• 제목/요약/키워드: Strategic factor

검색결과 654건 처리시간 0.029초

의약품 물류센터 입지 개선 방안에 관한 연구 (A Study on the Location Improvement of the Pharmaceutical Logistics Center)

  • 조삼현;조상리
    • 한국항만경제학회지
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    • 제35권3호
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    • pp.41-60
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    • 2019
  • 본 연구는 의약품 물류업체를 대상으로 물류센터 선정시 고려하는 요인들을 파악하고 그 요인들에 대한 중요도-만족도를 분석함으로 현재의 의약품 물류센터입지의 개선방안을 제공하였다. 첫째, 물류센터선정시 고려요인은 물류요인, 경제요인, 환경요인, 정책요인으로 구분되고 각 요인에 포함된 구체적인 속성들에 대해서는 대부분이 중요도에 비해 만족도가 낮은 것으로 나타났다. 둘째, 의약품 물류센터 이용자들은 생산업체, 유통업체, 병-의원, 약국으로 구분하고 각 이용자별 분석결과, 물류 요인은 개선이 필요하고 환경요인은 과잉투자된 것으로 확인되었다. 이러한 연구 결과는 향후 의약품 유통업체들이 물류센터를 선정하는데 있어 방향성을 제시해 줄 수 있으며, 전략적 시사점을 제공할 수 있을 것으로 기대한다.

Nrf2 in TIME: The Emerging Role of Nuclear Factor Erythroid 2-Related Factor 2 in the Tumor Immune Microenvironment

  • Jialin Feng;Oliver J. Read;Albena T. Dinkova-Kostova
    • Molecules and Cells
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    • 제46권3호
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    • pp.142-152
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    • 2023
  • Nuclear factor erythroid 2-related factor 2 (Nrf2) mediates the cellular antioxidant response, allowing adaptation and survival under conditions of oxidative, electrophilic and inflammatory stress, and has a role in metabolism, inflammation and immunity. Activation of Nrf2 provides broad and long-lasting cytoprotection, and is often hijacked by cancer cells, allowing their survival under unfavorable conditions. Moreover, Nrf2 activation in established human tumors is associated with resistance to chemo-, radio-, and immunotherapies. In addition to cancer cells, Nrf2 activation can also occur in tumor-associated macrophages (TAMs) and facilitate an anti-inflammatory, immunosuppressive tumor immune microenvironment (TIME). Several cancer cell-derived metabolites, such as itaconate, L-kynurenine, lactic acid and hyaluronic acid, play an important role in modulating the TIME and tumor-TAMs crosstalk, and have been shown to activate Nrf2. The effects of Nrf2 in TIME are context-depended, and involve multiple mechanisms, including suppression of proinflammatory cytokines, increased expression of programmed cell death ligand 1 (PD-L1), macrophage colony-stimulating factor (M-CSF) and kynureninase, accelerated catabolism of cytotoxic labile heme, and facilitating the metabolic adaptation of TAMs. This understanding presents both challenges and opportunities for strategic targeting of Nrf2 in cancer.

의료기관 선택기준에 관한 연구 (A Study on the Criteria for Selection of Medical Care Facilities)

  • 조우현;김한중;이선희
    • Journal of Preventive Medicine and Public Health
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    • 제25권1호
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    • pp.53-63
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    • 1992
  • There are increasing interest and need for information on health care consumer with the significance of hospital marketing and strategic planning being increasingly emphasized. This study was conducted to investigate the criteria for selection of medical facilities according to the characteristics of health care consumer by the types of medical services on a sample of 1,500 population aged 20 years and above. Major findings are as follows ; 1. When considering the criteria for selection of medical facilities into two factors, namely, quality or convenience factors, convenience factor was the major contributor for outpatient and dental services whereas it was quality factor for inpatient services. 2. Females and those residing in large cities selected medical facilities based on convenience factor in the outpatient services. In the case of inpatient service, persons who considered their present health status to be good and whose ages were 50 years old and above choose medical facilities based on quality factor. 3. Persons who considered medical facilities to be profit-making tended to choose medical facilities based on convenience factor for outpatient services. There were no differences in the cases of inpatient and dental services. 4. There was no significant difference on the criteria for selection of medical facilities according to the decision maker for selection or trust on medical facilities. On the use of health service information, selection of medical facilities was based on quality factor for those who made more use of the information in the cases of outpatient and dental services. 5. Analysis using the logistic regression model on the criteria for the selection of medical facilities with the characteristics of health care consumer as independent variables was performed. The selection of medical facilities was significantly related with residential area, sex, and use of information on medical facilities for outpatient services and with age, average monthly income, and perception of health status for inpatient services. For dental services significant association with residential area and use of information on medical facilities was seen. The results of this study, despite some limitations, can be used as baseline data for marketing and strategic planning of hospital management.

