• The Journal of Korean Physical Therapy
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• v.14 no.1
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• pp.55-62
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• 2002

The purpose of this study was to determine the effects of the ultrasound on treatment of chronic sinusitis. 24 persons of men and women with chronic sinusitis divided into three groups of each 8 persons randomly and when were they were treated with the medication, the ultrasound(1MHz continuous wave, 1W/$cm^2$ intensity, three times per a week and once of three minutes circular stroke method) and the medication+ultrasound for 2, 4, 6 and 8 weeks. The results of this study were ad follows. 1. There was not statistical significant differences between the effects of treatment until two weeks(P>.05). 2. There was statistical difference between the effects of treatment after 4 weeks, 6 weeks and 8 weeks(P<.05). There was statistical significant difference between the group with ultrasound treatment and the group with ultrasound+medication treatment and there was statistical significant difference between the group with medication treatment and the group with ultrasound+medication treatment but there was not statistical significant between the group with ultrasound treatment and the group with medication treatment. 3. After 4 weeks, the highest effect for chronic sinusitis was group

• Journal of Korean Society of Water and Wastewater
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• v.20 no.2
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• pp.281-287
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• 2006

Maintaining adequate chlorine residual is crucial in water treatment facilities, Treatment technique, newly promulgated regulation, requires sufficient disinfection in order to control more resistant microorganisms such as Viruses and Giardia lamblia. Each water treatment plant should report various water qualities including chlorine residual and disinfection by-products, thus plenty of data has been generated. Even though statistical analysis using these data are forced to investigate the status and effect of water qualities in water facilities very few researches have been performed in korea. This study performed statistical analysis of chlorine residual during three years in Korean drinking water. The average chlorine residual concentrations were 0.701mg/L, 0.738mg/L, 0.763mg/L in 2002, 2003, 2004, respectively. Monthly variations of chlorine residual was not significant. ANOVA result showed that yearly variance of chlorine residual is different in only less than $5000m^3/day$ of water treatment capacity. The statistical analysis can help government to establish new regulation with scientific basis.

• The Journal of Korean Physical Therapy
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• v.14 no.1
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• pp.15-26
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• 2002

The purpose of this study was to find the effects of scapular pattern and hold-relax technique of propriocetive neuromuscular facilitation(PNF) on the range of motion(ROM) and to find the effects of pain relieve through visual analogue scale(VAS) in frozen shoulder patients. The subjects were consisted of thirty frozen shoulder patients(men ; 9, women ; 21). The measurement of the shoulder range of motion was taken by measuring the degrees of flexion, abduction, and external rotation with a goniometer and the measurement of pain was performed by VAS from pre treatment to one to four weeks The results were as follows : 1. There was the statistical significance not only in the range of motion such as shoulder flexion, abduction, and external rotation, but also in VAS during four weeks(p<.05). 2. By the result of Scheffe's multiple comparison test. there was statistical significance between the values of pre treatment and treatment after one week in the range of motion of shoulder flexion. In that of shoulder external rotation, there was statistical significance between the values of pre treatment and treatment after one week, and between those of treatment after one and two weeks. As the result of this statistical significance of shoulder external rotation, the early treatment was thought to be more effective. However, there was statistical significance in the treatment after two and three weeks in shoulder abduction and was statistical significance between the values of pre treatment and the treatment after one weeks, and between those of treatment after two and three weeks in VAS (p<.05). 3. There was not statistical significance between men and women in the range of motion of the shoulder and in VAS(p>.05). 4. There not statistical significance between th right and left frozen shoulder patients in the range of motion of shoulder and in VAS(p>.05).

