• The Journal of Korean Physical Therapy
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• 제18권3호
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• pp.9-21
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• 2006

Purpose: This study was intended to examine the effects of electroacupuncture and therapeutic exercise on muscle atrophy and exercise function in an ischemic stroke model induced by middle cerebral artery occlusion. Methods: This study selected 120 Sprangue-Dawley rats, 8-week of age, divided them into six groups, and assigned 5 rats to each group. Experiments were conducted for 1, 3 days, 1, and 8 weeks, respectively. Group I was a group of electroacupuncture and therapeutic exercise after inducing ischemic stroke; Group II was a group of therapeutic exercise after inducing ischemic stroke; Group III was a group of electroacupuncture after inducing ischemic stroke; Group IV was a sham group of electroacupuncture after inducing ischemic stroke; Group V was a control group and Group VI was a sham group without ischemic stroke. In each group, changes in weight of muscle and relative muscle of TA muscle, neurologic motor behavior test, histologic observations were observed and analyzed. Results: For the changes in muscle weight of unaffected and affected sides of TA muscle, muscle atrophy was seen in an affected side 3 days after ischemic stroke was induced. There was statistically significant difference in Group I 1 week and 8 weeks after ischemic stroke was induced, compared to Group V (p<0.05). For the changes in relative muscle weight of unaffected and affected sides of tibial anterior muscle, there was significant decrease in each group 3 days after ischemic stroke was induced, compared to Group IV, while there was statistically significant increase in Group I 1 week after ischemic stroke was induced, compared to Group V (p<0.05). For neuologic exercise behavior test, Group I generally had the highest score, compared to other groups. Conclusion: electroacupuncture and therapeutic exercise may improve muscle atrophy and change in histologic observations expression of ischemic stroke rats and contribute to the improvement of exercise function.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 춘계학술대회논문집
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• pp.1062-1073
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• 2007

Acoustic Target Strength (TS) is a major parameter of the active sonar equation, which indicates the ratio of the radiated intensity from the source to the re-radiated intensity by a target. In developing a TS equation, it is assumed that the radiated pressure is known and the re-radiated intensity is unknown. This research provides a TS equation for polygonal plates, which is applicable to near field acoustics. In this research, Helmholtz-Kirchhoff formula is used as the primary equation for solving the re-radiated pressure field; the primary equation contains a surface (double) integral representation. The double integral representation can be reduced to a closed form, which involves only a line (single) integral representation of the boundary of the surface area by applying Stoke's theorem. Use of such line integral representations can reduce the cost of numerical calculation. Also Kirchhoff approximation is used to solve the surface values such as pressure and particle velocity. Finally, a generalized definition of Sonar Cross Section (SCS) that is applicable to near field is suggested. The TS equation for polygonal plates in near field is developed using the three prescribed statements; the redection to line integral representation, Kirchhoff approximation and a generalized definition of SCS. The equation developed in this research is applicable to near field, and therefore, no approximations are allowed except the Kirchhoff approximation. However, examinations with various types of models for reliability show that the equation has good performance in its applications. To analyze a general shape of model, a submarine type model was selected and successfully analyzed.

• 대한한방내과학회지
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• 제30권4호
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• pp.799-805
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• 2009

Objectives : This study was aimed to assess characteristics in acute stroke patients according to abdominal obesity. Method : 1,506 subjects were included from the patients admitted to the Internal Medical Department at Kyunghee University Oriental Medical Center, Kyunghee University East-West Neo Medical Center, Kyungwon University Songpa Oriental Medical Center, Kyungwon University Incheon Oriental Medical Center, and D ongguk University Ilsan Oriental Medical Center from April 2007 to August 2009. Results : 1. Considering the demographic variables of the patients, the gender, older age, diabetes, hyperlipidemia and multiple infarction were significantly higher in the abdominal obesity group than in the control group. 2. Sasang constitution and oriental medical diagnosis showed significant difference in the abdominal obesity group. By oriental medical diagnosis, the D amp ness-Phlegm group was significantly higher in abdominal obesity group than in the control group. According to this analysis, we observed the general disposition of various characteristic distributions according to abdominal obesity in acute stoke patients These results can be utilized in the future as a basis material.

• 동의생리병리학회지
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• 제18권2호
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• pp.586-595
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• 2004

Kamidojuk-San (KDJS) is known to be effective for treating cardiovascular diseases such hypertension, and clinically applied for the treatment of cerebral palsy or stoke patients. Yet, the overall mechanisms underlying its activity at the cellular levels are not known. Using experimental animal system, we investigated whether KDJS has protective effects on cells in cardiovascular and nervous systems. KDJS was found to rescue death of cultured primary neurons induced by AMPA, NMDA and kainate as well as BSO and Fe/sup 2+/ treatments. Moreover, KDJS treatment promoted animal's recovery from coma induced by a lethal dose of KCN treatment, and improved survival in animals exposed to lethal dose of KCN. Neurological examinations further showed that KDJS reduced the time which is required for animals to respond in terms of forelimb and hindlimb movements. To examine its physiological effects on cardiovascular and nervous systems, we induced ischemic injury in hippocampal neurons and cerebral neurons by middle cerebral artery (MCA) occlusion. Histological examination revealed that KDJS significantly protected neurons from ischemic damage. Thus, the present data suggest that KDJS may play an important role in protecting cells of cardiovascular and nervous systems from external noxious stimulations.

