• The Journal of the Acoustical Society of Korea
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• v.23 no.2
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• pp.162-172
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• 2004

This study investigates the following three things through a production experiment and acoustic analysis: 1) relationship between speech rate and the segment duration in Korean, 2) relationship between speech rate and spectral characteristics of vowels, i. e. undershoot, and 3) correlation between the vowel duration and undershoot. The results showed that the faster the speech rate nab, the shorter the duration of syllables and segments was. A few speakers were affected by speech rate in the durational ratios between closure and aspiration in a stop and between Towel and consonant in a syllable. Closure duration and vowel duration were more affected compared to aspiration and consonant duration, respectively. Speakers showed some differences in the extent to which speech rate affected vowel undershoot, implying that speakers used different production mechanisms for spectral characteristics of vowels: Some speakers speeded up movement of articulatory organs according to speech rate increase while some kept it constant regardless of speech rate change.

• Journal of Oriental Neuropsychiatry
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• v.17 no.1
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• pp.59-78
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• 2006

Objective : This research investigates the effect of the CMT and SCMT on Alzheimer's disease. Methods : The effects of the CMT and SCMT on (1) amyloid precursor proteins(APP), acetylcholinesterase(AChE) mRNA of PC-12 cells treated with CT-105; (2) the AChE activity and the APP production of PC-12 cell treated with CT-105; (3) the behavior; (4) expression of $IL-1{\beta}$, $TNF-{\alpha}$, MDA; (5) the infarction area of the hippocampus in Alzheimer's disease mice induced with CT105 & ${\beta}A$ were investigated Rresults : 1. The CMT and SCMT suppressed the expression of APP, AChE mRNA in PC-12 cells treated with CT-105 2. The CMT and SCMT suppressed the AChE activity, and the production of APP significantly in PC-12 cells treated with CT-105. 3. For the CMT and SCMT group a significant inhibitory effect on the memory deficit was shown for the mice with Alzheimer's disease induced by ${\beta}A$ in the Morris water maze experiment, which measured stop-through latency, and distance movement-through latency 4. The CMT and SCMT suppressed the over-expression of $IL-1{\beta}$, $TNF-{\alpha}$, MDA in the mice with Alzheimer's disease induced by ${\beta}A$. 5. The CMT and SCMT reduced the infarction area of hippocampus with Alzheimer's disease induced by ${\beta}A$. Conclusions : These results suggest that the CMT and SCMT may be effective for the prevention and treatment of Alzheimer's disease. Investigation into the clinical use of the CMT and SCMT for Alzheimer's disease is suggested for future research.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.1
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• pp.33-38
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• 2004

This study was aimed at testing the gene expression of antioxidant enzymes and apoptosis genes for in vitro culture in porcine embryos produced by in vitro maturation/in vitro fertilization (IVM/IVF). Pocine preimplantation embryos obtainted from IVM/IVF can be successfully culture in vitro, but they are delayed or stop to develop at specific developmental stage. Many factors such as reactive oxygen species and apoptosis in an IVM/IVF system followed by in vitro culture influence the rate of production of viable blastocysts. Porcine embryos derived from IVM/IVF were cultured in the atmosphere of 5% $CO_2$ and 20% $O_2$ at $38.5^{\circ}C$ in NCSU23 medium. The patterns of gene expression for antioxidant enzymes and apoptosis genes during in vitro culture in pocine IVM/IVF embryos were examined by the modified semi-quantitative single cell reverse transcriptase-polymerase chain reaction (RT-PCR). Porcine embryos produced by in vitro procedures were expressed mRNAs for CuZn-SOD, GAPDH and GPX, whereas transcripts for Mn-SOD and catalase were not detected at any developmental stages. Expression of caspase-3 mRNA was detected at 2 cell, 8 cell 16 cell and blastocyst, but p53 mRNA was not detected at any stages. The fas transcripts was only detected in blastocyst stage. These results suggest that various antioxidant enzymes and apoptosis genes play crucial roles in vitro culture of porcine IVM/IVF embryos.

