• Title/Summary/Keyword: Stroke prediction

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Comparison of Impedance Parameters and Occupational Therapy Evaluation in the Paretic and Non-paretic Upper Extremity of Hemiplegic Stroke Patients

  • Yoo, Chan-Uk;Kim, Jaehyung;Hwang, Youngjun;Kim, Gunho;Shin, Yong-Il;Jeon, Gyerok
    • Journal of Korea Multimedia Society
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    • v.20 no.12
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    • pp.1980-1991
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    • 2017
  • Many stroke patients undergoing rehabilitation therapy require a quantitative indicator for the evaluation of body function in paretic and non-paretic regions. In this study, the impedance parameters were acquired to assess the physical status in the upper extremity of thirty six stroke patients with hemiplegia caused by cerebral hemorrhage (10 patients) and cerebral infarction (26 patients), using bioelectrical impedance. Prediction marker (PM), phase angle (PA), PM/PA, and resistance (R) versus reactance ($X_c$) were utilized to evaluate the functional status of the paretic and non-paretic regions. In addition, the hand grip strength (HGS) and the pinch strength (lateral, palmer, tip) were measured on the upper extremity of hemiplegic stroke patients. PM was distributed in inversely proportional to HGS, but PA was distributed in proportional to HGS. However, there were a number of patients with HGS of 0, regardless of the impedance parameters (PM, PA, R vs. $X_c$). Paretic and non-paretic status in upper extremity of these patients could not be analyzed using impedance parameters. At the rehabilitation therapist's instructions, they were unable to move the hand and fingers of the paretic upper extremity by cranial nerve damage, motor nerve damage, and severe cognitive decline.

Prediction of the Total Effective Moment (ME) Using Stroke Range in Lightweight Piezoelectric Composite Actuator(LIPCA) (경량압전 복합재료 작동기의 작동범위를 이용한 총유효 모멘트 (ME)의 예측)

  • Yoon Kwang-Joon;Kim Cheol-Woong
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.30 no.2 s.245
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    • pp.120-127
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    • 2006
  • The fatigue behavior of LIPCA was so sensitive to the manufacturing condition, the environmental factors and the change of the test apparatus. Therefore, we could be considering not only the relationship between the stroke range $({\Delta}h)$ and actuating frequency but also the relationship between the stroke range $({\Delta}h)$ and the total effective moment $(M^E)$. Thus, this study proposed the calculation method of the applying $M^E$ when the $({\Delta}h)$ of LIPCA was increased from 1.mm to 20mm. To estimate the relationship between the total effective moment $(M^E)$ and the Bernoulli-Euler bending moment (M) was reviewed. And the residual stress distribution of LIPCA and THUNDER using the CLT was evaluated. In conclusions, converting the $({\Delta}h)$ of LIPCA to the radius of curvature (p) and calculating the $(M^E)$, it was found that the p by the $M^E$ changed similarly as the $({\Delta}h)$. It was found that the $M^E$ was 2.2 times as the M. While CFRP and PZT of LIPCA, which had the superior compressive characteristic, had the compressive residual stress, GFRP was subject to the tensile residual stress. Since this reversed configuration between the compressive residuals stress and the tensile one was made, the requirement of the stroke range $({\Delta}h)$ increase was satisfied.

Prediction of cerebral infarction suppression mechanism of the Sagunja-Tang through network pharmacology analysis (네트워크 약리학 분석을 통한 사군자탕(四君子湯)의 뇌경색 억제 기전 예측)

  • Lim, Chiyeon;Lee, Byoungho;Cho, Suin
    • Herbal Formula Science
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    • v.30 no.4
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    • pp.293-304
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    • 2022
  • Objectives : Sagunja-Tang is a famous prescription used in Korean medicine for the purpose of promoting vital energy, and there are few studies using Sagunja-Tang on cerebrovascular diseases yet. As previous studies confirmed that Sagunja-tang is highly likely to be used effectively for stroke, this study was intended to predict the mechanism through which Sagunja-tang would act effectively on stroke. Methods : In this study, a network pharmacology analysis method was used, and oral bioavailability (OB), drug likeness (DL), Caco-2 and BBB permeability were utilized to select compounds with potential activity. For the values of each variable used in this study, OB ≥ 30%, DL ≥ 0.18, Caco-2 ≥ 0, and BBB ≥ 0.3 were applied. Using the above variables, the relations between target genes and diseases that are presumed to be involved in the selected bioavailable compounds were constructed in a network format, and proteins thought to play a major role were identified. Results : Among the compounds included in Sagunja-Tang, 26 bioavailable compounds were selected and it was confirmed that these compounds can be effectively used in cerebrovascular diseases such as Alzheimer's disease and stroke. These compounds are considered to act on proteins related in cell death and growth. The most important mechanism of action was predicted to be apoptosis, and the protein that is thought to play the most key action in this mechanism was caspase-3. Conclusions : In our future study, Sagunja-Tang will be used in an ischemic stroke mouse model, and the mechanism of action will be explored focusing on apoptosis and cell proliferation.