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Children′s Representations of Numbers

  • Park, Man-Goo
    • 한국수학교육학회지시리즈D:수학교육연구
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    • 제6권1호
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    • pp.29-38
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    • 2002
  • The purpose of this paper was to examine early numerical representations between American and Korean children. Fifty-five first graders (35 Korean and 20 American) participated in the study. According to the findings of the current study, the author concluded that the Korean children had a stronger conception of base ten representations of numbers than that of the American children. The Korean children used various strategic reasoning such as decomposition and recomposition on the basis of base 10 structure to solve addition and subtraction problems effectively. However, the author cannot conclude that language differences would be the largest factor that would make Korean children sapient in the representations of base ten structures.

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Biotechnology and Biomedicine - a Case Study with Recombinant Limulus Factor C

  • Ling, Ding-Jeak;Ho-Bow
    • 대한의생명과학회지
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    • 제8권1호
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    • pp.1-5
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    • 2002
  • Biotechnology "embraces everything from the production of recombinant proteins to the use of biological molecules as components of nanotechnology". Strategic-basic research in biotechnology is crucial to boosting world economy and creating jobs in the Life Sciences. Biotechnology will be the benefit to be drawn from biomedical life science research, which promises to be the new pillar of economy. Although the turnaround time for life science research products is painstakingly slow, the fruits of one such labour (Fig. 1), is being reaped fur worldwide biomedical applications.

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중국관강객 유치전략으로서의 현대중국식문화에 관한 연구 (I)

  • 김미자
    • 한국조리학회지
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    • 제4권
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    • pp.95-127
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    • 1998
  • Recently the number of Chinese tourist in increasing. The purpose of this study is understanding of Chinese tourist's character and food culture. The tourist food service industry has become an important factor in choice tourist destination, This study is composed of six chapter as follow: Chapter Ⅰ : The purpose and the method of study Chapter Ⅱ : Change of Chinese Life Level & Environment Progress and situation of Chapter Ⅲ : Chinese Food culture and dining out trend Chapter Ⅳ : Alternatives of strategic food service environment Chapter Ⅴ : Conclusion

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지적자본(知的資本) 측정모형(測定模型)에 관한 연구(硏究) (A Study on Intellectual Capital Measuring Model)

  • 이의현;천명섭
    • 산업융합연구
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    • 제3권1호
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    • pp.145-168
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    • 2005
  • This study on intellectual capital which is in spotlight as an important factor has meaning that it provides information on intellectual capital to interested parties(stockholders, employers, employees, customers, etc.), suggests intellectual capital measurement indices for strategic management of human resources, and presents intellectual capital management process which is useful in companies practically by designing and verifying intellectual capital measurement models for effective management of intellectual capital.

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가상기업의 성공적 구현을 위한 영향요인에 관한 연구 -자동차부품산업을 중심으로- (An Empirical Study on The Influence Factor of Virtual Enterprise Implementation in Automobile Part Industry)

  • 문태수
    • Journal of Information Technology Applications and Management
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    • 제10권3호
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    • pp.121-142
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    • 2003
  • Most of companies related to the area of B2B electronic commerce are making their efforts to innovate their existing business process into new designed process based on the concept of virtual enterprise. Virtual enterprise can take on many forms and definitions. Nevertheless, the rationale for this business model is clear cooperate to compete, the virtual organization advocates collaboration, partnerships, alliance and similar ideas. This studyintends to suggest an empirical clue to test several hypotheses related to the influence of environmental. organizational, and technological factor to the successful implementation of virtual enterprise in automobile industry. This research surveyed 91 corporations in Korean automobile part industry. Among those samples 86 data of corporate general managers turned out to be statistically valid. This study performed the factor analysis, Cronbach-alpha test. Pearson correlation analysis for testing the validity and the reliability of this research. The results of factor analysis and reliability test indicate that thirty issues to be surveyed are to be grouped into nine factors. The result of multiple regression shows that the influencing factors of eight independent variables on a dependent variable are cooperation between partners, information intensity, IT compatibility, IS maturity. The partners in the strategic alliance will have to trust each other in carrying out their designated roles and responsibilities. and supplying the correct information critical for creating value in virtual business environment.