• Journal of the Korean Society for Railway
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• v.18 no.4
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• pp.391-400
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• 2015

This research used a survey of 350 staff members working at Korail with the purpose of analyzing influence factors for the railway tourism policy for job satisfaction; results were presented for the proposed factor. First, we selected the influence factor through precedent research related to the railway tourism policy. Second, the selected influence factor and the extent of satisfaction were used to determine whether or not any kind of difference existed according to individual attributes of the railway employees. Finally, we analyzed what the influence factor was between the category factor and the sub-category factor. In conclusion, it was found that government subsidy had a meaningful correlation with infrastructure expansion and the improvement of the railway business as it is connected to tourism efficiency. Human resources have a meaningful correlation with the needs of educational institutions and the retaining of talent. Railway tourism production has a meaningful correlation with railway tour production as it is conducted to satisfy tourists and the consortium. The shift of viewpoint has a meaningful correlation with the escape from the peace-at-any price principle and demand forecasting.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1658-1663
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• 2006

Panax notoginseng (Buck) F.H chen. root (PNS) is used as a therapeutic agent to stop haemorrhages and a tonic to promote health in Korean and Chinses medicine. The pharmacokinetic profiles of the main PNS are still not accurately investigated. Our preliminary aim is to elucidate the pharmacokinetics features of the PNS in rats. Objective of this study is to determine whether PNS affects hepatic microvascular dysfunction elicited by gut ischemia and reperfusion (I/R), since gut I/R causes hepatic microvascular dysfunction, and to investigate the role of nitric oxide (NO). No has been found to be a modulator of the adhesive interactions between platelet and endothelial cells. Male Wistar rats were exposed to 30 min of gut ischemia followed by 60 min of reperfusion. Intravital microscopy was used to monitor the number of non-perfused sinusoids (NPS). In another set of experiments, PNS (1 g/kg pre day intragastrically) was administered to rats for 7 days. In some experiments, dexamethasone (ST) (2 mg/kg per day intravenously) was administered. In control rats, gut I/R elicited increases in the number of NPS, and plasma TNF-${\alpha}$ and ALT activities, and these changes were mitigated by the pretreatment with PNS. Pretreatment with an No synthase inhibitor diminished the protective effects of PNS on the increase in NPS and plasma TNF-${\alpha}$ levels, but not its effect on the increase in plasma ALT activities. Pretreatment with PNS increased plasma nitrite/nitrate levels. The responses caused by gut I/R were attenuated by the pretreatment with ST. Pretreatment with an NO synthase inhibitor did not affect the effect of ST. These results suggest that PNS attenuates the gut I/R-induced hepatic microvascular dysfunction and inflammatory responses such as TNF-${\alpha}$ production in the early phase via enhancement of NO production, and sequential hepatocellular damage via its anti-inflammatory effect like corticosteroid effect.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.53 no.3
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• pp.276-285
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• 2017

The research vessel NARA equipped with an azimuth thruster system was built in 2015. There are few vessels with this propulsion system in Korea. This vessel has two modes such as the normal for maneuvering and the power for investigation, and the other two modes as one axis and two axes on the operating. This type of vessels does not seem to have a clear grasp of the maneuvering character in comparison with the vessel with a conventional propulsion system. So the authors carried out the sea test for the turning, the zigzag and the inclination, and the results are as follows. In turning test, the case of using the two axes mode is much better than the case of using the one axis mode for the elements of turning, such as advance, transfer, tactical diameter and final diameter, but turning hard over the rudder in full speed is very vulnerable to capsize in both modes. In zigzag test, the yaw quicking responsibility index, T is very large excessively, which means a bad counter maneuvering ability, so an operator has to keep in mind that in turning operation. If necessary to avoid collision at head on situation, it may be a more effective method to use the crash astern stop than the turning according to the conditions and circumstances for the shortest stopping distance is very short.

