• 제목/요약/키워드: Stroma

검색결과 330건 처리시간 0.028초

악하선 부위에 발생한 편평세포암종 (Squamous cell carcinoma in the submandibular space)

  • 안병모;이삼선;허민석;최현배;최순철
    • Imaging Science in Dentistry
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    • 제31권2호
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    • pp.117-120
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    • 2001
  • A 66-year-old man visited author's institute complaining of the swelling on the submandibular gland area. Clinically, the exophytic mass penetrated the skin of the submandibular area. On MRI, the lesion occupied the left submandibular space and extended downward, protruding exterior to the subcutaneous fat layer, but the center of the lesion was located on the side of the skin and the growth exterior to the skin was prominent. Demarcation of the lesion and the submandibular gland was unclear. Histopathologically the epithelial nests and keratin production were seen, then the biopsy result was squamous cell carcinoma. The stroma of lesion showed a myxoid characteristic and some ducts showed metaplasia of the ductal cells, which suggested the gland-origin carcinoma. However, lots of keratin production and carcinomatous change of cells continuous to the normal epithelium of the skin, the skin-origin carcinoma invading into the submandibular gland area could not be excluded.

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소아 Lipoblastoma의 임상 양상 (The Clinical Manifestations of Lipoblastoma in Children)

  • 남소현;김대연;김성철;김인구
    • Advances in pediatric surgery
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    • 제13권2호
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    • pp.179-186
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    • 2007
  • Lipoblastoma is a rare benign soft tissue tumor occurring in infancy and early childhood. It is characterized by fat lobules with varying degrees of maturity, multivaculoated lipoblasts, fibrocapillary networks and myxoid stroma. Lipoblastoma has a good prognosis with no metastases despite its potential for local invasion. From Jan, 1990 through April, 2007, 12 children underwent the operation for lipoblastoma, 7 boys and 5 girls, diagnosed at median 22 months (5 ~ 43 months). Median follow up was 6 year 7 months. Primary sites included back (n = 5), intraabdominal (n = 2) and one in each of buttock, chest wall, neck, nose and scalp. Tumors presented with a growing mass in 9 patients, abdominal distension in 2, and an incidental finding on chest radiography in one. Complete excisions were done in all patients. There was one recurrence in a patient with a scalp mass. After reoperation, he has been doing well without evidence of recurrence. Lipoblastoma has a favorable prognosis, but recurrence can occur even with complete excision. Regular follow up is necessary to detect recurrences.

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다형성 선종에서 발생한 구개부의 상피성-근상피암종 (EPITHELIAL-MYOEPITHELIAL CARCINOMA ARISING IN PLEOMORPHIC ADENOMA OF PALATE)

  • 김경욱;한세진
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제33권5호
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    • pp.479-484
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    • 2007
  • 본 교실에서는 상악 구개부의 무통성 종창을 주소로 내원한 다형성 선종의 병력을 가진 환자에 대한 임상적, 조직병리학적, 면역병리학적 검사들을 통하여 최종적으로, 드물게 발병하는 다형성 선종 유래 악성 상피성-근상피암종으로 진단하였으며, 상악골 부분 절제술 및 측두근 피판 지연 재건술 시행 후 현재까지 재발의 소견 없이 양호한 치료 결과를 얻었기에 보고하는 바이다.

비강 및 부비동에 발생한 거대란 반전성유두종 1예 (A Case of the Inverted Papilloma of the Nose and Paranasal Sinuses)

  • 김정래;권평중;김중환
    • 대한기관식도과학회:학술대회논문집
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    • 대한기관식도과학회 1981년도 제15차 학술대회연제순서 및 초록
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    • pp.12.4-12
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    • 1981
  • 비강 및 부비동에 발생하는 반전성유두종은 극히 드문 양성종양으로 1854년 Ward가 처음으로 보고하였으며 이후 여러학자들에 의하여 본증이 논의되어왔으나 우리나라에서는 그 보고례가 몇례 없었다. 비강 및 부비동에 발생하는 반전성유두종은 진성종양으로 비용과 현저히 다르며 제거후에도 재발하는 경우가 많고 드물긴 하지만 악성으로 변하는 경우가 있다. 일단 반전성유두종으로 밝혀지게 되면 가능한 한 광범위하게 제거해줘야되며 계속적인 추적조사가 필요하다. 최근 저자들은 비출혈, 비폐색, 취각장애, 두통을 주소로 내원한 64세된 여자환자에서 좌측 상악등에 압박괴사를 초래한 반전성유두종 1례를 치험하였기에 문헌고찰과 아울러 보고하는 바이다.

