• 한국전자거래학회지
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• 제20권2호
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• pp.125-140
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• 2015

공급사슬에서 발생한 위험의 영향력은 위험이 발생한 영역에만 국한되는 것이 아니라 연결구조를 따라 네트워크 전체에 퍼지게 된다. 이러한 위험의 전파 현상으로 인해 공급사슬은 네트워크 연결 구조에 의해 위험의 영향을 받게 될 가능성이 달라진다. 따라서 공급사슬 네트워크를 설계하는 시점에 구조적 연결성을 고려하여 내외부 위험의 발생에 따른 비용을 최소화할 수 있어야 한다. 일반적으로 매개 중심성은 위험의 발생가능성과 영향력의 확산을 설명하는 지표로 해석할 수 있다. 본 연구에서는 구조적 취약성 관점에서의 재해석과 수정을 통해 서로 다른 공급사슬의 취약성을 정량적으로 비교하고, 보다 안정적인 네트워크 구조를 선택할 수 있는 방안을 제시한다.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2003년도 제2차 연례학술대회 발표논문집
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• pp.26-51
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• 2003

Large scale protein interaction maps provide a new, global perspective with which to analyse protein function. PSIMAP, the Protein Structural Interactome Map, is a database of all the structurally observed interactions between superfamilies of protein domains with known three-dimensional structure in thePDB. PSIMAP incorporates both functional and evolutionary information into a single network. It makes it possible to age protein domains in terms of taxonomic diversity, interaction and function. One consequence of it is to predict the most important protein domain structure in evolution. We present a global analysis of PSIMAP using several distinct network measures relating to centrality, interactivity, fault-tolerance, and taxonomic diversity. We found the following results: ${\bullet}$ Centrality: we show that the center and barycenter of PSIMAP do not coincide, and that the superfamilies forming the barycenter relate to very general functions, while those constituting the center relate to enzymatic activity. ${\bullet}$ Interactivity: we identify the P-loop and immunoglobulin superfamilies as the most highly interactive. We successfully use connectivity and cluster index, which characterise the connectivity of a superfamily's neighbourhood, to discover superfamilies of complex I and II. This is particularly significant as the structure of complex I is not yet solved. ${\bullet}$ Taxonomic diversity: we found that highly interactive superfamilies are in general taxonomically very diverse and are thus amongst the oldest. This led to the prediction of the oldest and most important protein domain in evolution of lift. ${\bullet}$ Fault-tolerance: we found that the network is very robust as for the majority of superfamilies removal from the network will not break up the network. Overall, we can single out the P-loop containing nucleotide triphosphate hydrolases superfamily as it is the most highly connected and has the highest taxonomic diversity. In addition, this superfamily has the highest interaction rank, is the barycenter of the network (it has the shortest average path to every other superfamily in the network), and is an articulation vertex, whose removal will disconnect the network. More generally, we conclude that the graph-theoretic and taxonomic analysis of PSIMAP is an important step towards the understanding of protein function and could be an important tool for tracing the evolution of life at the molecular level.

• 한국전산구조공학회논문집
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• 제20권3호
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• pp.321-327
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• 2007

본 연구는 탄성균열문제를 신속하고 정확하게 해석할 수 있는 새로운 개념의 그리드(grid) 없는 유한차분법을 제시한다. 이동최소제곱법을 이용한 Taylor 전개식 구성을 통해 직접적인 미분계산 없이 근사함수와 그 미분을 손쉽게 계산한다. 그리드로 인한 절점 간의 종속성이 없어 해석영역 내의 불연속면 모델링이 용이하여 차분식 구성시 균열로 인한 불연속 효과를 고려하는 과정도 자연스럽다. 유한차분법에 근간을 두고 있어 지배 미분방정식을 직접 이산화하기 때문에 수치적분이 필요한 수치기법에 비해 계산속도도 빠르다. 모드 I과 모드 II 균열문제 해석을 통해 본 해석기법이 정확하고 효율적으로 응력확대계수를 계산할 수 있음을 보였다.

