• Journal of Korea Technology Innovation Society
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• v.20 no.3
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• pp.576-606
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• 2017

It is more salient in the high-tech industry to cooperate even among competitors in order to promptly respond to the changes in product architecture. In this sense, 'co-opetition,' which is the combination word between 'cooperation' and 'competition,' is the new business term in the strategic management and represents the two concepts "simultaneously co-exist." From this view, this study set up the research purposes as follows: 1) investigating the corporate managerial and technological behavioral characteristics in the co-opetition of the global display industry. 2) verifying the emerging factors during the co-opetition behavior hereafter. 3) suggesting the strategic direction focusing on the co-opetition behavioral characteristics. To this end, this study used co-word network analysis to understand the structure in context level of the co-opetition. In order to understand topics on each network, we clustered the keywords by community detection algorithm based on modularity and labeled the cluster name. The results show that there were increasing patterns of competition rather than cooperation. Especially, the litigations for mutual control against Korean firms much more severely occurred and increased as time passed by. Investigating these network structure in technological evolution perspective, there were already active cooperation and competition among firms in the early 2000s surrounding the issues of OLED-related technology developments. From the middle of the 2000s, firm behaviors have focused on the acceleration of the existing technologies and the development of futuristic display. In other words, there has been competition to take leadership of the innovation in the level of final products such as the TV and smartphone by applying the display panel products. This study will provide not only better understanding on the context of the display industry, but also the analytical framework for the direction of the predictable innovation through analyzing the managerial and technological factors. Also, the methods can support CTOs and practitioners in the technology planning who should consider those factors in the process of decision making related to the strategic technology management and product development.

• Nutrition Research and Practice
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• v.16 no.1
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• pp.14-32
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• 2022

BACKGROUND/OBJECTIVES: Peroxisome proliferator-activated receptor-gamma co-activator-1α (PGC-1α) has a central role in regulating muscle differentiation and mitochondrial metabolism. PGC-1α stimulates muscle growth and muscle fiber remodeling, concomitantly regulating lactate and lipid metabolism and promoting oxidative metabolism. Gynostemma pentaphyllum (Thumb.) has been widely employed as a traditional herbal medicine and possesses antioxidant, anti-obesity, anti-inflammatory, hypolipemic, hypoglycemic, and anticancer properties. We investigated whether G. pentaphyllum extract (GPE) and its active compound, gypenoside L (GL), affect muscle differentiation and mitochondrial metabolism via activation of the PGC-1α pathway in murine C2C12 myoblast cells. MATERIALS/METHODS: C2C12 cells were treated with GPE and GL, and quantitative reverse transcription polymerase chain reaction and western blot were used to analyze the mRNA and protein expression levels. Myh1 was determined using immunocytochemistry. Mitochondrial reactive oxygen species generation was measured using the 2'7'-dichlorofluorescein diacetate assay. RESULTS: GPE and GL promoted the differentiation of myoblasts into myotubes and elevated mRNA and protein expression levels of Myh1 (type IIx). GPE and GL also significantly increased the mRNA expression levels of the PGC-1α gene (Ppargc1a), lactate metabolism-regulatory genes (Esrra and Mct1), adipocyte-browning gene fibronectin type III domain-containing 5 gene (Fndc5), glycogen synthase gene (Gys), and lipid metabolism gene carnitine palmitoyltransferase 1b gene (Cpt1b). Moreover, GPE and GL induced the phosphorylation of AMP-activated protein kinase, p38, sirtuin1, and deacetylated PGC-1α. We also observed that treatment with GPE and GL significantly stimulated the expression of genes associated with the anti-oxidative stress response, such as Ucp2, Ucp3, Nrf2, and Sod2. CONCLUSIONS: The results indicated that GPE and GL enhance exercise performance by promoting myotube differentiation and mitochondrial metabolism through the upregulation of PGC-1α in C2C12 skeletal muscle.

• Nutrition Research and Practice
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• v.16 no.6
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• pp.685-699
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• 2022

BACKGROUND/OBJECTIVES: Platycodon grandiflorum (PG) has long been known as a medicinal herb effective in various diseases, including bronchitis and asthma, but is still more widely used for food. Fermentation methods are being applied to increase the pharmacological composition of PG extracts and commercialize them with high added value. This study examines the hydrolyzed and fermented PG extract (HFPGE) fermented with Lactobacillus casei in RAW 264.7 cells, and investigates the effect of amplifying the immune and the probable molecular mechanism. MATERIALS/METHODS: HFPGE's total phenolic, flavonoid, saponin, and platycodin D contents were analyzed by colorimetric analysis or high-performance liquid chromatography. Cell viability was measured by the MTT assay. Phagocytic activity was analyzed by a phagocytosis assay kit, nitric oxide (NO) production by a Griess reagent system, and cytokines by enzyme-linked immunosorbent assay kits. The mRNA expressions of inducible nitric oxide synthase (iNOS) and cytokines were analyzed by reverse transcription-polymerase chain reaction, whereas MAPK and nuclear factor (NF)-κB activation were analyzed by Western blots. RESULTS: Compared to PGE, HFPGE was determined to contain 13.76 times and 6.69 times higher contents of crude saponin and platycodin D, respectively. HFPGE promoted cell proliferation and phagocytosis in RAW 264.7 cells and regulated the NO production and iNOS expression. Treatment with HFPGE also resulted in increased production of interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, C-X-C motif chemokine ligand10, granulocyte-colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and monocyte chemoattractant protein-1, and the mRNA expressions of these cytokines. HFPGE also resulted in significantly increasing the phosphorylation of NF-κB p65, extracellular signal-regulated kinase, and c-Jun N-terminal kinase. CONCLUSIONS: Taken together, our results imply that fermentation and hydrolysis result in the extraction of more active ingredients of PG. Furthermore, we determined that HFPGE exerts immunostimulatory activity via the MAPK and NF-κB signaling pathways.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.36 no.4
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• pp.45-58
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• 2013

Korean local governments have been planning for u-City construction with great efforts. Such efforts are needed in order to reflect the urban characteristics of each city, to promote local economic growth, and to have a sustainable operation model. Thus it is critical at an earlier stage to set a strategic direction based on urban environment analysis, which will lead to a feasible implementation of u-City. This paper derives issues and suggests improvement methods based on a case study on the USPs (u-City Strategy Planning's) of ten local governments. It is expected that the improvement methods will greatly reduce risks involved in u-City construction and contribute to better provided local-specific u-services.