• 한국방재학회:학술대회논문집
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• 한국방재학회 2011년도 정기 학술발표대회
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• pp.69-69
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• 2011

본 논문에서는 비정상 상태의 비압축성 유동장을 해석하기 위하여 물체맞춤격자방법이 아닌 가상경계법을 사용하였다. 가상경계법은 구조격자를 사용하여 구조물 경계면에서 Momentum Forceing을 사용하여 가상의 경계를 만들어 유동장을 해석하는 방법이다. Navier-Stoke 방정식의 수치 이산화 방법으로 Kim et al(1985)이 사용한 Fractional Step Method(FSM)을 사용하였다. 시간에 대하여 semi-implicit FSM를 사용하였고, 확산항에 대해서는 2차 정확도의 Crank-Nicolson Method를 대류항은 3차 정확도의 Runge-Kutta Method를 사용 하였다. 본 연구에서는 가상경계법을 이용한 유동장 해석이 교량 단면에 대하여 수치해석이 가능한지 검토하였다. 가상경계법은 현재 많은 연구가 유선형의 구조물에 대하여 수행되어 오고 있다. 교량 단면과 같은 각 진 구조물에 대한 검토는 아직 미비한 실정이다. 가상경계법에서 다루고 있는 구조물 경계면에서의 Momentum Forcing 방법이 유선형의 구조물에 맞추어 연구가 진행되었기 때문이다. 먼저 본 연구의 프로그램을 검증하기 위하여 원형 실린더에 대하여 가상경계법을 적용한 결과 Re 수 200에서 Strouhal Number, 양력계수, 항력계수를 이전 연구 결과와 비교하였다. Williamson(1988)과 Zhang(1995)의 연구결과와 유사한 결과를 얻을 수 있다. 그리고 교량의 단면과 같은 각진 구조물(Bluff Body)에 대하여 가상경계법 적용하였다. 본 논문의 연구에서 평가 대상으로 하고 있는 2차원 교량 단면에 대하여 유동장 해석을 하였다. 본 논문에서 정량적인 유체력과 유동장에 대한 비교 및 검토가 이루어지지 못했지만 압력장과 유선의 형태가 이론적인 값을 벗어나지 않고 있는 것으로 확인 되었다. Re 수 2700에서 전산 해석을 수행하였으며, 교량 단면 주위의 압력계수와 박리현상 그리고 후류에서의 Vortex shedding 현상이 모두 적절한 분포가 나타나는 것을 확인할 수 있었다. 따라서 가상경계법을 이용하여 각진 구조물에 대한 주위 유동장해석에 대한 가능성을 확인하였으며, 풍동실험과의 결과비교를 통하여 가상경계법을 이용하여 교량 단면 주위의 유동장 해석 결과를 정량적으로 비교할 것이다.

• 성인간호학회지
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• 제12권1호
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• pp.147-162
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• 2000

Predicting factors of post-stroke depression were investigated. The subjects were 254 stroke patients who had been discharged and visited regularly the outpatient clinic for follow up care. The influencing factors were classified into five categories : demographic, disease-related, current state, social support, and illness intrusiveness. Sex, age, job, and educational level were defined as the demographic factor. The disease-related factors included stroke type, illness duration, attack frequency, and NIH score. ADL, cognitive function, and social activity were considered as the current state factors. The social support was measured as the perceived amount of social support. Illness intrusiveness means the perceived illness induced life style disruptions. Demographic, disease-related, current state, and social support were hypothesized to directly and indirectly affect post-stroke depression through illness intrusiveness. The illness intrusiveness was hypothesized to directly affect post-stroke depression. The hierarchial multiple regression was used to identify significant factors. The result showed that this model explained 43.3% of variance of post-stroke depression. And the prevalence of post-stroke depression was 38.8%. Among the demographic factors, job was identified as a main contributor to indirectly increase the post-stroke depression. Among the disease-related factors, stroke type, attack frequency, and NIH score were found to indirectly affect the post-stroke depression. Among the current state factors, ADL and social activity indirectly affected the post-stroke depression through illness intrusiveness. Social support and illness intrusiveness were identified to directly affect the post-stroke depression. This study has proved the factors likely to be implicated in the development of post-stroke depression. Based upon these results, it is recommended that the nurses who take care of post-stroke patients consider the risk factors such as social support, illness intrusiveness et al. Also programs which decrease the illness intrusiveness and increase the social support to reduce post-stoke depression recommended to be developed.

