• Communications for Statistical Applications and Methods
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• 제22권4호
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• pp.361-375
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• 2015

A measure of skewness and kurtosis is proposed to test multivariate normality. It is based on an empirical standardization using the scaled residuals of the observations. First, we consider the statistics that take the skewness or the kurtosis for each coordinate of the scaled residuals. The null distributions of the statistics converge very slowly to the asymptotic distributions; therefore, we apply a transformation of the skewness or the kurtosis to univariate normality for each coordinate. Size and power are investigated through simulation; consequently, the null distributions of the statistics from the transformed ones are quite well approximated to asymptotic distributions. A simulation study also shows that the combined statistics of skewness and kurtosis have moderate sensitivity of all alternatives under study, and they might be candidates for an omnibus test.

• 품질경영학회지
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• 제39권2호
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• pp.313-319
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• 2011

In design verification and process validation stages, reliability demonstration tests(RDT's) are common practice in industry, A new two-stage RDT that is known to be more efficient than a corresponding single-stage one in terms of expected test duration for Weibull distribution is proposed. Zero or one failure two-stage plans to minimize expected test duration under Type I and hybrid censoring subject to satisfying consumer's risk at a specified reliability target are developed and a numerical example is provided to illustrate the proposed two-stage RDT plans and compared with other one- and two-stage plans.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권12호
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• pp.6161-6176
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• 2018

Pseudorandom numbers are useful in cryptographic operations for using as nonce, initial vector, secret key, etc. Security of the cryptosystem relies on the secret key parameters, so a good pseudorandom number is needed. In this paper, we have proposed a new approach for generation of pseudorandom number. This method uses the three dimensional combinational puzzle Rubik Cube for generation of random numbers. The number of possible combinations of the cube approximates to 43 quintillion. The large possible combination of the cube increases the complexity of brute force attack on the generator. The generator uses cryptographic hash function. Chaotic map is being employed for increasing random behavior. The pseudorandom sequence generated can be used for cryptographic applications. The generated sequences are tested for randomness using NIST Statistical Test Suite and other testing methods. The result of the tests and analysis proves that the generated sequences are random.

• Communications for Statistical Applications and Methods
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• 제30권3호
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• pp.227-244
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• 2023

In this paper, a depth-based nonparametric test for a multivariate two-sample scale problem is proposed. The proposed test statistic is based on the depth-induced ranks and is thus distribution-free. In this article, the depth values of data points of one sample are calculated with respect to the other sample or distribution and vice versa. A comprehensive simulation study is used to examine the performance of the proposed test for symmetric as well as skewed distributions. Comparison of the proposed test with the existing depth-based nonparametric tests is accomplished through empirical powers over different depth functions. The simulation study admits that the proposed test outperforms existing nonparametric depth-based tests for symmetric and skewed distributions. Finally, an actual life data set is used to demonstrate the applicability of the proposed test.

• Korean Journal of Radiology
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• 제25권7호
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• pp.656-661
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• 2024

Evaluating the performance of a binary diagnostic test, including artificial intelligence classification algorithms, involves measuring sensitivity, specificity, positive predictive value, and negative predictive value. Particularly when comparing the performance of two diagnostic tests applied on the same set of patients, these metrics are crucial for identifying the more accurate test. However, comparing predictive values presents statistical challenges because their denominators depend on the test outcomes, unlike the comparison of sensitivities and specificities. This paper reviews existing methods for comparing predictive values and proposes using the permutation test. The permutation test is an intuitive, non-parametric method suitable for datasets with small sample sizes. We demonstrate each method using a dataset from MRI and combined modality of mammography and ultrasound in diagnosing breast cancer.

• Communications for Statistical Applications and Methods
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• 제24권5호
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• pp.519-531
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• 2017

We consider goodness-of-fit test statistics for Weibull distributions when data are randomly censored and the parameters are unknown. Koziol and Green (Biometrika, 63, 465-474, 1976) proposed the $Cram\acute{e}r$-von Mises statistic's randomly censored version for a simple hypothesis based on the Kaplan-Meier product limit of the distribution function. We apply their idea to the other statistics based on the empirical distribution function such as the Kolmogorov-Smirnov and Liao and Shimokawa (Journal of Statistical Computation and Simulation, 64, 23-48, 1999) statistics. The latter is a hybrid of the Kolmogorov-Smirnov, $Cram\acute{e}r$-von Mises, and Anderson-Darling statistics. These statistics as well as the Koziol-Green statistic are considered as test statistics for randomly censored Weibull distributions with estimated parameters. The null distributions depend on the estimation method since the test statistics are not distribution free when the parameters are estimated. Maximum likelihood estimation and the graphical plotting method with the least squares are considered for parameter estimation. A simulation study enables the Liao-Shimokawa statistic to show a relatively high power in many alternatives; however, the null distribution heavily depends on the parameter estimation. Meanwhile, the Koziol-Green statistic provides moderate power and the null distribution does not significantly change upon the parameter estimation.