• 생물정신의학
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• 제21권1호
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• pp.1-13
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• 2014

Normal aging causes changes in the brain volume, connection, function and cognition. The brain changes with increases in age and difference of gender varies at all levels. Studies about normal brain aging using various brain magnetic resonance imaging (MRI) variables such as gray and white matter structural imaging, proton spectroscopy, apparent diffusion coefficient, diffusion tensor imaging and functional MRI are reviewed. Total volume of brain increases after birth but decreases after 9 years old. During adulthood, total volume of brain is relatively stable. After 35 years old, brain shrinks gradually. The changes of gray and white matters by aging show different features. N-acetylaspartate decreases or remains unchanged but choline, creatine and myo-inositol increase with aging. Apparent diffusion coefficient decreases till 20 years old and then becomes stable during adulthood and increase after 60 years old. Diffusion tensor properties in white matter tissue are variable during aging. Resting-state functional connectivity decreases after middle age. Structural and functional brain changes with normal aging are important for studying various psychiatric diseases such as dementia, schizophrenia and bipolar disorder. Our review may be helpful for studying longitudinal changes of these diseases and successful aging.

• 한국전산구조공학회논문집
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• 제27권3호
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• pp.183-189
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• 2014

본 연구에서는 다면체 요소의 개발을 위하여 Wachspress 좌표계와 이동최소자승 근사를 기반으로하는 형상함수와 수치적분 방법을 제시하고 있다. 사면체 요소를 사면체 영역으로 분할하여 형상함수가 구성이 되고 이 영역을 사용한 일관성있는 수치적분이 수행되게 된다. 다면체 요소 면에서 Wachspress 좌표계를 사용하고 요소 내부에서 라플라스 방정식을 적용하여 이동최소자승 근사의 가중함수를 정의하게 된다. 본 연구에서 개발되는 다면체 요소의 형상함수와 수치적분 방법은 일반적인 유한요소와 유사한 특성을 갖게 되는데 수치 예제를 통하여 유효성을 보여주었다.

• 복식문화연구
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• 제23권2호
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• pp.228-241
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• 2015

The purpose of this study was to verify the effect of mobile fashion shopping characteristics and perceived interactivity on perceived usefulness, and the effect of perceived usefulness on purchase attitude and purchase intention based on TAM (Technology Acceptance Model). We conducted the survey targeting smartphone users in their 20s~30s living in Seoul and metropolitan area. Among 483 data collected, we used 452 samples except 31 unreliable respondents for the analysis. To analyze the structural equation model, we did factor analysis, reliability analysis, and structural equation model analysis using SPSS 18.0 and AMOS 16.0. The results were as follows: We confirmed 5 mobile fashion shopping characteristics (enjoyment, credibility, instant connectivity, security, and personalization) and 3 perceived interactivity factors (control, responsiveness and two-way communication, and contextual offer) as results of confirmative factor analysis. Mobile fashion shopping characteristics and perceived interactivity had positive effects on perceived usefulness. Mobile fashion shopping characteristics affected perceived interactivity and also had indirect effect on perceived usefulness via perceived interactivity. In other words, mobile fashion shopping characteristics had direct and indirect effect on perceived usefulness. Perceived usefulness influenced purchase attitude and purchase attitude influenced purchase intention. Perceived usefulness had direct effect on purchase intention and the indirect effect through purchase attitude was significant.

• 한국농공학회논문집
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• 제64권5호
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• pp.67-77
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• 2022

Recently, the trend in structural analysis and design is moving towards the development of reliable system. The reliability-based method defines various limit states related to usability and failure, thereby enabling multiple levels of design according to the importance of a structure. Meanwhile, an actual structure is composed of a set of several elements, and particularly, a frame type is composed of a system in which the members are connected each other. At this time, the actual connection between members is in a semi-rigid condition, not in complete rigid or hinged. This semi-rigid is found in several structures, especially in agricultural facilities designed with lightweight materials. In this study, a system reliability analysis technique for frame structure was established, and applied to an analysis of the semi-rigid connection. Various conditions of correlation were applied to reflect the connectivity between members, and through this, the limitations of existing structural analysis method and the behavioral characteristics of structure were analyzed. The failure probability of the frame member component and the overall structure system was significantly different in consideration of the semi-rigid connection. In addition, it was evaluated that the behavior of structure can be more accurately analyzed if the correlation according to the position of members in a system is further investigated.

