• 기본간호학회지
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• 제22권2호
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• pp.190-197
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• 2015

Purpose: Recently, the number of post-stroke survivors has increased. The physical deficits following stroke have been well studied, but there is little information on fear of recurrence in stroke patients. Objective: The purpose of this study was to investigate the health risk behaviors, health motivation and sense of control on fear of recurrence after a stroke. Method: Data were collected through a questionnaire that included items on general characteristics. Participants were recruited from the convalescent centers and outpatients clinics. Participants completed the mastery scale, health motivation scale, and a fear of stroke recurrence scale. The data were analyzed using hierarchial multiple regressions analysis with SPSS version 18.0. Results: Levels of fear of recurrence, health motivation and sense of control were moderate with means of 19.76(SD=5.15), 26.85(SD=5.10), and 16.69(SD=4.65), respectively. Health motivation and sense of control contributed to fear of recurrence. The variables explained 30.5% of variance in fear of recurrence. Conclusions: Results indicate that interventions for fear of recurrence management after stroke should take into account health motivation and sense of control.

• 성인간호학회지
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• 제29권3호
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• pp.302-312
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• 2017

Purpose: The purpose of this study was to identify the following: knowledge of stroke, fear of recurrence and health behaviors among patients with ischemic stroke. Further, factors influencing health behavior will be described. Methods: Data were collected from 180 patients with ischemic stroke at a general hospital. The study instruments included items about general and health related characteristics, a Stroke Knowledge Scale, a Stroke Fear of Recurrence Scale, and a Health Behavior Scale. Hierarchical regression method was conducted to examine predictors of health behavior. Results: The mean age of the participants was $63.62{\pm}11.10years$, and 57.8% of the sample was men. The mean score for stroke knowledge (possible range=0~17) was $14.99{\pm}1.76$, the mean score for fear of recurrence (possible range=0~32) was $23.16{\pm}3.75$, and the mean score for health behavior (possible range=20~80) was $54.69{\pm}6.46$. Stroke knowledge and fear of recurrence were associated with health behavior in patients with ischemic stroke (F=9.98, p<.001, Adjusted $R^2=.43$). Conclusion: The results demonstrated that stroke knowledge and fear of recurrence impacts the health behavior among patients with ischemic stroke. Thus, nursing interventions which focused on fear of recurrence as well as enhancing stroke knowledge could help health behavior in patients with ischemic stroke.

• 대한한의학회지
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• 제28권1호통권69호
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• pp.224-236
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• 2007

Background : Chunghyul-dan is a combinatorial herbal medicine; previous studies reported it had therapeutic effects for microangiopathy, a major part in the progression of small vessel disease, as well as having anti-hypertensive, anti-hyperlipidemic, anti-apoptotic, anti-oxidative, and anti-inflammatory activities. Therefor, we examined the inhibitory effect of Chunghyul-dan on stroke recurrence in patients with small vessel disease. Methods : We prescribed Chunghyul-dan at 600 mg a day to patients with small vessel disease, and monitored stroke recurrence, drug compliances, and adverse effect for 1 year. We then performed follow-up brain MRI to find new vascular lesions after 1 year of Chunghyul-dan medication. For the subjects lost to follow-up, we assessed their prognosis after 1 year by telephone. Results : There were 73 subjects treated with Chunghyul-dan for 1 year; new vascular events were found in 3. Of the 85 subjects lost to follow-up, fifty four could be contacted, and eight of them had stroke recurrence. One year of Chunghyul-dan medication reduced the odds ratio of stroke recurrence by 75% compared to the subjects lost to follow-up and the rate increased to 88%, when adjusted for other relevant risk factors for stroke recurrence. These reductions were much higher than those of aspirin and other kinds of conventional anti-platelets. There was no adverse effect in any of the study subjects. Conclusions : We suggest Chunghyul-dan could be useful for inhibition of stroke recurrence. Further study with a randomized controlled trial is needed to confirm this suggestion.