Impact of Asymmetric Middle Cerebral Artery Velocity on Functional Recovery in Patients with Transient Ischemic Attack or Acute Ischemic Stroke (일과성허혈발작 및 급성뇌경색환자에서 경두개도플러로 측정된 중간대뇌동맥 비대칭 지수가 환자 예후에 미치는 영향)

  • Han, Minho;Nam, Hyo Suk
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.2
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    • pp.126-135
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    • 2018
  • This study examined whether the difference in the middle cerebral artery (MCA) velocities can predict the prognosis of stroke and whether the prognostic impact differs among stroke subtypes. Transient ischemic attack (TIA) or acute ischemic stroke patients, who underwent a routine evaluation and transcranial Doppler (TCD), were included in this study. The MCA asymmetry index was calculated using the relative percentage difference in the mean flow velocity (MFV) between the left and right MCA: (|RMCA MFV-LMCA MFV|/mean MCA MFV)${\times}100$. The stroke subtypes were determined using the TOAST classification. Poor functional outcomes were defined as a mRS score ${\geq}3$ at 3 months after the onset of stroke. A total of 988 patients were included, of whom 157 (15.9%) had a poor functional outcome. Multivariable analysis showed that only the MCA asymmetry index was independently associated with a poor functional outcome. ROC curve analysis showed that adding the MCA asymmetry index to the prediction model improved the discrimination of a poor functional outcome from acute ischemic stroke (from 88.6% [95% CI, 85.2~91.9] to 89.2% [95% CI, 85.9~92.5]). The MCA asymmetry index has an independent prognostic value for predicting a poor short-term functional outcome after an acute cerebral infarction. Therefore, TCD may be useful for predicting a poor functional outcome in patients with acute ischemic stroke.

Performance Analysis of the Pintle Thruster Using 1-D Simulation -I : Steady State Characteristics (1-D 시뮬레이션을 활용한 핀틀추력기의 성능해석 -I : 정상상태 특성)

  • Kim, Jihong;Noh, Seonghyeon;Huh, Hwanil
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.43 no.4
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    • pp.304-310
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    • 2015
  • Pintle thrusters use pintle stroke to change nozzle throat area, and this controls thrust. Using MATLAB, one-dimensional simulation has been investigated and the results are compared to those of cold flow tests and computational fluid dynamics for the pintle thruster of Chungnam National University. The prediction based on one-dimensional flow theory shows good agreement with measurements for chamber pressure, but deviates for thrust, partly because of nozzle wall separation. Computational results show that nozzle wall separation occurs at an early stage of nozzle expansion, near the design nozzle throat, for the course of pintle strokes. Empirical thrust prediction incorporates nozzle wall separation, and thus 1-D simulation using empirical thrust prediction showed good results for an early stage of pintle stroke.

Activity recognition of stroke-affected people using wearable sensor

  • Anusha David;Rajavel Ramadoss;Amutha Ramachandran;Shoba Sivapatham
    • ETRI Journal
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    • v.45 no.6
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    • pp.1079-1089
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    • 2023
  • Stroke is one of the leading causes of long-term disability worldwide, placing huge burdens on individuals and society. Further, automatic human activity recognition is a challenging task that is vital to the future of healthcare and physical therapy. Using a baseline long short-term memory recurrent neural network, this study provides a novel dataset of stretching, upward stretching, flinging motions, hand-to-mouth movements, swiping gestures, and pouring motions for improved model training and testing of stroke-affected patients. A MATLAB application is used to output textual and audible prediction results. A wearable sensor with a triaxial accelerometer is used to collect preprocessed real-time data. The model is trained with features extracted from the actual patient to recognize new actions, and the recognition accuracy provided by multiple datasets is compared based on the same baseline model. When training and testing using the new dataset, the baseline model shows recognition accuracy that is 11% higher than the Activity Daily Living dataset, 22% higher than the Activity Recognition Single Chest-Mounted Accelerometer dataset, and 10% higher than another real-world dataset.