• 대한토목학회논문집
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• 제36권5호
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• pp.819-830
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• 2016

아직까지 밀도성층을 통과하는 파랑변형에 관한 동수학적 특성에 대해서 명확히 밝혀진 부분은 그다지 많지 않다. 따라서 본 연구에서는 2층 밀도성층을 통과하는 파랑의 수리특성을 수치적으로 해석하기 위하여 온도와 염분에 따른 밀도류를 해석할 수 있게 개량된 3차원 수치파동수조(LES-WASS-3D ver. 2.0)를 이용하여 수치시뮬레이션을 수행하였다. 그리고 이용하는 수치파동수조의 타당성 및 유효성을 확인하기 위하여 Stokes 3차 파랑이론에 근거한 내부파형을 비교 검토하였다. 수치시뮬레이션 결과로부터 밀도성층을 통과하는 수면파 및 내부파의 파고가 감소하는 현상을 알 수 있었으며, 이것은 상 하층의 밀도차이에 기인한 전파속도 차이로 인하여 계면에서 강한 와도가 발생하기 때문으로 확인되었다. 또한 밀도성층의 밀도차이가 증가할수록, 상 하층의 수심비가 증가할수록(상층의 수심이 깊어질수록) 와도가 강하게 발생하여 수면파 및 내부파의 파고감쇠를 심화시키는 것을 확인할 수 있었다.

• 대한한방내과학회지
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• 제19권2호
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• pp.50-59
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• 1998

Background : Vascular dementia occurs mainly due to cerebral vascular disease. So we performed this clinical study to investigate the incidence and characteristics of vascular dementia in stroke patients. Methods : This study was performed on the patients hospitalized from April 1, 1998 to August 31, 1998 at the department of circulatory internal medicine, hospital of Oriental medicine, Kyung-Hee University, and diagnosed cerebral infarction or hemorrhage by Brain CT or MRI. we devided the patients into two groups; vascular dementia group and non dementia group according to MMSE-K(Mini Mental State Examination Korean version), Hasegawa dementia scale. Patients were diagnosed dementia using DSM-IV. We compared general characteristics, stoke types and laboratory findings between the two groups and investigated the correlationship between MMSE-K and Hasegawa dementia scale. Results : Results showed that the incidence of vascular dementia was about 27.8% in stroke patients. The greater number of subjects with dementia were women in the lower educational classes and had lower MBI(Moderfied Bathel Index) scores. Vascular dementia were more common in patients with large brain lesion size($>20cm^3$). There was a positive correlationship between Hasegawa scores and MMSE-K.

• 대한한의학회지
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• 제27권1호
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• pp.118-129
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• 2006

Objectives : A human being is classified into 4 constitutions(Taeyangin, Soyangin, Taeumin, and Souemin) and each constitution has the different incidence, treatment and prevention of disease in Sasang Constutional Medicine[SCM], The purpose of this study is to find relative risk(RR)s of each risk factors including Sasang Constitution[SC] for incidence of ischemic stroke. Methods : In 344-case patients with ischemic stroke and 1446 healthy control subjects without ischemic stroke, we evaluated sex, age. height, weight, BMI, ECG abnormality, hypertension, diabetes mellitus, blood lipid level and SC. These data were statistically analysed to investigate the relations between risk factors and the incidence of ischemic stroke by chi-square test. And then significant factors were analysed to get each adjusted odds ratio[OR] by binary logistic regression analysis. Results : ECG abnormality, hypertension, diabetes mellitus, HDL(high density lipoprotein) cholesterol, and SC were significantly related to the incidence of ischemic stroke, while age, sex and BMI were adjusted in a binary logistic regression analysis. Especially in SC, the incidence of ischemic stoke in Tae-eumin and Soyangin were higher than that in Soeumin (Tae-eumin OR=11.68[95% CI: 6.26-21.80], Soyangin OR=4.64[95% CI: 2.66-8.10]). Conclusions : These results suggested that SC may be one of important risk factors for ischemic stroke and it should be a useful data for prediction of incidence of ischemic stroke.

• 대한한방내과학회지
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• 제37권6호
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• pp.990-997
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• 2016

Objectives: This study observed changes in gait pattern according to the motor grade of the paretic lower limb in patients with basal ganglia stroke who are in the subacute phase. Methods: We used the Manual Muscle Test (MMT) to evaluate the motor grade of the paretic lower limb of 21 patients with subacute basal ganglia stroke and then divided them into two groups based on the MMT results. Stroke patients with a motor grade above Gr. III were put in group I (15 people) and those with a grade less than Gr. III in group II (6 people). We also estimated spatiotemporal factors using treadmill gait analysis equipment. The values were gait velocity, step length, step time, double support phase, and cadence. The first measure was conducted during the early period of admission and the second was between four and five weeks after admission. Results: In Group I, the gait velocity and step length of both legs significantly increased. In Group II, the step length and step time of the paretic side and the gait velocity tended to decrease, but not significantly. The step length of the paretic side in Group II was significantly longer than that in Group I at the first measure. The step time of the paretic side in Group I was significantly shorter than that in Group II and gait velocity and cadence in Group I were significantly higher than in Group II at the second measure. Conclusions: The gait parameters of all stroke patients improved in terms of time. In addition, the changes in gait pattern were different depending on the motor grade of the paretic lower limb.