• Korean Journal of Veterinary Research
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• v.39 no.2
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• pp.318-326
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• 1999

Respiratory pathogenic effects of several porcine reproductive and respiratory syndrome virus(PRRSV) isolates were examined in swine tracheal ring(STR) cultures by examining their effect on ciliary activity. One high and one low pathogenic PRRSV isolates were then selected and their pathogenicity investigated in 3-week-old conventional PRRSV-seronegative pigs. Ten pigs each were inoculated intranasally with the high or low pathogenic PRRSV isolate and 6 pigs were sham inoculated as negative controls. Two pigs each from the inoculated group and one pig each from negative control group were killed on 4, 7, 14, 21 and 28 days postinoculation(pI). At necropsy, degrees of gross lung lesion was determined. Turbinate, tonsil, trachea and lung samples were collected for virus isolation or histopathology. Gross lung lesions were observed mainly on 14 days PI with high and low pathogenic isolates inducing moderate diffuse and mild gross lung lesions, respectively. Inoculation of either the high or low pathogenic virus resulted in loss of cilia in ciliated epithelium of turbinates and trachea between 7 and 28 days PI. High pathogenic virus caused increased number of Goblet cells in the tracheal epithelial layer between 4 and 21 days PI whereas the low pathogenic virus did it between 14 and 28 days PI and with a lesser degree. Although both viruses produced interstitial pneumonia, the lesion was less severe with the low pathogenic virus. The isolation of high pathogenic virus from tissues and sera was earlier and more consistent than that of the low pathogenic virus. The agreement between in vitro and in vivo tests indicates that STR cultures may be used as a routine method to determine the respiratory pathogenicity of PRRSV isolates.

• Journal of KIISE:Databases
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• v.31 no.2
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• pp.150-162
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• 2004

Moving objects have characteristics that they change continuously their positions over time. The movement of moving objects should be stored on trajectories for processing past queries. Moving objects databases need to provide spatio-temporal index for handling moving objects queries like combined queries. Combined queries consist of a range query selecting trajectories within a specific range and a trajectory query extracting to parts of the whole trajectory. Access methods showing good performance in range queries have a shortcoming that the cost of processing trajectory Queries is high. On the other hand, trajectory-based index schemes like the TB-tree are not suitable for range queries because of high overlaps between index nodes. This paper proposes new TR(Trajectory Riving)-tree which is revised for efficiently processing the combined queries. This index scheme has several features like the trajectory preservation, the increase of the capacity of leaf nodes, and the logical trajectory riving in order to reduce dead space and high overlap between bounding boxes of nodes. In our Performance study, the number of node access for combined queries in TR-tree is about 25% less than the STR-tree and the TB-tree.

• Korean Journal of Food Science and Technology
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• v.27 no.5
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• pp.646-651
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• 1995

The correlation between the bitter taste and the surface tension was found for bitter tasting, aqueous solutions. By the Szyszkowski's equation, the surface tension (STR) and taste curves (JND) were derived more clearly using the Techplot program. The specific capillary activity (log b values) for bitter tasting solutions are negatively correlated to the recognition threshold. It was shown that a more bitter substances has greater capillary activity. The correlation between the recognition threshold $(log\;C_{1})$ and the substance specific constant (a and b values) of sensory (JND) and surface tension values indicates good agreement. This means that the model of surface area adsorption in the solution/air system can apply also for the sensory model microvillus membrane in the mouth.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.23 no.4
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• pp.857-864
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• 1998

The infuluence of Doppler effects on the tracking performance of a noncoherent second-order delay locked loop (DLL) operating on a data modulated signal is investigated. For the perfoermance analysis we consider the tracking accuracy (steady state error and jitter) of the linear DLL and the reliability of the nonlinear loop. The nonlinear analysis concerning the loop reliability makes use of an asympototic expansion for the MTLL(mean time to lose lock) which has been derived by applying the singular perturbation method. In particular, we give optimal loop parameters and the optimal bandwidth of the bandpass filter in the loop arms to achieve a maximum MTLL. Since Doppler effects can be producesd comparatively in LEO system, we can espect the more reliable DLL loop design. by using the results of the circuit simulation, the delay lock loop is synthesized in FPGA, and verified to get the GPS data from the STR-2770 GPS simulator system. So, the synthesized logic circuit is shown be accurately performed.