• Food Science of Animal Resources
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• v.41 no.1
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• pp.16-33
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• 2021

To stop hunger, reducing food losses is a potential movement towards saving food. A large portion of these losses could be avoided and reduced through the improved food chain in many countries. Raising awareness on how and where food losses occur will help recovering foods such as meat by identifying solutions and convincing people to implement those solutions. This, in turn, will lead to private and public efforts to recover meat that might be otherwise wasted. After highlighting the importance of food saving benefits and relevant statistics, this paper explains the possible ways to reduce meat loss and waste in abattoirs and presents a framework for prevention according to the estimates of meat losses in Iran meat supply. The current article answers the questions of where do we have the meat loss in Iran and what approaches are most successful in reducing losses in the meat industry. The national average loss and waste in meat production are about 300,000 metric tonnes (about 15%). Many segments and players are involved with this huge amount of losses in the meat value chain, a large portion of these losses could be avoided and reduced by about 25% through using by-products with the mechanization of design and manufacturing. The production amount of mechanically deboned meat (MDM) is 105,091,000 kg, concluding the major waste (88.33%) of total poultry losses. Ensuring appropriate actions by exploiting the full potential of engaged Iranian associations and institutes is considered to reduce the losses.

• The Korea Journal of Herbology
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• v.28 no.1
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• pp.9-14
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• 2013

Objectives： Bletillae Rhizoma, the roots of Bletilla striata, is used to restrain the leakage of blood and stop bleeding. It can cure the sores, ulcers, and chapped skin. This study was designed to investigate the collagen metabolism, elastase and tyrosinase activity of Bletillae Rhizoma extract (BR). Methods : The effects of BR on type I procollagen production and collagenase activity in human normal fibroblasts Hs68 after UVB (312 nm) irradiation were measured by ELISA method. The elastase activity, tyrosinase activity, and L-DOPA oxidation after treatment of BR were measured as well. Results : In the present study, the collagen production (type I procollagen) was significantly increased to $15.7{\pm}1.8$ ng/ml at a concentration of BR 100 ${\mu}g/ml$ in UVB damaged Hs68 cells. The increased collagenase activity after UVB damage was significantly recovered to $42.7{\pm}0.7%$, $54.5{\pm}3.5%$, and $38.4{\pm}0.9%$ by BR 10, 30, and 100 ${\mu}g/ml$. The activities of BR 10 mg/ml on tyrosinase activity was significantly reduced to $45.1{\pm}8.4%$ as well. However, there were no significant effects on the elastase activity and the L-DOPA oxidation. Conclusion : BR showed the promoting effects of collagen synthesis and inhibitory effects of collagenase activity in Hs68, human normal fibroblast cells. And these could be thought to have the anti-wrinkle effects and whitening effects in vitro. These results suggest that BR may have potential as an anti-aging ingredient in cosmetic treatment.

• Journal of Korea Port Economic Association
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• v.20 no.1
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• pp.123-140
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• 2004

With the globalization of economy, there is keen competition among rountries to be a logistics hub and companies are striving to be first in establishing logistics system centering on advantageous sites, especially airport and seaports, to perform supply, production and distribution. Korea competing with Northeast Asia countries is also working out strategies in order to make Korea peninsula a logistics center of Northeast Asia taking advantage of its geographical strength. Gwangyang port has designated as Free Economic Zone together with Pusan and Jinhae, Incheon from October 24th, 2003. However, the introduction of Free Economic Zone in Korea lagged behind other major countries and it has a lot of operational problems. Approximately 600 areas worldwide are designated and operated as a Free Economic Zone and Gwangyang port and its surrounding area has several points to be settled as one of FEZ. First one is its limited functions and related laws. Next is imperfection on development, investment and management system of the hinterland. Lark of promotion activities could be one of the problems. This paper analyzes the above problems and presents various measures to activate Gwangyang Port and Gwangyang Free Economic Zone as follows Benchmarking to promote Gwangyang Free Economic Zone as follows Benchmarking other countries' system, governmental support, introduction & logistics functions, early development of the hinterland, supply of effective one-stop service, investment attraction into the area and diversified promotion & marketing activities.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2005.05a
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• pp.125-131
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• 2005

Recently, to improve condition car park, using surface finishing material for variety color and property epoxy resin, urethane, cement mixed resin mortar or polymeric resin, and so on. However, it is frequent noise and wear out of tier and waterproofing materials, when the car slip or stop in car park, To minimize these cases, It is necessary that reduction of repair cost through performance long term durability of surface finishing material, improvement inside condition such as reduce dirty and car accident and ensurance the expected life of concrete slab in car park. Especially, we have not any tech for quality control, construction tech, production technology for car park surface materials, that's why park slab is not safety and suffer a loss. For this problems, this paper is to test surface finishing materials and as that result, suggest quality standard in the car park.