Design of Security Keypad Against Key Stroke Inference Attack (입력 위치 유추 방지를 위한 보안 키패드의 설계)

  • Seo, Hwajeong;Kim, Howon
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.26 no.1
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    • pp.41-47
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    • 2016
  • In Black hat USA 2014, a hacking method to infer the password entry of smartphone or smartpad with google glass in distance is presented. In this paper, we design the secure keypad to protect the key stroke inference attacks with google glass which has unique layout ensuring same input entry but different input value.

A Study on Performance Simulation of an Reciprocating Engine for Small Long Endurance Unmanned Aerial Vehicles (소형 장기체공 무인기용 왕복엔진 성능 예측 시뮬레이션 연구)

  • Chang Sung-Ho;Koo Sam-Ok;Shin Younggy
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.29 no.7 s.238
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    • pp.820-827
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    • 2005
  • Development of an engine with good fuel economy is very important for successful implementation of long endurance miniature UAVs (unmanned aerial vehicles). In the study, a 4-stroke glow-plug engine was modified to a gasoline-fueled spark-ignition engine. Engine tests measuring performance and friction losses were conducted to tune a simulation program for performance prediction. It has been found that excessive friction losses are caused by insufficient lubrication at high speeds. The simulation program predicts that engine power and fuel economy get worse with high altitude due to increasing portion of friction losses. The simulation results suggest quantitative guidelines for further development of a practical engine.

Study on the prediction of performance and emission of a 4-cylinder 4-stroke cycle spark ignition engine (4기통 4사이클 스파크 점화기관의 성능 및 배기조성 예측에 관한 연구)

  • 유병철;최영돈;윤강식
    • Journal of the korean Society of Automotive Engineers
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    • v.10 no.4
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    • pp.39-56
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    • 1988
  • In this study, the computer program was developed to predict the engine performances and exhaust emissions of a 4-cylinder 4-stroke cycle ignition engine including intake and exhaust system. The simulation models applied to each process were as follows. For the combustion process, two zone model which requires only one empirical constant was applied, and for the gas exchange process, the method of characteristics that allows the calculations of the time variation and spatial variation of properties along the pipes was used. Constant pressure perfect mixing model was applied to take into account of the interaction at manifold branches. To predict exhaust emissions, twelve chemical species were considered to be present in combustion products. These species were calculated through equilibrium thermodynamics and kinetic theory. The empirical constants reduced to least number as possible were determined through the comparison with the experimental indicator diagram of one particular operating condition and these constants were applied to other operating conditions. The predicted performances and emissions were compared with the experimental results over the wide range of operating conditions.

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Discriminant Model for Pattern Identifications in Stroke Patients Based on Pattern Diagnosis Processed by Oriental Physicians (전문가 변증과정을 반영한 중풍 변증 판별모형)

  • Lee, Jung-Sup;Kim, So-Yeon;Kang, Byoung-Kab;Ko, Mi-Mi;Kim, Jeong-Cheol;Oh, Dal-Seok;Kim, No-Soo;Choi, Sun-Mi;Bang, Ok-Sun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.6
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    • pp.1460-1464
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    • 2009
  • In spite of many studies on statistical model for pattern identifications (PIs), little attention has been paid to the complexity of pattern diagnosis processed by oriental physicians. The aim of this study is to develop a statistical diagnostic model which discriminates four PIs using multiple indicators in stroke. Clinical data were collected from 981 stroke patients and 516 data of which PIs were agreed by two independent physicians were included. Discriminant analysis was carried out using clinical indicators such as symptoms and signs which referred to pattern diagnosis, and applied to validation samples which contained all symptoms and signs manifested. Four Fischer's linear discriminant models were derived and their accuracy and prediction rates were 93.2% and 80.43%, respectively. It is important to consider the pattern diagnosis processed by oriental physicians in developing statistical model for PIs. The discriminant model developed in this study using multiple indicators is valid, and can be used in the clinical fields.