• 응용통계연구
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• 제26권3호
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• pp.401-411
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• 2013

변수들 간 인과관계는 시차 회귀방정식을 사용한 초기의 검정법 이후 새로운 통계적 기법이 계속 개발되면서 더욱 다양하고 효율적인 분석이 가능하게 되었지만 오랜 논쟁의 대상인 닭과 달걀 간 선행관계에 대한 검정은 의외로 간과되어왔다. 본 연구에서는 현대적 관점에서 두 변수 간 인과관계를 학문적으로 조명해보기 위해 사용가능한 자료를 이용하여 통계적 검정을 실시해 보았다. 두 변수 간 관계에는 구조적 변화가 발생하지 않았음이 입증되면서 사용한 검정법 모두 수준변수 및 정상변수에서 일관된 검정결과를 보이는 것으로 나타났다.

• 약학회지
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• 제44권4호
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• pp.308-314
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• 2000

Logarithmic transformation of pharmacokinetic parameters is routinely used in bioequivalence studies based on pharmacokinetic and statistical grounds by the United States Food and Drug Administration (FDA), European Committee for Proprietary Medicinal Products (CPMP), and Japanese National Institute of Health and Science (NIHS). Although it has not yet been recommended by the Korea Food and Drug Administration (KFDA), its use is becoming increasingly necessary in order to harmonize with international standards. In the present study, statistical procedures for the analysis of a bioequivalence based on the log transformation and a related SAS procedure were demonstrated in order to aid the understanding and application. The AUC parameters used in this demonstration were taken from the previous bioequivalence study for two aceclofenac tablets, which were performed in a single-dose crossover design. Analysis of variance (ANOVA), statistical power to detect 20% difference between the tablets, minimum detectable difference and confidence intervals were all assessed following log-transformation of the data. Bioequivalence of two aceclofenac tablets was then estimated based on the guideline of FDA. Considering the international effort for harmaonization of guidelines for bioequivalence tests, this approach may require a further evaluation for a future adaptation in the Korea Guidelines of Bioequivalence Tests (KGBT).

• Communications for Statistical Applications and Methods
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• 제26권5호
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• pp.431-443
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• 2019

Goodness-of-fit techniques are an important topic in statistical analysis. Censored data occur frequently in survival experiments; therefore, many studies are conducted when data are censored. In this paper we mainly consider test statistics based on the empirical distribution function (EDF) to test normal distributions with unknown location and scale parameters when data are randomly censored. The most famous EDF test statistic is the Kolmogorov-Smirnov; in addition, the quadratic statistics such as the $Cram{\acute{e}}r-von$ Mises and the Anderson-Darling statistic are well known. The $Cram{\acute{e}}r-von$ Mises statistic is generalized to randomly censored cases by Koziol and Green (Biometrika, 63, 465-474, 1976). In this paper, we generalize the Anderson-Darling statistic to randomly censored data using the Kaplan-Meier estimator as it was done by Koziol and Green. A simulation study is conducted under a particular censorship model proposed by Koziol and Green. Through a simulation study, the generalized Anderson-Darling statistic shows the best power against almost all alternatives considered among the three EDF statistics we take into account.

• Communications for Statistical Applications and Methods
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• 제5권2호
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• pp.517-529
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• 1998

When the sample size is small the robust minimum Hellinger distance (HD) estimator can have substantially poor relative efficiency at the true model. Similarly, approximating the exact null distributions of the ordinary Hellinger distance tests with the limiting chi-square distributions can be quite inappropriate in small samples. To overcome these problems Harris and Basu (1994) and Basu et at. (1996) recommended using a modified HD called penalized Hellinger distance (PHD). Lindsay (1994) and Basu et al. (1997) showed that another density based distance, namely the negative exponential disparity (NED), is a major competitor to the Hellinger distance in producing an asymptotically fully efficient and robust estimator. In this paper we investigate the small sample performance of the estimates and tests based on the NED and penalized NED (PNED). Our results indicate that, in the settings considered here, the NED, unlike the HD, produces estimators that perform very well in small samples and penalizing the NED does not help. However, in testing of hypotheses, the deviance test based on a PNED appears to achieve the best small-sample level compared to tests based on the NED, HD and PHD.