soluble $SiO_2$ than non-added concrete.

• Journal of the Korea Concrete Institute
• /
• v.19 no.6
• /
• pp.717-726
• /
• 2007

If conventional reinforcements are used for high-strength concrete (HSC) structures, a large amount of the reinforcement must be required to compensate for the brittleness of HSC and make the best use of HSC. This raises some structural problems such as steel congestion and an increase in self-weight. Therefore, alternative reinforcing materials and methods for HSC structures are needed. In this study, four full-scale beam specimens constructed with HSC (100 MPa) were tested to investigate the effect of the different shear reinforcements on the shear behavior. These four specimens were reinforced for shear stirrups with normal and high strength steels, headed bars, and carbon fiber-reinforced polymer (CFRP) bars, respectively. In addition, steel fibers were added to the HSC in the two of the specimens to observe their beneficial effects. The use of high strength steels resulted in the improvement of the shear capacity since the shear resistance provided by the shear reinforcements and the bond strength were increased. The specimen reinforced with headed bars also showed a superior performance to the conventional steel reinforced specimen due to the considerably high anchorage strength of headed bar. CFRP bars used in this research, however, seemed to be inadequate for shear reinforcement because of the inferior bond capacity. The presence of the steel fibers in concrete led to remarkable improvement in the ductility of the specimens as well as in the overall cracks control capability.

• Journal of Korean Academy of Nursing
• /
• v.10 no.2
• /
• pp.73-85
• /
• 1980

The purpose of this study was to investigate the compliance behavior of hypertensive patients in light of their health belief model that explains an individual's compliance with health maintenance or getting well. Although there are many effective regimens and treatments for hypertension nowadays. the most important point to be taken to consideration in their behavioral aspect is their compliance with regard to the control of body weight. eating habits as to salt and cholesterol intake. stresses. activity patterns and smoking as related to their life style. The important reasons for the failure in the control of hypertensive patients are the complexity of regimens to be complied to. irregular medication and the life long restrictions in their own life style. The compliance of patients to medical regimens and rocommendations or failure to do so is an essential factor. Accordingly. the degree of the patient's compliance is an important determinant as to the success or failure of hypertension control. The subjects for this study were 187 hypertensive patients selected from admitted and out patients of the medical department at seven University Hospitals in Seoul. Data was collected from Dec. 1, 1979 to Feb. 15, 1980 using the questionaire method and was analysed by the use of means. standard deviations, coefficient of correlations, analysis of variance and multiple regression analysis. The results obtained are as follows A. Of the seven independent variables in light of health belief model. benefit. barrier and severity are closely related to patient's compliance behavior. Therefore these variables could be used as determinants to predict and modify the hypertensive behavior. 1. Benefit is the most important and significant of the variables for explaining the dependent variables. It accounts for the highest variance of patient's compliance. (23.62%) 2. Then taking the former together with barrier. the variance of compliance showed on increase. (26.59%) 3. And with the addition of severity to the first two. the variance of compliance was also increased. (28.l2 %) B. Except for susceptibility all the independent variables such as severity. benefit, knowledge. motivation and barrier are correlated to dependent variable compliance. C. Sex. marital status and religion appeared to have significant influence on the dependent variables. Therefore one could conclude that the more the patients are aware that hypertension is a threat to health. the more they understand the benefit of taking actions to prevent such a threat. and the less they perceive any barrier when taking action. the more compliant they become in following medical regimens and recommendations. Age. marital status and religion played a significant influence to their compliance. Accordingly. the selected structural variables and demographic variables which have influenced sick role behavior of the hypertensive patient must be integrated to teaching and counselling programs for better hypertension control.