• Korean Journal of Radiology
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• 제24권4호
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• pp.338-348
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• 2023

Objective: Patients with a history of ischemic stroke are at risk for a second ischemic stroke. This study aimed to investigate the relationship between carotid plaque enhancement on perfluorobutane microbubble contrast-enhanced ultrasonography (CEUS) and future recurrent stroke, and to determine whether plaque enhancement can contribute to risk assessment for recurrent stroke compared with the Essen Stroke Risk Score (ESRS). Materials and Methods: This prospective study screened 151 patients with recent ischemic stroke and carotid atherosclerotic plaques at our hospital between August 2020 and December 2020. A total of 149 eligible patients underwent carotid CEUS, and 130 patients who were followed up for 15-27 months or until stroke recurrence were analyzed. Plaque enhancement on CEUS was investigated as a possible risk factor for stroke recurrence and as a possible adjunct to ESRS. Results: During follow-up, 25 patients (19.2%) experienced recurrent stroke. Patients with plaque enhancement on CEUS had an increased risk of stroke recurrence events (22/73, 30.1%) compared to those without plaque enhancement (3/57, 5.3%), with an adjusted hazard ratio (HR) of 38.264 (95% confidence interval [CI]:14.975-97.767; P < 0.001) according to a multivariable Cox proportional hazards model analysis, indicating that the presence of carotid plaque enhancement was a significant independent predictor of recurrent stroke. When plaque enhancement was added to the ESRS, the HR for stroke recurrence in the high-risk group compared to that in the low-risk group (2.188; 95% CI, 0.025-3.388) was greater than that of the ESRS alone (1.706; 95% CI, 0.810-9.014). A net of 32.0% of the recurrence group was reclassified upward appropriately by the addition of plaque enhancement to the ESRS. Conclusion: Carotid plaque enhancement was a significant and independent predictor of stroke recurrence in patients with ischemic stroke. Furthermore, the addition of plaque enhancement improved the risk stratification capability of the ESRS.

• 대한한의학회지
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• 제28권1호통권69호
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• pp.25-34
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• 2007

Objectives : The present study was carried out to provide basic information necessary for the prevention and efficient treatment of stroke through a comparison between thr patients of the first attack and those of recurrence. Methods : The observation f3r the current study was made on 210 cases of stroke that were confirmed through brain CT-scan. The patients were hospitalized at one of two oriental medical hospitals in Seoul during 2006. Result : The main results were as follows. First, the male-to-female ratio of stroke patients were 1:1.26, with more primary stroke far females and more recurrent stroke for males. Second, in the age distribution, seventies was the top, and sixties, fifties, and forties were next in the order of frequency. A large city was the most frequent residential site and unemployment was the most frequent occupation to have stroke. The incidence of stroke became higher as patients had a taste for spicy and salty food. Third, the most common preceding disease was hypertension. In the relationship of diastolic blood pressure with recurrence, there was significance in the test of independence. Fourth, the most important precipitating conditions at the onset of stroke were rest and steeping. The most common precedent symptoms were verbal disturbance, numbness, and dizziness. In the stroke patients with hemiparesis, male and female patients usually showed It. hemiparesis. Fifth, as a result of brain CT-scan, cerebral hemorrhage was inclined to reduce but cerebral infarction was inclined to increase due to senility and change of lifestyle. Finally, total cholesterol findings disclosed that 22.4% were hypercholesteremia, 18.6 % were hyperlipemia in triglyceride findings, and 19.0% were glycosemia in glucose findings. Conclusions : The above results suggested avoidance of meat and salty fDod and positive control of hypertension and diabetes mellitus in order to prevent stroke.

• Korean Circulation Journal
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• 제52권11호
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• pp.801-807
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• 2022

Percutaneous patent foramen ovale (PFO) closure in patients with a prior PFO-associated stroke showed a risk reduction of the stroke recurrence compared to the medical therapy alone in recent several studies. Nevertheless, optimal patient selection for PFO closure has not been clarified. In this paper, we discuss the characteristics of PFO-associated strokes and discuss the recently published evidence and patient selection for PFO closure in patients with ischemic stroke. The lesions characteristics of PFO-associated stroke are associated with multiple scattered lesion, small sized cerebral cortical lesion, or posterior circulation. Overcoming the failure of early studies in CLOSURE I, PC, and RESPECT trials, PFO closure showed a significant reduction in recurrent stroke in recently published REDUCE, CLOSE, DEFENSEPRO trials, and long-term follow-up data of RESPECT study. However, considering that PFO closure cannot completely prevent stroke recurrence and that complications including atrial fibrillation, we should be selectively performed in patients with high-risk PFO.

