• 한방안이비인후피부과학회지
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• 제32권2호
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• pp.24-58
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• 2019

Objectives : The purpose of this study is to confirm the Efficacy and Safety of "Functional cosmetics containing Humulus japonicus Extract" on dry skin due to mild atopic dermatitis. Methods : A total of 48 patients who visited Semyung Oriental Medical Center from March 20th, 2018 to July 5th, 2018 were included in the study. In this study, the patients were treated with Functional cosmetics containing Humulus japonicus Extract and positive control group. For 6 weeks of gross examination, instrumental assessment were made before and after the study to evaluate how well the products for treatment group with positive control products for control group in recovering the dry skin barriers by mild atopic dermatitis. Results : 1. In the primary endpoint, Skin Hydration showed a statistically significant increase and Transepidermal Water Loss(TEWL) showed a statistically significant decrease in treatment group between Baseline and 6 weeks. 2. In the secondary endpoint, Skin Hydration showed a statistically significant increase in treatment group between Baseline and 3 weeks, but TEWL showed no statistical significance. 3. In the secondary endpoint, Skin Hydration showed a statistically significant increase in treatment group between 3 weeks and 6 weeks, but TEWL showed no statistical significance. 4. In the secondary endpoint, Change of Skin Hydration and TEWL between treatment and control group showed a statistical significance in 6 weeks. 5. In the secondary endpoint, Change of Skin Hydration of 1cm below the medial aspect of the elbow between treatment and control group showed a statistical significance in 3 weeks. 6. In the secondary endpoint, Change of Skin Hydration between treatment and control group showed a statistical significance in 3 weeks and 6 weeks except Center between the medial aspect of the elbow and the wrist in 3 weeks, and Change of TEWL between treatment and control group showed a statistical significance in 6 weeks. 7. To evaluate the safety of the products for the human body, Adverse events, EASI Score, Itching Symptoms Assessment, vital sign check were conducted; There were no severe adverse events during this study. And both experimental group and control group showed no abnormal level. Therefore, it is suggested that products, if used for certain period, should be safe for the human body. Conclusions : According to the above experiments, it is suggested that "Functional cosmetics containing Humulus japonicus Extract" should be effective for dry skin due to mild atopic dermatitis.

• Earthquakes and Structures
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• 제5권4호
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• pp.439-459
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• 2013

Main objective of the present study is to determine the statistical properties and suitable probability distribution functions of spectral displacements from nonlinear static and nonlinear dynamic analysis within the frame work of Monte Carlo simulation for typical low rise and high rise RC framed buildings located in zone III and zone V and designed as per Indian seismic codes. Probabilistic analysis of spectral displacement is useful for strength assessment and loss estimation. To the author's knowledge, no study is reported in literature on comparison of spectral displacement including the uncertainties in capacity and demand in Indian context. In the present study, uncertainties in capacity of the building is modeled by choosing cross sectional dimensions of beams and columns, density and compressive strength of concrete, yield strength and elastic modulus of steel and, live load as random variables. Uncertainty in demand is modeled by choosing peak ground acceleration (PGA) as a random variable. Nonlinear static analysis (NSA) and nonlinear dynamic analysis (NDA) are carried out for typical low rise and high rise reinforced concrete framed buildings using IDARC 2D computer program with the random sample input parameters. Statistical properties are obtained for spectral displacements corresponding to performance point from NSA and maximum absolute roof displacement from NDA and suitable probability distribution functions viz., normal, Weibull, lognormal are examined for goodness-of-fit. From the hypothesis test for goodness-of-fit, lognormal function is found to be suitable to represent the statistical variation of spectral displacement obtained from NSA and NDA.

• Ocean and Polar Research
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• 제33권1호
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• pp.13-20
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• 2011

Comprehensive data collection was carried out between 2001-2006 to investigate the concentration levels of chlorophyll-a, nutrients (DIN and DIP), and COD for surface waters of Korean coastal areas. A statistical analysis of these parameters was carried out on the basis of the frequency distribution of their concentration. Furthermore, the numeric grading for chlorophyll-a, DIN, DIP, and COD concentrations were derived statistically from the normalized frequency distribution of log-transformed data. The statistical grading clearly reflects the water quality characteristics of three Korean coastal water bodies (Western, Southern and Eastern coastal zones), which indicate common environmental and ecological characteristics. So, this study could provide useful information to set up the guideline for water quality assessment of Korean coasts.

• 경영정보학연구
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• 제8권2호
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• pp.211-234
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• 2006

서비스수준관리(Service Level Management)의 목적이 단순한 재무적 계약(서비스 수준협약의 계약 자체)에서 고객의 기대와 제공자의 서비스에 대한 관리 시스템(서비스 수준협약에 대한 관리시스템)으로 최근 변해가고 있다. 본 논문의 목적은 통계적 기법을 이용해서 체계적인 정보기술 서비스 수준관리 방안을 제시하는 것이다. 본 연구는 통계적 기법과 서비스 수준관리 라는 두 가지 관점에서 서비스 수준을 다루고 있다. 첫째, 통계적 기법을 이용해서 목표 서비스 수준을 설정한다. 둘째, 전체 서비스 수준에 대한 평가방법을 제시한다. 이와 같이 제시된 방법을 이용해서 기업 전략 측면에서 정보기술 아웃소싱 성과로서 종합 서비스 수준을 계량적으로 측정하는 것이 가능하다.