• Communications for Statistical Applications and Methods
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• v.25 no.4
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• pp.341-354
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• 2018

The one of the principles described in ICH E9 is that only results obtained from pre-specified statistical methods in a protocol are regarded as confirmatory evidence. However, in multi-regional clinical trials, even when results obtained from pre-specified statistical methods in protocol are significant, it does not guarantee that the test treatment is approved by regional regulatory agencies. In other words, there is no so-called global approval, and each regional regulatory agency makes its own decision in the face of the same set of data from a multi-regional clinical trial. Under this situation, there are two natural methods a regional regulatory agency can use to estimate the treatment effect in a particular region. The first method is to use the overall treatment estimate, which is to extrapolate the overall result to the region of interest. The second method is to use regional treatment estimate. If the treatment effect is completely identical across all regions, it is obvious that the overall treatment estimator is more efficient than the regional treatment estimator. However, it is not possible to confirm statistically that the treatment effect is completely identical in all regions. Furthermore, some magnitude of regional differences within the range of clinical relevance may naturally exist for various reasons due to, for instance, intrinsic and extrinsic factors. Nevertheless, if the magnitude of regional differences is relatively small, a conventional method to estimate the treatment effect in the region of interest is to extrapolate the overall result to that region. The purpose of this paper is to investigate the effects produced by this type of extrapolation via estimations, followed by hypothesis testing of the treatment effect in the region of interest. This paper is written from the viewpoint of regional regulatory agencies.

• The Korean Journal of Applied Statistics
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• v.25 no.4
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• pp.575-587
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• 2012

The effect of a new treatment is proven through the comparison of a new treatment with placebo; however, the number of parent non-inferiority trials tends to grow proportionally to the number of active controls. In a non-inferiority trial a new treatment is approved by proof that the new treatment is not inferior to an active control; however, both additional assumptions and historical trials are needed to show (through the comparison of the new treatment with the active control in a non-inferiority trial) that the new treatment is more efficacious than a putative placebo. The two different methods of using the historical data: frequentist principle method and meta-analytic method. This paper discusses the statistical methods and different Type I error rates obtained through the different methods employed.

• Journal of the Korean Statistical Society
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• v.26 no.1
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• pp.89-100
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• 1997

In this paper we are concerned with comparing ordered treatment effects with a control in a randomized block design with multiple observations per cell. Two nonparametric procedures for detecting which treatment are better than the control are proposed and compared. An example is given and the results of a Monte Carlo power study are discussed.

• The Journal of Korean Physical Therapy
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• v.16 no.3
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• pp.125-141
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• 2004

The purpose of this study was to assess the effectiveness of myofascial release(MFR) technique and Taping therapy on the pain level in whiplash injury patients. Pain level were assessed prior treatment, after first treatment, after second treatment, after third treatment, after fourth treatment, and after fifth treatment. All 6 times were calculated pain level. To find out the effectiveness of MFR and Taping therapy, we were divide two groups. The one group was consisted of 25 patients that were treated with H/P, electrical therapy and MFR, and the other group was consisted of 25 patients that were treated with H/P, electrical therapy, and Taping therapy. The results were as follow: 1. There were statistical significance on the pain level in MFR group during all treatment periods(p<0.05). 2. There were statistical significance on the pain level in Taping group all during treatment periods(p<0.05). 3. Taping group had more statistical significance than MFR group on the pain level during all treatment periods(p<0.05). Consequently, this study suggest that Taping therapy has a very effectiveness to the whiplash injury patients.

• The Journal of Korean Physical Therapy
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• v.16 no.1
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• pp.124-139
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• 2004

Taping treatment is frequently used in the management of musculoskeletal pain The purpose of this study was to assess the effectiveness of ultrasound and taping treatment on the pain and grip strength with lateral epicondylitis. Pain and grip strength were assessed prior, after first, after second, after third, after fourth, and after fifth treatment. All 6 times calculated pain and grip strength. To find out the effectiveness of taping treatment, we were divide two groups. the one group was consisted of 20 patients that treated with H/P, electrical therapy and ultrasound, and the other group was consisted of 20 patients that treated with H/P, electrical therapy and taping. The results were as follow: 1. There were statistical significance on the pain and grip strength with ultrasound group(P<0.05). 2. There were statistical significance on the pain and grip strength with taping group(P<0.05). 3. Taping group was more statistical significance than ultrasound group on the pain(P<0.05). 4. There was no statistical significance between ultrasound group and taping group on the grip strength(P>0.05).

