• Title/Summary/Keyword: Standard Reference Model Analysis

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Effects of Expert-Determined Reference Standards in Evaluating the Diagnostic Performance of a Deep Learning Model: A Malignant Lung Nodule Detection Task on Chest Radiographs

  • Jung Eun Huh; Jong Hyuk Lee;Eui Jin Hwang;Chang Min Park
    • Korean Journal of Radiology
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    • v.24 no.2
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    • pp.155-165
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    • 2023
  • Objective: Little is known about the effects of using different expert-determined reference standards when evaluating the performance of deep learning-based automatic detection (DLAD) models and their added value to radiologists. We assessed the concordance of expert-determined standards with a clinical gold standard (herein, pathological confirmation) and the effects of different expert-determined reference standards on the estimates of radiologists' diagnostic performance to detect malignant pulmonary nodules on chest radiographs with and without the assistance of a DLAD model. Materials and Methods: This study included chest radiographs from 50 patients with pathologically proven lung cancer and 50 controls. Five expert-determined standards were constructed using the interpretations of 10 experts: individual judgment by the most experienced expert, majority vote, consensus judgments of two and three experts, and a latent class analysis (LCA) model. In separate reader tests, additional 10 radiologists independently interpreted the radiographs and then assisted with the DLAD model. Their diagnostic performance was estimated using the clinical gold standard and various expert-determined standards as the reference standard, and the results were compared using the t test with Bonferroni correction. Results: The LCA model (sensitivity, 72.6%; specificity, 100%) was most similar to the clinical gold standard. When expert-determined standards were used, the sensitivities of radiologists and DLAD model alone were overestimated, and their specificities were underestimated (all p-values < 0.05). DLAD assistance diminished the overestimation of sensitivity but exaggerated the underestimation of specificity (all p-values < 0.001). The DLAD model improved sensitivity and specificity to a greater extent when using the clinical gold standard than when using the expert-determined standards (all p-values < 0.001), except for sensitivity with the LCA model (p = 0.094). Conclusion: The LCA model was most similar to the clinical gold standard for malignant pulmonary nodule detection on chest radiographs. Expert-determined standards caused bias in measuring the diagnostic performance of the artificial intelligence model.

Developing a Standard Costing Model for a Container Terminal and Their Profitability Analysis case study of with reference to PECT and GCT (컨테이너부두의 표준원가모델 구축 및 운영수지분석)

  • 임종길;이태우
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 1999.10a
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    • pp.19-33
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    • 1999
  • This paper is concerned with developing a standard costing model based on the case study of PECT and GCT and analysing their profitability in order to improve operation efficiency and design business strategy. In doing so, the model can be a useful tool to analyze current calculation system of lease charge at the two terminals and to judge whether the level of lease charge currently applied to them is justifiable for their profitability. This paper also deals with break-even analysis of container terminal operating companies on the basis of the model and forecast of their profitability. On the top of that, it tries to look into the arguments and to suggest proposals for improving their profitability.

Standard Reference Model Analysis for Smart Farming based on Networks (네트워크 기반에서의 스마트 농업 표준 기준모델 분석)

  • Kim, Dong Il;Chung, Hee Chang
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.11
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    • pp.2703-2709
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    • 2015
  • IT convergence with agriculture is expected to bring more efficiency and quality improvement in producing, distributing, consuming of agricultural products with the aid of information processing and autonomous control technologies of the IT area. Smart Farming based on network is a service which is capable of coping with environmental and technical problems with the actualized IT convergence case for agriculture. In this paper, it is required to consider the actualized IT convergence case for agriculture, namely Smart Farming as a solution to cope the presented problems. In addition, propose and suggest to standard model and standardization items requirement for the Smart Farming based on network.

A Numerical Study on the Flow Uniformity according to Chamber Shapes Used for Test of the Semi-Conductor Chip (반도체 칩 테스트용 챔버 형상에 따른 유동 균일성에 대한 수치적 연구)

  • LEE, DAEGYU;MA, SANG-BUM;KIM, SUNG;KIM, JEONG-YEOL;KANG, CHAEDONG;KIM, JIN-HYUK
    • Transactions of the Korean hydrogen and new energy society
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    • v.31 no.5
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    • pp.480-488
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    • 2020
  • This study was conducted to improve the flow uniformity inside the chip tester through changing the flow path formation according to the inlet and outlet position of chamber. The internal flow and velocity distributions of the modified chamber models (Cases 1-3) were compared with the reference chamber model through three-dimensional Reynolds-averaged Navier-Stokes equations with k-ε turbulence model. The modified chamber models showed the superior flow uniformity characteristics compared to the reference chamber model. To investigate the flow uniformity in the chip tester, the standard deviation of the velocity was defined and compared. Through the internal flow analysis and assesment of the standard deviation, Case 2 among the test cases including the reference model showed the best flow uniformity generally.