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Intrathoracic Desmoid Tumor Mimicking Pleural Mass: A Case Report

  • Kim, Na Rae;Chung, Dong-Hae;Lee, Jae-Ik;Jeong, Sung Hwan;Ha, Seung-Yeon
    • Tuberculosis and Respiratory Diseases
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    • 제67권5호
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    • pp.449-453
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    • 2009
  • Desmoid tumor (fibromatosis) is a histologically benign fibrous neoplasm showing locally infiltrating growth. This type of tumor commonly occurs in the abdomen, but intrathoracic desmoid tumor is uncommon. To date, 12 cases of intrathoracic desmoid tumor protruding into the pleural cavity, radiologically mimicking pleural masses, have been reported. Here, we report on a case of intrathoracic desmoid tumor protruding into the pleural cavity, and partially covered by parietal pleura. The main preoperative differential diagnoses included pleural solitary fibrous tumor, inflammatory pseudotumor or malignant mesothelioma. A near-total mass excision was performed. Pathologically, the tumor was composed of a paucicellular arrangement of spindle-shaped cells with fibromyxoid stroma. The resection margin was partially involved with spindle cells present. On histochemical staining, the spindle cells were strongly positive for vimentin and negative for CD34, consistent with a desmoid tumor. The patient was stable without further adjuvant treatment during 6-years of follow-up.

구강암의 조직비반세포에 관한 연구

  • 전동진
    • 대한치과의사협회지
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    • 제12권1호
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    • pp.21-28
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    • 1974
  • The author has observed the distribution of the tissue mast cells in 67 various tumors and precancerous lesions which occurred in the oral cavity. The specimcns ware obtained from the department of oral pathology, college of dentistry, Seoul National University, from Jan. 1970 to June, 1973. The results are as follows: 1) The number of the tissue mast cell was decrease predominantly in malignant tumors, especially in squamous cell carcinomas and in sarcomas. 2) The number of the tissue mast cell distirbution in adenocarcinomas one of malignant group was sligtly increased in with healthy oral mucosa. 3) The number of tissue mast cells in ameloblastomas one of benign group of the tumor of epithelial originwas more decreased than that in healthy oral mucosa. 4) The number of tissue mast cells in fibromas was more than that in healthy oral mucosa. 5) The number of the tissue mast cells in mixed tumors was increased one and a half times as many as that in healthy oral mucosa. 6) The number of the tissue mast cells in mixed tumors was increased one and a half times as many as that in healthy oral mucosa. 7) The tissue mast cell distribution can be observed more densly in the stroma of tumors than in the parenchyme of tumors.

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이하선의 기저세포선암 (Basal Cell Adenocarcinoma of the Parotid Gland)

  • 이준호;정웅윤;박정수
    • 대한두경부종양학회지
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    • 제13권1호
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    • pp.81-85
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    • 1997
  • Basal cell adenocarcinoma is a rare, recently described neoplasm of the salivary gland. We have experienced three cases of basal cell adenocarcinoma of the parotid gland. The tumors from patient 1 and patient 2 showed intraparotid growth in superficial lobe without cervical lymphnode metastasis. So, patient 1 and patient 2 underwent only a superficial parotidectomy and subdigastric lymphnode dissection without any adjuvant therapy. They are alive without recurrence or distant metastasis. But that of patient 3 showed widely invasive growth with multiple cervical lymph node metastases. The CT scan showed a $8{\times}7cm$ sized huge mass replacing the parotid gland with irregular margin and multiple lymphnode enlargements along the internal jugular vein. Total parotidectomy with sacrifying the facial nerve and standard radical neck dissection were caried out. Microscopically, the tumor consisted of solid nest and sheet of uniform basaloid cells separated by a fibrous connective tissue stroma with the evidence of lymphovascular invasion. As a result of the lymphnode metastasis and invasiveness of the tumor, radiation therapy was given postoperatively. We thought that close follow-up would be mandatory in this patient because of high risk of possible local recurrence and distant metastasis.