• Journal of the Korean Crystal Growth and Crystal Technology
• /
• v.30 no.4
• /
• pp.156-161
• /
• 2020

Recently, as there has been growing demand for aesthetic quality in structural materials, the development of excellent color cement concrete having good coloration properties has become a requirement. This study is designed to analyze the basic physical properties of mortar and the properties of keeping the coloration under an ultraviolet ray accelerated weathering test environment according to changes in the mixing ratio between carbon black and iron oxide used as colorants. The test results show that the use of carbon black and iron oxide reduces the initial flow by 6.3~17.2 % and the air content by 3.5~31.5 % but increases the unit volume weight by 3.4~5.5 %, compared to ordinary Portland cement (OPC). In addition, the study shows that the addition of iron oxide increases the self drying shrinkage. So, caution needs to be taken on the workability of the concrete. The brightness value L^⁎ represented by black showed the most excellent black colour when carbon black 3 % and iron oxide 5 % are added. According to UV accelerated weatherproof test, the brightness value L^⁎ was found to increase in all experiment specimens by 4.28~11.97 %, and the color change by UV was found to be higher for the case where carbon black colorant was not used. Therefore, in terms of color revelation characteristics, the case using carbon black 3 % and iron oxide 5 % was found to show the best black color.

• Korean Journal of Construction Engineering and Management
• /
• v.5 no.6 s.22
• /
• pp.212-217
• /
• 2004

Carbon fiber reinforced plastic(CFRP) plate Is one of the alterative materials for soengthening of reinforced and prestressed connote members due to excellent strength and light weight In this paper, the behavior of beams strengthened with CFRP plate and CFS(Carbon fiber sheet) is observed and analyzed from the test results. Especially specimens with thick plate is tested when large moment and large shear lone appear in same position. The main failure mode is a peeling-off of the CFRP plate near the loading points due to flexural-shear crack, Because of this failure mode, failure load is not linearly proportional to the thickness of CFRP plates. When beam is wrapped with CFS around oかy loading point it does not influence on the failure loads. Depending on the loading pattern, it is necessary to consider different design criteria for reinforced concrete members with external reinforcement. When line moment and large shear force appear in same location, maximum thickness may limit to 0.6mm and ratio between moment of strengthened beam and moment of unstrengthened beam is proposed 1.5-2.0. In order to use the plate of thicker than 6mm, CFS may be extended to the location which moment of strengthened beam is 1.5 times than moment of unstrengthened beam.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.37 no.7
• /
• pp.834-840
• /
• 2008

In order to improve the use of pumpkin seed, the present study was performed to isolate compositions of the bitter components which were not seen in pumpkin seed itself but newly biosynthesized during germination of the seed. The compositions isolated were then further purified by TLC and preparative HPLC in which a fraction with Rf 0.73 and RT 10.3 was obtained. Cucurbitacin E with molecular weight of 557 from the fraction was finally identified by subsequent structural analysis of LC-MS/MS. The production of cucurbitacin E peaked with 224.7 mg/kg at 4 days of germination at $20^{\circ}C$ with the water supply at ntervals of 48 hrs in the darkness, while that of cucurbitacin E reached 146.7 mg/kg in the brightness. In vitro-cell based assays demonstrated that the isolated and purified cucurbitacin E inhibited proliferation of A549 lung cancer cells and suppressed expression of the IL-$1{\beta}$- or PMA-induced cyclooxygenase-2, an inflammatory protein in A549 cells, suggesting its anti-proliferative and anti-inflammatory activities.

• Composites Research
• /
• v.16 no.4
• /
• pp.66-73
• /
• 2003

The importance of understanding the response of structural composites to impact and CAI cannot be overstated to develop analytical models for impact damage and CAI strength predictions. This paper presents experimental findings observed from quasi-static lateral load tests, low velocity impact tests. CAI strength and open hole compressive strength tests using 3 mm thick composite plates($[45/-45/0/90]_{3s}$- IM7/8552). The conclusion is drawn that damage areas for both quasi-static lateral load and impact tests are similar and the curves of several drop weight impacts with varying energy levels(between 5.4 J and 18.7 J) follow the static curve well. In addition, at a given energy the peak force is in good agreement between the static and impact cases. It is identified that the failure behaviour of the specimens from the CAI strength tests was very similar to that observed in laminated plates with open holes under compression loading. The residual strengths art: in good agreement with the measured open hole compressive strengths. considering the impact damage site area, an equivalent hole. The experimental findings suggest that simple analytical models for the prediction of impact damage area and CAI strength can be developed on the basis of the failure mechanism observed from the experimental tests.