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HR부서의 전략적 역할이 교육훈련만족도를 매개로 조직유효성에 미치는 영향: 제조업을 중심으로 (The Influence of HR Department's Strategic Role on Organizational Effectiveness through Education and Training Satisfaction: Focusing on the Manufacturing Industry)

  • 최재원;이석기;김성동
    • 디지털융복합연구
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    • 제19권6호
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    • pp.175-184
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    • 2021
  • 본 연구의 목적은 우리나라 제조업이 당면한 위기를 극복하기 위한 혁신의 주체인 인적자원 관련 업무를 담당하는 인사 부서의 전략적 역할이 교육훈련만족을 통해 조직유효성에 미치는 영향을 알아보는 것이다. 제 7 차 인적자본회사패널 설문조사 데이터 중 제조업 데이터를 활용하였으며, 구조 방정식 모델을 통해 분석되었다. 본 연구의 결과는 첫째, HR 부서의 전략적 역할이 교육훈련 만족도에 긍정적인 영향을 미치는 것으로 나타났다. 둘째, 교육훈련 만족도 및 HR부서의 전략적 역할은 조직유효성 중 직무만족에 긍정적인 영향을 미친다. 셋째, 교육훈련 만족도는 HR 부서의 전략적 역할과 직무만족의 관계에 매개효과가 있음을 확인하였다. 본 연구의 결과는 혁신뿐만 아니라 중소기업이 직면한 위기를 극복하는데 중요한 요소인 인사 전담부서의 권한과 책임을 확대하고 그들의 역할을 재정립하는 기반이 될 것으로 기대한다. 이 연구의 초점은 제조에만 있으므로 더 다양한 산업 분야로 연구를 확대되어야 할 것이다.

한국 수출입 제조 기업의 국제표준인증 활용과 파트너십 프로세스에 대한 연구 (An Empirical Research how ISO application and Partnership process affect on Business Performance of Import and Export Manufacturing Firms in Korea)

  • 김창봉;구윤철
    • 통상정보연구
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    • 제18권2호
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    • pp.131-150
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    • 2016
  • 최근 글로벌 무역 공급체인관리는 글로벌 비즈니스에서 국제표준인증이 파트너십을 형성하는데 중요한 요인으로 등장이 되고 있다. 글로벌 기업들은 생산과 판매를 전 세계지역에 동시에 진행하기 때문에 글로벌 파트너를 결정하는데 국제표준인증 활용이 기업의 성과에 중요한 영향을 미친다. 우리나라 수출입 제조 기업들은 국제표준인증 인증을 획득하여 글로벌 파트너십을 구축하는 노력을 기울이고 있다. 따라서 본 연구에서는 국제표준인증 활용의 전략적 수준과 운영적 수준, 파트너십 프로세스의 신뢰, 몰입, 협력 요인이 기업의 사업성과에 미치는 구조적 관계를 규명하였다. 이를 위해서 우리나라 수출입 제조기업 147개 기업을 대상으로 설문조사를 진행하였고, 구조방정식모형(Structural equation model)으로 실증분석을 실시하였다. 본 연구의 가설검증 결과 다음과 같은 연구결과를 도출하였다. 첫째, 국제표준인증 전략적 수준은 신뢰, 몰입에 긍정적인 영향을 미쳤다. 둘째, 국제표준인증 운영적 수준은 신뢰, 협력에 긍정적인 영향을 미쳤다. 셋째, 파트너십 프로세스의 신뢰는 몰입에 긍정적인 영향을 미쳤고, 몰입은 협력에 긍정적인 영향을 미쳤다. 넷째, 파트너십 프로세스의 협력은 기업의 사업성과에 긍정적인 영향을 미쳤다. 본 연구의 시사점은 기업들이 파트너십을 구축할 때 국제표준인증 활용 수준 정도에 따라 비즈니스 성과에 영향을 미친다. 기업의 사업성과를 향상시키기 위해서는 신뢰, 몰입, 협력의 파트너십 프로세스가 글로벌 무역 공급체인망 구축과 파트너십을 유지하는 주요한 요인으로 연구결과가 도출되었다.

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