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Desmoplastic Small Round Cell Tumor : A Case Report

  • Choi, Joon-Hyuk;Yun, Sung-Soo;Chang, Jay-Chun
    • Journal of Yeungnam Medical Science
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    • 제23권1호
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    • pp.90-95
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    • 2006
  • 결합조직형성소원형세포종양은 매우 드문 악성 연부조직 종양으로 소아와 청소년기에 복강과 골반강 내에 주로 발생한다. 저자들은 복강에 발생한 결합조직형성소원형세포종양 1예를 경험하였기에 문헌 고찰과 함께 보고한다. 50세 남자가 2개월간의 복부 불쾌를 주소로 내원하였다. 방사선 소견에서 오른쪽 복강 내에 종괴가 관찰되었다. 절제된 종괴는 크기가 $14.0{\times}12.5{\times}8.5cm$ 이며, 회백색을 띠었으며 가로 잘록창자의 장막에 붙어 있었다. 조직학적으로 종괴는 결합조직을 형성하는 기질 내에 작고 둥근 핵을 가진 종양세포들의 증식이 보였다.

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Desmoplastic Fibroblastoma of the Scalp Accompanied by Severe Pain; Unusual Location and Symptom

  • Yang, Ji Hoon;Chae, Je-Byeong;Huh, Chang-Hun;Na, Jung-Im;Park, Kyoung-Chan;Shin, Jung-Won
    • Annals of dermatology
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    • 제30권6호
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    • pp.712-715
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    • 2018
  • Desmoplastic fibroblastoma is a rare fibrous tumor that usually presents as a painless, slow-growing mass in the subcutaneous tissues and skeletal muscles. It has a wide anatomic distribution, with the most common involvement being the arm and shoulder. Here, we report a case of a tiny painful desmoplastic fibroblastoma arising on the scalp. According to a microscopic examination, this tumor was composed of spindle-shaped fibroblasts in the dense collagenous stroma. On immunohistochemical staining, tumor cells were positive for vimentin and negative for smooth muscle actin, CD34, and S100. Our case is unique in that desmoplastic fibroblastoma developed on the scalp and there was presence of pain despite its small size.

A giant trichoblastic carcinoma

  • Lee, Joon Seok;Kwon, Joon Hyun;Jung, Gyu Sik;Lee, Jeong Woo;Yang, Jung Dug;Chung, Ho Yun;Cho, Byung Chae;Choi, Kang Young
    • 대한두개안면성형외과학회지
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    • 제19권4호
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    • pp.275-278
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    • 2018
  • Trichoblastic carcinoma usually occurs as a malignant transformation of the trichoblastoma, but is very rare. A 25-year-old man was admitted with trichoblastoma in the nuchal area with frequent recurrences since birth. The preoperative neck magnetic resonance image revealed lobulated soft tissue lesions involving superficial fascia and infiltrating into both proximal trapezius muscles. In our department, wide excision and reconstruction with a free anterolateral thigh flap were performed. Histological examination revealed skin adnexal carcinoma, originating from the hair follicles, consistent with trichoblastic carcinoma. There was no palpable mass 5 years postoperatively, and there was no recurrence on follow-up positron emission tomography-computed tomography. Trichoblastic carcinomas are rare and difficult to diagnose, but histopathological findings include atypical basaloid keratinocytes with crowded, hyperchromatic nuclei, and increased mitotic activity. The presence of hypercellular stroma is a criterion for distinguishing trichoblastic carcinoma from basal cell carcinoma. A rare giant trichoblastic carcinoma was reported, which was the biggest one in the literature.