• 한국실내디자인학회논문집
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• 제25권6호
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• pp.3-14
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• 2016

According to Plato's ontology, we lead our lives by establishing a relationship with others in the society. However in rapidly changing era, our lives was gradually moving towards personal tendency. Even for the relationship with family, not with others. Thus, awareness about owning properties has changed due to the sociocultural factors and increase number of single-person households. So in this study, the considerations for single-person housing were perceived through preceding research, and the elements making spatial boundary of shared housing were drawn to make rational space sharing based on the boundary with others and of the living environment. With overall analysis based on the spatial boundary features of planned shared housing, the plan characteristics according to the spatial boundary of the current shared housing is to be drawn and analyzed. Third, The expressive and structural features of spatial boundary as above appear with mutual flexible connectivity, And the result shows that the modularity was the highest. Among them variable coupling modularity of shows how it is possible to combine efficiently and variously the private and public spaces with regularity of 'space of optimal unit'. This study drew plan characteristics from more detailed space border of shared housing. Therefore, The basic framework of the characteristics spin for the cases that newly emerge later on.

• BMB Reports
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• 제47권11호
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• pp.625-630
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• 2014

Defensins, which are small cationic molecules produced by organisms as part of their innate immune response, share a common structural scaffold that is stabilized by three disulfide bridges. Coprisin is a 43-amino acid defensin-like peptide from Copris tripartitus. Here, we report the intramolecular disulfide connectivity of cysteine-rich coprisin, and show that it is the same as in other insect defensins. The disulfide bond pairings of coprisin were determined by combining the enzymatic cleavage and mass analysis. We found that the loss of any single disulfide bond in coprisin eliminated all antibacterial, but not antifungal, activity. Circular dichroism (CD) analysis showed that two disulfide bonds, Cys20-Cys39 and Cys24-Cys41, stabilize coprisin's ${\alpha}$-helical region. Moreover, a BLAST search against UniProtKB database revealed that coprisin's ${\alpha}$-helical region is highly homologous to those of other insect defensins.

• 유통과학연구
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• 제16권7호
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• pp.57-65
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• 2018

Purpose - Recently, internet access and social network utilization using smart phone are increasing. In such a smart environment, interactive activities such as information generation, information searching and information sending are increasing rapidly on-line environment. Therefore, consumers tend to purchase something according to eWOM and also meet the social consensus online environment. In connectivity society, consumers became accessible and engaged in the opinions of others easily. Many decisions that seem like personal decisions are actually social decisions on online connectivity. This paper seeks to explore factors that can help generate a social decision on purchasing of new products in an online environment. Research design, data, and methodology - The process of collecting a lot of wisdom and making an agreement online is called social decision. The purpose of this paper is to examine empirically the influence of factors such as online ties, online eWOM expectancy and online information behavior on online social decision. In addition, We studied online social decision by analyzing the moderating effect of new product innovation. To understand this structural relationship, research hypotheses and research models were set up and empirical analysis was conducted. In order to verify the hypothesis, 208 questionnaires were collected from the residents of Seoul city/Gyeonggi province. The answered questionnaire verifies reliability and validity using SPSS/AMOS and test hypotheses through path analysis and multiple regression analysis. Results - According to the research results, First, online ties don't have a positive impact on online social decision, Second, online eWOM expectancy have a positive impact on online social decision. Third, online information behaviors have a positive impact on online social decision. The degree of innovation of new products have a moderating effect between Independent variables of three factors and dependent variable of social decision. Conclusions - Social decisions have a positive impact on purchasing decisions about new product. There is a great significance in the fact that the online social influence and online social decision have been studied academically. It is meaningful that we have studied in depth the changing phenomenon of consumer purchase decision process in smart environment. The results of these studies provide academic and practical implications.