• Journal of The Korean Digital Architecture Interior Association
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• v.8 no.2
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• pp.47-56
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• 2008

The purpose of this study is to arrange the design elements and methods for sustainable community. After made the concept of sustainable community clear in the contemporary architecture and urban design, this study examines rural ecovillage, urban demonstration project, co-housing, new urbanism and urban village, and ecological township as the application modes of sustainable community. Through the cases of the application mode, the design elements for sustainable community were summarized as the followings: the symbiosis system with the nature, permaculture and edible landscape, identity, the technology for saving of resources and energy, the traffic system for the reduction of private motor use, mixed use development, and the housing with diversity. And the design methods for sustainable community were summarized as the followings: strategic planning, visioning, community action planning, workshops and charrette, environmental evaluation, and participation techniques.

• Journal of East-West Nursing Research
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• v.14 no.2
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• pp.39-46
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• 2008

Purpose: The study was undertaken from June 1 to July 15, 2008 to assess the effect of social support on self-esteem and life satisfaction in elderly volunteers. Methods: Social support, self-esteem, and life satisfaction were determined using previously established and accepted methods. Data analyses included frequency, ANOVA, t-test, Pearson correlation coefficient, and simple regression. Results: Subjects' social support, self-esteem, and life satisfaction were closely related. The relationships of social support/self-esteem, social support/life satisfaction, and self-esteem/life satisfaction were significant. Social support accounted for 15% of self-esteem and 12% of life satisfaction. Conclusions: Social support is a very important factor influencing self-esteem and life satisfaction of the elderly. Social support, which sustains the mental health of the elderly, represents one of the best strategic nursing interventions.

• Journal of Information Technology Applications and Management
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• v.24 no.3
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• pp.107-123
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• 2017

This study uses the concept of dominant design to identify the determinants for the emergence of a next-generation dominant electronic display. It employs multiple research methods with the participation of display experts, which combine case studies, an unstructured interview, and the Delphi method. The results show that based on technological innovation and market dominance, a next-generation dominant display is more likely to emerge as a result of technological competition between liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs). The findings emphasize that the importance of rapid technological innovation, including component and process innovations, and a competitive edge in manufacturing costs are important. The study sheds light on our understanding of dominance in an industry and market, and also provides strategic guidance for practitioners to establish a competitive strategy.

• Journal of the Korean Society of Industry Convergence
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• v.26 no.4_2
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• pp.687-696
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• 2023

In recent construction sites, digital maps obtained through drone photogrammetry have garnered increasing attention as indispensable tools for effective construction site management. the strategic placement of Ground Control Points (GCPs) is crucial in drone photogrammetry. Nevertheless, the manual labor and time-intensive nature of GCP surveying pose significant challenges. The purpose of this study is to design the concept of automated GCPs survey technology for enhancing drone photogrammetry efficiency in construction sites. As a result, the productivity of the automated method was analyzed as 118,894.7㎡/hr. It is over 25% productivity improvement compared to traditional methods. In future studies, economic analysis of automated methods should be studied.

• International conference on construction engineering and project management
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• 2020.12a
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• pp.433-439
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• 2020

As eco-friendly and sustainable architecture is becoming more popular, the interest in Korean traditional wooden buildings (Hanok) has also been increasing. The building technologies of the wooden construction have been actively developed in all over the world through the diversification of new materials and construction methods. On the other hand, the growth rate of wooden construction market is still slow in Korea. In an attempt to promote the Korean traditional wooden buildings, a comprehensive research project has been conducted. This R&D project is developing standard designs, new materials, and methods for modernized Hanok including houses, public buildings, long-span structures, and even high-rise buildings. To this end, the purpose of this study is to formulate a technological strategy for popularization of modernized Hanok. Influencing variables and issues are analyzed and defined first. At the same time, the five keywords have examined in the perspective of dissemination of modernized Hanok technology. Finally, a technology road map for strategic development of modernized Hanok is proposed through casual diagrams.

• International conference on construction engineering and project management
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• 2024.07a
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• pp.753-760
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• 2024

Warehouses and Self-Storage facilities are essential for e-commerce operations, providing inventory, distribution, and delivery space. As per the Bureau of Labor Statistics, the number of warehousing and storage businesses in the United States increased from 15,152 in 2010 to 20,002 in 2021, showing continuous growth over the decade. Given the recent surge, there is a need to better understand the impact of these delivery methods on the quality metrics of these facilities. This study aims to contrast the measure of quantitative quality performance of design-build (DB) versus traditional design-bid-build (DBB) project delivery methods (PDM) for warehouses and self-storage facilities. This research conducted a literature review to document quality metrics to compare DBB and DB on project performance. ANOVA was conducted to compare the significant difference between the means to compare the performance between delivery methods and project outcomes across these critical areas. With these insights, owners can make informed strategic decisions about selecting the optimal PDM for future storage facility projects based on their unique quality and scope management objectives.