• 한국지능시스템학회논문지
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• 제5권4호
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• pp.3-11
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• 1995

In this paper we introduce the notions of a TL-state machines, an admissible relation and a TL-transformation semigroup and discuss their basic properties.

• Journal of Microbiology and Biotechnology
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• 제26권11호
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• pp.1924-1932
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• 2016

Mycophenolic acid (MPA) is an antibiotic produced by Penicillium brevicompactum. MPA has antifungal, antineoplastic, and immunosuppressive functions, among others. ${\beta}-Hydroxy-{\beta}-methylglutaryl-CoA$ (HMG-CoA) lyase is a key enzyme in the bypass metabolic pathway. The inhibitory activity of HMG-CoA lyase increases the MPA biosynthetic flux by reducing the generation of by-products. In this study, we cloned the P. brevicompactum HMG-CoA lyase gene using the thermal asymmetric interlaced polymerase chain reaction and gene walking technology. Agrobacterium tumefaciens-mediated transformation (ATMT) was used to insert a mutated HMG-CoA lyase gene into P. brevicompactum. Successful insertion of the HMG-CoA lyase gene was confirmed by hygromycin screening, PCR, Southern blot analysis, and enzyme content assay. The maximum MPA production by transformants was 2.94 g/l. This was 71% higher than wild-type ATCC 16024. Our results demonstrate that ATMT may be an alternative practical genetic tool for directional transformation of P. brevicompactum.

• Fibers and Polymers
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• 제1권1호
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• pp.18-24
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• 2000

The phase transformation of poly(trimethylene terephthalate) in crystalline state was simulated by atomistic modeling using molecular mechanics technique. The crystalline structure of PTT was successfully prepared using the well-defined unit cell structure of PTT and was satisfactorily verified by comparing that with the structure obtained from the x-ray diffraction experiments. The basic elastic properties were predicted in this study, showing that the crystalline structure of PTT is very pliable to the deformation at small strain. When the crystalline structure of PTT was stepwise deformed up to 50% of strain in chain direction under uniaxial extension condition, the change in dihedral angle of trimethylene unit from gg to tt conformation was accompanied with a large increase of stress, indicating that the phase transformation of PTT in crystalline state is difficult to occur.

• International Journal of Computer Science & Network Security
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• 제22권7호
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• pp.181-190
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• 2022

The article contains an overview of the results of recent research by think tanks in different countries, devoted to the analysis of economic resilience factors in the Covid-19 crisis and the development of recommendations for improving preparedness for the next crises. The authors consider and propose a theoretical framework for the concept of the resilience of economic systems. The impact of the COVID-19 crisis on national economies is analyzed. Factors explaining the different cability of economic systems to withstand shock in the short and long term are identified. The reactions of market participants and national governments to the crisis are assessed. It is shown how the COVID-19 crisis has affected the digital transformation of economic systems, and how digital transformation helps to increase the resilience of national economies so that the latter can emerge from the crisis even stronger.

• 소성∙가공
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• 제19권8호
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• pp.468-473
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• 2010

Shape memory alloys (SMAs) have the ability to recover their original shape upon thermo-mechanical loading even after large inelastic deformation. The unique feature is known as pseudoelasticity and shape memory effect caused by the crystalline structural transformation between two solid-state phases called austenite and martensite. To support the engineering application, a number of constitutive models, which can be formally classified into either micromechanics-based or phenomenological model, have been developed. Most of the constitutive models include a kinetic law governing the crystallographic transformation. The present work presents a one-dimensional, phenomenological constitutive model for SMAs in the context of the unified viscoplasticity theory. The proposed model does not incorporate the complex mechanisms of phase transformation. Instead, the effects induced by the transformation are depicted through the growth law for the back stress that is an internal state variable of the model.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1991년도 한국자동제어학술회의논문집(국제학술편); KOEX, Seoul; 22-24 Oct. 1991
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• pp.1845-1847
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• 1991

In general, it is not easy to find the linearizing coordinate transformation map for a class of systems which are state equivalent to linear systems, because it is required to solve a set of partial differential equations. It is possible to construct an arbitrary nonlinear function with a backpropagation(BP) net. Utilizing this property of BP neural net, we construct a desired linearizing coordinate transformation map. That is, we implement a unknown coordinate transformation map through the training of neural weights. We have shown an example which supports this idea.

• 오토저널
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• 제6권4호
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• pp.46-53
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• 1984

The analysis of temperature distribution and change of metallic structures during water quench were presented by finite element method. In temperature calculation the equation of unsteady state hear conduction problem considering latent heat due to phase transformation was applied to finite solid cylinder, SM 45C of 40mm diameter and 40mm height. In metallic structure analysis iso-thermal transformation curve and the equations of evolution in pearlite-martensite transformation were applied. The calculated results upon temperature and metallic structures were agreed with those of experimental observations.

• Journal of Microbiology and Biotechnology
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• 제20권1호
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• pp.39-44
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• 2010

Acidithiobacillus caldus is an acidophilic, chemolithotrophic bacterium that plays an important role in bioleaching. Gene transformation into A. caldus is difficult, and only the conjugation method was reported successful, which was a relatively sophisticated method. In this research, electrotransformation of A. caldus species was achieved for the first time using A. caldus Y-3 and plasmid pJRD215. Transformants were confirmed by colony PCR specific to the str gene on pJRD215, and the recovery of the plasmid from the presumptive transformants. Optimizations were made and the transformation efficiency was increased from 0.8 to $3.6{\times}10^4$ transformants/${\mu}g$ plasmid DNA. The developed electrotransformation method was convenient in introducing foreign genes into A. caldus.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1992년도 한국자동제어학술회의논문집(국제학술편); KOEX, Seoul; 19-21 Oct. 1992
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• pp.405-412
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• 1992

The problem we consider in this paper is more demanding than the problem of input-output linearization with state equivalence recently solved by Cheng, Isidori, Respondek, and Tarn. We request that the MIMO nonlinear system, for which the problem of input-output linearization with state-equivalence is solvable, can be decoupled. In exchange for further requirement like this, our problem produces more usable and informative results than the problem of input-output linearization with state-equivalence. We present the necessary and sufficient conditions for our problem to be solvable. We characterize each of the nonlinear systems satisfying these conditions by a set of parameters which are invariant under the group action of state feedback and transformation. Using this set of parameters, we can determine directly the unique one, among the canonical forms of decouplable and controllable linear systems, to which a nonlinear system can be transformed via appropriate state feedback and transformation. Finally, we present the necessary and sufficient conditions for our problem to be solvable with internal stability, that is, for stable decoupling.

• 대한전기학회논문지
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• 제35권4호
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• pp.148-155
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• 1986

This paper presents a new decoupled power system state estimation method. The decoupling is achieved via simple linear transformation on power measurements in contrast with the modified fast decoupled state estimation method which assumes decoupling by direct negligence of the off-diagonal blocks of the observation functions. The new estimation method is compared with the modified decoupled state estimation method against IEEE-14 bus model power system and 25 bus model power system in several system conditions. It is observed that the proposed method shows better convergence performance and filtering performance than a modified fast decoupled state estimation.