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.24 no.3
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• pp.108-118
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• 2011

Objective : This study was designed to evaluate the influence of time from onset of Bell's palsy until commenced Oriental medicine therapy on Bell's palsy. Methods : We investigated 35 cases of patients with peripheral facial palsy who visited Wonkwang University Oriental Hospital from 10th, December 2010 to 31st August, 2011 and classified them as time from onset of Bell's palsy until commenced Oriental medicine therapy. Time from onset of Bell's palsy until commenced Oriental medicine therapy of Group A was within 3 days. Group B was from 4 days to 8 days. We evaluate the treatment effect of each group by House-Brackmann grade before treatment and 1,3 week treatment. Results : 1. There was a statistical difference in period from onset of Bell's palsy until commenced Oriental medicine therapy between Group A and Group B. 2. There was a statistical difference after 1 week treatment in Group B. 3. There was a statistical difference after 3 weeks treatment in both Group A and B.3. After 3 week treatment, there was statistical significant difference in decreased value of House-Brackmann grade between Group A and Group B. Group A showed more recovery compared with Group B. Conclusions : 1. These results suggest that early oriental medicine treatment could be more effective in recovery of Bell's palsy. 2. Further studies will be required to identify the beneficial effect of early oriental medicine treatment in bell's palsy.

• Journal of Korean Physical Therapy Science
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• v.9 no.1
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• pp.45-52
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• 2002

This study was intended to observe the relationship of pain alleviation between the group with needle electrode electrical stimulation applied on bach of head, lung, nasalis internae, shen-men, pharynx & larynx, and internal secretion which are the pants to regulate smoking and that, with no treatment of the kind among smokers and con-smokers with chronic low back pain. It also aimed to conduct a research of applying different treatment methods according to smoking, thus ultimately providing basic data needed by clinic therapists and to help achieve appropriate treatment effects considering the characteristics of each patient. The subject criteria were men who were in their 40's or 50's, smoking or non-smoking and came to the physical therapy of the hospital to cure the chronic low back pain which had lasted more than three months. The total 24 subjects were randomly divided into four groups according to smoking; the group of smokers with needle electrode electrical stimulation applied, that of smokers with no application of such treatment, that of non-smokers with the action of such treatment, and that of non-smokers with no application of such treatment Each group was measured in terms of four pain assessment methods of visual analogue scale(VAS), verbal rating scale(VRS), McGil pain questionnaire(MPQ), endorphin. And the results were as follows: 1. In terms of the effects of the needle electrode electrical stimulation in the auricular therapy on pain had by the smokers with low back pain, there was a statistical significance in VAS, VRS, and endorphin 1 between before and after the treatment. 2. In terms of the pain effects had by the smokers with low back pain when no needle electrode electrical stimulation in the auricular therapy was applied, there was a statistical significance in VRS and MPQ between before and after the treatment. 3. In terms of the effects of the needle electrode electrical stimulation in the auricular therapy on pain had by the non-smokers with low back pain, there was a statistical significance in VAS, VRS, and MPQ between before and after the treatment. In terms of the pain effects had by the non-smokers with low back pain when no needle electrode electrical stimulation in the auricular was applied, there was a statistical significance in VAS, VRS, and MPQ between before and after the treatment. 5. The smokers with low back pain were given the needle electrode electrical stimulation in the auricular therapy to see how it affected their pain. There was found pain reduction in number, but no statistical significance. 6. The subject suffering from low back pain were given the needle electrode electrical stimulation to see how it affected their pain according to smoking. There was found pain reduction in number, but no statistical significance. Based upon the results, it can be concluded that smokers with low back pain received the more effects of pain alleviation from the application of the needle electrode electrical stimulation in the auricular therapy compared to the rest of the groups who suffered from low back pain.