Accurate Measurement of Arsenic in Laver by Gravimetric Standard Addition Method Combined with High Resolution Inductively Coupled Plasma Mass Spectrometry

  • Lee, Kyoung-Seok;Kim, Hyeon-Ji;Yim, Yong-Hyeon;Kim, Jeongkwon;Hwang, Euijin
    • Mass Spectrometry Letters
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    • v.5 no.2
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    • pp.57-61
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    • 2014
  • A gravimetric standard addition method combined with internal standard calibration has been successfully developed for the accurate analysis of total arsenic in a laver candidate reference material. A model equation for the gravimetric standard addition approach using an internal standard was derived to determine arsenic content in samples. Handlings of samples, As standard and internal standard were carried out gravimetrically to avoid larger uncertainty and variability involved in the volumetric preparation. Germanium was selected as the internal standard because of its close mass to the arsenic to minimize mass-dependent bias in mass spectrometer. The ion signal ratios of $^{75}As^+$ to $^{72}Ge^+$ (or $^{73}Ge^+$) were measured in high resolution mode ($R{\geq}10,000$) to separate potential isobaric interferences by high resolution ICP/MS. For method validation, the developed method was applied to the analysis of arsenic content in the NMIJ 7402-a codfish certified reference material (CRM) and the result was $37.07mg{\cdot}kg^{-1}{\pm}0.45mg{\cdot}kg^{-1}$ which is in good agreement with the certified value, $36.7mg{\cdot}kg^{-1}{\pm}1.8mg{\cdot}kg^{-1}$. Finally, the certified value of the total arsenic in the candidate laver CRM was determined to be $47.15mg{\cdot}kg^{-1}{\pm}1.32mg{\cdot}kg^{-1}$ (k = 2.8 for 95% confidence level) which is an excellent result for arsenic measurement with only 2.8 % of relative expanded uncertainty.

CFD evaluation of a suitable site for a wind turbine on a trapezoid shaped hill

  • Unchai, Thitipong;Janyalertadun, Adun
    • Wind and Structures
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    • v.19 no.1
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    • pp.75-88
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    • 2014
  • The computational fluid dynamic is used to explore new aspects of the hill flow. This analysis focuses on flow dependency and the comparison of results from measurements and simulations to show an optimization turbulent model and the possibility of replacing measurements with simulations. The first half of the paper investigates a suitable turbulence model for determining a suitable site for a wind turbine. Results of the standard k-${\varepsilon}$ model are compared precisely with the measurements taken in front of the hilltop, The Reynolds Stress Model showed exact results after 1.0 times of hill steepness but the standard k-${\varepsilon}$ model and standard k-${\omega}$ model showed greater underestimation. In addition, velocity flow over Pha Taem hill topography and the reference geometry shape were compared to find a suitable site for a turbine in case the actual hill structure was associated with the trapezoid geometric shape. Further study of geometry shaped hills and suitable sites for wind turbines will be reported elsewhere.

A novel reference model for dental scanning system evaluation: analysis of five intraoral scanners

  • Karakas-Stupar, Irina;Zitzmann, Nicola Ursula;Joda, Tim
    • The Journal of Advanced Prosthodontics
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    • v.14 no.2
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    • pp.63-69
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    • 2022
  • PURPOSE. The aim of this in vitro study was to investigate the accuracy (trueness and precision) of five intraoral scanners (IOS) using a novel reference model for standardized performance evaluation. MATERIALS AND METHODS. Five IOSs (Medit i500, Omnicam, Primescan, Trios 3, Trios 4) were used to digitize the reference model, which represented a simplified full-arch situation with four abutment teeth. Each IOS was used five times by an experienced operator, resulting in 25 STL (Standard Tessellation Language) files. STL data were imported into 3D software (Final Surface®) and examined for inter- and intra-group analyses. Deviations in the parameter matching error were calculated. ANOVA F-test and Kruskal-Wallis test were applied for inter-group comparisons (α = .05); and the coefficient of variation (CV) was calculated for intra-group comparisons (in % ± SD). RESULTS. Primescan (matching error value: 0.015), Trios 3 (0.016), and Trios 4 (0.018) revealed comparable results with significantly higher accuracy compared to Medit i500 (0.035) and Omnicam (0.028) (P < .001). For intra-group comparison, Trios 4 demonstrated the most homogenous results (CV 15.8%). CONCLUSION. The novel reference model investigated in this study can be used to assess the performance of dental scanning technologies in the daily routine setting and in research settings.