• Nuclear Engineering and Technology
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• v.27 no.3
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• pp.336-343
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• 1995

The Self Tuning Regulator(STR) method which is an approach of adaptive control theory, is ap-plied to design the fully automatic power controller of the nonlinear reactor model. The adaptive control represent a proper approach to design the suboptimal controller for nonlinear, time-varying stochastic systems. The control system is based on a third­order linear model with unknown, time-varying parameters. The updating of the parameter estimates is achieved by the recursive extended least square method with a variable forgetting factor. Based on the estimated parameters, the output (average coolant temperature) is predicted one-step ahead. And then, a weighted one-step ahead controller is designed so that the difference between the output and the desired output is minimized and the variation of the control rod position is small. Also, an integral action is added in order to remove the steady­state error. A nonlinear M plant model was used to simulate the proposed controller of reactor power which covers a wide operating range. From the simulation result, the performances of this controller for ramp input (increase or decrease) are proved to be successful. However, for step input this controller leaves something to be desired.

• Journal of Veterinary Clinics
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• v.25 no.5
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• pp.346-354
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• 2008

The combined effects of EDTA-Tris and eighteen antimicrobial agents have been evaluated in eight clinically isolated methicillin-resistant bacteria (Staphylococcus aureus, Escherichia coli, Streptococcus uberis and Streptococcus agalactiae) from bovine mastitis. The antimicrobial activity was evaluated by measuring the minimal bactericidal concentration (MBC) for the antibiotics alone or in combination with EDTA-Tris in Mueller-Hilton broth and milk. Combined use of EDTA-Tris and antibiotics potentiated or antagonized activity of antibiotics against mastitic pathogens. Milk increased the antibiotic potency of erythromycin and spiramycin on S. aureus. Culture in milk changed patterns of EDTA-Tris combinational effects compared with that in standard Mueller-Hilton broth. Combined with EDTA-Tris in milk, synergic effects were observed in colistin, dihydrostreptomycin, kanamycin, erythromycin, gentamycin, oxytetracycline, streptomycin to E. coli, Str. uberis, and Str. agalactiae. However, significant antagonistic effects of milk on antibiotic susceptibility in combination with EDTA-Tris were noted in neomycin, streptomycin, penicillin, roxithromycin, and amoxicillin. This study indicates that combination therapy of EDTA-Tris with antibiotics in bovine mastitis should be used with caution because of the possible antagonistic effects of antibiotic combination with EDTA-Tris on mastitic pathogens. In addition, antibiotic susceptibility test in combination with EDTA-Tris in milk culture condition can be benefit in search of effective treatment regimen for some antibiotic-resistant bacteria of mastitis.

• Journal of Korean Society of Water and Wastewater
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• v.18 no.2
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• pp.254-269
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• 2004

Polysilicato-iron coagulant (PSI) is receiving attention in Japan as a substitute for aluminum-based coagulants. In the first part of this article, coagulation, sedimentation and filtration experiments were carried out using kaolin clay particles as the turbidizing material and four types of PSI with various molar ratios of polysilicic acid to ferric chloride (Si/Fe ratio). Results demonstrate that use of a PSI with a high Si/Fe ratio can cause a more dramatic decrease in treated water turbidity but a higher suction time ratio (STR) than when PACl is used. However, optimization by increasing the rapid agitation strength GR is found to greatly improve the STR. In addition, the series of filtration experiments verified that optimization of GR is greatly effective in controlling rapid increases in filter head loss, and also formation of a thin aging layer in the upper part of the filter bed by slow-start filtration is effective in improving filtered water turbidity over the entire filtration process. The second part of this article describes two innovative filtration techniques to increase the particle separation efficiency; (1) coagulant-coated filter medium by enhancing the electrical potential of the surface of the filter medium, and (2) coagulant dosing in influent by controlling the electrical potential of particles entering the filter layer. From the results of the various filtration experiments using a pilot plant, these two techniques were found to be very effective to reduce the effluent water turbidity from the start to the end of a filter run. Moreover, in the filtration experiments using these two methods simultaneously, higher removal efficiency of approximately 3-log (99.7%) was realized, resulting that the finished water turbidity was accordingly reduced to 0.004mg/L.

