• Title/Summary/Keyword: State Structure Function

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Structure Determination of Syndecan-4 Transmembrane Domain using PISA Wheel Pattern and Molecular Dynamics simulation

  • Choi, Sung-Sub;Jeong, Ji-Ho;Kim, Ji-Sun;Kim, Yongae
    • Journal of the Korean Magnetic Resonance Society
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    • v.18 no.2
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    • pp.58-62
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    • 2014
  • Human transmembrane proteins (hTMPs) are closely related to transport, channel formation, signaling, cell to cell interaction, so they are the crucial target of modern medicinal drugs. In order to study the structure and function of these hTMPs, it is important to prepare reasonable amounts of proteins. However, their preparation is seriously difficult and time-consuming due to insufficient yields and low solubility of hTMPs. We tried to produce large amounts of Syndecan-4 transmembrane domain (Syd4-TM) that is related to the healing wounds and tumor for a long time. In this study, we performed the structure determination of Syd4-TM combining the Polarity Index at Slanted Angle (PISA) wheel pattern analysis based on $^{15}N-^1H$ 2D SAMPI-4 solid-state NMR of expressed Syd4-TM and Molecular Dynamics (MD) simulation using Discovery Studio 3.1.

Probabilistic Analysis of Dynamic Characteristics of Structures considering Joint Fastening and Tolerance (체결부 및 공차를 고려한 구조물의 확률기반 동적 특성 연구)

  • Won, Jun-Ho;Kwang, Kang-Jin;Choi, Joo-Ho
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.18 no.4
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    • pp.44-50
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    • 2010
  • Structural vibration is a significant problem in many multi-part or multi-component assemblies. In aircraft industry, structures are composed of various fasteners, such as bolts, snap, hinge, weld or other fastener or connector (collectively "fasteners"). Due to these, prediction and design involving dynamic characteristics is quite complicated. However, the current state of the art does not provide an analytical tool to effectively predict structure's dynamic characteristics, because consideration of structural uncertainties (i.e. material properties, geometric tolerance, dimensional tolerance, environment and so on) is difficult and very small fasteners in the structure cause a huge amount of analysis time to predict dynamic characteristics using the FEM (finite element method). In this study, to resolve the current state of the art, a new approach is proposed using the FEM and probabilistic analysis. Firstly, equivalent elements are developed using simple element (e.g. bar, beam, mass) to replace fasteners' finite element model. Developed equivalent elements enable to explain static behavior and dynamic behavior of the structure. Secondly, probabilistic analysis is applied to evaluate the PDF (probability density function) of dynamic characteristics due to tolerance, material properties and so on. MCS (Monte-Carlo simulation) is employed for this. Proposed methodology offers efficiency of dynamic analysis and reality of the field as well. Simple plates joined by fasteners are taken as an example to illustrate the proposed method.

Analysis of the Behavior of Complemented TPNCA Derived from a Linear TPNCA (선형 TPNCA로부터 얻어지는 여원 TPNCA의 행동분석)

  • 조성진;최언숙;황윤희;김한두;허성훈
    • Journal of Korea Multimedia Society
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    • v.6 no.3
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    • pp.549-555
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    • 2003
  • CA is cost-effective to generate pseudorandom patterns than LFSR. Based on the effectiveness of a CA based pseudorandom pattern generator, CA have been employed successfully in several applications. Especially Nongroup CA is applied to efficient hash function generation, cryptography and image compression. In this paper we analyze the properties of TPNCA and by using basic paths in the 0-tree of a linear TPNCA we analyze the structure of the state-transition graph. Also by showing the structure of the complemented CA which have the acyclic state of the 0-tree as the complement vector is isomorphic to the structure of the original TPNCA, we reduce the time in analyzing the CA-states.

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Development and Implementation of Measures for Structural and Reliability Importance by Using Minimal Cut Sets and Minimal Path Sets (최소절단집합과 최소경로집합을 이용한 구조 및 신뢰성 중요도 척도의 개발 및 적용)

  • Choi, Sung-Woon
    • Journal of the Korea Safety Management & Science
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    • v.14 no.1
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    • pp.225-233
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    • 2012
  • The research discusses interrelationship of structural and reliability importance measures which used in the probabilistic safety assessment. The most frequently used component importance measures, such as Birnbaum's Importance (BI), Risk Reduction (RR), Risk Reduction Worth (RRW), RA (Risk Achievement), Risk Achievement Worth (RAW), Fussel Vesely (FV) and Critically Importance (CI) can be derived from two structure importance measures that are developed based on the size and the number of Minimal Path Set (MPS) and Minimal Cut Set (MCS). In order to show an effectiveness of importance measures which is developed in this paper, the three representative functional structures, such as series-parallel, k out of n and bridge are used to compare with Birnbaum's Importance measure. In addition, the study presents the implementation examples of Total Productive Maintenance (TPM) metrics and alternating renewal process models with exponential distribution to calculate the availability and unavailability of component facility for improving system performances. System state structure functions in terms of component states can be converted into the system availability (unavailability) functions by substituting the component reliabilities (unavailabilities) for the component states. The applicable examples are presented in order to help the understanding of practitioners.