ANALYSIS OF ASTRONOMICAL ALMANAC DATA FOR NATIONAL STANDARD REFERENCE DATA (참조표준 등록을 위한 천문역법 자료 분석)

  • Yang, Hong-Jin;Ahn, Young-Sook;Lee, Ki-Won
    • Publications of The Korean Astronomical Society
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    • v.23 no.2
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    • pp.53-63
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    • 2008
  • Korea Astronomy and Space Science Institute (KASI), direct decendant of Korea National Astronomy Observatory, has been publishing Korean Astronomical Almanac since in 1976. The almanac contains essential data in our daily lives such as the times of sunrise, sunset, moonrise, and moonset, conversion tables between luni-solar and solar calendars, and so forth. So, we are planning to register Korean astronomical almanac data for national Standard Reference Data(SRD), which is a scientific/technical data whose the reliablity and the accuracy are authorized by scientific analysis and evalution. To be certificated as national SRD, reference data has to satisfy several criteria such as traceability, consistency, uncertainty, and so on. Based on similarity among calculation processes, we classified astronomical almanac data into three groups: Class I, II, and III. We are planning to register them for national SRD in consecutive order. In this study, we analyzed Class I data which is aimed to register in 2009, and presented the results. Firstly, we found that the traceability and the consistency can be ensured by the usage of NASA/JPL DE405 ephemeris and by the comparsion with international data, respectively. To evaluate uncertainty in Class I data, we solved the mathematical model and determined the factors influencing the calculations. As a result, we found that the atmospheric refraction is the main factor and leads to a variation of ${\pm}16$ seconds in the times of sunrise and sunset. We also briefly review the histories of astronomical almanac data and of standard reference data in Korea.

Use of preoperative cone-beam computed tomography to aid in establishment of endodontic working length: A systematic review and meta-analysis

  • Paterson, Andrew;Franco, Vittorio;Patel, Shanon;Foschi, Federico
    • Imaging Science in Dentistry
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    • v.50 no.3
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    • pp.183-192
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    • 2020
  • Purpose: This study was performed to assess the accuracy of preoperative cone-beam computed tomography (CBCT), when justified for other reasons, in locating the apical foramen and establishing the working length. Materials and Methods: Six electronic databases were searched for studies on this subject. All studies, of any type, were included if they compared measurements of working length with preoperative CBCT to measurements using an electronic apex locator (EAL) or histological reference standard. Due to the high levels of heterogeneity, an inverse-variance random-effects model was chosen, and weighted mean differences were obtained with 95% confidence intervals and P values. Results: Nine studies were included. Compared to a histological reference standard, CBCT indicated that the apical foramen was on average 0.40 mm coronal of its histological position, with a mean absolute difference of 0.48 mm. Comparisons were also performed to an EAL reference standard, but the conclusions could not be considered robust due to high levels of heterogeneity in the results. Conclusion: A low level of evidence is produced suggesting that preoperative CBCT shows the apical foramen to be on average 0.40 mm coronal to its histological position, with a mean absolute difference of 0.48 mm.

개방형 로봇제어를 위한 표준기준모델에 관한 연구

  • 김호철;홍금식;이석희
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1995.10a
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    • pp.872-875
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    • 1995
  • The strategy of open architecture control system intends to integrate manufacturing components on a single platform, so that a particular component can be easily added and/or replaced. Therefore, the control scheme is neither hardware dependent nor software dependent. In this paper a modular and object oriented approach for the open architecture structure of control systems is invesigated. A standard reference model for genetic manufacturer system, which consists of three modules; hardware module, operating system module, and application software module, is first proposed. Then a standard reference model for open architecture robot control system is suggested.

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