• Clinical and Experimental Reproductive Medicine
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• 제48권3호
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• pp.229-235
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• 2021

Objective: In this study, the effects of Lactobacillus acidophilus on testosterone (TES), follicle-stimulating hormone (FSH), luteinizing hormone (LH), androgen-binding protein (ABP), factor-associated apoptosis (FAS), and total cholesterol (TC), as well as histopathological changes, were investigated in male rats fed a high-cholesterol diet. Methods: The study included three groups. The control (C) group was fed standard-diet for 8 weeks. The hypercholesterolemia (HC) group was fed a 2% cholesterol-diet for 8 weeks. The therapeutic group (HCL) was fed a 2% cholesterol-diet for 8 weeks and administered L. acidophilus for the last 4 weeks. FSH, TES, and FAS levels in testicular tissue were determined using an enzyme-linked immunosorbent assay (ELISA), while another sample was examined histopathologically. LH and ABP levels were determined using ELISA, and serum TC levels were assessed via an autoanalyzer. Results: In the HC group, the TC levels were significantly higher and the LH levels were lower (p<0.05) than in the C group. The ABP levels were lower (p>0.05). In the HCL group, the LH and ABP levels were higher (p>0.05) and the TC level significantly lower (p<0.05) than in the HC group. The TES and FSH levels were lower, and the FAS levels were higher, in the HC than in the C group (p<0.05). In the HCL group, levels of all three resembled control levels. Histologically, in the testicular tissue of the HC group, the cells in the tubular wall exhibited atrophy, vacuolization, and reduced wall structure integrity. However, in the HCL group, these deteriorations were largely reversed. Conclusion: Supplementary dietary administration of an L. acidophilus to hypercholesterolemic male rats positively impacted testicular tissue and male fertility hormone levels.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회B
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• pp.2642-2647
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• 2008

Starting characteristics of the axi-symmetric supersonic exhaust diffuser(SED) with a second throat are numerically investigated. Main purpose of this study is to predict theoretical starting pressure of STED using 1-D normal shock theory and to present the range of optimum starting pressure through parametric study with essential design parameters of STED influencing on starting performance. Renolds-Average Navier-Stokes equations with a standard ${\kappa}-{\varepsilon}$ turbulence model incorporated with standard wall function are solved to simulate the diffusing evolutions of the nozzle plume. Minimum(optimum) starting pressure difference of $20{\sim}25%$ between 1-D theory and experimental evidences validated from previous results[5] is also applied to predict those in this system. The analysis results indicate that dominant parameters for diffuser starting in this system is diffuser expansion ratio($A_d/A_t$), which has optimum value 120 and second throat area ratio($A_d/A_{st}$), which has optimum range $3.3{\sim}3.5$.

• 한국CDE학회논문집
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• 제13권4호
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• pp.286-295
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• 2008

Construction industry, which is a composite industry being performed by organic combination of various tasks, gives birth to a various of information in the stages of planning, designing, and maintenance management. In particular, the drawing information is broad in the scope of use because it contains all information about buildings as wall as bid, materials, contracts. Therefore, the management of drawing information security is one of the most important factors, which determines the success of failure of business. The major findings and result of this study are as follows to control the distributed drawing information in the collaboration environment. 1) Analysis for function and practical use of DRM in the construction industry. 2) Proposal for applications of DRM that can secure IFC model-based drawing information in the collaboration environment. 3) Extraction from additional IFC entities to apply DRM to part 21 physical files 4) Analysis for functions which are necessary in DRM application prototype system and development of the system. 5) Development IFC model-based DRM prototype system.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2003년도 The Fifth Asian Computational Fluid Dynamics Conference
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• pp.237-239
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• 2003

The present study investigates on design optimization of rib-roughened two-dimensional channel to enhance turbulent heat transfer. Response surface method with Reynolds-averaged Navier-Stokes analysis is used as an optimization technique. Standard $k-{\varepsilon}$model with wall functions is adopted as a turbulence closure. The objective function is defined as a linear combination of heat transfer and friction drag coefficients with weighting factor. Computational results for overall heat transfer rate show good agreements with experimental data. Four design variables are optimized for weighting factor of 0.02.

• International Journal of Fluid Machinery and Systems
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• 제4권1호
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• pp.133-139
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• 2011

In this paper, Based on Two-dimensional Flow Theory, adopting quasi-orthogonal method and point-by-point integration method to design the impeller of the low specific speed centrifugal pump by code, and using RANS (Reynolds Averaged N-S) Equation with a standard k-${\varepsilon}$ two-equation turbulence model and log-law wall function to solve 3D turbulent flow field in the impeller of the low specific speed pump. An analysis of the influences of the blade profile on velocity distributions, pressure distributions and pump performance and the investigation of the flow regulation pattern in the impeller of the centrifugal pump are presented. And the result shows that this method can be used as a new way in low speed centrifugal pump impeller design.

• Advances in aircraft and spacecraft science
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• 제7권3호
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• pp.187-202
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• 2020

The exhaust nozzle serves back pressure of Pulse detonation combustor, so combustion chamber gets sufficient pressure for propulsion. In this context recent researches are focused on influence of nozzle effect on single cycle detonation wave propagation and propulsion performance of PDE. The effects of various nozzles like convergent-divergent nozzle, convergent nozzle, divergent nozzle and without nozzle at exit section of detonation tubes were computationally investigated to seek the desired propulsion performance. Further the effect of divergent nozzle length and half angle on detonation wave structure was analyzed. The simulations have been done using Ansys 14 Fluent platform. The LES turbulence model was used to simulate the combustion wave reacting flows in combustor with standard wall function. From these numerical simulations among four acquaint nozzles the highest thrust augmentation could be attained in divergent nozzle geometry and detonation wave propagation velocity eventually reaches to 1830 m/s, which is near about C-J velocity. Smaller the divergent nozzle half angle has a significant effect on faster detonation wave propagation.