Seismic performance-based optimal design approach for structures equipped with SATMDs

  • Mohebbi, Mohtasham;Bakhshinezhad, Sina
    • Earthquakes and Structures
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    • v.22 no.1
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    • pp.95-107
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    • 2022
  • This paper introduces a novel, rigorous, and efficient probabilistic methodology for the performance-based optimal design (PBOD) of semi-active tuned mass damper (SATMD) for seismically excited nonlinear structures. The proposed methodology is consistent with the modern performance-based earthquake engineering framework and aims to design reliable control systems. To this end, an optimization problem has been defined which considers the parameters of control systems as design variables and minimization of the probability of exceeding a targeted structural performance level during the lifetime as an objective function with a constraint on the failure probability of stroke length damage state associated with mass damper mechanism. The effectiveness of the proposed methodology is illustrated through a numerical example of performance analysis of an eight-story nonlinear shear building frame with hysteretic bilinear behavior. The SATMD with variable stiffness and damping have been designed separately with different mass ratios. Their performance has been compared with that of uncontrolled structure and the structure controlled with passive TMD in terms of probabilistic demand curves, response hazard curves, fragility curves, and exceedance probability of performance levels during the lifetime. Numerical results show the effectiveness, simplicity, and reliability of the proposed PBOD method in designing SATMD with variable stiffness and damping for the nonlinear frames where they have reduced the exceedance probability of the structure up to 49% and 44%, respectively.

A Study on The Protection Organization for The Chief of State in North and South Korea (${\cdot}$북한의 국가원수 경호조직에 관한 연구)

  • Kim, Doo-Hyun
    • Korean Security Journal
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    • no.1
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    • pp.17-50
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    • 1997
  • I study on the security organization for the chief of state in North and South Korea. The paper, purporting to analyze security system in comparative prospectives, comprise four chapters. Chapter I Which sets out purpose, scope and method, is followed by Chapter II , dealing largely with the power structure on The Socialist Constitution of Democratic People's Republic of Korea, the protection organization and security activities for the chief of state in North Korea. Chapter III concerns the security environment - terrorist groups, firearms, explosives, suspects, movements of hostile countries and orthers - and the protection organization on The Presidential Security Service for the president in South Korea, culminating in projection of certain problem area. It is followed by concluding observation made in Chapter IV. To be operated security systems effectively, these need to be regulated according to a protective scale, function, authority of a existing.

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A Robust Sliding Mode Controller for Unmatched Uncertain Severe Sate Time-Delay Systems (큰 상태변수 시간 지연 부정합조건 불확실성 시스템을 위한 강인한 슬라이딩 모드 제어기)

  • Lee, Jung-Hoon
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.10
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    • pp.1894-1899
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    • 2010
  • This note is concerned with a robust sliding mode control(SMC) for a class of unmatched uncertain system with severe commensurate state time delay. The suggested method is extended to the control of severe state time delay systems with unmatched uncertainties except the matched input matrix uncertainty. A transformed sliding surface is proposed and a stabilizing control input is suggested. The closed loop stability together with the existence condition of the sliding mode on the proposed sliding surface is investigated through one Lemma and two Theorems by using the Lyapunov direct method with the concept of the control Lyapunov function instead of complex Lyapunov-Kravoskii functionals. Through an illustrative example and simulation study, the usefulness of the main results is verified.

State- and Output-feedback Adaptive Controller for Pure-feedback Nonlinear Systems using Self-structuring Fuzzy System (완전 궤환 비선형 계통에 대한 자기 구조화 퍼지 시스템을 이용한 상태변수 및 출력 궤환 적응 제어기)

  • Park, Jang-Hyun;Kim, Seong-Hwan;Jang, Young-Hak;Ryoo, Young-Jae
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.61 no.9
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    • pp.1319-1329
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    • 2012
  • Globally stabilizing adaptive fuzzy state- and output-feedback controllers for the fully nonaffine pure-feedback nonlinear system are proposed in this paper. By reformulating the original pure-feedback system to a standard normal form with respect to newly defined state variables, the proposed controllers require no backstepping design procedures. Avoiding backstepping makes the controller structure and stability analysis to be considerably simplified. For the global stabilty of the clossed-loop system, the self-structuring fuzzy system whose memebership functions and fuzzy rules are automatically generated and tuned is adopted. The proposed controllers employ only one fuzzy logic system to approximate unknown nonlinear function, which highlights the simplicity of the proposed adaptive fuzzy controller. Moreover, the output-feedback controller of the considered system proposed in this paper have not been dealt with in any literature yet.

Evaluation of Performance Measures for Redundant Systems

  • Shin, Sang-Wook;Lee, Chong-Hyung;Lee, Jae-Hak;Park, Dong-Ho
    • International Journal of Reliability and Applications
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    • v.2 no.2
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    • pp.107-115
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    • 2001
  • This paper considers some reliability indices, such as availability, average availability, reliability and steady state availability, of a redundant system with the function of switchover processing. We also derive the confidence limits for steady state availability of such system. The system, which is considered in this paper, consists of an active unit, a standby unit and a switchover device. In addition, the switchover processing is controlled by a control module. The effect of failure of the control module is taken into account to develop our reliability model for the redundant structure. Numerical examples are presented to illustrate our results.

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Effect of Doping State on Photoresponse Properties of Polypyrrole

  • Choi, Jongwan
    • Elastomers and Composites
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    • v.56 no.4
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    • pp.250-253
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    • 2021
  • Polypyrrole is an organic thermoelectric material which has been receiving extensive attention in recent years. Polypyrrole is applicable in various fields because its electrical properties are controllable by its doping concentration. In this study, the effects of the polypyrrole doping state on its photoresponse were investigated. The degree of doping was controlled by ammonia solution treatment. Then, the chemical structure as a function of the doping states was observed by Raman analysis. Moreover, the photocurrent and photovoltage characteristics for various doping states were measured by an asymmetrically irradiated light source. As the degree of doping increased, the electrical conductivity increased, which affected the photocurrent. Meanwhile, the photovoltage was related to the temperature gradient caused by light irradiation.