• Structural Engineering and Mechanics
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• 제46권4호
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• pp.459-486
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• 2013

A novel damage classification method based on wavelet packet transform and statistical analysis is developed in this study for structural health monitoring. The response signal of a structure under an impact load is normalized and then decomposed into wavelet packet components. Energies of these wavelet packet components are then calculated to obtain the energy distribution. Statistical similarity comparison based on an F-test is used to classify the structure from changes in the wavelet packet energy distribution. A statistical indicator is developed to describe the damage extent of the structure. This approach is applied to the test results from simply supported reinforced concrete beams in the laboratory. Cases with single and two damages are created from static loading, and accelerations of the structure from under impact loads are analyzed. Results show that the method can be used with no reference baseline measurement and model for the damage monitoring and assessment of the structure with alarms at a specified significance level.

• Structural Engineering and Mechanics
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• 제69권4호
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• pp.361-369
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• 2019

The determination of Paris' law parameters based on crack growth experiments is an important procedure of fatigue life assessment. However, it is a challenging task because it involves various sources of uncertainty. This paper proposes a novel probabilistic method, termed the S-N Paris law (SNPL) method, to quantify the uncertainties underlying the Paris' law parameters, by finding the best estimates of their statistical parameters from the S-N curve data using a Bayesian approach. Through a series of steps, the SNPL method determines the statistical parameters (e.g., mean and standard deviation) of the Paris' law parameters that will maximize the likelihood of observing the given S-N data. Because the SNPL method is based on a Bayesian approach, the prior statistical parameters can be updated when additional S-N test data are available. Thus, information on the Paris' law parameters can be obtained with greater reliability. The proposed method is tested by applying it to S-N curves of 40H steel and 20G steel, and the corresponding analysis results are in good agreement with the experimental observations.

• 한국추진공학회지
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• 제13권6호
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• pp.34-40
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• 2009

본 논문은 액체로켓엔진의 구성품인 연소기와 가스발생기의 연소 안정성 평가를 위한 평가 방법과 기준에 관해 서술하였다. 두 가지 평가 방법이 있는데, 첫 번째는 일반적인 정상 연소 시험을 통해 연소 안정성 여부를 판단하는 통계적인 접근 방식을 취하는 정적 평가와 두 번째로는 연소장에 압력 교란을 일으키는 장치를 이용, 생성된 펄스의 감쇠 특성을 파악하는 동적 평가가 있다. 누적된 실제 추진제 연소 시험 결과를 통해서 정적 평가의 안정성 여부는 Root-Mean-Square 값이 연소실 압력의 3%, 동적 안정성 여부는 가진된 압력 섭동의 감쇠시간이 10 msec로 기준을 설정하였다.

• 농업과학연구
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• 제47권3호
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• pp.577-596
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• 2020

Drought is a natural disaster that directly affects agriculture, which has a great impact on the global agricultural production system and yield. The lack of water storage in most parts of the country due to the lack of precipitation has caused a great increase in social interest in drought due to the dryness of rice fields and crops. As the drought period increases and the drought intensity becomes stronger, it is believed that drought damage to crops will continue; thus, it is necessary to understand the vulnerability to irrigation performance and the ability of irrigation facilities. Therefore, this study conducted a vulnerability assessment of irrigation facilities (public Groundwater well) in cities across the country. The survey was conducted using statistical data from 2007 to 2016, and the vulnerability score was calculated according to the vulnerability evaluation procedure for drought in the irrigation facilities (public groundwater wells). Among 157 regions, 136 areas were very vulnerable; 14 areas were vulnerable; 3 areas were normal; 4 areas were good, and 0 areas were excellent. The vulnerability assessment can be used as basic data for the development or maintenance of field irrigation facilities in the future by understanding the vulnerability of irrigation facilities.

• Structural Engineering and Mechanics
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• 제38권2호
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• pp.171-193
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• 2011

One of the possible alternatives of simulation-based time-dependent reliability assessment of pre-stressed biconcave and biconvex cable trusses, the Monte Carlo method, is applied in this paper. The influence of an excessive deflection of cable truss (caused by creep of cables and rheologic changes) on its time-dependent serviceability is investigated. Attention is given to the definition of the basic random variables and their statistical functions (basic, mutually dependent random variables such as the pre-stressing forces of the bottom and top cable, structural geometry, the Young's modulus of elasticity of the cables, and the independent variables, such as permanent load, wind, snow and thermal actions). Then, the determination of the response of the cable truss to the loading effects, and the definition of the limiting values considering serviceability of the structure are performed. The potential of the method, using direct Monte Carlo technique for simulation-based time-dependent reliability assessment as a powerful tool, is emphasized. Results obtained by the First order reliability method (FORM) are compared with those obtained by the Monte Carlo simulation technique.

• Journal of Preventive Medicine and Public Health
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• 제42권6호
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• pp.371-376
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• 2009

In this article, we reviewed the literature on risk assessment (RA) models with and without molecular genomic markers and the current utility of the markers in the pharmacogenetic field. Epidemiological risk assessment is applied using statistical models and equations established from current scientific knowledge of risk and disease. Several papers have reported that traditional RA tools have significant limitations in decision-making in management strategies for individuals as predictions of diseases and disease progression are inaccurate. Recently, the model added information on the genetic susceptibility factors that are expected to be most responsible for differences in individual risk. On the continuum of health care, from diagnosis to treatment, pharmacogenetics has been developed based on the accumulated knowledge of human genomic variation involving drug distribution and metabolism and the target of action, which has the potential to facilitate personalized medicine that can avoid therapeutic failure and serious side effects. There are many challenges for the applicability of genomic information in a clinical setting. Current uses of genetic markers for managing drug therapy and issues in the development of a valid biomarker in pharmacogenetics are discussed.