• 한국실내디자인학회논문집
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• 제19권5호
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• pp.21-28
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• 2010

This study is purposed to understand the spacial usage of the furniture in detail for interior architecture. Many documents have prescribed the spacial furniture at random. While modernist have been interested in the spacial usage of the furniture, the importance of the spacial furniture stands out in architectural space. Since long ago, a great deal of effort has been put into creating a relational harmony between the space and furniture. The villa, the weekend home of the Savoye family, was built between 1928 and 1931. Particularly, the villa Savoye was focused for this study. Le Corbusier viewed desks and case pieces for storage as architecture, and the unite furniture and architecture by developing cabinets in standard modules that could be painted either the wall color to become part of the wall or in contrasting colors to stand out as furniture. Spacial furniture was used architecturally in the interior as well, it gives the space an unexpected playfulness with the color of the finishing materials. The various usage of the Spacial furniture constitute an element of great architectural richness. They have a unique principle based on emotional order and make the man move to another space and experience the spacial connection. In particular, the furniture that was considered by Corbuisier have rational function, division of the space, leaning the structure, and so on. The furniture as the element of the space composition can change the architectural space and view as well as connecting each other. Spacial furniture appear as physical ones called wall, floor, column, and existential value as a living space.

• 한국구조물진단유지관리공학회 논문집
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• 제18권2호
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• pp.1-8
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• 2014

본 연구의 목적은 경계요소를 갖는 철근콘크리트 전단벽의 잠재소성힌지길이를 합리적으로 평가할 수 있는 단순모델의 제시이다. 전단벽의 높이에 따른 이상화된 곡률분포로부터, 기본방정식은 항복모멘트와 최대모멘트 그리고 사인장균열에 의한 부가모멘트의 함수로 일반화되었다. 전단벽의 항복모멘트와 최대모멘트는 변형률 적합조건과 힘의 평형조건을 기반하여 산정하였다. 사인장균열 발생의 여부는 ACI 318-11에서 제시된 콘크리트의 전단력으로부터 검토되었으며, 부가모멘트는 Park and Paulay에 의해 제시된 트러스기구를 이용하여 산정하였다. 이들 모멘트식들은 다양한 변수범위에서 변수연구를 수행하였다. 결과적으로 등가소성힌지길이는 주철근 및 수직철근지수와 축력지수의 함수로 제시될 수 있었다. 제시된 등가소성힌지길이의 모델은 실험결과의 비교에서 평균 및 표준편차가 각각 1.019와 0.102로 실험 결과를 정확하게 예측하였다.

• 한국실내디자인학회논문집
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• 제20권5호
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• pp.13-22
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• 2011

The purpose of this study is to analyze Alva Aalto's libraries for understanding his efficient induction of natural light. To fulfill this purpose, Alvar Aalto's thought about library and natural light are examined through his working years and building types. The comparison of his libraries on usage of natural light shows different ways of natural light induction based on different locations and programs of libraries. Similarities and differences of Alvar Aalto's library architecture have strong relationship to the usage of natural light in libraries because Alvar Aalto himself regard reading as the core function of library and the efficient use of natural light is the main key of reading. In his natural light planning, regional characteristics including environmental factors and programmatic differences act as a basic standard for natural light plan. Especially, altitude of sun and its path, seasonal features affect the induction way of natural light. While conical skylights used at Viipuri library shows the characteristics of universality in Modernism architecture, later libraries presents not only various kinds of pan-shape plan but different ways of inducing natural light in according to appropriate function. From conical skylight to monitor with curved reflection wall make it possible shed diffused light to reading space and this affects to form Alvar Aalto's organic architecture. As a result, using natural light in Alvar Aalto's library architecture act as the core of forming library concepts and their development.

• 대한핵의학회지
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• 제37권4호
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• pp.207-218
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• 2003

Myocardial perfusion imaging has been increasingly used to provide prognostic data and guidance on the choice of appropriate management of patients with known or suspected coronary artery disease. The electrocardiogram gated myocardial SPECT program is corning into wide use with an advent of $^{99m}Tc-labeled$ tracers and an improvement of SPECT machines. The gated technique permits measurement of important cardiac prognostic indicators without any further discomforts or radiation burden in patients underwent standard myocardial perfusion SPECT. In addition, gated study significantly improves diagnostic yield by reducing the number of borderline interpretations and could find myocardial stunning and viable myocardium. Gated single photon emission computed tomography (SPECT) imaging allows the automated calculation of end-diastolic volume, end-systolic volume, ejection fraction, myocardial mass and the assessment of regional wall motion and thickening, and it have dramatically improved assessment of coronary artery disease in routine nuclear practice. This allows the simultaneous assessment of both perfusion and function within the same acquisition, and serves as a cost-effective technique for providing more diagnostic data with fewer diagnostic tests. Because the diagnostic and prognostic power derived from knowledge of left ventricular function can be added to that provided by assessing myocardial perfusion, gated SPECT imaging has rapidly gained widespread acceptance and is now used on a routine clinical basis in a growing number of laboratories, including South Korea. The gated SPECT technique for measurement of left ventricular parameters has been validated against a variety of well established techniques. In this work, overview of gated myocardial perfusion SPECT focus on functional parameters is presented.