• 한국엔터테인먼트산업학회논문지
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• 제14권4호
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• pp.371-380
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• 2020

본 연구는 젊은 뇌졸중 환자의 우울감이 재발염려와 건강관련 삶의 질에 미치는 영향을 파악하고자 실시한 서술적 조사연구로 2018년 7월 24일부터 2018년 11월 22일까지 C도 내 일개 상급종합병원과 J도 내 일개 대학교 병원 신경과 외래를 방문하여 젊은 뇌졸중 환자 240명을 대상으로 조사하였다. 수집된 자료는 SPSS 24.0과 SmartPLS 3.0를 이용하여 통계적인 유의성과 가설검증을 위한 분석을 실시하였다. 우울에 대한 탐색적 요인분석 결과, 죄책감, 정신적 우울, 신체적 우울의 3개의 요인으로 나누어져 추후 분석에 사용되었다. 가설 검증 결과, 우울감 중 죄책감과 정신적 우울이 재발염려에 영향을 미치는 것으로 나타났으며, 정신적 우울이 건강관련 삶의 질에 통계적으로 유의한 영향을 미치는 것으로 나타났다. 또한 재발염려가 건강관련 삶의 질에도 유의한 영향을 미치는 것으로 나타났다. 본 연구 결과를 통해 환자의 죄책감과 정신적 우울 정도를 경감시키기 위한 중재뿐만 아니라 우울감의 조기 사정 및 중재를 통하여 젊은 뇌졸중 환자의 뇌졸중 재발염려를 극복하는 것이 건강관련 삶의 질 향상에 크게 기여할 수 있을 것으로 사료된다.

• Korean Journal of Radiology
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• 제24권5호
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• pp.476-477
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• 2023

• Journal of Yeungnam Medical Science
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• 제10권2호
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• pp.423-431
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• 1993

허혈성 뇌졸중의 재발에 관여된다고 생각되는 주요 위험인자들을 파악하기 위하여 영남대학교 의과대학 부속병원 신경과에 내원한 환자들중 재발된군과 비재발된군을 선정하여 통상적으로 알려진 뇌졸중 위험인자들을 조사하여 그 중 뇌졸중 재발에 영향을 끼치는 요인을 분석 검토하였다. 재발군의 성별은 77명중 남자가 55명, 여자가 22명이었으며, 비재발군은 124명중 남자가 84명, 여자가 40명으로 성별차이를 분석해보면 의미있는 위험인자로 작용하지 못했다. 재발군의 연령은 29세에서 85세까지 평균 62.1세였고 비재발군은 27세에서 90세로 평균연령은 60.7세로 두군 모두 다 60대에서 가장 높은 발병율을 보였고 이 역시 통계적 유의성이 없었다. 당뇨병, 심근경색, 심방세통, 일과성 뇌 허혈증등과 같은 위험 요인이 있더라도 재발에는 영향을 미치지 못한것으로 나타났고 또한 뇌졸중의 병형이나 병변부위도 재발에 미치는 영향은 별로 없는 것으로 조사되었다. 그러나, 고혈압의 병력이나 입원기간중 높은 혈압을 보인 경우는 두군간에 유의성이 있는 차이를 보였다(P<0.05). 이상의 결과로 처음 뇌졸중이 발병하여 입원중 측정한 혈압이 160mmHg/95mmHg 이상으로 높았거나 고혈압의 병력이 있는 경우에는, 그렇지 않은 환자에 비해 향후 2년 내에 허혈성 뇌졸중이 재발할 가능성이 높으므로 적절한 치료로서 예방에 도움을 얻는 것이 필요할 것으로 생각되며, 이외의 위험인자들에 대해서도 지속적 연구가 있어야 할 것으로 사료된다.

• 대한한방내과학회지
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• 제30권4호
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• pp.696-707
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• 2009

Objective : We designed this study to investigate differences between stroke reattack and stroke first attack group to establish fundamental data and prevent a secondary stroke. Methods : 826 subjects were recruited from the patients admitted to the department of internal medicine at Kyung Hee University Oriental Medical Center, Kyung Hee University East-West Neo Medical Center, Kyungwon University Incheon Oriental Medical Center, Kyungwon University Songpa Oriental Medical Center and Dongguk University Ilsan Oriental Medical Center from 1 April 2007 to 31 August 2009. We compared general characteristics, classification of diagnosis, subtypes of cerebral infarction, risk factors, Sasang constitution, diagnostic classifications between stroke reattck and stroke first attack groups. Results : 1. In general characteristics, age differed significantly between the reattck and first attack groups. 2. Classification of diagnosis differed significantly between reattck and first attack groups. 3. In risk factors, hypertension, diabetes mellitus, alcohol drinking, and stress were significantly different between reattck and first attack groups. 4. Diagnostic classifications were significantly different between reattck and first attack groups. Conclusion : To prevent recurrence of stroke, education on stroke risk factors associated with recurrence is needed. In addition, those who are diagnosed as Dampness-Phlegm need to be well-controlled.