• KSBB Journal
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• v.15 no.1
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• pp.88-95
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• 2000

We have produced new-structured oligosaccharides using immoobilized mixed-enzyme reactor of destransucrase from Leuconostoc mesenteroides B-512FMCM and $\alpha$-amylase from Aspergillus oryzae. The reactors of immobilized mixed-exzyme beads were more efficient for the production of oligosaccharides than that of each immobilized enzyme bead in stirred-tank reactior(STR) or in packed-bed reactor(PCR). In continuous flow reactor, the immobilized mixed-enzyme bead in PBR was more stable than in STR, and 52% of initial yield was maintained for 200 hr. New structured-oligosaccharides (NOS) reduced the change of pH in the culture of Streptococcus mutans. It also showed an inhibitory effect on the growth of Staphylococcus aureus.

• Journal of Information Processing Systems
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• v.15 no.3
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• pp.464-477
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• 2019

With the sustained and rapid development of new energy sources, the demand for electric energy is increasing day by day. However, China's energy distribution is not balanced, and the construction of transmission lines is in a serious lag behind the improvement of generating capacity. So there is an urgent need to increase the utilization of transmission capacity. The transmission capacity is mainly limited by the maximum allowable operating temperature of conductor. At present, the evaluation of transmission capacity mostly adopts the static thermal rating (STR) method under severe environment. Dynamic thermal rating (DTR) technique can improve the utilization of transmission capacity to a certain extent. In this paper, the meteorological parameters affecting the conductor temperature are analyzed with the IEEE standard thermal equivalent equation of overhead transmission lines, and the real load capacity of 220 kV transmission line is calculated with 7-year actual meteorological data in Weihai. Finally, the thermal load capacity of DTR relative to STR under given confidence is analyzed. By identifying the key parameters that affect the thermal rating and analyzing the relevant environmental parameters that affect the conductor temperature, this paper provides a theoretical basis for the wind power grid integration and grid intelligence. The results show that the thermal load potential of transmission lines can be effectively excavated by DTR, which provides a theoretical basis for improving the absorptive capacity of power grid.

• Analytical Science and Technology
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• v.32 no.4
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• pp.155-162
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• 2019

Analysis techniques using DNA profiling are widely used in various fields including forensic science and new technologies such as the Direct PCR amplification method are being developed continuously in order to acquire the DNA profiles efficiently. However, it has a limits such as non-specific amplification according to the quality of crime scene evidence samples. Especially, split peaks caused by excessive DNA samples are one of the important factors that could cause the debate to allow researchers to interpret the DNA profile results. In this study, we confirmed the occurrence rate of split peaks in each STR (short tandem repeats) locus of the $GlobalFiler^{TM}$ kit and investigated the possibility of improving the split peaks using several PCR additives such as DMSO (dimethylsulfoxide), $MgCl_2$, Betaine and Tween-20. As a result, we could make three groups according to the occurrence rate of split peaks in Direct PCR and it was confirmed that the ratio of split peaks could be reduced by DMSO (87.4 %), $MgCl_2$ (84.5 %) and Betaine (86.1 %), respectively. These results indicate that PCR additives such as DMSO, $MgCl_2$ and Betaine can be improve the split peaks in Direct PCR and thereby facilitate subsequently a successful DNA profile results.